phenylalanine and Depression

phenylalanine has been researched along with Depression in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (40.54)	18.7374
1990's	1 (2.70)	18.2507
2000's	7 (18.92)	29.6817
2010's	8 (21.62)	24.3611
2020's	6 (16.22)	2.80

Authors

Authors	Studies
Chi, A; Khoo, S; Ng, SC; Zhao, S	1
Bai, D; Liu, H; Pu, J; Yang, L; Zhou, Q	1
Babson, K; Benca, RM; Bujanover, S; Krystal, AD; Lee, L; Malhotra, A; Rosenberg, R; Schweitzer, PK; Strohl, KP	1
Ching, J; Ho, CSH; Tay, GWN; Wee, HN	1
Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA	1
Baerwald, C; Heddrich-Ellerbrok, M; Hennermann, JB; Klimek, A; Lang, F; Ott, M; Parhofer, KG; Plöckinger, U; Rutsch, F; Schöne, K; Schwarz, M; Vom Dahl, S	1
Bosch, AM; Brouwers, MCGJ; de Sonneville, LMJ; de Vries, MC; Hofstede, FC; Hollak, CEM; Huijbregts, SCJ; Jahja, R; Janssen, MCH; Langendonk, JG; Legemaat, AM; Rubio-Gozalbo, ME; van der Meere, JJ; van der Ploeg, AT; van Spronsen, FJ	1
Beer, R; Ferger, B; Fuchs, D; Gaasch, M; Hackl, W; Helbok, R; Kofler, M; Pfausler, B; Rass, V; Rhomberg, P; Schiefecker, AJ; Schmutzhard, E; Sperner-Unterweger, B; Thomé, C	1
Blauth, M; Fuchs, D; Hüfner, K; Sperner-Unterweger, B	1
Han, XM; Lu, YN; Qin, YJ; Rang, Y; Wang, NX; Zhai, XJ; Zhang, XL; Zhu, Y	1
Denbow, DM; Funatsu, S; Furuse, M; Ikeda, H; Kawase, T; Kondoh, T; Nagasawa, M	1
Andersen, J; Bang-Andersen, B; Huber, T; Park, M; Rannversson, H; Sakmar, TP; Strømgaard, K; Sørensen, L	1
Zhang, W; Zhang, XA	1
Hashimoto, K; Inoue, T; Iwakura, Y; Izumi-Nakaseko, H; Kakuta, S; Kano, M; Katayama, N; Kiyama, Y; Manabe, T; Murphy, NP; Nakazawa, T; Sudo, K; Taniguchi, S; Tanimura, A; Tezuka, T; Umemori, H; Watabe, AM; Yamamoto, T; Yokoyama, K	1
McGill, J; Sharman, R; Sullivan, K; Young, RM	1
Guttler, F; Koch, R; Matalon, R; Moats, R; Moseley, KD; Yano, S	1
CUMINGS, JN; CURZON, G; GARDINER, D; PIERCY, MF; PRATT, RT	1
Ihle, D; Maes, M; Pilger, F; Rief, W; Scharpe, S; Verkerk, R	1
Antshel, KM; Gurian, EA; Waisbren, SE	1
Bilkei-Gorzo, A; Michel, K; Noble, F; Roques, BP; Zimmer, A	1
Coppen, A; Goodwin, BL; Rao, VA; Reynolds, GP; Ruthven, CR; Sandler, M	1
Gibert-Rahola, J; Maldonado, R; Mico, JA; Roques, BP; Tejedor-Real, P	1
Meyers, S	1
Campbell, IT; Harvie, MN; Howell, A; Thatcher, N	1
Wirz-Justice, A	1
Beckmann, H; Ludolph, E; Strauss, MA	1
Beckmann, H; Ludolph, E	1
Athen, D; Beckmann, H; Olteanu, M; Zimmer, R	1
Fischer, E; Heller, B; Martin, R	1
Frazer, A; Mendels, J	1
Fischer, E; Heller, B; Nachon, M; Spatz, H	1
Fischer, E	1
Chang, PN; Fisch, RO; Garfinkel, BD; Realmuto, GM; Shapiro, S; Tsai, MY; Tuchman, M	1
Aceto, MD; Brown, TG; Harris, LS; Lesher, GY; Pearl, J	1
Gilmour, DG; Manowitz, P; Racevskis, J	1
Birkmayer, W; Neumayer, E; Stöckl, W; Weiler, G	1

