Page last updated: 2024-11-07

aldosterone and Depression

aldosterone has been researched along with Depression in 23 studies

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Sub-chronic tryptophan depletion (SCTD) is proposed as an animal model for depression."7.78Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity. ( Bermudez, I; Franklin, M; Gaburro, S; Murck, H; Singewald, N, 2012)
"Aldosterone treatment induced an anhedonic state manifested by decreased sucrose preference."5.38Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorder. ( Babic, S; Flynn, ME; Hlavacova, N; Jezova, D; Murck, H; Ondrejcakova, M; Poundstone, PK; Wes, PD, 2012)
" We have made advantage of a model of depression based on tryptophan depletion in which we have previously demonstrated that the elevation of serum aldosterone precedes that of corticosterone."3.83Adipogenesis and aldosterone: a study in lean tryptophan-depleted rats. ( Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Pokusa, M; Zorad, S, 2016)
"Sub-chronic tryptophan depletion (SCTD) is proposed as an animal model for depression."3.78Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity. ( Bermudez, I; Franklin, M; Gaburro, S; Murck, H; Singewald, N, 2012)
"Valproic acid treatment marginally enhanced global DNA methylation in the frontal cortex."1.51Brain derived neurotrophic factor expression and DNA methylation in response to subchronic valproic acid and/or aldosterone treatment. ( Balagova, L; Buzgoova, K; Graban, J; Hlavacova, N; Jezova, D, 2019)
"Hypertension and depression are frequent comorbidities of diabetes."1.40Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy. ( Ahola, AJ; Forsblom, C; Groop, PH; Harjutsalo, V, 2014)
"Aldosterone treatment induced an anhedonic state manifested by decreased sucrose preference."1.38Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorder. ( Babic, S; Flynn, ME; Hlavacova, N; Jezova, D; Murck, H; Ondrejcakova, M; Poundstone, PK; Wes, PD, 2012)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19905 (21.74)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (56.52)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Murck, H5
Lehr, L1
Jezova, D6
Izakova, L1
Hlavacova, N4
Segeda, V1
Kapsdorfer, D1
Morovicsova, E1
Schlageter, L2
Schneider, A2
Adolf, C3
Heinrich, D2
Quinkler, M2
Beuschlein, F3
Reincke, M5
Künzel, H3
Sbolli, M1
O'Connor, CM1
Ritzel, K1
Sturm, L1
Bogi, E1
Belovicová, K1
Ujhazy, E1
Mach, M1
Koprdova, R1
Zilava, L1
Garafová, A1
Dubovicky, M1
De Vos, AC1
Malan, L1
Seedat, YK1
Cockeran, M1
Malan, NT1
Engler, L1
Heinrich, DA1
Riester, A1
Franke, A1
Pawlowski, M1
Steiger, A1
Buzgoova, K1
Graban, J1
Balagova, L1
Häfner, S2
Baumert, J2
Emeny, RT2
Lacruz, ME2
Bidlingmaier, M2
Ladwig, KH2
Ahola, AJ1
Harjutsalo, V1
Forsblom, C1
Groop, PH1
Pokusa, M1
Csanova, A1
Franklin, M2
Zorad, S1
Ahmed, AH1
Calvird, M1
Gordon, RD1
Taylor, PJ1
Ward, G1
Pimenta, E1
Young, R1
Stowasser, M1
Wes, PD1
Ondrejcakova, M1
Flynn, ME1
Poundstone, PK1
Babic, S1
Kuenzel, H1
Holle, R1
Rupprecht, R1
Bermudez, I1
Singewald, N1
Gaburro, S1
Künzel, HE1
Bay-Richter, C1
Hallberg, L1
Ventorp, F1
Janelidze, S1
Brundin, L1
PILIEGO, N1
ROSSINI, P1
DELZOTTI, G1
SCARDAPANE, R1
Holsboer, F2
Dörr, HG1
Sippell, WG1
Zweifler, AJ1
Esler, M1
von Bardeleben, U1
Murphy, DL1
Goodwin, FK1
Bunney, WE1

Reviews

3 reviews available for aldosterone and Depression

ArticleYear
A viewpoint on aldosterone and BMI related brain morphology in relation to treatment outcome in patients with major depression.
    Journal of neuroendocrinology, 2023, Volume: 35, Issue:2

    Topics: Aldosterone; Body Mass Index; Brain; Depression; Depressive Disorder, Major; Humans; Hydrocortisone;

2023
Psychopathological symptoms in patients with primary hyperaldosteronism--possible pathways.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:3

