Page last updated: 2024-11-12
myrsinoic acid b
Description
myrsinoic acid B: from Myrsine seguinii; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
myrsinoic acid B : A member of the class of 1-benzofurans that is 2,3-dihydro-1-benzofuran substituted by a carboxy group at position 5, a 1',5'-dimethyl-1'-hydroxy-4'-hexenyl group at position 2 and a prenyl group at position 7. Isolated from Myrsine seguinii, it exhibits anti-inflammatory activity. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|
| Myrsine | genus | A genus of flowering plants in the family PRIMULACEAE, found worldwide but primarily in tropical and subtropical regions.[MeSH] | Primulaceae | A plant family of the order ERICALES, class MAGNOLIOPSIDA, with flowers having both stamens and pistil, producing encapsulated fruits.[MeSH] |
| Myrsine seguinii | species | [no description available] | Primulaceae | A plant family of the order ERICALES, class MAGNOLIOPSIDA, with flowers having both stamens and pistil, producing encapsulated fruits.[MeSH] |
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 10383781 |
| CHEBI ID | 66427 |
| SCHEMBL ID | 13425367 |
| MeSH ID | M0442408 |
Synonyms (10)
| Synonym |
|---|
| ACON1_002027 |
| NCGC00179902-01 |
| BRD-A84851829-001-01-9 |
| myrsinoic acid b |
| 5-carboxy-2,3-dihydro-2-(1',5'-dimethyl-1'-hydroxy-4'-hexenyl)-7-(3''-methyl-2''-butenyl)benzofuran |
| 2-(2-hydroxy-6-methylhept-5-en-2-yl)-7-(3-methylbut-2-en-1-yl)-2,3-dihydro-1-benzofuran-5-carboxylic acid |
| CHEBI:66427 |
| SCHEMBL13425367 |
| 2-(2-hydroxy-6-methylhept-5-en-2-yl)-7-(3-methylbut-2-enyl)-2,3-dihydro-1-benzofuran-5-carboxylic acid |
| Q27134987 |
Research Excerpts
Overview
Myrsinoic acid B (MAB) is a diprenylated benzoic acid widely found in the vegetal kingdom.
| Excerpt | Reference | Relevance |
|---|
| "Myrsinoic acid B (AMB) is a prenylated-benzoic acid derivative isolated from the Rapanea genus. " | ( Assessment of mechanisms involved in antinociception caused by myrsinoic acid B.
de Souza, MM; Delle Monache, F; Hess, S; Holzmann, I; Malheiros, A; Padoani, C; Scorteganha, LC; Yunes, RA, 2010) | 2.04 |
| "Myrsinoic acid B (MAB) is a diprenylated benzoic acid widely found in the vegetal kingdom. " | ( Antihyperalgesic effects of myrsinoic acid B in pain-like behavior induced by inflammatory and neuropathic pain models in mice.
Antonialli, Cde S; da Silva, GF; de Souza, MM; Malheiros, A; Monteiro, ER; Quintão, NL; Rocha, LW; Yunes, RA, 2012) | 2.12 |
Roles (3)
| Role | Description |
|---|
| metabolite | Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| anti-inflammatory agent | Any compound that has anti-inflammatory effects. |
| EC 4.4.1.11 (methionine gamma-lyase) inhibitor | An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of the enzyme methionine gamma-lyase (EC 4.4.1.11). |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (2)
| Class | Description |
|---|
| 1-benzofurans | A member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof. |
| monocarboxylic acid | An oxoacid containing a single carboxy group. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.22
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.22 (24.57) | | Research Supply Index | 2.30 (2.92) | | Research Growth Index | 4.52 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |