Page last updated: 2024-08-21

oleanolic acid and Depression

oleanolic acid has been researched along with Depression in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (61.54)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Jeon, M; Jung, SY; Kang, WC; Kim, DY; Kim, JY; Kong, CH; Lee, WH; Min, JW; Park, K; Ryu, JH1
Chao, B; Huang, S; Pan, J; Wang, Y; Zhang, Y1
Huang, F; Li, XZ; Ma, SP; Pan, YW; Su, J; Wang, SQ1
Hu, MZ; Li, YB; Liu, B; Mi, LF; Wang, AR; Zhang, ZL; Zhao, ZY; Zheng, S1
Kim, J; Lee, H; Mikami, T; Park, J; Suidasari, S; Yaicharoen, P; Yamauchi, K; Yokozawa, M1
Fang, F; Li, HW; Li, HY; Li, M; Ma, SP; Qin, TT; Qu, R; Ye, LY; Zeng, MJ; Zhao, YH1
Chen, SJ; Chen, XQ; Dong, SQ; Li, CD; Li, CF; Liang, WN; Wang, M; Wang, SS; Yi, LT1
Li, X; Pan, R; Song, M; Sun, X; Wang, Q; Xu, Y1
Deng, X; Guo, L; Ma, S; Su, J; Wang, S; Xu, L1
Gao, X; Qiao, M; Sun, P; Wei, S; Xue, L; Zhang, H1
Cao, C; Ding, H; Liu, Y1
Cheng, YF; Guo, HB; Huang, F; Liang, BF; Wang, GH; Wang, HT; Xu, JP; Yuan, X; Zhang, MZ1
Deng, YT; Feng, B; Han, J; Li, S; Wang, DS; Wang, XS; Yang, Q; Zhao, MG1

Other Studies

13 other study(ies) available for oleanolic acid and Depression

ArticleYear
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice.
    European journal of pharmacology, 2023, Oct-05, Volume: 956

    Topics: Animals; Depression; Female; Hippocampus; Male; Maternal Deprivation; Mice; Neuroinflammatory Diseases; Oleanolic Acid; Synaptophysin; Ursolic Acid

2023
Saikosaponin d downregulates microRNA-155 and upregulates FGF2 to improve depression-like behaviors in rats induced by unpredictable chronic mild stress by negatively regulating NF-κB.
    Brain research bulletin, 2020, Volume: 157

    Topics: Animals; Behavior, Animal; Depression; Fibroblast Growth Factor 2; Hindlimb Suspension; Hippocampus; Male; MicroRNAs; Neurons; NF-kappa B; Oleanolic Acid; Rats, Sprague-Dawley; Saponins; Signal Transduction; Stress, Psychological

2020
Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation.
    International immunopharmacology, 2020, Volume: 80

    Topics: Animals; Antidepressive Agents; Cell Survival; Cells, Cultured; Depression; Encephalitis; HMGB1 Protein; Lipopolysaccharides; Male; Mice, Inbred ICR; Microglia; NF-kappa B; Oleanolic Acid; Saponins; Signal Transduction; Toll-Like Receptor 4

2020
Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway.
    Behavioural brain research, 2021, 04-09, Volume: 403

    Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Depression; Disease Models, Animal; Hippocampus; Ischemic Stroke; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Recovery of Function; Saponins

2021
Olive leaf extract prevents obesity, cognitive decline, and depression and improves exercise capacity in mice.
    Scientific reports, 2021, 06-14, Volume: 11, Issue:1

    Topics: Animals; Cognitive Dysfunction; Depression; Diet, High-Fat; Disease Models, Animal; Exercise Tolerance; Humans; Iridoid Glucosides; Male; Mice; Mitochondria; Obesity; Olea; Oleanolic Acid; Oxidative Stress; Physical Conditioning, Animal; Plant Extracts; Plant Leaves; Receptors, G-Protein-Coupled

2021
Saikosaponin D relieves unpredictable chronic mild stress induced depressive-like behavior in rats: involvement of HPA axis and hippocampal neurogenesis.
    Psychopharmacology, 2017, Volume: 234, Issue:22

    Topics: Animals; Antidepressive Agents; Arousal; Corticosterone; Depression; Doublecortin Protein; Hippocampus; Hypothalamo-Hypophyseal System; Male; Motivation; Neurogenesis; Oleanolic Acid; Phytotherapy; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Saponins; Stress, Psychological

2017
Saikosaponin A attenuates perimenopausal depression-like symptoms by chronic unpredictable mild stress.
    Neuroscience letters, 2018, Jan-01, Volume: 662

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Brain-Derived Neurotrophic Factor; Depression; Female; Oleanolic Acid; Perimenopause; Rats; Rats, Wistar; Saponins; Stress, Psychological

2018
Total Saikosaponins of Bupleurum yinchowense reduces depressive, anxiety-like behavior and increases synaptic proteins expression in chronic corticosterine-treated mice.
    BMC complementary and alternative medicine, 2018, Apr-02, Volume: 18, Issue:1

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Bupleurum; Corticosterone; Depression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Oleanolic Acid; Plant Extracts; Receptors, AMPA; Saponins; Signal Transduction

2018
Modulation of LPA1 receptor-mediated neuronal apoptosis by Saikosaponin-d: A target involved in depression.
    Neuropharmacology, 2019, 09-01, Volume: 155

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line, Tumor; Coculture Techniques; Depression; Dose-Response Relationship, Drug; Humans; Lysophospholipids; Mice; Mice, Inbred ICR; Neurons; Oleanolic Acid; Random Allocation; Receptors, Lysophosphatidic Acid; Saponins

2019
Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint.
    Molecular medicine reports, 2014, Volume: 10, Issue:6

    Topics: Animals; Body Mass Index; Depression; Drugs, Chinese Herbal; Female; Fluoxetine; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Medicine, Chinese Traditional; Oleanolic Acid; Premenstrual Syndrome; Rats; Rats, Wistar; Saponins

2014
Pharmacological experimental study of the anti-depressant effect of total saikosaponins.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2014, Volume: 11, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hindlimb Suspension; Humans; Male; Mice; Motor Activity; Oleanolic Acid; Saponins

2014
Involvement of norepinephrine and serotonin system in antidepressant-like effects of hederagenin in the rat model of unpredictable chronic mild stress-induced depression.
    Pharmaceutical biology, 2015, Volume: 53, Issue:3

    Topics: Animals; Antidepressive Agents; Chronic Disease; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Psychological; Treatment Outcome

2015
Echinocystic acid reduces reserpine-induced pain/depression dyad in mice.
    Metabolic brain disease, 2016, Volume: 31, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Male; Mice, Inbred C57BL; Oleanolic Acid; Pain; Pain Threshold; Receptors, N-Methyl-D-Aspartate; Reserpine; Serotonin

2016