hydroxyurea has been researched along with Depression in 4 studies
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent studies demonstrated beneficial effects of zileuton, a 5-lipoxygenase (5LO) inhibitor, on some brain diseases in animal models, but the role of zileuton in the depression remains unknown." | 3.88 | Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice. ( Du, YF; Hong, H; Hu, M; Li, DD; Long, Y; Reed, MN; Suppiramaniam, V; Tang, SS; Xie, H, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCoy, B | 1 |
| Jaffe, RJ | 1 |
| Coffey, BJ | 1 |
| Li, DD | 1 |
| Xie, H | 1 |
| Du, YF | 1 |
| Long, Y | 1 |
| Reed, MN | 1 |
| Hu, M | 1 |
| Suppiramaniam, V | 1 |
| Hong, H | 1 |
| Tang, SS | 1 |
| Carmel, R | 1 |
| Bellevue, R | 1 |
| Kelman, Z | 1 |
| Cleaver, JE | 1 |
4 other studies available for hydroxyurea and Depression
| Article | Year |
|---|---|
Regaining Control: Anxiety in Sickle Cell Disease.
Topics: Adolescent; Anemia, Sickle Cell; Antidepressive Agents; Antisickling Agents; Anxiety Disorders; Chro | 2020 |
Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP; Dep | 2018 |
Low cobalamin levels associated with sickle cell disease: Contrasting origins and clinical meanings in two instructive patients.
Topics: Adult; Anemia, Pernicious; Anemia, Sickle Cell; Autoantibodies; Depression; Female; Folic Acid; Gast | 2010 |
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient; | 1969 |