Reviews

2 review(s) available for phenylalanine and Depression

Article	Year
Trace amine deficit in depressive illness: the phenylalanine connexion. Acta psychiatrica Scandinavica. Supplementum, 1980, Volume: 280 Topics: Adult; Biogenic Amines; Depression; Female; Humans; Male; Middle Aged; Octopamine; Phenethylamines; Phenylalanine; Tyramine	1980
Use of neurotransmitter precursors for treatment of depression. Alternative medicine review : a journal of clinical therapeutic, 2000, Volume: 5, Issue:1 Topics: 5-Hydroxytryptophan; Depression; Humans; Phenylalanine; Tryptophan; Tyrosine	2000

Trials

5 trial(s) available for phenylalanine and Depression

Article	Year
Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression. Journal of psychiatric research, 2022, Volume: 155 Topics: Carbamates; Depression; Disorders of Excessive Somnolence; Double-Blind Method; Humans; Narcolepsy; Phenylalanine; Sleep Apnea, Obstructive; Treatment Outcome	2022
Dl-phenylalanine in depressed patients: an open study. Journal of neural transmission, 1977, Volume: 41, Issue:2-3 Topics: Adjustment Disorders; Adult; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Compulsive Behavior; Depression; Drug Evaluation; Emotions; Female; Humans; Hypochondriasis; Male; Middle Aged; Phenylalanine; Psychological Tests; Psychomotor Disorders; Sleep Wake Disorders	1977
[DL-phenylalanine as an antidepressant. Open study (author's transl)]. Arzneimittel-Forschung, 1978, Volume: 28, Issue:8 Topics: Adult; Aged; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Phenylalanine; Placebos; Time Factors	1978
DL-phenylalanine versus imipramine: a double-blind controlled study. Archiv fur Psychiatrie und Nervenkrankheiten, 1979, Jul-04, Volume: 227, Issue:1 Topics: Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Female; Humans; Imipramine; Male; Middle Aged; Phenylalanine	1979
Psychiatric diagnosis and behavioral characteristics of phenylketonuric children. The Journal of nervous and mental disease, 1986, Volume: 174, Issue:9 Topics: Adjustment Disorders; Adolescent; Adult; Attention; Attention Deficit Disorder with Hyperactivity; Child; Depression; Double-Blind Method; Female; Humans; Male; Phenylalanine; Phenylketonurias; Placebos; Psychiatric Status Rating Scales; Psychological Tests	1986

