pargyline has been researched along with Depression in 24 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe an animal model of long-term depression based on active immunization of albino rats against BSA-conjugated inhibitor of monoamine oxidase, antidepressant, pargyline." | 7.70 | Pargyline conjugate-induced long-term activation of monoamine oxidase as an immunological model for depression. ( Ashmarin, IP; Belopolskaya, MV; Danilova, RA; Moskvityna, TA; Obukhova, MF, 1999) |
| "Behavioral depression produced by exposing animals to a stressor that they cannot control (uncontrollable shock) was reversed by infusion of the monoamine oxidase (MAO) inhibitor pargyline into the locus coeruleus (LC) region of the brain stem." | 3.67 | Infusion of a monoamine oxidase inhibitor into the locus coeruleus can prevent stress-induced behavioral depression. ( Ambrose, MJ; Simson, PG; Webster, A; Weiss, JM, 1986) |
| "Both paroxetine and pargyline were effective in reducing the immobility time of stressed OVX mice in the FST." | 1.38 | Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system. ( Bazanella Sampaio, T; Mozzaquatro Gai, B; Nogueira, CW; Pinton, S; Trevisan da Rocha, J; Zeni, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (87.50) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trevisan da Rocha, J | 1 |
| Mozzaquatro Gai, B | 1 |
| Pinton, S | 1 |
| Bazanella Sampaio, T | 1 |
| Nogueira, CW | 1 |
| Zeni, G | 1 |
| OLTMAN, JE | 1 |
| FRIEDMAN, S | 1 |
| SIEGLER, PE | 1 |
| KLINE, NS | 1 |
| MCCURDY, RL | 1 |
| KAN, FJ | 1 |
| TURNER, WJ | 1 |
| MERLIS, S | 1 |
| BLACKWELL, B | 1 |
| MABBITT, LA | 1 |
| JACOBS, MA | 1 |
| PILLARD, R | 1 |
| Ashmarin, IP | 2 |
| Danilova, RA | 2 |
| Obukhova, MF | 2 |
| Belopol'skaia, MV | 1 |
| Moskvityna, TA | 1 |
| Belopolskaya, MV | 1 |
| Lynch, MA | 1 |
| Leonard, BE | 1 |
| Slater, SL | 1 |
| Lipper, S | 5 |
| Shiling, DJ | 2 |
| Murphy, DL | 5 |
| Slater, S | 2 |
| Buchsbaum, MS | 1 |
| Nies, AS | 1 |
| Lerner, P | 1 |
| Major, LF | 1 |
| Lake, CR | 1 |
| Lovenberg, W | 1 |
| Campbell, IC | 1 |
| Major, LJ | 1 |
| Gordon, E | 1 |
| Weiss, JM | 2 |
| Simson, PG | 2 |
| Ambrose, MJ | 1 |
| Webster, A | 1 |
| McNair, DM | 1 |
| Wyatt, RJ | 1 |
| Kupfer, DJ | 1 |
| Scott, J | 1 |
| Robinson, DS | 1 |
| Snyder, F | 1 |
| Plotnikoff, NP | 1 |
| Kastin, AJ | 1 |
| Anderson, MS | 1 |
| Schally, AV | 1 |
| Matussek, N | 1 |
| Iriye, TT | 1 |
| Simmonds, FA | 1 |
2 reviews available for pargyline and Depression
| Article | Year |
|---|---|
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classif | 1964 |
Self-evaluations of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipr | 1974 |
4 trials available for pargyline and Depression
| Article | Year |
|---|---|
Elevation of plasma-prolactin by monoamine-oxidase inhibitors.
Topics: Clorgyline; Depression; Female; Humans; Hydrocortisone; Male; Pargyline; Placebos; Prolactin; Propyl | 1977 |
Comparative behavioral effects of clorgyline and pargyline in man: a preliminary evaluation.
Topics: Clinical Trials as Topic; Clorgyline; Depression; Double-Blind Method; Female; Humans; Male; Pargyli | 1979 |
Self-evaluations of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipr | 1974 |
Clinical and animal experiments concerning the function of brain catecholamines.
Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Ca | 1971 |
19 other studies available for pargyline and Depression
| Article | Year |
|---|---|
Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system.
