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guanethidine and Depression

guanethidine has been researched along with Depression in 17 studies

Guanethidine: An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
guanethidine : A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
guanethidine sulfate : A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" Other reported effects are toxic confusional states and psychotic reactions."2.36Psychiatric side effects of antihypertensive drugs other than reserpine. ( Fleminger, R; Paykel, ES; Watson, JP, 1982)
" The following considerations regarding tricyclic antidepressant therapy are discussed: dosage schedules, onset of action, anticholinergic effects, cardiac toxicity and drug interactions."1.25Rational use of psychotropic drugs. IV. Antidepressants. ( Greenblatt, DJ; Shader, RI, 1975)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199017 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BEWLEY, TH1
MEIRING, PD1
Paykel, ES1
Fleminger, R1
Watson, JP1
Ghose, K1
Coppen, A1
Turner, P2
Nies, AS1
Burgess, CD1
Wadsworth, J1
Poe, TE1
Edwards, JL1
Taylor, RB1
Sandifer, MG1
Zweifler, AJ1
Esler, M1
Greenblatt, DJ1
Shader, RI1
Davis, JM1
Bant, W1
Snaith, RP1
McCoubrie, M1
Raisfeld, IH1
Meyer, JF1
McAllister, CK1
Goldberg, LI1
Gerson, IM1
Friedman, R1
Unterberger, H1

Reviews

2 reviews available for guanethidine and Depression

ArticleYear
Psychiatric side effects of antihypertensive drugs other than reserpine.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin;

1982
Cardiovascular complications of antidepressant therapy. Interactions at the adrenergic neuron.
    American heart journal, 1972, Volume: 83, Issue:1

    Topics: Antidepressive Agents; Cardiovascular Diseases; Depression; Drug Interactions; Electrocardiography;

1972

Trials

2 trials available for guanethidine and Depression

ArticleYear
Autonomic actions and interactions of mianserin hydrochloride (Org. GB 94) and amitriptyline in patients with depressive illness.
    Psychopharmacology, 1976, Sep-17, Volume: 49, Issue:2

    Topics: Amitriptyline; Autonomic Nervous System; Blood Pressure; Clinical Trials as Topic; Depression; Diben

1976
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular

1978

Other Studies

13 other studies available for guanethidine and Depression

ArticleYear
TO-DAY'S DRUGS. BETHANIDINE SULPHATE.
    British medical journal, 1964, Oct-03, Volume: 2, Issue:5413

    Topics: Antihypertensive Agents; Bethanidine; Bretylium Compounds; Chemistry, Pharmaceutical; Depression; De

1964
EXPERIENCES WITH THE LONG-TERM USE OF METHYLDOPA ("ALDOMET") IN HYPERTENSION.
    The Medical journal of Australia, 1965, Mar-20, Volume: 1, Issue:12

    Topics: Benzothiadiazines; Blood Pressure Determination; Depression; Drug Therapy; Drug Tolerance; Glomerulo

1965
Adverse reactions and interactions limiting the use of antihypertensive drugs.
    The American journal of medicine, 1975, Volume: 58, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Depression; Dose-Response Relationship, Drug; Drug Interact

1975
Hypertensive crisis possibly due to drug interaction.
    Postgraduate medicine, 1979, Volume: 66, Issue:5

    Topics: Blood Pressure; Chlorpromazine; Depression; Doxepin; Drug Interactions; Guanethidine; Humans; Hypert

1979
The hypertensive psychiatric patient: pharmacologic problems.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:9

    Topics: Antihypertensive Agents; Clonidine; Depression; Diuretics; Drug Interactions; Guanethidine; Humans;

1978
Drugs for hypertension.
    The Medical letter on drugs and therapeutics, 1977, Mar-11, Volume: 19, Issue:5

    Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Depression; Diuretics; Drug Combinations; Dru

1977
Factors influencing the choice of antihypertensive agents.
    Postgraduate medicine, 1976, Volume: 60, Issue:7

    Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications;

1976
Rational use of psychotropic drugs. IV. Antidepressants.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:1

    Topics: Antidepressive Agents; Depression; Drug Interactions; Guanethidine; Heart Diseases; Humans; Intestin

1975
Psychopharmacology in the aged. Use of psychotropic drugs in geriatric patients.
    Journal of geriatric psychiatry, 1974, Volume: 7, Issue:2

    Topics: Aged; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Depression; Dih

1974
Do antihypertensive drugs really cause depression?
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:9

    Topics: Acute Disease; Antihypertensive Agents; Chronic Disease; Depression; Guanethidine; Humans; Hypertens

1974
Antihypertensive drugs and depression.
    Psychological medicine, 1974, Volume: 4, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Bethanidine; Chlorthalidone; Depression; Diuretics; Drug Thera

1974
Insidious and prolonged antagonism of guanethidine by amitriptyline.
    JAMA, 1970, Aug-31, Volume: 213, Issue:9

    Topics: Amitriptyline; Blood Pressure; Depression; Guanethidine; Humans; Hypertension; Male; Middle Aged

1970
Non-antagonism of antiadrenergic agents by a dibenzoxepine. (Preliminary report).
    Diseases of the nervous system, 1970, Volume: 31, Issue:11

    Topics: Aged; Blood Pressure; Depression; Dibenzothiazepines; Electrocardiography; Female; Guanethidine; Hum

1970