temozolomide has been researched along with Depression in 5 studies
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this sense, temozolomide, an alkylating/anti-proliferating agent used in treating brain cancer, is associated with decreased cognitive functions and depression." | 8.31 | Melatonin Prevents Depression but Not Anxiety-like Behavior Produced by the Chemotherapeutic Agent Temozolomide: Implication of Doublecortin Cells and Hilar Oligodendrocytes. ( Cabrera-Muñoz, EA; Díaz-Yañez, L; Meneses-San Juan, D; Ramírez-Rodríguez, GB; Reyes-Galindo, V; Vega-Rivera, NM, 2023) |
| "Radiotherapy, surgery and the chemotherapeutic agent temozolomide (TMZ) are frontline treatments for glioblastoma multiforme (GBM)." | 3.96 | Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy. ( Ahmed, F; Angulo, MC; Baulch, JE; Dey, D; Goldman, J; Klein, PM; Limoli, CL; Merriott, D; Moayyad, J; Murry, A; Nguyen, B; Nguyen, QA; Parihar, VK; Piomelli, D; Soltesz, I; Szabo, GG; Tran, J, 2020) |
| "The survival rate in high-grade glioma (HGG) patients receiving a combined regimen of radiotherapy (RT) and temozolomide after tumor resection was increased." | 3.88 | A prospective longitudinal evaluation of cognition and depression in postoperative patients with high-grade glioma following radiotherapy and chemotherapy. ( Chang, J; Di, J; Lu, X; Qi, F; Song, X; Wang, Q; Yu, Y; Zhang, L; Zhou, Y, 2018) |
| " However, vital safety and efficacy issues related to combined therapy with temozolomide, the first-line cytostatic in patients diagnosed with glioblastoma multiforme, and antidepressant drugs have yet to be addressed." | 3.85 | Antidepressant drugs can modify cytotoxic action of temozolomide. ( Bielecka, AM; Obuchowicz, E, 2017) |
| "Patients suffering from neuropathic pain have a higher incidence of depression and cognitive decline." | 1.51 | Environmental enrichment improves pain sensitivity, depression-like phenotype, and memory deficit in mice with neuropathic pain: role of NPAS4. ( Jia, M; Shen, JC; Wang, XM; Xie, ZM; Yang, JJ; Zhang, GF; Zhou, ZQ, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cabrera-Muñoz, EA | 1 |
| Ramírez-Rodríguez, GB | 1 |
| Díaz-Yañez, L | 1 |
| Reyes-Galindo, V | 1 |
| Meneses-San Juan, D | 1 |
| Vega-Rivera, NM | 1 |
| Dey, D | 1 |
| Parihar, VK | 1 |
| Szabo, GG | 1 |
| Klein, PM | 1 |
| Tran, J | 1 |
| Moayyad, J | 1 |
| Ahmed, F | 1 |
| Nguyen, QA | 1 |
| Murry, A | 1 |
| Merriott, D | 1 |
| Nguyen, B | 1 |
| Goldman, J | 1 |
| Angulo, MC | 1 |
| Piomelli, D | 1 |
| Soltesz, I | 1 |
| Baulch, JE | 1 |
| Limoli, CL | 1 |
| Wang, Q | 1 |
| Qi, F | 1 |
| Song, X | 1 |
| Di, J | 1 |
| Zhang, L | 1 |
| Zhou, Y | 1 |
| Lu, X | 1 |
| Chang, J | 1 |
| Yu, Y | 1 |
| Wang, XM | 1 |
| Zhang, GF | 1 |
| Jia, M | 1 |
| Xie, ZM | 1 |
| Yang, JJ | 1 |
| Shen, JC | 1 |
| Zhou, ZQ | 1 |
| Bielecka, AM | 1 |
| Obuchowicz, E | 1 |
5 other studies available for temozolomide and Depression
| Article | Year |
|---|---|
Melatonin Prevents Depression but Not Anxiety-like Behavior Produced by the Chemotherapeutic Agent Temozolomide: Implication of Doublecortin Cells and Hilar Oligodendrocytes.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Depression; Doublecortin Domain Proteins; Mel | 2023 |
Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy.
Topics: Animals; Anxiety; Behavior, Animal; Brain Neoplasms; CA1 Region, Hippocampal; Combined Modality Ther | 2020 |
A prospective longitudinal evaluation of cognition and depression in postoperative patients with high-grade glioma following radiotherapy and chemotherapy.
Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cogni | 2018 |
Environmental enrichment improves pain sensitivity, depression-like phenotype, and memory deficit in mice with neuropathic pain: role of NPAS4.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Depression; Environment; Hippocampus; Male; M | 2019 |
Antidepressant drugs can modify cytotoxic action of temozolomide.
Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; | 2017 |