perphenazine has been researched along with Depression in 76 studies
Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.
perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
Excerpt | Relevance | Reference |
---|---|---|
"Patients with DSM-IV-defined schizophrenia (N = 1,460) were assigned to treatment with a first-generation antipsychotic (perphenazine) or one of 4 second-generation drugs (olanzapine, quetiapine, risperidone, or ziprasidone) and followed for up to 18 months (phase 1)." | 9.15 | Impact of second-generation antipsychotics and perphenazine on depressive symptoms in a randomized trial of treatment for chronic schizophrenia. ( Addington, DE; Davis, SM; Lieberman, JA; McEvoy, JP; Mohamed, S; Rosenheck, RA; Stroup, TS; Swartz, MS, 2011) |
" We report a case of recurrent priapism that was treated with Fluoxetine and low dose Perphenazine." | 7.74 | Treatment of idiopathic recurrent priapism with fluoxetine and low dose Perphenazine. ( Ahmadi, A; Khazaie, H; Moradi, M; Tahmasian, M, 2008) |
"Patients with DSM-IV-defined schizophrenia (N = 1,460) were assigned to treatment with a first-generation antipsychotic (perphenazine) or one of 4 second-generation drugs (olanzapine, quetiapine, risperidone, or ziprasidone) and followed for up to 18 months (phase 1)." | 5.15 | Impact of second-generation antipsychotics and perphenazine on depressive symptoms in a randomized trial of treatment for chronic schizophrenia. ( Addington, DE; Davis, SM; Lieberman, JA; McEvoy, JP; Mohamed, S; Rosenheck, RA; Stroup, TS; Swartz, MS, 2011) |
" We report a case of recurrent priapism that was treated with Fluoxetine and low dose Perphenazine." | 3.74 | Treatment of idiopathic recurrent priapism with fluoxetine and low dose Perphenazine. ( Ahmadi, A; Khazaie, H; Moradi, M; Tahmasian, M, 2008) |
"Hiccup is a spasmodic, involuntary contraction of the inspiratory muscles, associated with delayed and abrupt glottic closure causing a peculiar sound (Launois et al." | 1.30 | Perphenazine-induced hiccups. ( Kamijima, K; Miyaoka, H, 1999) |
"Dental Caries are an uncommon, but significant side effect of the tricyclic antidepressants and other anticholinergic psychoactive drugs." | 1.26 | Rampant dental caries in the treatment of depression. ( Bassuk, E; Schoonover, S, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 72 (94.74) | 18.7374 |
1990's | 1 (1.32) | 18.2507 |
2000's | 2 (2.63) | 29.6817 |
2010's | 1 (1.32) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Khazaie, H | 1 |
Moradi, M | 1 |
Tahmasian, M | 1 |
Ahmadi, A | 1 |
Addington, DE | 1 |
Mohamed, S | 1 |
Rosenheck, RA | 1 |
Davis, SM | 1 |
Stroup, TS | 1 |
McEvoy, JP | 1 |
Swartz, MS | 1 |
Lieberman, JA | 1 |
MATTEY, WE | 1 |
NAHUNEK, K | 3 |
GREENFIELD, AR | 2 |
RONDEPIERRE, JJ | 1 |
ROPERT, R | 2 |
BOEGNER-PLICHET, M | 1 |
PIRET, J | 1 |
GARRABE, J | 1 |
PEYROUZET, JM | 1 |
ERNST, EM | 1 |
MCLAUGHLIN, BE | 2 |
RYAN, F | 1 |
DRUCKER, T | 1 |
STORROW, HA | 1 |
PENNINGTON, VM | 1 |
FORREST, FM | 1 |
GEITER, CW | 1 |
SNOW, HL | 1 |
STEINBACH, M | 1 |
KRIS, EB | 1 |
GERST, D | 1 |
COFFEE, HL | 1 |
ITIL, TM | 1 |
HINTON, JM | 1 |
Chacón, C | 1 |
Downham, ET | 1 |
Hope-Simpson, RE | 1 |
Todd, JP | 1 |
Davis, WG | 1 |
Bourgeois, M | 1 |
Miyaoka, H | 1 |
Kamijima, K | 1 |
Meyers, BS | 1 |
Klimstra, SA | 1 |
Gabriele, M | 1 |
Hamilton, M | 1 |
Kakuma, T | 1 |
Tirumalasetti, F | 1 |
Alexopoulos, GS | 1 |
Nelson, JC | 1 |
Bowers, MB | 1 |
Diamond, S | 2 |
Prusoff, BA | 2 |
Williams, DH | 2 |
Weissman, MM | 2 |
Astrachan, BM | 2 |
Huapaya, LV | 1 |
Sherwin, D | 1 |
Loeb, C | 1 |
Roccatagliatà, G | 1 |
Besio, G | 1 |
Bassuk, E | 1 |
Schoonover, S | 1 |
Kamen, S | 1 |
Woodward, JA | 1 |
Henry, BW | 1 |
Overall, JE | 4 |
Hollister, LE | 4 |
Falk, MA | 1 |
Rickels, K | 1 |
Hutchison, JC | 1 |
Weise, CC | 2 |
Csanalosi, I | 1 |
Chung, HR | 1 |
Case, WG | 1 |
Anderson, J | 1 |
Lambert, NG | 1 |
Pigott, PV | 2 |
O'Reilly, PP | 1 |
Hesbacher, P | 1 |
Haskell, DS | 1 |
McNair, DM | 1 |
Fisher, S | 1 |
Kahn, RJ | 1 |
Palem, RM | 1 |
Johnson, MH | 2 |
Downing, RW | 1 |
Morris, JB | 1 |
Beck, AT | 1 |
Shelton, J | 3 |
Pennington, V | 1 |
Kimbell, I | 3 |
Johnson, M | 1 |
Loprete, FP | 1 |
Palm, C | 1 |
Browne, MW | 2 |
Baltes, BJ | 1 |
Hussain, Z | 1 |
Malitz, S | 1 |
Kanzler, M | 1 |
Martins, JK | 1 |
Lytton, GJ | 1 |
St-Jean, A | 1 |
Ban, TA | 1 |
Scott, J | 1 |
Goldstein, BJ | 1 |
Pinosky, DG | 1 |
Chateau, R | 1 |
Barron, CN | 1 |
Murchison, TE | 1 |
Rubin, LF | 1 |
Rubin, ML | 1 |
Herron, W | 1 |
Muscarella, M | 1 |
Birkhead, H | 1 |
Uno, M | 1 |
Invernizzi, G | 1 |
Sostero, M | 1 |
Vitali, A | 1 |
Campanella, F | 1 |
Podobnikar, IG | 1 |
Haider, I | 1 |
Cook, RW | 1 |
Núnek, K | 1 |
Mouren, P | 1 |
Giudicelli, S | 1 |
Scarrone, JJ | 1 |
D'omezon, G | 1 |
Gomez, JR | 1 |
Gomez, G | 1 |
Molcan, J | 1 |
Belanská, M | 1 |
Motýlová, A | 1 |
Wolf, M | 1 |
Polák, L | 1 |
Brunse, A | 1 |
Dorfman, W | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparative Effectiveness of Antipsychotic Medications in Patients With Schizophrenia (CATIE Schizophrenia Trial)[NCT00014001] | Phase 4 | 1,600 participants | Interventional | 2000-12-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
28 trials available for perphenazine and Depression
Article | Year |
---|---|
Impact of second-generation antipsychotics and perphenazine on depressive symptoms in a randomized trial of treatment for chronic schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chronic Disease; Comorbidity; Depression; Depressive | 2011 |
Treatment of anxiety and depression. A double-blind study of a perphenazine and amitriptyline in combination.
Topics: Adult; Aged; Amitriptyline; Anxiety; Depression; Female; Humans; Male; Middle Aged; Perphenazine | 1967 |
Continuation treatment of delusional depression in older adults.
Topics: Aged; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Combined Modality Therapy; Delusions; | 2001 |
Psychogenic headaches with mixed anxiety and depression.
Topics: Adolescent; Adult; Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Dextropropoxyphene; | 1975 |
A controlled clinical trial of amitriptyline added to perphenazine in the treatment of depressed schizophrenics [proceedings].