Topics: Animals; Antidepressive Agents; Benzene Derivatives; Cerebral Cortex; Depression; Disease Models, An | 2012 |
PARGYLINE IN THE TREATMENT OF DEPRESSIVE ILLNESSES.
Topics: Antidepressive Agents; Antihypertensive Agents; Depression; Depressive Disorder; Hypotension; Imipra | 1963 |
THE PRACTICAL MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Antidepressive Agents; Benzoates; Classification; Depression; Depressive Disorder; Dr | 1964 |
TRANSIENT BRAIN SYNDROME AS A NON-FATAL REACTION TO COMBINED PARGYLINE-IMIPRAMINE TREATMENT.
Topics: Brain; Depression; Depressive Disorder; Drug Therapy; Geriatrics; Hypertension; Imipramine; Mental D | 1964 |
A CLINICAL TRIAL OF PARGYLINE AND DOPA IN PSYCHOTIC SUBJECTS.
Topics: Adolescent; Biomedical Research; Brain; Brain Damage, Chronic; Depression; Depressive Disorder, Majo | 1964 |
TYRAMINE IN CHEESE RELATED TO HYPERTENSIVE CRISES AFTER MONOAMINE-OXIDASE INHIBITION.
Topics: Cheese; Chromatography; Colorimetry; Depression; Depressive Disorder; Drug Therapy; Electrophoresis; | 1965 |
APPROACH TO STUDYING DRUG EFFECTS IN AMBULATORY PATIENTS.
Topics: Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Pargyline; Placebos; Psychologic | 1965 |
[Induction of long-term depression (with anxiety and fear components) by immunization of rats against pargyline].
Topics: Animals; Anxiety; Depression; Fear; Male; Monoamine Oxidase Inhibitors; Pargyline; Rats; Rats, Wista | 1998 |
Pargyline conjugate-induced long-term activation of monoamine oxidase as an immunological model for depression.
Topics: Animals; Behavior, Animal; Depression; Enzyme Activation; Male; Models, Biological; Monoamine Oxidas | 1999 |
Effect of chronic amphetamine administration on the behaviour of rats in the open field apparatus: reversal of post-withdrawal depression by two antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Dextroamphetamine; Huma | 1978 |
Adverse reactions and interactions limiting the use of antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Depression; Dose-Response Relationship, Drug; Drug Interact | 1975 |
Dopamine-beta-hydroxylase and norepinephrine in human cerebrospinal fluid: effects of monoamine oxidase inhibitors.
Topics: Clorgyline; Depression; Depression, Chemical; Dopamine beta-Hydroxylase; Humans; Monoamine Oxidase I | 1979 |
A biochemical measure of monoamine oxidase type A and B inhibitor effects in man.
Topics: Animals; Blood Platelets; Brain; Clorgyline; Culture Techniques; Depression; Dose-Response Relations | 1979 |
Effects of clorgyline and pargyline on deaminated metabolites of norepinephrine, dopamine and serotonin in human cerebrospinal fluid.
Topics: Clorgyline; Depression; Dopamine; Homovanillic Acid; Humans; Norepinephrine; Pargyline; Propylamines | 1979 |
Depression in an animal model: focus on the locus ceruleus.
Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Clonidine; Depression; Electroshock; Locus Co | 1986 |
Infusion of a monoamine oxidase inhibitor into the locus coeruleus can prevent stress-induced behavioral depression.
Topics: Animals; Depression; Electroshock; Locus Coeruleus; Male; Norepinephrine; Pargyline; Rats; Stress, P | 1986 |
Longitudinal studies of the effect of monoamine oxidase inhibitors on sleep in man.
Topics: Blood Platelets; Depression; Female; Humans; Hydrazines; Isocarboxazid; Isoniazid; Male; Monoamine O | 1969 |
Deserpidine antagonism by a tripeptide, L-prolyl-L-leucyglycinamide.
Topics: Animals; Depression; Dihydroxyphenylalanine; Disease Models, Animal; Dose-Response Relationship, Dru | 1973 |
Possible involvement of glycogen phosphorylase of brain in the affective states.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorpromazine; Depression; Desipramine; Drug In | 1971 |