Compounds > efavirenz

efavirenz and Depression

efavirenz has been researched along with Depression in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (17.86)29.6817
2010's17 (60.71)24.3611
2020's6 (21.43)2.80

Authors

AuthorsStudies
Han, J; Li, B; Liu, Y; Xiao, J; Zhang, L; Zhao, H1
Adimora, AA; Dastgheyb, R; Fischl, MA; Fitzgerald, KC; Gustafson, DR; Konkle-Parker, D; Li, Y; Maki, PM; Milam, J; Ofotokun, I; Rubin, LH; Sharma, A; Spence, AB; Weber, KM; Williams, DW; Xu, Y1
Arraes, LC; Brandão, LAC; Carvalho-Silva, WHV; Coelho, AVC; Crovella, S; Guimarães, RL; Moura, RR; Valeriano, JJLS1
Camacho, M; Castillo, A; Checa, A; Hernandez, I; Tapia, W; Teran, E1
Allen Reeves, A; Caballero, J; Fuentes, AV; Harrington, C; Mosley Ii, JF; Thomas, JE1
Bengtson, AM; Cole, SR; Collier, AC; Crane, HM; Eaton, EF; Edwards, JK; Mathews, WC; Mollan, KR; O'Cleirigh, C; Pence, BW; Tierney, C; Weideman, AMK; Westreich, D; Xu, S1
Eaton, EF; Gravett, RM; Mugavero, MJ; Tamhane, AR1
Abbasian, L; Ahmadi, M; Ghaeli, P; Khalili, H1
Bangsberg, DR; Boum, Y; Bwana, M; Chang, JL; Haberer, JE; Hunt, PW; Martin, JN; Musinguzi, N; Muzoora, C; Siedner, MJ; Tsai, AC1
Alcaide, ML; Jones, DL; Peltzer, K; Rodriguez, VJ; Weiss, SM1
Bangsberg, DR; Boum, Y; Bwana, B; Chang, JL; Haberer, JE; Hunt, PW; Kroetz, DL; Lee, SA; Martin, J; Musinguzi, N; Muzoora, C; Siedner, MJ; Tsai, AC1
Acurcio, FA; Bonolo, PF; Ceccato, MDGB; Costa, JO; Pearson, SA; Silveira, MR1
Becker, JT; Cheng, Y; Ho, K; Levine, A; Li, Y; Martin, E; Ragin, A; Rubin, LH; Sacktor, N; Wang, Z1
Akhondzadeh, S; Alimadadi, A; Dabaghzadeh, F; Ghaeli, P; Jafari, S; Khalili, H; Khazaeipour, Z1
Alvarez, D; Asensi, V; García, L; Gómez-Sirvent, J; Gutiérrez, F; Masiá, M; Moreno, S; Navarro, G; Padilla, S; Vidal, F1
Barenbaum, S; Chimbengo, G; Gross, R; Ngoni, T; Platoff, R; Rantleru, T; Ratshaa, B; Sonenthal, PD; Steenhoff, AP1
Grintjes-Huisman, K; Keuter, M; Koopmans, P; Mothapo, KM; Schellekens, A; van Crevel, R; van der Ven, A1
Katamba, A; Martin, F; Mwesigire, DM; Seeley, J; Wu, AW1
Gaida, R; Godman, B; Grobler, C; Kotze, T; Truter, I1
Felton-Coleman, A; Fletcher, CV; Owen, A; Podany, AT; Robertson, K; Sandkovsky, U; Swindells, S; Winchester, LC1
Cavalcante, GI; Chaves Filho, AJ; de Carvalho Lima, CN; de França Fonteles, MM; de Souza, FC; Linhares, MI; Macêdo, D; Rios, ER; Vasconcelos, SM; Venâncio, ET1
Casado, JL; Corral, I; Dronda, F; Hernández, B; Moreno, A; Moreno, S; Pérez-Elías, MJ; Quereda, C; Rodríguez-Sagrado, MA1
Chassany, O; Costagliola, D; Lavignon, M; Potard, V; Spire, B1
Aurpibul, L; Chotirosniramit, N; Kosashunhanan, N; Piyamongkol, W; Sugandhavesa, P; Supindham, T; Supparatpinyo, K; Thetket, S1
Carrieri, P; Garzot, MA; L'henaff, M; Obadia, Y; Spire, B1
Leonard, BE; Myint, AM; O'Mahony, SM; Steinbusch, H1
Boly, L; Cafaro, V; Dyner, T1
Delaporte, E; Girard, PM; Landman, R; Ndiaye, B; Ngom Gueye, NF; Poupard, M; Sow, PS; Thiam, D1

