Page last updated: 2024-11-04

sevoflurane and Depression

sevoflurane has been researched along with Depression in 4 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Sevoflurane anesthesia impaired cognitive functions, as well as metabotropic glutamate receptor-dependent long-term depression, through elevated surface expression of small conductance calcium-activated potassium type 2 channels."7.91Sevoflurane anesthesia impairs metabotropic glutamate receptor-dependent long-term depression and cognitive functions in senile mice. ( Shi, J; Yu, X; Zhang, F, 2019)
"Sevoflurane anesthesia impaired cognitive functions, as well as metabotropic glutamate receptor-dependent long-term depression, through elevated surface expression of small conductance calcium-activated potassium type 2 channels."3.91Sevoflurane anesthesia impairs metabotropic glutamate receptor-dependent long-term depression and cognitive functions in senile mice. ( Shi, J; Yu, X; Zhang, F, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Feng, M1
Cheng, S1
Fang, Y1
Lv, L1
Guo, P1
Wang, S1
Chen, H1
Yu, X1
Zhang, F1
Shi, J1
Zhang, H1
Li, L1
Sun, Y1
Zhang, X1
Zhang, Y1
Xu, S1
Zhao, P1
Liu, T1
Iohom, G1
Szarvas, S1
Larney, V1
O'Brien, J1
Buckley, E1
Butler, M1
Shorten, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939]15 participants (Anticipated)Interventional2021-08-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for sevoflurane and Depression

ArticleYear
Perioperative plasma concentrations of stable nitric oxide products are predictive of cognitive dysfunction after laparoscopic cholecystectomy.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:4

    Topics: Adult; Affect; Aged; Aged, 80 and over; Algorithms; Anesthesia, Inhalation; Anesthetics, Inhalation;

2004

Other Studies

3 other studies available for sevoflurane and Depression

ArticleYear
Augmentation of Sevoflurane inhalation for treatment-resistant depression with different features: A case series.
    Asian journal of psychiatry, 2023, Volume: 82

    Topics: Antidepressive Agents; Antipsychotic Agents; Depression; Depressive Disorder, Treatment-Resistant; D

2023
Sevoflurane anesthesia impairs metabotropic glutamate receptor-dependent long-term depression and cognitive functions in senile mice.
    Geriatrics & gerontology international, 2019, Volume: 19, Issue:4

    Topics: Aging; Anesthesia; Anesthetics, Inhalation; Animals; Cognition; Cognitive Dysfunction; Depression; E

2019
Sevoflurane prevents stroke-induced depressive and anxiety behaviors by promoting cannabinoid receptor subtype I-dependent interaction between β-arrestin 2 and extracellular signal-regulated kinases 1/2 in the rat hippocampus.
    Journal of neurochemistry, 2016, Volume: 137, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Anxiety; beta-Arrestin 2; Depression; Dose-Response Relationship,

2016