gallic acid has been researched along with Depression in 12 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current study evaluates the free gallic acid (GA) and GA-loaded mesoporous silica nanoparticles (MSNs) antidepressant efficacy in a rat model of depression caused by reserpine." | 8.12 | Evaluation of the therapeutic effect of mesoporous silica nanoparticles loaded with Gallic acid on reserpine-induced depression in Wistar rats. ( Ahmed, NA; Fahmy, HM; Hussein, AA; Khadrawy, YA; Mohamed, ER, 2022) |
| "Administration of leonurine (60 mg/kg) for 4 weeks significantly alleviated depression-like behaviors of chronic mild stress mice, including increased sucrose preference and reduced immobility time in forced swimming test and tail suspension test." | 7.85 | Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation. ( Chen, M; Ding, J; Ding, X; Du, R; Hu, G; Jia, M; Li, C; Lu, M; Zheng, Y, 2017) |
| "Administration of leonurine (60 mg/kg) for 4 weeks significantly alleviated depression-like behaviors of chronic mild stress mice, including increased sucrose preference and reduced immobility time in forced swimming test and tail suspension test." | 3.85 | Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation. ( Chen, M; Ding, J; Ding, X; Du, R; Hu, G; Jia, M; Li, C; Lu, M; Zheng, Y, 2017) |
| "Depression is a disorder with a high incidence that has been increasing worldwide although the pathophysiology remains unclear." | 1.46 | Morus nigra and its major phenolic, syringic acid, have antidepressant-like and neuroprotective effects in mice. ( Camargo, A; Dalmagro, AP; Zeni, ALB, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fahmy, HM | 1 |
| Mohamed, ER | 1 |
| Hussein, AA | 1 |
| Khadrawy, YA | 1 |
| Ahmed, NA | 1 |
| Yang, R | 1 |
| Shi, L | 1 |
| Si, H | 1 |
| Hu, Z | 1 |
| Zou, L | 1 |
| Li, L | 1 |
| Xu, X | 1 |
| Schmalzing, G | 1 |
| Nie, H | 1 |
| Li, G | 1 |
| Liu, S | 1 |
| Liang, S | 1 |
| Xu, C | 1 |
| Dalmagro, AP | 2 |
| Camargo, A | 2 |
| Pedron, NB | 1 |
| Garcia, SAM | 1 |
| Zeni, ALB | 2 |
| Can, ÖD | 1 |
| Turan, N | 1 |
| Demir Özkay, Ü | 1 |
| Öztürk, Y | 1 |
| Jia, M | 1 |
| Li, C | 1 |
| Zheng, Y | 1 |
| Ding, X | 1 |
| Chen, M | 1 |
| Ding, J | 1 |
| Du, R | 1 |
| Lu, M | 1 |
| Hu, G | 1 |
| Pereira, MM | 1 |
| de Morais, H | 1 |
| Dos Santos Silva, E | 1 |
| Corso, CR | 1 |
| Adami, ER | 1 |
| Carlos, RM | 1 |
| Acco, A | 1 |
| Zanoveli, JM | 1 |
| Samad, N | 1 |
| Jabeen, S | 1 |
| Imran, I | 1 |
| Zulfiqar, I | 1 |
| Bilal, K | 1 |
| Nabavi, SF | 1 |
| Habtemariam, S | 1 |
| Di Lorenzo, A | 1 |
| Sureda, A | 1 |
| Khanjani, S | 1 |
| Nabavi, SM | 1 |
| Daglia, M | 1 |
| Chhillar, R | 1 |
| Dhingra, D | 1 |
| Galeotti, N | 1 |
| Bartolini, A | 1 |
| Ghelardini, C | 1 |
| Angrist, B | 1 |
| Park, S | 1 |
| Urcuyo, L | 1 |
| Roffman, M | 1 |
| Gershon, S | 1 |
1 trial available for gallic acid and Depression
| Article | Year |
|---|---|
Clinical evaluation of a possible catechol-O-methyl transferase inhibitor in endogenous depression.
Topics: Catechol O-Methyltransferase Inhibitors; Catechols; Clinical Trials as Topic; Depression; Evaluation | 1973 |
11 other studies available for gallic acid and Depression
| Article | Year |
|---|---|
Evaluation of the therapeutic effect of mesoporous silica nanoparticles loaded with Gallic acid on reserpine-induced depression in Wistar rats.
Topics: Animals; Depression; Dopamine; Gallic Acid; Nanoparticles; Norepinephrine; Rats; Rats, Wistar; Reser | 2022 |
Gallic Acid Improves Comorbid Chronic Pain and Depression Behaviors by Inhibiting P2X7 Receptor-Mediated Ferroptosis in the Spinal Cord of Rats.
Topics: Animals; Chronic Pain; Comorbidity; Depression; Ferroptosis; Gallic Acid; Neuralgia; Rats; Rats, Spr | 2023 |
Morus nigra leaves extract revokes the depressive-like behavior, oxidative stress, and hippocampal damage induced by corticosterone: a pivotal role of the phenolic syringic acid.
Topics: Animals; Antioxidants; Behavior, Animal; Cell Survival; Corticosterone; Depression; Fluoxetine; Gall | 2020 |
Morus nigra and its major phenolic, syringic acid, have antidepressant-like and neuroprotective effects in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Gallic Acid; Lipid Peroxidation | 2017 |
Antidepressant-like effect of gallic acid in mice: Dual involvement of serotonergic and catecholaminergic systems.
Topics: Animals; Antidepressive Agents; Catecholamines; Depression; Disease Models, Animal; Dose-Response Re | 2017 |
Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation.
Topics: Animals; Antidepressive Agents; Calcium-Binding Proteins; Cytokines; Depression; Disease Models, Ani | 2017 |
The antioxidant gallic acid induces anxiolytic-, but not antidepressant-like effect, in streptozotocin-induced diabetes.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Anxiety; Behavior, Animal; Depres | 2018 |
Protective effect of gallic acid against arsenic-induced anxiety-/depression- like behaviors and memory impairment in male rats.
Topics: Animals; Anxiety; Arsenic; Behavior, Animal; Brain; Depression; Gallic Acid; Lipid Peroxidation; Mal | 2019 |
Post-Stroke Depression Modulation and in Vivo Antioxidant Activity of Gallic Acid and Its Synthetic Derivatives in a Murine Model System.
Topics: Animals; Antioxidants; Depression; Gallic Acid; Humans; Injections, Intraperitoneal; Male; Mice; Mic | 2016 |
Antidepressant-like activity of gallic acid in mice subjected to unpredictable chronic mild stress.
Topics: Animals; Antidepressive Agents; Antioxidants; Brain; Catalase; Corticosterone; Depression; Fluoxetin | 2013 |
Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Calcium; Calcium Channel Blo | 2006 |