Other Studies

30 other study(ies) available for phenylalanine and Depression

Article	Year
Brain Functional Network and Amino Acid Metabolism Association in Females with Subclinical Depression. International journal of environmental research and public health, 2022, 03-11, Volume: 19, Issue:6 Topics: Brain; Depression; Electroencephalography; Female; Humans; Phenylalanine; Tryptophan; Tyrosine	2022
Peripheral blood and urine metabolites and biological functions in post-stroke depression. Metabolic brain disease, 2022, Volume: 37, Issue:5 Topics: Depression; Humans; Metabolomics; Phenylalanine; RNA, Transfer; Stroke	2022
The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity. International journal of molecular sciences, 2023, Jan-23, Volume: 24, Issue:3 Topics: Amino Acids; Aspartic Acid; Biomarkers; Depression; Depressive Disorder, Major; Glutamic Acid; Glycine; Humans; Phenylalanine	2023
Metabolomic markers of antepartum depression and suicidal ideation. Journal of affective disorders, 2020, 02-01, Volume: 262 Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Depression; Female; Humans; Logistic Models; Metabolomics; Odds Ratio; Patient Health Questionnaire; Peru; Phenylalanine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnant Women; Prospective Studies; Risk Factors; Suicidal Ideation; Triglycerides; Young Adult	2020
Everyday Life, Dietary Practices, and Health Conditions of Adult PKU Patients: A Multicenter, Cross-Sectional Study. Annals of nutrition & metabolism, 2020, Volume: 76, Issue:4 Topics: Activities of Daily Living; Adolescent; Adult; Amino Acids; Cross-Sectional Studies; Depression; Diet, Protein-Restricted; Dietary Supplements; Feeding Behavior; Female; Health Status; Humans; Male; Middle Aged; Patient Compliance; Phenylalanine; Phenylketonurias; Prevalence; Quality of Life; Surveys and Questionnaires; Young Adult	2020
Cognitive profile and mental health in adult phenylketonuria: A PKU-COBESO study. Neuropsychology, 2017, Volume: 31, Issue:4 Topics: Adolescent; Adult; Attention; Biopterins; Cognition; Depression; Executive Function; Female; Health Status; Humans; Inhibition, Psychological; Intelligence Tests; Male; Memory, Short-Term; Mental Health; Personality Disorders; Phenylalanine; Phenylketonurias; Self Report; Young Adult	2017
A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients. Scientific reports, 2019, 02-26, Volume: 9, Issue:1 Topics: Aged; Amino Acids; Brain; Depression; Female; Humans; Male; Microdialysis; Middle Aged; Phenylalanine; Subarachnoid Hemorrhage; Tryptophan; Tyrosine	2019
How acute and chronic physical disease may influence mental health - An Analysis of neurotransmitter precursor amino acid levels. Psychoneuroendocrinology, 2019, Volume: 106 Topics: Acute Disease; Adult; Aged; Amino Acids; Anxiety Disorders; C-Reactive Protein; Chronic Disease; Depression; Depressive Disorder; Female; Humans; Inflammation; Kynurenine; Male; Mental Disorders; Mental Health; Middle Aged; Neurotransmitter Agents; Phenylalanine; Prospective Studies; Tryptophan; Tyrosine	2019
Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats. Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174 Topics: Animals; Blood Chemical Analysis; Chromatography, Liquid; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Kynurenic Acid; Kynurenine; Limit of Detection; Linear Models; Male; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Tryptophan; Urinalysis	2019
Long-term consumption of dried bonito dashi (a traditional Japanese fish stock) reduces anxiety and modifies central amino acid levels in rats. Nutritional neuroscience, 2015, Volume: 18, Issue:6 Topics: 2-Aminoadipic Acid; Amino Acids; Animals; Anserine; Anxiety; Asparagine; Behavior, Animal; Cerebellum; Cystathionine; Depression; Diet; Fishes; Hippocampus; Hydroxyproline; Male; Methionine; Ornithine; Phenylalanine; Rats; Rats, Wistar; Seafood; Valine	2015
Genetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter. Nature communications, 2016, Apr-19, Volume: 7 Topics: Amino Acids; Antidepressive Agents; Binding Sites; Binding, Competitive; Depression; Humans; Models, Molecular; Molecular Structure; Mutation; Phenylalanine; Photochemical Processes; Protein Binding; Protein Structure, Tertiary; Serotonin Plasma Membrane Transport Proteins; Ultraviolet Rays	2016
A Novel Urinary Metabolite Signature for Non-invasive Post-stroke Depression Diagnosis. Cell biochemistry and biophysics, 2015, Volume: 72, Issue:3 Topics: Aged; Biomarkers; Caproates; Case-Control Studies; Depression; Dicarboxylic Acids; Female; Glyceric Acids; Humans; Hydroxy Acids; Male; Metabolome; Middle Aged; Phenylalanine; Pseudouridine; Stroke; Tyrosine	2015
Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. The EMBO journal, 2009, Dec-02, Volume: 28, Issue:23 Topics: Animals; Cell Line; Depression; Disease Models, Animal; Down-Regulation; Gene Knock-In Techniques; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylalanine; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tyrosine	2009
