Page last updated: 2024-10-16

carbamates and Depression

carbamates has been researched along with Depression in 40 studies

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to determine the involvement of the endocannabinoid system in anxiety- and depression-related behaviors in methamphetamine-withdrawal male NMRI mice."4.02URB597 abrogates anxiogenic and depressive behaviors in the methamphetamine-withdrawal mice: Role of the cannabinoid receptor type 1, cannabinoid receptor type 2, and transient receptor potential vanilloid 1 channels. ( Ebrahimi-Ghiri, M; Khakpai, F; Zarrindast, MR, 2021)
"In all subjects, SJW had no effect on the total area under the plasma concentration-time curve from time zero to infinity (AUC(∞)), the peak plasma concentration (C(max)) or the elimination half-life (t(½)) of repaglinide."2.76The pregnane X receptor agonist St John's Wort has no effects on the pharmacokinetics and pharmacodynamics of repaglinide. ( Chen, WQ; Fan, L; Guo, D; Liu, YL; Liu, ZQ; Sheng, D; Tan, ZR; Zhang, W; Zhou, G; Zhou, HH, 2011)
"While insulin resistance is common in older people, large numbers also have impaired insulin secretion."2.40The elderly Type 2 diabetic patient: special considerations. ( Morley, JE, 1998)
"Neuropathic pain is often associated with depression."1.51Inhibition of Fatty Acid Amide Hydrolase Improves Depressive-Like Behaviors Independent of Its Peripheral Antinociceptive Effects in a Rat Model of Neuropathic Pain. ( Gong, DY; Hai, KR; Jiang, HX; Ke, BW; Liu, J; Ma, G; Yang, Z; Zhou, C, 2019)
"Posttraumatic stress disorder (PTSD) is a debilitating condition highly comorbid with depression."1.48Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD. ( Akirav, I; Burstein, O; Doron, R; Shoshan, N, 2018)
"Remarkably, the long-lasting widespread hyperalgesia induced by combining CUS and NGF was effectively reduced by URB597, but not by JZL184."1.42Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic pain. ( Bindila, L; Hoheisel, U; Lerner, R; Lomazzo, E; Lutz, B; Remmers, F; Schwitter, C, 2015)
"05-10 μg/mouse) produced antidepressant-like effect dose-dependently, whereas influenced the MBB in a biphasic manner (produced a U-shaped dose-response curve)."1.37Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. ( Jain, NS; Manna, SS; Umathe, SN, 2011)
"Treatments in Alzheimer's disease include treatment of cognitive impairment and behavioral manifestations (agitation, depression, anxiety, delusions)."1.30[Drug therapy strategies in Alzheimer's disease]. ( Lacomblez, L, 1998)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199017 (42.50)18.7374
1990's2 (5.00)18.2507
2000's5 (12.50)29.6817
2010's11 (27.50)24.3611
2020's5 (12.50)2.80

