acetylcysteine and Depression

acetylcysteine has been researched along with Depression in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.17)29.6817
2010's16 (66.67)24.3611
2020's7 (29.17)2.80

Authors

AuthorsStudies
Cheraghian, B; Hosseini, SA; Khalatbari Mohseni, G; Majdinasab, N1
Aslanlar, DA; Nurullahoglu Atalik, KE; Oz, M; Vişneci, EF1
Baker, NL; Gilmore, AK; Gray, KM; Hood, CO; McClure, EA; McRae-Clark, AL; Sonne, SC; Squeglia, LM; Tomko, RL1
Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Srikumar, BN; Tripathi, SJ1
Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Tripathi, SJ1
Adler, CM; Blom, TJ; Cecil, KM; DelBello, MP; Nery, FG; Patino, LR; Tallman, MJ1
Ashton, M; Berk, M; Bortolasci, CC; Dean, OM; Gray, L; Jacka, F; Kowalski, GM; Liu, ZS; Marx, W; Mohebbi, M; Turner, A; Walder, K; Walker, AJ1
Chou, CP; Gray, KM; Hser, YI; Huang, D; McClure, E; Mooney, LJ; Tomko, RL; Zhu, Y1
Carstedt, P; Cullen, KR; Eberly, LE; Gunlicks-Stoessel, M; Klimes-Dougan, B; Marka, N; Miller, MJ; Nelson, K; Reigstad, K; Westervelt, A; Westlund Schreiner, M1
Baracat, M; Barbosa, DS; Machado, RCBR; Nunes, SOV; Pescim, RR; Porcu, M; Urbano, MR; Vargas, HO; Verri, WA1
Changotra, H; Gupta, GL; Yawalkar, R1
Gilmore, AK; Gray, KM; Tomko, RL1
Fernandes, J; Gupta, GL1
Białko, M; Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E1
Benvenutti, R; Elisabetsky, E; Hidalgo, MP; Levandovski, R; Melo, G; Pilz, LK; Quiles, CL; Trojan, Y1
Bloch, MH; Jakubovski, E; Mulqueen, JM; Panza, KE; Schumer, MC1
Berk, M1
Al-Rasheed, NM; Al-Rejaie, S; Al-Samhari, MM; Dzimiri, N; Hasan, IH; Mahmoud, AM1
Alvarenga, PG; Bloch, MH; Jakubovski, E; Landeros-Weisenberger, A; Leckman, JF; Mulqueen, JM; Panza, KE; Yaffa, A1
Atlas, D; Filip, M; Frankowska, M; Jastrzębska, J1
Anderson-Hunt, M; Berk, M; Bush, AI; Copolov, DL; Dean, O; Jeavons, S; Lu, K; Schapkaitz, I1
Allwang, C; Berk, M; Bush, AI; Cobb, H; Cotton, SM; Dean, O; Dodd, S; Fernandes, BS; Gama, CS; Hewitt, K; Jeavons, S; Kapczinski, F; Kohlmann, K; Malhi, GS; Schapkaitz, I1
Filip, M; Krzyżanowska, W; Miszkiel, J; Niedzielska, E; Ogórka, A; Pomierny, B; Pomierny-Chamioło, L; Smaga, I1

Reviews

1 review(s) available for acetylcysteine and Depression

ArticleYear
Acute poisoning following ingestion of medicines: initial management. How to treat life-threatening complications and to evaluate the risk of delayed effects and psychological distress.
    Prescrire international, 2010, Volume: 19, Issue:111

    Topics: Acetaminophen; Acetylcysteine; Acute Disease; Charcoal; Depression; Gastric Lavage; Humans; Poisoning; Risk

2010

Trials

11 trial(s) available for acetylcysteine and Depression

ArticleYear
Effects of N-acetylcysteine on oxidative stress biomarkers, depression, and anxiety symptoms in patients with multiple sclerosis.
    Neuropsychopharmacology reports, 2023, Volume: 43, Issue:3

    Topics: Acetylcysteine; Anxiety; Biomarkers; Depression; Glutathione; Humans; Multiple Sclerosis; Oxidative Stress

2023
Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder.
    Psychopharmacology, 2020, Volume: 237, Issue:2

    Topics: Acetylcysteine; Adult; Cannabis; Comorbidity; Depression; Double-Blind Method; Dronabinol; Female; Free Radical Scavengers; Humans; Male; Marijuana Abuse; Motivation; Treatment Outcome; Young Adult

2020
N-acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study.
    Early intervention in psychiatry, 2022, Volume: 16, Issue:2

    Topics: Acetylcysteine; Adolescent; Bipolar Disorder; Depression; Glutamic Acid; Humans; Pilot Projects; Prefrontal Cortex; Young Adult

2022
Baseline serum amino acid levels predict treatment response to augmentation with N-acetylcysteine (NAC) in a bipolar disorder randomised trial.
    Journal of psychiatric research, 2021, Volume: 142

    Topics: Acetylcysteine; Bipolar Disorder; Depression; Double-Blind Method; Drug Therapy, Combination; Humans; Treatment Outcome

2021
Reductions in cannabis use are associated with improvements in anxiety, depression, and sleep quality, but not quality of life.
    Journal of substance abuse treatment, 2017, Volume: 81

    Topics: Acetylcysteine; Adolescent; Adult; Antioxidants; Anxiety; Behavior Therapy; Depression; Female; Humans; Longitudinal Studies; Male; Marijuana Abuse; Marijuana Use; Middle Aged; Outcome Assessment, Health Care; Quality of Life; Sleep; Young Adult

2017
N-Acetylcysteine for Nonsuicidal Self-Injurious Behavior in Adolescents: An Open-Label Pilot Study.
    Journal of child and adolescent psychopharmacology, 2018, Volume: 28, Issue:2

