Page last updated: 2024-11-05

zonisamide and Depression

zonisamide has been researched along with Depression in 4 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"We aimed to evaluate the effect of zonisamide (ZNS) on motor symptoms and nonmotor symptoms such as depressive symptoms and sleep problems in Parkinson's disease (PD) patients with or without tremor."5.41Zonisamide effects on sleep problems and depressive symptoms in Parkinson's disease. ( Fujita, H; Funakoshi, K; Haruyama, Y; Hirata, K; Kadowaki, T; Matsubara, T; Suzuki, K; Watanabe, Y, 2021)
" However, zonisamide- and carbamazepine-treated animals had IT values similar to those of controls, but only zonisamide significantly decreased absence seizure development."3.77Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model. ( Citraro, R; Constanti, A; De Fazio, S; De Sarro, G; Di Paola, ED; Perrota, I; Perrotta, I; Russo, E; Scicchitano, F, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Suzuki, K1
Fujita, H1
Matsubara, T1
Haruyama, Y1
Kadowaki, T1
Funakoshi, K1
Watanabe, Y1
Hirata, K1
Russo, E1
Citraro, R1
Scicchitano, F1
De Fazio, S1
Perrotta, I1
Perrota, I1
Di Paola, ED1
Constanti, A1
De Sarro, G1
Ozawa, K1
Kobayashi, K1
Noda, S1
Iyo, M1
Aylwin, S1
Al-Zaman, Y1

Reviews

1 review available for zonisamide and Depression

ArticleYear
Emerging concepts in the medical and surgical treatment of obesity.
    Frontiers of hormone research, 2008, Volume: 36

    Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Baria

2008

Trials

1 trial available for zonisamide and Depression

ArticleYear
Zonisamide effects on sleep problems and depressive symptoms in Parkinson's disease.
    Brain and behavior, 2021, Volume: 11, Issue:3

    Topics: Depression; Humans; Parkinson Disease; Sleep Wake Disorders; Tremor; Zonisamide

2021

Other Studies

2 other studies available for zonisamide and Depression

ArticleYear
Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model.
    Epilepsia, 2011, Volume: 52, Issue:7

    Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Depression; Dose-Response Relationship, Drug; Electr

2011
Zonisamide-induced depression and mania in patients with epilepsy.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1

    Topics: Adult; Bipolar Disorder; Depression; Epilepsy; Humans; Isoxazoles; Male; Polypharmacy; Treatment Out

2004