Authors

AuthorsStudies
Krystal, AD1
Benca, RM1
Rosenberg, R1
Schweitzer, PK1
Malhotra, A1
Babson, K1
Lee, L1
Bujanover, S1
Strohl, KP1
Maymon, N1
Mizrachi Zer-Aviv, T2
Sabban, EL1
Akirav, I3
Dong, B1
Shilpa, BM1
Shah, R1
Goyal, A1
Xie, S1
Bakalian, MJ1
Suckow, RF1
Cooper, TB1
Mann, JJ1
Arango, V1
Vinod, KY1
Alteba, S1
Tenenhaus, A1
Ben David, G1
Adelman, J1
Hillard, CJ1
Doron, R2
Ebrahimi-Ghiri, M1
Khakpai, F1
Zarrindast, MR1
Wei, H1
Zhou, T1
Tan, B1
Zhang, L2
Li, M1
Xiao, Z1
Xu, F1
Burstein, O1
Shoshan, N1
Jiang, HX1
Ke, BW1
Liu, J1
Ma, G1
Hai, KR1
Gong, DY1
Yang, Z1
Zhou, C1
de Morais, H1
Chaves, YC1
Waltrick, APF1
Jesus, CHA1
Genaro, K1
Crippa, JA1
da Cunha, JM1
Zanoveli, JM1
Cuccurazzu, B1
Zamberletti, E2
Nazzaro, C1
Prini, P1
Trusel, M1
Grilli, M1
Parolaro, D1
Tonini, R1
Rubino, T2
Kwilasz, AJ1
Abdullah, RA1
Poklis, JL1
Lichtman, AH2
Negus, SS1
Meng, WQ1
Lu, L1
Xue, YS1
Li, C1
Zou, F1
Liu, Y1
Zhao, J1
Lomazzo, E1
Bindila, L1
Remmers, F1
Lerner, R1
Schwitter, C1
Hoheisel, U1
Lutz, B1
Simonnet, A1
Cador, M1
Caillé, S1
Adamczyk, P1
Gołda, A1
McCreary, AC1
Filip, M1
Przegaliński, E1
Umathe, SN1
Manna, SS1
Jain, NS1
Fan, L1
Zhou, G1
Guo, D1
Liu, YL1
Chen, WQ1
Liu, ZQ1
Tan, ZR1
Sheng, D1
Zhou, HH1
Zhang, W1
ANTON, A1
DONNADIEU, JM1
BRADITCH, JL1
DARBELLAY, J1
CHESROW, EJ1
KAPLITZ, SE1
SABATINI, R1
VETRA, H1
MARQUARDT, GH1
Piomelli, D1
Tarzia, G1
Duranti, A1
Tontini, A1
Mor, M1
Compton, TR1
Dasse, O1
Monaghan, EP1
Parrott, JA1
Putman, D1
Naidu, PS1
Varvel, SA1
Ahn, K1
Cravatt, BF1
Martin, BR1
Trenité, DG1
French, JA1
Hirsch, E1
Macher, JP1
Meyer, BU1
Grosse, PA1
Abou-Khalil, BW1
Rosenfeld, WE1
van Gerven, J1
Novak, GP1
Parmeggiani, L1
Schmidt, B1
Gibson, D1
Guerrini, R1
McLaughlin, RJ1
Hill, MN1
Morrish, AC1
Gorzalka, BB1
Spry, WB1
Lacomblez, L1
Morley, JE1
Cesa-Bianchi, M1
Ghirardi, P1
Ravaccia, F1
Kissin, B1
Gross, MM1
de Oliveira, JM1
Lehmann, HE1
Ban, TA1
Bratfos, O1
Lingjaerde, O1
Salvesen, C1
Rickels, K2
Hesbacher, P1
Vandervort, W1
Phillips, F1
Hutchison, J1
Sablosky, L1
Lavan, D1
Hesbacher, PT1
Weise, CC1
Gray, B1
Feldman, HS1
Meshel, E1
Denber, HC1
Majeron, MA1
Toselli, E1
Solaro, F1
Corletto, F1
Coppen, A1

Reviews

3 reviews available for carbamates and Depression

ArticleYear
Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597).
    CNS drug reviews, 2006,Spring, Volume: 12, Issue:1

    Topics: Amidohydrolases; Analgesics; Animals; Anxiety; Benzamides; Brain; Cannabinoids; Carbamates; Depressi

2006
The elderly Type 2 diabetic patient: special considerations.
    Diabetic medicine : a journal of the British Diabetic Association, 1998, Volume: 15 Suppl 4

    Topics: Aged; Amyloid; Blood Glucose; Carbamates; Cognition Disorders; Depression; Diabetes Mellitus, Type 2

1998
Pharmacotherapy of tension and anxiety.
    Current psychiatric therapies, 1972, Volume: 12

    Topics: Anxiety; Automobile Driving; Carbamates; Cerebral Cortex; Clinical Trials as Topic; Depression; Dibe

1972

Trials

9 trials available for carbamates and Depression

ArticleYear
Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression.
    Journal of psychiatric research, 2022, Volume: 155

    Topics: Carbamates; Depression; Disorders of Excessive Somnolence; Double-Blind Method; Humans; Narcolepsy;

2022
The pregnane X receptor agonist St John's Wort has no effects on the pharmacokinetics and pharmacodynamics of repaglinide.
    Clinical pharmacokinetics, 2011, Volume: 50, Issue:9

    Topics: Carbamates; Cross-Over Studies; Cytochrome P-450 Enzyme System; Depression; Genotype; Herb-Drug Inte

2011
Evaluation of carisbamate, a novel antiepileptic drug, in photosensitive patients: an exploratory, placebo-controlled study.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Adolescent; Adult; Affect; Anticonvulsants; Carbamates; Depression; Dose-Response Relationship, Drug

2007
A preliminary double-blind study with SB 5833 (camazepam), a new benzodiazepine derivative.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Carbamates; Clinical Trials as Topic; Depression; Dia