Reviews

2 review(s) available for efavirenz and Depression

ArticleYear
Neurotoxicities in the treatment of HIV between dolutegravir, rilpivirine and dolutegravir/rilpivirine: a meta-analysis.
    Sexually transmitted infections, 2021, Volume: 97, Issue:4

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Drug Combinations; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Neurotoxicity Syndromes; Oxazines; Piperazines; Pyridones; Randomized Controlled Trials as Topic; Rilpivirine

2021
A review of trials investigating efavirenz-induced neuropsychiatric side effects and the implications.
    Expert review of anti-infective therapy, 2016, Volume: 14, Issue:4

    Topics: Alkynes; Anti-HIV Agents; Anxiety; Benzoxazines; Cyclopropanes; Depression; Dizziness; HIV Infections; Humans; Sleep Wake Disorders

2016

Trials

4 trial(s) available for efavirenz and Depression

ArticleYear
Effect of Valerian in Preventing Neuropsychiatric Adverse Effects of Efavirenz in HIV-Positive Patients: A Pilot Randomized, Placebo-Controlled Clinical Trial.
    The Annals of pharmacotherapy, 2017, Volume: 51, Issue:6

    Topics: Adult; Alkynes; Anti-HIV Agents; Anxiety; Benzoxazines; Cyclopropanes; Depression; Double-Blind Method; Female; HIV Infections; Humans; Hypnotics and Sedatives; Male; Patient Compliance; Pilot Projects; Valerian

2017
Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial.
    AIDS patient care and STDs, 2013, Volume: 27, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; Cyproheptadine; Depression; Double-Blind Method; Female; HIV Infections; Humans; Iran; Male; Mental Disorders; Personality Inventory; Psychiatric Status Rating Scales; Serotonin Antagonists; Socioeconomic Factors; Suicidal Ideation; Surveys and Questionnaires; Treatment Outcome

2013
Improvement of Depression and Anxiety After Discontinuation of Long- Term Efavirenz Treatment.
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:6

    Topics: Adult; Alkynes; Anxiety; Benzoxazines; Cyclopropanes; Depression; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Reverse Transcriptase Inhibitors; Surveys and Questionnaires; Withholding Treatment; Young Adult

2015
Effect of treatment with efavirenz on neuropsychiatric adverse events of interferon in HIV/HCV-coinfected patients.
    Journal of acquired immune deficiency syndromes (1999), 2008, Sep-01, Volume: 49, Issue:1

    Topics: Alkynes; Anti-HIV Agents; Anxiety Disorders; Benzoxazines; Cyclopropanes; Depression; Drug Therapy, Combination; Female; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Male; Mental Disorders; Mood Disorders

2008

Other Studies

22 other study(ies) available for efavirenz and Depression

ArticleYear
Anxiety, depression, and sleep disturbances among people on long-term efavirenz-based treatment for HIV: a cross-sectional study in Beijing, China.
    BMC psychiatry, 2022, 11-16, Volume: 22, Issue:1

    Topics: Anxiety; Beijing; Cross-Sectional Studies; Depression; HIV Infections; Humans; Sleep; Sleep Wake Disorders

2022
Associations between Antiretroviral Drugs on Depressive Symptomatology in Homogenous Subgroups of Women with HIV.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2021, Volume: 16, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Depressive Disorder, Major; Diagnostic Self Evaluation; Female; Follow-Up Studies; HIV Infections; Humans; Middle Aged; Occupations; Patients; Prospective Studies; Psychology; Socioeconomic Factors; Surveys and Questionnaires; Symptom Assessment