    Topics: Acetylcysteine; Administration, Oral; Adolescent; Depression; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Humans; Impulsive Behavior; Pilot Projects; Psychiatric Status Rating Scales; Self-Injurious Behavior; Treatment Outcome; Young Adult

2018
Effects of adjunctive N-acetylcysteine on depressive symptoms: Modulation by baseline high-sensitivity C-reactive protein.
    Psychiatry research, 2018, Volume: 263

    Topics: Acetylcysteine; Adult; Biomarkers; C-Reactive Protein; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quality of Life; Treatment Outcome

2018
LONG-TERM OUTCOME IN PEDIATRIC TRICHOTILLOMANIA.
    Depression and anxiety, 2015, Volume: 32, Issue:10

    Topics: Acetylcysteine; Adolescent; Anxiety; Behavior Therapy; Child; Comorbidity; Depression; Double-Blind Method; Female; Humans; Male; Severity of Illness Index; Treatment Outcome; Trichotillomania

2015
N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On Trial.
    Journal of child and adolescent psychopharmacology, 2016, Volume: 26, Issue:4

    Topics: Acetylcysteine; Adolescent; Anxiety; Attention Deficit Disorder with Hyperactivity; Child; Depression; Double-Blind Method; Female; Free Radical Scavengers; Humans; Linear Models; Male; Obsessive-Compulsive Disorder; Severity of Illness Index; Tics; Tourette Syndrome; Treatment Outcome

2016
N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial.
    Biological psychiatry, 2008, Sep-15, Volume: 64, Issue:6

    Topics: Acetylcysteine; Adult; Antidepressive Agents; Bipolar Disorder; Depression; Double-Blind Method; Female; Humans; Male; Middle Aged; Surveys and Questionnaires

2008
The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial.
    Journal of affective disorders, 2011, Volume: 135, Issue:1-3

    Topics: Acetylcysteine; Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depression; Depressive Disorder; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Mood Disorders; Quality of Life; Severity of Illness Index; Treatment Outcome

2011

Other Studies

12 other study(ies) available for acetylcysteine and Depression

ArticleYear
N-acetylcysteine ameliorates chemotherapy-induced impaired anxiety and depression-like behaviors by regulating inflammation, oxidative and cholinergic status, and BDNF release.
    Behavioural brain research, 2024, Feb-26, Volume: 458

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Anxiety; Brain-Derived Neurotrophic Factor; Cholinergic Agents; Depression; Humans; Inflammation; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar

2024
N-acetyl cysteine ameliorates depression-induced cognitive deficits by restoring the volumes of hippocampal subfields and associated neurochemical changes.
    Neurochemistry international, 2020, Volume: 132

    Topics: Acetylcysteine; Animals; Cognitive Dysfunction; Depression; Hippocampus; Male; Organ Size; Random Allocation; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors

2020
Mechanisms underlying remediation of depression-associated anxiety by chronic N-acetyl cysteine treatment.
    Psychopharmacology, 2020, Volume: 237, Issue:10

    Topics: Acetylcysteine; Amygdala; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Corticosterone; Depression; Drug Administration Schedule; Free Radical Scavengers; Hippocampus; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Wistar; Treatment Outcome

2020
Protective influences of N-acetylcysteine against alcohol abstinence-induced depression by regulating biochemical and GRIN2A, GRIN2B gene expression of NMDA receptor signaling pathway in rats.
    Neurochemistry international, 2018, Volume: 118

    Topics: Acetylcysteine; Alcohol Abstinence; Animals; Brain; Depression; Dose-Response Relationship, Drug; Gene Expression; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2018
The role of depressive symptoms in treatment of adolescent cannabis use disorder with N-Acetylcysteine.
    Addictive behaviors, 2018, Volume: 85

    Topics: Acetylcysteine; Adolescent; Depression; Female; Free Radical Scavengers; Humans; Male; Marijuana Abuse; Young Adult

2018
N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat.
    Behavioural brain research, 2019, 05-17, Volume: 364

    Topics: Acetylcysteine; Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Inflammation; Male; Neuroimmunomodulation; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Stress, Psychological

2019
The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression.
    Behavioural brain research, 2014, Jun-01, Volume: 266

    Topics: Acetylcysteine; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration

2014
Effects of N-acetylcysteine and imipramine in a model of acute rhythm disruption in BALB/c mice.
    Chronobiology international, 2015, Volume: 32, Issue:2

    Topics: Acetylcysteine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Circadian Rhythm; Corticosterone; Depression; Disease Models, Animal; Imipramine; Interleukin-6; Light; Male; Mice; Mice, Inbred BALB C; Motor Activity; Photoperiod; Rest; Social Behavior; Temperature; Time Factors

2015
N-Acetylcysteine for Huntington's?
    The Australian and New Zealand journal of psychiatry, 2015, Volume: 49, Issue:11

    Topics: Acetylcysteine; Affect; Depression; Female; Humans; Huntington Disease; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Treatment Outcome

2015
Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects.
    Experimental biology and medicine (Maywood, N.J.), 2016, Volume: 241, Issue:5

    Topics: Acetylcysteine; Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Depression; Disease Models, Animal; Fluoxetine; Janus Kinases; Male; Oxidative Stress; Rats, Wistar; Signal Transduction; STAT Transcription Factors; Swimming

2016
N-acetylcysteine amide (AD4) reduces cocaine-induced reinstatement.
    Psychopharmacology, 2016, Volume: 233, Issue:18

    Topics: Acetylcysteine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Depression; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration

2016
N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Dec-03, Volume: 39, Issue:2

    Topics: Acetylcysteine; Animals; Antidepressive Agents; Antioxidants; Brain; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Imipramine; Immobility Response, Tonic; Male; Motor Activity; Olfactory Bulb; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2012