anemoside A3: induces relaxation in rat renal arteries; from the root of Pulsatilla chinensis; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Pulsatilla | genus | A plant genus of the family RANUNCULACEAE. Members contain cernuosides and other oleanane and hederagenin saponins.[MeSH] | Ranunculaceae | The buttercup plant family of the order RANUNCULALES, class MAGNOLIOPSIDA. The leaves are usually alternate and stalkless. The flowers usually have two to five free sepals and may be radially symmetrical or irregular.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 11721847 |
| CHEMBL ID | 443387 |
| MeSH ID | M0449013 |
| Synonym |
|---|
| anemoside a3 |
| CHEMBL443387 |
| S9271 |
| 129724-84-1 |
| pulchinenoside a , |
| DTXSID60471131 |
| CS-5692 |
| HY-N0204 |
| AKOS030573551 |
| (1r,3as,5ar,5br,7ar,8r,9s,11ar,11br,13ar,13br)-9-(((2s,3r,4s,5s)-4,5-dihydroxy-3-(((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)tetrahydro-2h-pyran-2-yl)oxy)-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-(prop-1-en-2-yl)icosahydro- |
| ISNDTNDJSXYNKT-DVIRKNLQSA-N |
| CCG-270436 |
| MS-31319 |
| anemoside a3 pulchinenoside a3 |
| (3beta,4alpha)-3-[[2-o-(6-deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl]oxy]-23-hydroxylup-20(29)-en-28-oic acid |
| A888826 |
| pulchinenoside a3 |
| (1r,3as,5ar,5br,7ar,8r,9s,11ar,11br,13ar,13br)-9-[(2s,3r,4s,5s)-4,5-dihydroxy-3-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hex |
Anemoside A3 is a natural triterpenoid glycoside isolated from the root of Pulsatilla chinensis (Bunge) Regel.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Anemoside A3 (AA3) is a natural triterpenoid glycoside isolated from the root of Pulsatilla chinensis (Bunge) Regel. " | ( Anemoside A3 ameliorates experimental autoimmune encephalomyelitis by modulating T helper 17 cell response. Cheung, TH; Fu, G; Ip, FCF; Ip, NY; Li, JYH; Ng, YP; Or, TCT; Sun, P; Ye, WC, 2017) | 3.34 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID357922 | Cytotoxicity against human HL60 cells at 10 ug/mL by MTT assay | 2001 | Journal of natural products, Sep, Volume: 64, Issue:9 | New bisdesmosidic triterpene saponins from the roots of Pulsatilla chinensis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.43) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||