Page last updated: 2024-08-21

hesperidin and Depression

hesperidin has been researched along with Depression in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (66.67)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Bernroider, M; Chen, L; Feng, GW; Genser, J; Hierlmeier, G; Hu, XX; Lan, YJ; Leitner, C; Li, H; Lin, DF; Lyu, KY; Meng, L; Neubauer, F; Qu, X; Shen, T; Sun, RC; Wang, C; Weng, SF; Wolf, R; Xu, QY; Yang, SX; Yao, ZM; Zhang, LZ; Zhang, M; Zhang, NX; Zhang, X; Zhu, DX; Zhu, JJ; Zhu, S1
Cao, H; Huang, W; Lin, R; Liu, L; Nie, K; Peng, L; Yang, D; Zeng, Y; Zhang, M; Zhou, X1
Feng, F; Zhang, Q1
Antunes, MS; Araújo, SM; Boeira, SP; Bortolotto, VC; Cattelan Souza, L; Ladd, AABL; Ladd, FVL; Moreira, AL; Nogueira, CW; Prigol, M; Silva, MRP1
Alizadeh Makvandi, A; Amiri Moghaddam, S; Khalili, M; Roghani, M1
Chen, YJ; Liu, YW; Zhang, MY; Zhang, YM; Zhu, X1
Abbasi, MM; Ghorbanihaghjo, A; Kosari-Nasab, M; Salari, AA; Shokouhi, G1
Fu, H; Gao, X; Li, Y; Liu, L; Tong, Y; Wang, H; Wen, K; Xiao, D; Yong, J; Zhang, X; Zhao, J1
Bai, Y; Dai, G; Jing, W; Ju, W; Song, L; Song, S; Sun, H; Xu, M; Zhang, W; Zhang, Y1
Cai, L; Li, R; Wu, QQ; Wu, TN1
Du, B; Leng, X; Liu, F; Ren, F; Tang, X; Zhang, C; Zhao, G1
Abdallah, HM; El-Khatib, AS; El-Marasy, SA; El-Shabrawy, OA; El-Shenawy, SM; Kenawy, SA1
Li, M; Qin, B; Shao, H; Zhang, X1
Altvater, EET; Antunes, MS; Boeira, SP; de Oliveira Espinosa, D; Donato, F; Giacomeli, R; Gomes, NS; Jesse, CR; Ruff, JR1
Boeira, SP; de Gomes, MG; Del Fabbro, L; Filho, CB; Goes, AT; Jesse, CR; Souza, LC1

Other Studies

15 other study(ies) available for hesperidin and Depression

ArticleYear
    European journal of inorganic chemistry, 2022, Apr-08, Volume: 2022, Issue:10

    Topics: Accidents, Occupational; Adult; Animals; Anxiety; beta Catenin; Chromatography, High Pressure Liquid; Chronic Disease; Cities; Depression; Drugs, Chinese Herbal; Flavonoids; Heat Stroke; Hesperidin; Humans; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-10; Interleukin-6; Kruppel-Like Factor 4; Macrophages, Alveolar; Medical Staff; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Occupational Health; Occupational Injuries; Occupational Stress; Occupations; PPAR gamma; Pulmonary Fibrosis; RNA, Messenger; Sanitation; Silicon Dioxide; Sinusitis; Stress, Psychological; Surveys and Questionnaires; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; X-Box Binding Protein 1; Young Adult

2022
Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model.
    European journal of pharmacology, 2023, Aug-05, Volume: 952

    Topics: Animals; Caspase 1; Depression; Depressive Disorder, Major; Hesperidin; Humans; Inflammasomes; Molecular Docking Simulation; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats

2023
The Effects of Different Varieties of
    Molecules (Basel, Switzerland), 2019, Nov-22, Volume: 24, Issue:23

    Topics: Animals; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Flavanones; Hesperidin; Intestinal Absorption; Iridoids; Male; Rats; Rats, Sprague-Dawley

2019
Hesperidin Ameliorates Anxiety-Depressive-Like Behavior in 6-OHDA Model of Parkinson's Disease by Regulating Striatal Cytokine and Neurotrophic Factors Levels and Dopaminergic Innervation Loss in the Striatum of Mice.
    Molecular neurobiology, 2020, Volume: 57, Issue:7

    Topics: Animals; Anxiety; Behavior, Animal; Corpus Striatum; Cytokines; Depression; Dopaminergic Neurons; Hesperidin; Male; Mice; Nerve Growth Factors; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary

