vorinostat has been researched along with Depression in 4 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Depression is a disabling psychiatric disorder affecting millions of people all around the world." | 1.62 | SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class. ( Amini-Khoei, H; Dehpour, AR; Ershadi, ASB; Hosseini, MJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ershadi, ASB | 1 |
| Amini-Khoei, H | 1 |
| Hosseini, MJ | 1 |
| Dehpour, AR | 1 |
| Chen, WY | 1 |
| Zhang, H | 1 |
| Gatta, E | 1 |
| Glover, EJ | 1 |
| Pandey, SC | 1 |
| Lasek, AW | 1 |
| Covington, HE | 1 |
| Maze, I | 1 |
| LaPlant, QC | 1 |
| Vialou, VF | 1 |
| Ohnishi, YN | 1 |
| Berton, O | 1 |
| Fass, DM | 1 |
| Renthal, W | 1 |
| Rush, AJ | 1 |
| Wu, EY | 1 |
| Ghose, S | 1 |
| Krishnan, V | 1 |
| Russo, SJ | 1 |
| Tamminga, C | 1 |
| Haggarty, SJ | 1 |
| Nestler, EJ | 1 |
| Uchida, S | 1 |
| Hara, K | 1 |
| Kobayashi, A | 1 |
| Otsuki, K | 1 |
| Yamagata, H | 1 |
| Hobara, T | 1 |
| Suzuki, T | 1 |
| Miyata, N | 1 |
| Watanabe, Y | 1 |
4 other studies available for vorinostat and Depression
| Article | Year |
|---|---|
SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cognitive Dysfunction; Depression; Female; Fluoxet | 2021 |
The histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) alleviates depression-like behavior and normalizes epigenetic changes in the hippocampus during ethanol withdrawal.
Topics: Acetylation; Animals; Depression; Epigenesis, Genetic; Hippocampus; Histone Deacetylase 2; Histone D | 2019 |
Antidepressant actions of histone deacetylase inhibitors.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Depression; Dise | 2009 |
Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events.
Topics: Adaptation, Biological; Animals; Basal Ganglia; Behavior, Animal; Depression; DNA Methylation; Epige | 2011 |