silybin has been researched along with Depression in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, W; Fujisaki, H; Hattori, S; Hayashi, T; Ikejima, T; Liu, W; Liu, X; Mizuno, K; Wang, C | 1 |
| Heidari-Soureshjani, S; Rostamian, S; Sherwin, CMT | 1 |
| Cui, L; Hattori, S; Hayashi, T; Ikejima, T; Liu, B; Liu, W; Song, X; Tashiro, SI; Ushiki-Kaku, Y; Xu, F; Zhou, B | 1 |
| Li, YJ; Niu, WM; Wei, XM; Wu, YM; Yang, LD; Yang, Q; Zhang, K; Zhao, MG; Zheng, KY | 1 |
| Bertino, G; Caraci, F; Chisari, G; Drago, F; Greco, C; Malaguarnera, G; Malaguarnera, M; Motta, M; Nunnari, G; Vacante, M; Vecchio, M | 1 |
1 review(s) available for silybin and Depression
| Article | Year |
|---|---|
The Therapeutic Effect of Silymarin and Silibinin on Depression and Anxiety Disorders and Possible Mechanism in the Brain: A Systematic Review.
Topics: Antioxidants; Anxiety Disorders; Depression; Glutathione; Hippocampus; Humans; Silybin; Silymarin | 2023 |
1 trial(s) available for silybin and Depression
| Article | Year |
|---|---|
Silybin supplementation during HCV therapy with pegylated interferon-α plus ribavirin reduces depression and anxiety and increases work ability.
Topics: Adult; Antioxidants; Antiviral Agents; Anxiety; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Psychiatric Status Rating Scales; Ribavirin; Silybin; Silymarin; Treatment Outcome; Work Performance | 2016 |
3 other study(ies) available for silybin and Depression
| Article | Year |
|---|---|
Silibinin ameliorates depression/anxiety-like behaviors of Parkinson's disease mouse model and is associated with attenuated STING-IRF3-IFN-β pathway activation and neuroinflammation.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anxiety; Depression; Disease Models, Animal; Humans; Interferon Regulatory Factor-3; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Quality of Life; Silybin | 2021 |
Silibinin ameliorates anxiety/depression-like behaviors in amyloid β-treated rats by upregulating BDNF/TrkB pathway and attenuating autophagy in hippocampus.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anxiety; Autophagy; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Hippocampus; Indans; Male; Neurons; Neuroprotective Agents; Peptide Fragments; Piperidines; Psychotropic Drugs; Rats, Sprague-Dawley; Receptor, trkB; Signal Transduction; Silybin; Silymarin; Up-Regulation | 2017 |
Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disease Models, Animal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Silybin; Silymarin; Stress, Psychological | 2018 |