2020
Hesperetin ameliorates electroconvulsive therapy-induced memory impairment through regulation of hippocampal BDNF and oxidative stress in a rat model of depression.
    Journal of chemical neuroanatomy, 2021, Volume: 117

    Topics: Adrenergic Uptake Inhibitors; Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Electroconvulsive Therapy; Hesperidin; Hippocampus; Male; Maze Learning; Memory Disorders; Oxidative Stress; Rats; Rats, Wistar; Reserpine

2021
Hesperetin ameliorates diabetes-associated anxiety and depression-like behaviors in rats via activating Nrf2/ARE pathway.
    Metabolic brain disease, 2021, Volume: 36, Issue:7

    Topics: Animals; Anxiety; Depression; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Hesperidin; NF-E2-Related Factor 2; Oxidative Stress; Rats

2021
Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury.
    Life sciences, 2018, Nov-15, Volume: 213

    Topics: Animals; Antidepressive Agents; Brain Concussion; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Flavonoids; Hesperidin; Hippocampus; Inflammation; Interleukin-1beta; Male; Malondialdehyde; Mice; Nerve Growth Factors; Neuroprotective Agents; Oxidative Stress; Tumor Necrosis Factor-alpha

2018
The antidepressant effects of hesperidin on chronic unpredictable mild stress-induced mice.
    European journal of pharmacology, 2019, Jun-15, Volume: 853

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Survival; Cytokines; Depression; Hesperidin; HMGB1 Protein; Male; Membrane Glycoproteins; Mice; NF-kappa B; PC12 Cells; Protein-Tyrosine Kinases; Rats; Receptor for Advanced Glycation End Products; Signal Transduction; Stress, Psychological

2019
Comparative pharmacokinetic study of four major bioactive components after oral administration of Zhi-Zi-Hou-Po decoction in normal and corticosterone-induced depressive rats.
    Biomedical chromatography : BMC, 2019, Volume: 33, Issue:9

    Topics: Administration, Oral; Animals; Biphenyl Compounds; Corticosterone; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hesperidin; Iridoids; Lignans; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2019
[Effect of hesperidin on behavior and HPA axis of rat model of chronic stress-induced depression].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:2

    Topics: Administration, Oral; Animals; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Depression; Fluoxetine; Gene Expression Regulation; Hesperidin; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Models, Animal; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Psychological; Sucrose; Swimming; Up-Regulation

2013
Antidepressant-like effects of the hydroalcoholic extracts of Hemerocallis citrina and its potential active components.
    BMC complementary and alternative medicine, 2014, Sep-01, Volume: 14

    Topics: Animals; Antidepressive Agents; Depression; Dopamine; Hemerocallis; Hesperidin; Hindlimb Suspension; Male; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Rutin; Serotonin

2014
Anti-depressant effect of hesperidin in diabetic rats.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:11

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Factor; Depression; Diabetes Mellitus, Experimental; Fluoxetine; Glutathione; Hesperidin; Hyperglycemia; Inflammation; Interleukin-6; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Streptozocin

2014
Hesperidin Alleviates Lipopolysaccharide-Induced Neuroinflammation in Mice by Promoting the miRNA-132 Pathway.
    Inflammation, 2016, Volume: 39, Issue:5

    Topics: Animals; Antidepressive Agents; Brain Chemistry; Cytokines; Depression; Dose-Response Relationship, Drug; Hesperidin; Inflammation; Lipopolysaccharides; Metabolic Networks and Pathways; Mice; MicroRNAs

2016
Hesperidin reverses cognitive and depressive disturbances induced by olfactory bulbectomy in mice by modulating hippocampal neurotrophins and cytokine levels and acetylcholinesterase activity.
    European journal of pharmacology, 2016, Oct-15, Volume: 789

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition; Cytokines; Depression; Hesperidin; Hippocampus; Male; Maze Learning; Mice; Olfactory Bulb

2016
Evidence for the involvement of the serotonergic 5-HT(1A) receptors in the antidepressant-like effect caused by hesperidin in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jan-10, Volume: 40

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Exploratory Behavior; Fluoxetine; Hesperidin; Hindlimb Suspension; Immobility Response, Tonic; Male; Mice; Motor Activity; Prazosin; Receptor, Serotonin, 5-HT1A

2013