Depressive symptoms in adolescents with early and continuously treated phenylketonuria: associations with phenylalanine and tyrosine levels. Gene, 2012, Aug-10, Volume: 504, Issue:2 Topics: Adolescent; Depression; Humans; Phenylalanine; Phenylketonurias; Tyrosine	2012
Danger of high-protein dietary supplements to persons with hyperphenylalaninaemia. Journal of inherited metabolic disease, 2003, Volume: 26, Issue:4 Topics: Adolescent; Amino Acids; Biopterins; Depression; Dietary Supplements; Dose-Response Relationship, Drug; Headache; Humans; Male; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Somatotypes	2003
PHENYLALANINE TOLERANCE IN ENDOGENOUS DEPRESSION. The British journal of psychiatry : the journal of mental science, 1963, Volume: 109 Topics: Blood Chemical Analysis; Depression; Depressive Disorder; Humans; Phenylalanine; Urine	1963
Psychobiological aspects of somatoform disorders: contributions of monoaminergic transmitter systems. Neuropsychobiology, 2004, Volume: 49, Issue:1 Topics: Adult; Amino Acids, Branched-Chain; Analysis of Variance; Biogenic Monoamines; Case-Control Studies; Depression; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Interview, Psychological; Male; Middle Aged; Models, Biological; Phenylalanine; Somatoform Disorders; Tryptophan	2004
Maternal phenylketonuria: a case study suggesting the use of prenatal psychotherapy to help control phenylalanine levels. The American journal of orthopsychiatry, 2002, Volume: 72, Issue:4 Topics: Adult; Cognitive Behavioral Therapy; Depression; Female; Humans; Mothers; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Care; Surveys and Questionnaires	2002
Preproenkephalin knockout mice show no depression-related phenotype. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:11 Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Disulfides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Hindlimb Suspension; Immobility Response, Tonic; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Motor Activity; Nialamide; Phenotype; Phenylalanine; Protein Precursors; Swimming; Vocalization, Animal	2007
Implication of endogenous opioid system in the learned helplessness model of depression. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:1 Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Depression; Electroshock; Endorphins; Enkephalins; Helplessness, Learned; Hydroxamic Acids; Imipramine; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neprilysin; Phenylalanine; Protease Inhibitors; Rats; Rats, Wistar	1995
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2002, Volume: 15, Issue:3 Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine	2002
Theoretical and therapeutic potential of indolamine precursors in affective disorders. Neuropsychobiology, 1977, Volume: 3, Issue:4 Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine	1977
Therapeutic action of D-phenylalanine in Parkinson's disease. Arzneimittel-Forschung, 1976, Volume: 26, Issue:4 Topics: Depression; Humans; Parkinson Disease; Phenylalanine	1976
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania. The British journal of psychiatry : the journal of mental science, 1975, Volume: 126 Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Imipramine; Lithium; Methysergide; Monoamine Oxidase Inhibitors; Phenylalanine; Probenecid; Serotonin; Tryptophan	1975
Therapy of depression by phenylalanine. Preliminary note. Arzneimittel-Forschung, 1975, Volume: 25, Issue:1 Topics: Administration, Oral; Animals; Depression; Humans; Phenylalanine; Rats	1975
The phenethylamine hypothesis of thymic homeostasis. Biological psychiatry, 1975, Volume: 10, Issue:6 Topics: Antidepressive Agents; Brain; Depression; Homeostasis; Humans; Isomerism; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenethylamines; Phenylalanine; Thymus Gland	1975
Serotonin now: clinical implications of inhibiting its synthesis with para-chlorophenylalanine. Annals of internal medicine, 1970, Volume: 73, Issue:4 Topics: Adult; Aged; Animals; Behavior; Brain Chemistry; Catechols; Cattle; Depression; Diarrhea; Dogs; Enzyme Precursors; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Rabbits; Rats; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Sleep, REM; Testosterone; Tryptophan; Vasomotor System	1970
Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2 Topics: Amphetamine; Animals; Catecholamines; Chlorine; Depression; Drug Antagonism; Drug Synergism; Humans; Methyltyrosines; Mice; Motor Activity; Movement Disorders; Naphthyridines; Norepinephrine; Phenoxybenzamine; Phenylalanine; Piperidines; Reserpine; Stimulation, Chemical	1967
Low plasma tryptophan levels in recently hospitalized schizophrenics. Biological psychiatry, 1973, Volume: 6, Issue:2 Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Chronic Disease; Depression; Diet; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Schizophrenia; Sex Factors; Tryptophan; Tyrosine	1973
[Deficit of essential amino acids in endogenous depression]. Wiener klinische Wochenschrift, 1968, Nov-08, Volume: 80, Issue:45 Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Female; Humans; Injections, Intravenous; Male; Middle Aged; Phenylalanine; Tryptophan; Tyrosine	1968