guanfacine has been researched along with Depression in 4 studies
Guanfacine: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the study was to determine whether there are sex differences in the effect of guanfacine in tests of anxiolytic and antidepressant efficacy in mice at baseline and in a hypercholinergic model of depression induced by the acetylcholinesterase inhibitor physostigmine." | 3.81 | Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice. ( Bentham, MP; McKee, SA; Mineur, YS; Picciotto, MR; Plantenga, ME; Zhou, WL, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nikou, AF | 1 |
| Lai, M | 1 |
| Solmssen, C | 1 |
| Bhargava, M | 1 |
| Ben-David, K | 1 |
| Ramsubick, C | 1 |
| Rice, T | 1 |
| Coffey, B | 1 |
| Mineur, YS | 2 |
| Cahuzac, EL | 1 |
| Mose, TN | 1 |
| Bentham, MP | 2 |
| Plantenga, ME | 2 |
| Thompson, DC | 1 |
| Picciotto, MR | 2 |
| Zhou, WL | 1 |
| McKee, SA | 1 |
| Parale, MP | 1 |
| Kulkarni, SK | 1 |
4 other studies available for guanfacine and Depression
| Article | Year |
|---|---|
Topiramate for Posttraumatic Symptoms in an Obese Adolescent Girl.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Anticonvulsants; Antipsychotic Agents; Depression; | 2021 |
Interaction between noradrenergic and cholinergic signaling in amygdala regulates anxiety- and depression-related behaviors in mice.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Alkaloids; Amygdala; Animals; Anxiety; Azocines; Cholinest | 2018 |
Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice.
Topics: Animals; Antidepressive Agents; Brain; Depression; Female; Guanfacine; Heart Rate; Hindlimb Suspensi | 2015 |
Clonidine--induced behavioural despair in mice: reversal by antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Azepines; Clonidine; Depression; D | 1986 |