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Therapy, Combination; | 1979 |
Treatment of secondary depression in schizophrenia. A double-blind, placebo-controlled trial of amitriptyline added to perphenazine.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Amitriptyline; Blood Pressure; Body Weight; Chronic Diseas | 1979 |
The computer analyzes two psychotherapeutic agents in anxiety-depressed states.
Topics: Adolescent; Adult; Aged; Amitriptyline; Analysis of Variance; Anxiety; Chlorpromazine; Clinical Tria | 1973 |
Doxepin and amitriptyline-perphenazine in mixed anxious-depressed neurotic outpatients: a collaborative controlled study.
Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depression; Dibenzoxepins; Drug C | 1972 |
An evaluation of fluphenazine with nortriptyline in anxiety and depression.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Drug Combinations; Fluphenazine; Human | 1972 |
Perphenazine-amitriptyline in neurotic underachieving students: a controlled study.
Topics: Amitriptyline; Anxiety Disorders; Child; Clinical Trials as Topic; Depression; Evaluation Studies as | 1972 |
A review of clinical studies with combinations of fluphenazine and nortriptyline.
Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxe | 1972 |
A controlled outpatient trial of perphenazine--amitriptyline and chlorpromazine.
Topics: Adolescent; Adult; Amitriptyline; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; Dru | 1974 |
Drug therapy of depression. Amitriptyline, perphenazine, and their combination in different syndromes.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Drug Synergism; Humans; Male; Midd | 1967 |
Sleep in psychotic patients: a comparative clinical study.
Topics: Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depression; Humans; Hypnotics and Sedati | 1967 |
Therapy for psychotic and psychoneurotic depression with thiothixene and perphenazine-amitriptyline (a double-blind clinical study).
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Drug Synergism; Factor Analysis, Statistical; H | 1969 |
A comparison of two drug treatments in depressive illness.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Male; Midd | 1969 |
The office treatment of mixed anxiety and depression with combination therapy.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Family Practice; Humans; Perphenazine; | 1969 |
Drugs in depressive illness.
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Factor Analysis, Statistical; Humans; Perphenaz | 1970 |
Antidepressant effects of tranquillizers.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Amitriptyline; Child; Chlordiazepoxide; Clinical Tria | 1971 |
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as | 1971 |
Combined amitriptyline-perphenazine (Etrafon) compared with chlordiazepoxide hydrochloride: a double-blind, crossover study.
Topics: Adolescent; Adult; Aged; Amitriptyline; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depress | 1966 |
The effect of a protriptyline-perphenazine combination in chronic psychiatric patients.
Topics: Adolescent; Adult; Amitriptyline; Clinical Trials as Topic; Depression; Female; Humans; Intellectual | 1966 |
Clinical evaluation of doxepin in anxious depressed outpatients.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depression; Dibenzoxepins; Humans; Perphenazine; Psy | 1969 |
Triavil and Etrafon.
Topics: Amitriptyline; Chlordiazepoxide; Clinical Trials as Topic; Depression; Diazepam; Female; Humans; Mep | 1966 |
Treatment of mixed states of anxiety and depression.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Humans; Perphenazine | 1966 |
Amitriptyline and perphenazine in depressive illness. A controlled trial.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Drug Synergism; Female; Humans; Ma | 1967 |
Etrafon: a three year study.
Topics: Amitriptyline; Clinical Trials as Topic; Depression; Female; Humans; Male; Perphenazine | 1967 |
The treatment of anxiety and depression in general practice using an amitriptyline-perphenazine preparation.
Topics: Adult; Aged; Amitriptyline; Anxiety; Depression; Family Practice; Female; Humans; Male; Middle Aged; | 1968 |
48 other studies available for perphenazine and Depression
Article | Year |
---|---|
Treatment of idiopathic recurrent priapism with fluoxetine and low dose Perphenazine.
Topics: Adult; Antipsychotic Agents; Anxiety; Depression; Fluoxetine; Humans; Male; Perphenazine; Priapism; | 2008 |
Combination therapy for relief of anxiety and depression.
Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Perphena | 1963 |
[The treatment of endogenous depression with perphenazine and trihexyphenidyl. Relation to extrapyramidal symptomatology].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Extrapyramidal Tracts; Humans; Mental Disorders; | 1962 |
Control of alcoholic agitation and depression with perphenazine and amitriptyline combined.
