lactic acid has been researched along with Depression in 20 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The response to treatment with imipramine or clonazepam was evaluated in patients with panic disorder." | 7.68 | [Treatment of patients with panic disorder and an elevated urinary excretion of MHPG using imipramine or clonazepam]. ( Carreira, I; Casique, M; Lima, L; Morales, M; Silva, C, 1992) |
| "The purpose of this study is to explore depression metabolic markers in rat hippocampus and to investigate the anti-depressant effect of genipin and its mechanisms using nuclear magnetic resonance (NMR) metabonomics." | 3.80 | [1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. ( Gao, S; Peng, GJ; Qin, XM; Shi, BY; Tian, JS, 2014) |
| "The response to treatment with imipramine or clonazepam was evaluated in patients with panic disorder." | 3.68 | [Treatment of patients with panic disorder and an elevated urinary excretion of MHPG using imipramine or clonazepam]. ( Carreira, I; Casique, M; Lima, L; Morales, M; Silva, C, 1992) |
| "Status epilepticus was evoked in half of the sedentary and trained rats by a repetitive intraperitoneal injection of KA in low subconvulsive doses." | 1.46 | Effect of Training at Lactate Threshold Intensity on Maximal Time to Exhaustion, Depression and Anxiety Behaviour of Spontaneously Hypertensive Rats after Kainate-Induced Status Epilepticus. ( Andreev, GG; Georgiev, NG; Georgieva, KN; Hadjieva, MS; Shishmanova-Doseva, MS; Tchekalarova, JD; Terzieva, DD, 2017) |
| "Pain is often associated with depression of behavior and mood, and relief of pain-related depression is a common goal of treatment." | 1.40 | Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids. ( Banks, ML; Bowers, MS; Carlezon, WA; Cheng, K; Leitl, MD; Negus, SS; Onvani, S; Rice, KC, 2014) |
| "Pain is associated with stimulation of some behaviors (eg, withdrawal reflexes) but depression of many other behaviors (eg, feeding, locomotion, positively reinforced operant behavior)." | 1.39 | Effects of monoamine reuptake inhibitors in assays of acute pain-stimulated and pain-depressed behavior in rats. ( Carroll, FI; Negus, SS; Rosenberg, MB, 2013) |
| "Both lactic acid and morphine were equipotent in the stretching and ICSS procedures." | 1.35 | Effects of pain- and analgesia-related manipulations on intracranial self-stimulation in rats: further studies on pain-depressed behavior. ( Carlezon, WA; Negus, SS; Pereira Do Carmo, G; Stevenson, GW, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ouyang, X | 1 |
| Wang, Z | 1 |
| Luo, M | 1 |
| Wang, M | 1 |
| Liu, X | 1 |
| Chen, J | 1 |
| Feng, J | 1 |
| Jia, J | 1 |
| Wang, X | 1 |
| Pu, J | 1 |
| Liu, Y | 1 |
| Gui, S | 1 |
| Tian, L | 1 |
| Yu, Y | 1 |
| Wang, D | 1 |
| Zhong, X | 1 |
| Chen, W | 1 |
| Chen, X | 2 |
| Chen, Y | 1 |
| Gong, X | 1 |
| Liu, L | 1 |
| Li, W | 1 |
| Wang, H | 1 |
| Xie, P | 1 |
| Carrard, A | 2 |
| Cassé, F | 1 |
| Carron, C | 1 |
| Burlet-Godinot, S | 1 |
| Toni, N | 1 |
| Magistretti, PJ | 2 |
| Martin, JL | 2 |
| Georgieva, KN | 1 |
| Hadjieva, MS | 1 |
| Shishmanova-Doseva, MS | 1 |
| Terzieva, DD | 1 |
| Georgiev, NG | 1 |
| Andreev, GG | 1 |
| Tchekalarova, JD | 1 |
| Lazenka, MF | 1 |
| Freitas, KC | 1 |
| Henck, S | 1 |
| Negus, SS | 5 |
| Ribeiro, MC | 1 |
| Bezerra, TDS | 1 |
| Soares, AC | 1 |
| Boechat-Ramos, R | 1 |
| Carneiro, FP | 1 |
| Vianna, LMS | 1 |
| Faro, LRF | 1 |
| Silva, MVD | 1 |
| Vieira, MP | 1 |
| Monteiro, IO | 1 |
| Ferreira, VM | 1 |
| Karnib, N | 1 |
| El-Ghandour, R | 1 |
| El Hayek, L | 1 |
| Nasrallah, P | 1 |
| Khalifeh, M | 1 |
| Barmo, N | 1 |
| Jabre, V | 1 |
| Ibrahim, P | 1 |
| Bilen, M | 1 |
| Stephan, JS | 1 |
| Holson, EB | 1 |
| Ratan, RR | 1 |
| Sleiman, SF | 1 |
| Chester, AL | 1 |
| Edwards, AM | 1 |
| Crowe, M | 1 |
| Quirk, F | 1 |
| Leitl, MD | 1 |
| Onvani, S | 1 |
| Bowers, MS | 1 |
| Cheng, K | 1 |
| Rice, KC | 1 |
| Carlezon, WA | 2 |
| Banks, ML | 1 |
| Kwilasz, AJ | 1 |
| Abdullah, RA | 1 |
| Poklis, JL | 1 |
| Lichtman, AH | 1 |
| Peng, GJ | 1 |
| Shi, BY | 1 |
| Tian, JS | 1 |
| Gao, S | 1 |
| Qin, XM | 1 |
| Detka, J | 1 |
| Kurek, A | 1 |
| Kucharczyk, M | 1 |
| Głombik, K | 1 |
| Basta-Kaim, A | 1 |
| Kubera, M | 1 |
| Lasoń, W | 1 |
| Budziszewska, B | 1 |
| Elsayed, M | 1 |
| Margineanu, M | 1 |
| Boury-Jamot, B | 1 |
| Fragnière, L | 1 |
| Meylan, EM | 1 |
| Petit, JM | 1 |
| Fiumelli, H | 1 |
| Ong, J | 1 |
| Clarke, A | 1 |
| White, P | 1 |
| Johnson, MA | 1 |
| Withey, S | 1 |
| Butler, PE | 1 |
| Pereira Do Carmo, G | 1 |
| Stevenson, GW | 1 |
| Donath, L | 1 |
| Boettger, S | 1 |
| Puta, C | 1 |
| Wetzig, F | 1 |
| Mueller, HJ | 1 |
| Bär, KJ | 1 |
| Gabriel, HH | 1 |
| LOWENBACH, H | 1 |
| GREENHILL, MH | 1 |
| Rosenberg, MB | 1 |
| Carroll, FI | 1 |
| Morrison, JL | 1 |
| Chien, C | 1 |
| Riggs, KW | 1 |
| Gruber, N | 1 |
| Rurak, D | 1 |
| Lima, L | 1 |
| Carreira, I | 1 |
| Morales, M | 1 |
| Silva, C | 1 |
| Casique, M | 1 |
1 trial available for lactic acid and Depression
| Article | Year |
|---|---|
Dissociation of performance parameters at the IAT requires specific exercise recommendations for depressed patients.