1974
Pharmacotherapy of tension and anxiety.
    Current psychiatric therapies, 1972, Volume: 12

    Topics: Anxiety; Automobile Driving; Carbamates; Cerebral Cortex; Clinical Trials as Topic; Depression; Dibe

1972
Symptomatic relief of neurotic symptoms with tybamate: a doube-blind, placebo-controlled study.
    Acta psychiatrica Scandinavica, 1967, Volume: 43, Issue:3

    Topics: Adult; Aged; Anxiety; Carbamates; Clinical Trials as Topic; Depression; Female; Humans; Hysteria; Ma

1967
Tybamate--a perplexing drug.
    The American journal of psychiatry, 1968, Volume: 125, Issue:3

    Topics: Adult; Anxiety Disorders; Carbamates; Clinical Trials as Topic; Depression; Female; Humans; Middle A

1968
Pills and improvement: a study of placebo response in psychoneurotic outpatients.
    Psychopharmacologia, 1970, Volume: 16, Issue:4

    Topics: Adult; Amitriptyline; Anxiety Disorders; Carbamates; Clinical Trials as Topic; Depression; Family Pr

1970
Double-blind study of tybamate in psychotic patients.
    Diseases of the nervous system, 1967, Volume: 28, Issue:5

    Topics: Adult; Aged; Aggression; Anxiety; Carbamates; Clinical Trials as Topic; Depression; Female; Humans;

1967

Other Studies

29 other studies available for carbamates and Depression

ArticleYear
Neuropeptide Y and cannabinoids interaction in the amygdala after exposure to shock and reminders model of PTSD.
    Neuropharmacology, 2020, 01-01, Volume: 162

    Topics: Amygdala; Animals; Arachidonic Acids; Arousal; Basolateral Nuclear Complex; Behavior, Animal; Benzam

2020
Dual pharmacological inhibitor of endocannabinoid degrading enzymes reduces depressive-like behavior in female rats.
    Journal of psychiatric research, 2020, Volume: 120

    Topics: Amidohydrolases; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Carbamates; Depressio

2020
Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2020, Volume: 39

    Topics: Age Factors; Animals; Antidepressive Agents; Benzamides; Benzodioxoles; Carbamates; Depression; Fema

2020
URB597 abrogates anxiogenic and depressive behaviors in the methamphetamine-withdrawal mice: Role of the cannabinoid receptor type 1, cannabinoid receptor type 2, and transient receptor potential vanilloid 1 channels.
    Journal of psychopharmacology (Oxford, England), 2021, Volume: 35, Issue:7

    Topics: Amidohydrolases; Animals; Anxiety; Behavior, Animal; Benzamides; Cannabinoid Receptor Antagonists; C

2021
Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway.
    Oncotarget, 2017, Jul-04, Volume: 8, Issue:27

    Topics: Animals; Biosynthetic Pathways; Carbamates; Cell Line; Constitutive Androstane Receptor; Depression;

2017
Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 06-08, Volume: 84, Issue:Pt A

    Topics: Amidohydrolases; Animals; Benzamides; Benzoxazines; Brain-Derived Neurotrophic Factor; Cannabinoid R

2018
Inhibition of Fatty Acid Amide Hydrolase Improves Depressive-Like Behaviors Independent of Its Peripheral Antinociceptive Effects in a Rat Model of Neuropathic Pain.
    Anesthesia and analgesia, 2019, Volume: 129, Issue:2

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Behavior, Animal; Benzamides; Carbamates; Depression; D

2019
Sub-chronic treatment with cannabidiol but not with URB597 induced a mild antidepressant-like effect in diabetic rats.
    Neuroscience letters, 2018, 08-24, Volume: 682

    Topics: Animals; Antidepressive Agents; Benzamides; Cannabidiol; Carbamates; Depression; Diabetes Mellitus,

2018
Adult Cellular Neuroadaptations Induced by Adolescent THC Exposure in Female Rats Are Rescued by Enhancing Anandamide Signaling.
    The international journal of neuropsychopharmacology, 2018, 11-01, Volume: 21, Issue:11

    Topics: Adaptation, Psychological; Animals; Arachidonic Acids; Benzamides; Carbamates; Dentate Gyrus; Depres

2018
Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats.
    Behavioural pharmacology, 2014, Volume: 25, Issue:2

    Topics: Amidohydrolases; Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Benzamides; Brain; Carbam

2014
Selective detection of endogenous H₂S in living cells and the mouse hippocampus using a ratiometric fluorescent probe.
    Scientific reports, 2014, Jul-29, Volume: 4