2021
Increased risk of dizziness in human immunodeficiency virus-infected patients taking zidovudine and efavirenz combination: a Brazilian cohort study.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brazil; Cyclopropanes; Depression; Dizziness; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Middle Aged; Retrospective Studies; Reverse Transcriptase Inhibitors; Sleep Initiation and Maintenance Disorders; Survival Analysis; Time Factors; Zidovudine

2020
Depression is associated with efavirenz-containing treatments in newly antiretroviral therapy initiated HIV patients in Ecuador.
    AIDS research and therapy, 2020, 07-29, Volume: 17, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Ecuador; Female; HIV Infections; Humans; Male; Prospective Studies; Reverse Transcriptase Inhibitors; Young Adult

2020
Transportability From Randomized Trials to Clinical Care: On Initial HIV Treatment With Efavirenz and Suicidal Thoughts or Behaviors.
    American journal of epidemiology, 2021, 10-01, Volume: 190, Issue:10

    Topics: Adult; Alkynes; Anti-HIV Agents; Antidepressive Agents; Benzoxazines; Cyclopropanes; Depression; Drug Prescriptions; Female; HIV; HIV Infections; Humans; Incidence; Male; Observational Studies as Topic; Proportional Hazards Models; Randomized Controlled Trials as Topic; Suicidal Ideation; Translational Research, Biomedical; United States

2021
Antiretroviral Therapy Initiation and Changes in Self-Reported Depression.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Jun-15, Volume: 64, Issue:12

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Depression; Follow-Up Studies; HIV Infections; Humans; Insurance, Health; Logistic Models; Male; Middle Aged; Retrospective Studies; Self Report; Young Adult

2017
Depression and Suicidal Ideation Among HIV-Infected Adults Receiving Efavirenz Versus Nevirapine in Uganda: A Prospective Cohort Study.
    Annals of internal medicine, 2018, 08-07, Volume: 169, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Female; HIV Infections; Humans; Male; Nevirapine; Prospective Studies; Suicidal Ideation; Uganda

2018
The Use of Efavirenz During Pregnancy is Associated with Suicidal Ideation in Postpartum Women in Rural South Africa.
    AIDS and behavior, 2019, Volume: 23, Issue:1

    Topics: Adult; Alkynes; Benzoxazines; Contraindications, Drug; Cross-Sectional Studies; Cyclopropanes; Depression; Depression, Postpartum; Female; HIV Infections; Humans; Intimate Partner Violence; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Risk Factors; Rural Population; Social Stigma; South Africa; Suicidal Ideation; Surveys and Questionnaires; Young Adult

2019
CYP2B6 Genetic Polymorphisms, Depression, and Viral Suppression in Adults Living with HIV Initiating Efavirenz-Containing Antiretroviral Therapy Regimens in Uganda: Pooled Analysis of Two Prospective Studies.
    AIDS research and human retroviruses, 2018, Volume: 34, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2B6 Inducers; Depression; Female; Genotype; HIV; HIV Infections; Humans; Male; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Uganda; Viral Load

2018
Health-related quality of life among HIV-infected patients initiating treatment in Brazil in the single-tablet regimen era.
    AIDS care, 2019, Volume: 31, Issue:5

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Anxiety; Benzoxazines; Brazil; Cyclopropanes; Depression; Drug Combinations; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Oxazines; Piperazines; Pyridones; Quality of Life; Surveys and Questionnaires; Tablets

2019
Neuropsychological changes in efavirenz switch regimens.
    AIDS (London, England), 2019, 07-01, Volume: 33, Issue:8

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Depression; Drug Substitution; Female; HIV Infections; Humans; Male; Middle Aged; Neuropsychological Tests; Severity of Illness Index

2019
Risk of clinically significant depression in HIV-infected patients: effect of antiretroviral drugs.
    HIV medicine, 2014, Volume: 15, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Depression; Female; HIV Infections; Humans; Male; Middle Aged; Poisson Distribution; Prospective Studies; Reverse Transcriptase Inhibitors

2014
Baseline predictors of efavirenz-containing antiretroviral regimen adverse experiences.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:7