Topics: Alcoholism; Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Humans; Perphenaz | 1963 |
[Perphenazine, piperazine phenothiazine in psychiatric therapy].
Topics: Depression; Humans; Mental Disorders; Neurologic Manifestations; Neurotic Disorders; Perphenazine; P | 1963 |
ANXIETY AND DEPRESSION: TREATMENT IN GENERAL PRACTICE.
Topics: Amitriptyline; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Family Practice; Female; | 1963 |
CONTROL OF ALCOHOLIC AGITATION AND DEPRESSION.
Topics: Alcoholism; Amitriptyline; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Perp | 1963 |
CLINICAL TRIALS WITH AMITRIPTYLINE AND PERPHENAZINE AMONG PSYCHIATRIC OUTPATIENTS.
Topics: Amitriptyline; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Outpatients; Per | 1964 |
DEPRESSION MASQUERADING AS APATHY.
Topics: Amitriptyline; Apathy; Depression; Depressive Disorder; Electronarcosis; Humans; Imipramine; Perphen | 1964 |
THE PHRENOTROPIC ACTION OF PERPHENAZINE-AMITRIPTYLINE.
Topics: Amitriptyline; Anxiety; Biomedical Research; Depression; Depressive Disorder; Drug Combinations; Hum | 1964 |
DRUG MAINTENANCE PROBLEMS OF REHABILITATED MENTAL PATIENTS: THE CURRENT DRUG DOSAGE "MERRY-GO-ROUND".
Topics: Chlordiazepoxide; Chlorpromazine; Depression; Imipramine; Mental Disorders; Mentally Ill Persons; Pe | 1964 |
COMBINED PERPHENAZINE-AMITRIPTYLINE AS ADJUVANT THERAPY IN PSYCHIATRIC AFTERCARE.
Topics: Aftercare; Amitriptyline; Depression; Depressive Disorder; Drug Combinations; Drug Therapy; Humans; | 1964 |
COMBINED AMITRIPTYLINE AND PERPHENAZINE IN COMBINED DEPRESSION AND ANXIETY.
Topics: Amitriptyline; Anxiety; Depression; Depressive Disorder; Drug Therapy; Humans; Perphenazine; Toxicol | 1964 |
PENTOTHAL INDUCED CHANGES IN EEG AS A PROGNOSTIC INDEX IN DRUGS THERAPY OF PSYCHOTIC PATIENTS.
Topics: Chlorpromazine; Depression; Drug Therapy; Electroencephalography; Mental Disorders; Neurotic Disorde | 1965 |
A comparison of perphenazine, ('fentazin') sodium amylobarbitone and a placebo in anxious and depressed out-patients.
Topics: Amobarbital; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Humans; Outpatients; Perph | 1959 |
[Clinical experiences with Perphenazine and Trihexyphenidyl in endogenous depression].
Topics: Depression; Depressive Disorder; Perphenazine; Trihexyphenidyl | 1962 |
[On the use of perphenazine in melancholic depression].
Topics: Depression; Depressive Disorder; Perphenazine | 1961 |
Amitriptyline and amitriptyline-with-perphenazine in depression--a retrospective study.
Topics: Amitriptyline; Depression; Drug Synergism; Female; Humans; Male; Perphenazine; Retrospective Studies | 1967 |
Herpes zoster in the elderly.
Topics: Adolescent; Adult; Aged; Child; Depression; Facial Paralysis; Herpes Zoster; Humans; Middle Aged; Pa | 1967 |
An unusual case of depression.
Topics: Adult; Amitriptyline; Anxiety; Depression; Female; Humans; Perphenazine; Tranquilizing Agents | 1967 |
[Study of an antidepressive agent in psychiatry: Mutabon F].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Amitriptyline; Anxiety Disorders; Bipolar Disorder; D | 1967 |
Perphenazine-induced hiccups.
Topics: Adult; Anxiety; Depression; Dopamine Antagonists; Hiccup; Humans; Male; Perphenazine | 1999 |
Delusional unipolar depression: description and drug response.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Delusions; Depression; Fema | 1978 |
Seven cases of somnambulism induced by drugs.