    Topics: Animals; Carbamates; Cattle; Cystathionine beta-Synthase; Depression; Disease Models, Animal; Down-R

2014
Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic pain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:2

    Topics: Amidohydrolases; Analgesics, Non-Narcotic; Animals; Anxiety; Benzamides; Benzodioxoles; Brain; Carba

2015
Chronic FAAH inhibition during nicotine abstinence alters habenular CB1 receptor activity and precipitates depressive-like behaviors.
    Neuropharmacology, 2017, Volume: 113, Issue:Pt A

    Topics: Amidohydrolases; Animals; Benzamides; Carbamates; Depression; Habenula; Male; Nicotine; Rats; Rats,

2017
Activation of endocannabinoid transmission induces antidepressant-like effects in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:2

    Topics: Animals; Antidepressive Agents; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carb

2008
Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice.
    Behavioural brain research, 2011, Sep-30, Volume: 223, Issue:1

    Topics: Animals; Antidepressive Agents; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carb

2011
[Gamaquil (gamma-phenylpropylcarbamate) in neurological practice].
    Die Medizinische Welt, 1963, Mar-23, Volume: 12

    Topics: Anti-Anxiety Agents; Carbamates; Depression; Depressive Disorder; Muscular Diseases; Neurotic Disord

1963
[Trial use of cyclarbamate in obstetrics].
    Revue francaise de gynecologie et d'obstetrique, 1963, Volume: 58

    Topics: Carbamates; Depression; Depressive Disorder; Female; Humans; Hyperemesis Gravidarum; Muscle Relaxant

1963
[THE ORTHONEUROTIC EMYLCAMATE IN DAILY PRACTICE].
    Bruxelles medical, 1963, Oct-06, Volume: 43

    Topics: Alcoholism; Anxiety; Anxiety Disorders; Automobiles; Carbamates; Cats; Depression; Geriatrics; Mice;

1963
A NEW PSYCHOTHERAPEUTIC AGENT EFFECTIVE IN THE MANAGEMENT OF GERIATRIC ANXIETY, DEPRESSION AND BEHAVIORAL REACTIONS.
    Journal of the American Geriatrics Society, 1965, Volume: 13

    Topics: Anxiety; Anxiety Disorders; Biomedical Research; Brain; Brain Damage, Chronic; Carbamates; Depressio

1965
Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality.
    Psychopharmacology, 2007, Volume: 192, Issue:1

    Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Behavior, Animal; Benzamides; Cannabinoid Rece

2007
Local enhancement of cannabinoid CB1 receptor signalling in the dorsal hippocampus elicits an antidepressant-like effect.
    Behavioural pharmacology, 2007, Volume: 18, Issue:5-6

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Cannabinoid Rece

2007
Tybamate.
    British medical journal, 1967, Jan-28, Volume: 1, Issue:5534

    Topics: Anxiety; Carbamates; Depression; Humans; Tranquilizing Agents

1967
Tybamate: a new tranquillizer.
    The British journal of clinical practice, 1967, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Anxiety; Carbamates; Depression; Female; Humans; Male; Middle Aged; Tranquilizing

1967
[Drug therapy strategies in Alzheimer's disease].
    La Revue du praticien, 1998, Nov-01, Volume: 48, Issue:17

    Topics: Aggression; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Car

1998
Drug therapy in alcoholism.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox

1970
[Effects of pyridinocarbamate in chronic cerebral arteriosclerosis].
    Hospital (Rio de Janeiro, Brazil), 1970, Volume: 77, Issue:2

    Topics: Aged; Carbamates; Depression; Female; Humans; Intracranial Arteriosclerosis; Male; Mental Fatigue; M

1970
[Clinical experience with a new tranquilizing agent: tybamate].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1969, Oct-31, Volume: 93, Issue:5

    Topics: Aging; Anxiety Disorders; Carbamates; Depression; Evaluation Studies as Topic; Humans; Psychotic Dis

1969
[Tybamate in the practice at geriatric outpatient clinics].
    Giornale di gerontologia, 1968, Volume: 16, Issue:1

    Topics: Aged; Anxiety; Brain Damage, Chronic; Carbamates; Depression; Female; Humans; Male; Middle Aged; Out

1968
Mineral metabolism in affective disorders.
    The British journal of psychiatry : the journal of mental science, 1965, Volume: 111, Issue:481

    Topics: Biological Transport; Blood-Brain Barrier; Bromine; Carbamates; Depression; Humans; Lithium; Potassi

1965