    Topics: Adult; Alcohol Drinking; Alkynes; Anti-HIV Agents; Benzoxazines; Body Weight; Botswana; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Depression; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors

2014
Quality of life in patients treated with first-line antiretroviral therapy containing nevirapine or efavirenz in Uganda: a prospective non-randomized study.
    BMC health services research, 2015, Jul-28, Volume: 15

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Depression; Female; HIV Infections; Humans; Interviews as Topic; Male; Mental Health; Nevirapine; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Treatment Outcome; Uganda; World Health Organization

2015
Impact of efavirenz pharmacokinetics and pharmacogenomics on neuropsychological performance in older HIV-infected patients.
    The Journal of antimicrobial chemotherapy, 2017, Volume: 72, Issue:1

    Topics: Aged; AIDS Dementia Complex; Alkynes; Anxiety; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Cytochrome P-450 CYP2B6; Depression; Female; HIV Infections; Humans; Male; Middle Aged; Neuropsychological Tests; Pharmacogenetics; Plasma; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Sleep Wake Disorders

2017
HIV antiretroviral drug Efavirenz induces anxiety-like and depression-like behavior in rats: evaluation of neurotransmitter alterations in the striatum.
    European journal of pharmacology, 2017, Mar-15, Volume: 799

    Topics: Alkynes; Animals; Anti-HIV Agents; Anxiety; Benzoxazines; Cyclopropanes; Depression; Male; Maze Learning; Neostriatum; Neurotransmitter Agents; Rats; Rats, Wistar; Time Factors

2017
Better health-related quality of life after switching from a virologically effective regimen to a regimen containing efavirenz or nevirapine.
    AIDS care, 2010, Volume: 22, Issue:1

    Topics: Adult; Aged; Alkynes; Anxiety; Benzoxazines; Cyclopropanes; Depression; Female; France; Health Status; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Surveys and Questionnaires; Treatment Outcome; Viral Load; Young Adult

2010
Correlation of CYP2B6-516G > T Polymorphism with Plasma Efavirenz Concentration and Depression in HIV-Infected Adults in Northern Thailand.
    Current HIV research, 2012, Volume: 10, Issue:8

    Topics: Adult; Alkynes; Alleles; Analysis of Variance; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Cytochrome P-450 CYP2B6; Depression; Female; Genotype; HIV Infections; Humans; Male; Middle Aged; Oxidoreductases, N-Demethylating; Polymorphism, Single Nucleotide; Reverse Transcriptase Inhibitors; Thailand

2012
Factors associated with efavirenz discontinuation in a large community-based sample of patients.
    AIDS care, 2004, Volume: 16, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cross-Sectional Studies; Cyclopropanes; Depression; Female; France; HIV Infections; Humans; Logistic Models; Male; Odds Ratio; Oxazines; Patient Acceptance of Health Care; Surveys and Questionnaires; Treatment Refusal

2004
Efavirenz induces depressive-like behaviour, increased stress response and changes in the immune response in rats.
    Neuroimmunomodulation, 2005, Volume: 12, Issue:5

    Topics: Alkynes; Animals; Anti-HIV Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Benzoxazines; Cyclopropanes; Cytokines; Depression; Enzyme-Linked Immunosorbent Assay; Interleukin-1; Male; Maze Learning; Oxazines; Paroxetine; Rats; Rats, Wistar; Stress, Psychological; Tumor Necrosis Factor-alpha

2005
Depressive symptoms predict increased incidence of neuropsychiatric side effects in patients treated with efavirenz.
    Journal of acquired immune deficiency syndromes (1999), 2006, Aug-01, Volume: 42, Issue:4

    Topics: Alkynes; Benzoxazines; Cyclopropanes; Depression; HIV Infections; Humans; Oxazines; Psychoses, Substance-Induced; Reverse Transcriptase Inhibitors

2006
Quality of life and depression among HIV-infected patients receiving efavirenz- or protease inhibitor-based therapy in Senegal.
    HIV medicine, 2007, Volume: 8, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Depression; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Quality of Life; Senegal; Sex Distribution; Sleep Wake Disorders

2007