Topics: Adult; Alcoholism; Amitriptyline; Chlorprothixene; Depression; Drug Therapy, Combination; Ethchlorvy | 1979 |
A new method for treating "headaches".
Topics: Adult; Amitriptyline; Benztropine; Depression; Drug Therapy, Combination; Female; Follow-Up Studies; | 1979 |
[Variations in the urinary level of MHPG in depressive syndromes].
Topics: Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Anxiety; Depression; Depressive Disorder | 1979 |
Rampant dental caries in the treatment of depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Dental Caries; Depression; Drug Combinations | 1978 |
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive | 1975 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipra | 1975 |
Clinical differences among phenothiazines in schizophrenics. Introduction: specific indications for antipsychotics: elusive end of the rainbow.
Topics: Antipsychotic Agents; Depression; Haloperidol; Humans; Kinetics; Perphenazine; Phenothiazines; Piper | 1974 |
[Clinical study, in ambulatory treatment, of the amitriptyline-perphenazine association].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Ambulatory Care; Amitriptyline; Anxiety; Depression; | 1972 |
Pharmacotherapy of depression.
Topics: Antidepressive Agents; Depression; Humans; Hypnotics and Sedatives; Lithium; Perphenazine; Psychothe | 1973 |
Mixed anxiety-depression. Fact or myth?
Topics: Adult; Amitriptyline; Anxiety Disorders; Barbiturates; Chlordiazepoxide; Depression; Doxepin; Female | 1974 |
The efficacy of antidepressant drugs. A review of research (1958-1972).
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depression; Dibenza | 1974 |
Therapy for mild depressive and anxiety states.
Topics: Adolescent; Adult; Amitriptyline; Anxiety; Child; Depression; Female; Humans; Male; Middle Aged; Per | 1966 |
Etrafon, perphenazine-amitriptyline hydrochloride: a tranquilizer-antidepressant for oral administration.
Topics: Amitriptyline; Anxiety; Depression; Humans; Perphenazine | 1967 |
[Trial treatment of reactive and neurotic depressions with an association of amitriptyline and perphenazine].
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Depression; Drug Combinations; Female; Humans; Mal | 1972 |
Chlorpromazine and the eye of the dog. VI. A comparison of phenothiazine tranquilizers.
Topics: Administration, Oral; Animals; Chlorpromazine; Cornea; Corneal Opacity; Cytoplasmic Granules; Depres | 1972 |
[Follow-up studies of schizophrenia].
Topics: Adult; Catalepsy; Catatonia; Chlorpromazine; Chronic Disease; Convulsive Therapy; Depersonalization; | 1971 |
[Pharmacologic combinations in the therapy of depression: experiences with Mutabon (perphenazine and amitriptyline)].
Topics: Adult; Amitriptyline; Analysis of Variance; Depression; Drug Combinations; Evaluation Studies as Top | 1971 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; F | 1970 |
[Use in general and psychosomatic medicine of 2 associations with mixed, anti-depressive and tranquilizing action (amitriptyline + perphenazine)].
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Perphenazine; Psychophysiologic Disorders; | 1970 |
[Therapeutic trial of Mutanxion and Mutaspline in psychiatry].
Topics: Adult; Amitriptyline; Anxiety; Depression; Humans; Middle Aged; Perphenazine | 1971 |
[Pharmacotherapy of mental disorders with a combination of amitriptyline and perphenazine].
Topics: Adult; Amitriptyline; Depression; Drug Synergism; Female; Humans; Male; Perphenazine; Psychiatric St | 1968 |
Extrinsic factors influencing responses to psychotherapeutic drugs.
Topics: Adult; Amitriptyline; Analysis of Variance; Black or African American; Chlorpromazine; Depression; D | 1969 |
Amitryptiline alone and combined with perphenazine in newly admitted depressed patients.
Topics: Amitriptyline; Depression; Humans; Male; Perphenazine; Psychological Tests | 1966 |
Combined use of an anti-depressant with tranquilizer in the management of depression.
Topics: Amitriptyline; Anxiety; Bipolar Disorder; Depression; Drug Synergism; Electroconvulsive Therapy; Hum | 1966 |
Amitriptyline + perphenazine in depressive illness--a preliminary report.
Topics: Amitriptyline; Depression; Humans; Perphenazine | 1966 |