Topics: Adult; Anaerobic Threshold; Analysis of Variance; Bicycling; Depression; Exercise; Exercise Test; Fe | 2010 |
19 other studies available for lactic acid and Depression
| Article | Year |
|---|---|
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Topics: Animals; Behavior, Animal; Cell Line; Depression; Glucose; Glucose Transporter Type 3; Ketamine; Lac | 2021 |
Effects of pharmacological treatment on metabolomic alterations in animal models of depression.
Topics: Animals; Depression; Glucose; Inositol; Kynurenine; Lactic Acid; Models, Animal; Serotonin; Tryptoph | 2022 |
Role of adult hippocampal neurogenesis in the antidepressant actions of lactate.
Topics: Animals; Antidepressive Agents; Depression; Hippocampus; Lactic Acid; Neurogenesis; Neuronal Plastic | 2021 |
Effect of Training at Lactate Threshold Intensity on Maximal Time to Exhaustion, Depression and Anxiety Behaviour of Spontaneously Hypertensive Rats after Kainate-Induced Status Epilepticus.
Topics: Animals; Anxiety; Behavior, Animal; Comorbidity; Depression; Disease Models, Animal; Essential Hyper | 2017 |
Relief of Pain-Depressed Behavior in Rats by Activation of D1-Like Dopamine Receptors.
Topics: Analgesics; Animals; Behavior, Animal; Benzazepines; Conditioning, Operant; Depression; Dopamine Ago | 2017 |
Hippocampal and cerebellar histological changes and their behavioural repercussions caused by brain ischaemic hypoxia experimentally induced by sodium nitrite.
Topics: Animals; Anxiety; Blood Glucose; Brain Ischemia; Cerebellum; Cholesterol; Depression; Hippocampus; H | 2017 |
Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases.
Topics: Animals; Antidepressive Agents; Anxiety; Avoidance Learning; Behavior, Animal; Benzamides; Depressio | 2019 |
Physiological, biochemical, and psychological responses to environmental survival training in the Royal Australian Air Force.
Topics: Adult; Aerospace Medicine; Affect; Anxiety; Australia; Body Weight; Creatine Kinase; Depression; Fem | 2013 |
Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Depression; Disease Models, Animal; Dopamine; Gene E | 2014 |
Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats.
Topics: Amidohydrolases; Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Benzamides; Brain; Carbam | 2014 |
[1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus].
Topics: Alanine; Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Chronic Disease; Depressio | 2014 |
Brain glucose metabolism in an animal model of depression.
Topics: Administration, Oral; Animals; Brain; Depression; Disease Models, Animal; Female; Glucose; Glucoseph | 2015 |
Peripheral administration of lactate produces antidepressant-like effects.
Topics: Animals; Antidepressive Agents; Astrocytes; Depression; Depressive Disorder, Major; Disease Models, | 2018 |
Objective evidence for the use of polylactic acid implants in HIV-associated facial lipoatrophy using three-dimensional surface laser scanning and psychological assessment.
Topics: Adult; Aged; Anxiety; Body Image; Cheek; Depression; Esthetics; Face; Follow-Up Studies; HIV-Associa | 2009 |
Effects of pain- and analgesia-related manipulations on intracranial self-stimulation in rats: further studies on pain-depressed behavior.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Biophysics; Conditioning, Opera | 2009 |
The effect of oral administration of lactic acid upon the clinical course of depressive states.
Topics: Administration, Oral; Bipolar Disorder; Depression; Depressive Disorder; Humans; Lactic Acid; Mental | 1947 |
Effects of monoamine reuptake inhibitors in assays of acute pain-stimulated and pain-depressed behavior in rats.
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Biophysics; Conditioning, Operant; Depression; | 2013 |
Effect of maternal fluoxetine administration on uterine blood flow, fetal blood gas status, and growth.
Topics: Acid-Base Equilibrium; Animals; Antidepressive Agents, Second-Generation; Blood Gas Analysis; Blood | 2002 |
[Treatment of patients with panic disorder and an elevated urinary excretion of MHPG using imipramine or clonazepam].
Topics: Adult; Anxiety Disorders; Clonazepam; Depression; Female; Humans; Imipramine; Lactates; Lactic Acid; | 1992 |