    Topics: Aldosterone; Animals; Anxiety; Depression; Humans; Hyperaldosteronism; Mental Disorders; Psychopatho

2012
Human corticotropin releasing hormone: clinical studies in patients with affective disorders, alcoholism, panic disorder and in normal controls.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12 Suppl

    Topics: Adrenocorticotropic Hormone; Alcoholism; Aldosterone; Corticotropin-Releasing Hormone; Depression; D

1988

Trials

2 trials available for aldosterone and Depression

ArticleYear
Effects of two selective serotonin reuptake inhibitor antidepressants, sertraline and escitalopram, on aldosterone/renin ratio in normotensive depressed male patients.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:4

    Topics: Adult; Aldosterone; Antidepressive Agents; Blood Pressure; Citalopram; Depression; Humans; Hydrocort

2011
Aldosterone and sodium response to lithium administration in man.
    Lancet (London, England), 1969, Aug-30, Volume: 2, Issue:7618

    Topics: Adult; Aldosterone; Bipolar Disorder; Body Weight; Carbonates; Clinical Trials as Topic; Depression;

1969

Other Studies

18 other studies available for aldosterone and Depression

ArticleYear
Salivary Aldosterone, Cortisol, and Their Morning to Evening Slopes in Patients with Depressive Disorder and Healthy Subjects: Acute Episode and Follow-Up 6 Months after Reaching Remission.
    Neuroendocrinology, 2020, Volume: 110, Issue:11-12

    Topics: Acute Disease; Adult; Aldosterone; Anxiety; Bipolar Disorder; Circadian Rhythm; Depression; Depressi

2020
The potential pathophysiological role of aldosterone and the mineralocorticoid receptor in anxiety and depression - Lessons from primary aldosteronism.
    Journal of psychiatric research, 2020, Volume: 130

    Topics: Aldosterone; Anxiety; Depression; Female; Humans; Hyperaldosteronism; Hypertension; Male; Receptors,

2020
Aldosterone: Behind the Scenes of Depression and Heart Failure?
    JACC. Heart failure, 2020, Volume: 8, Issue:12

    Topics: Aldosterone; Depression; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Spironolacto

2020
Differential effects of reduced mineralocorticoid receptor activation by unilateral adrenalectomy vs mineralocorticoid antagonist treatment in patients with primary aldosteronism - Implications for depression and anxiety.
    Journal of psychiatric research, 2021, Volume: 137

    Topics: Adrenalectomy; Aldosterone; Anxiety; Depression; Female; Humans; Hyperaldosteronism; Male; Mineraloc

2021
Perinatal exposure to venlafaxine leads to lower anxiety and depression-like behavior in the adult rat offspring.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Animals, Newborn; Anxiety; Anxiety Disorders; Behavio

2018
Chronic depression symptoms desensitize renin activity to protect against volume-loading hypertension in Blacks: The SABPA study.
    Physiology & behavior, 2018, 10-01, Volume: 194

    Topics: Adult; Aldosterone; Black People; Blood Pressure; Depression; Female; Glomerular Filtration Rate; Hu

2018
Sleep-EEG in patients with primary aldosteronism in comparison to healthy controls and patients with depression.
    Journal of psychiatric research, 2019, Volume: 112

    Topics: Adolescent; Adult; Aged; Aldosterone; Anxiety; Blood Pressure; Depression; Depressive Disorder; Elec

2019
Brain derived neurotrophic factor expression and DNA methylation in response to subchronic valproic acid and/or aldosterone treatment.
    Croatian medical journal, 2019, Apr-30, Volume: 60, Issue:2

    Topics: Aldosterone; Animals; Brain; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Depression; Disease

2019
Hypertension and depressed symptomatology: a cluster related to the activation of the renin-angiotensin-aldosterone system (RAAS). Findings from population based KORA F4 study.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Cross-Sectional Studies; Depression; Female; Germany; H

2013
Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy.
    Acta diabetologica, 2014, Volume: 51, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensins; Antidepressive Agents; Antihypertensive Agents; Cross-Sectio

2014
Adipogenesis and aldosterone: a study in lean tryptophan-depleted rats.
    General physiology and biophysics, 2016, Volume: 35, Issue:3

    Topics: Adipogenesis; Aldosterone; Animals; Corticosterone; Depression; Female; Rats; Rats, Sprague-Dawley;

2016
Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorder.
    The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:2

    Topics: Aldosterone; Animals; Depression; Depressive Disorder, Major; Gene Expression Regulation; Hyperaldos

2012
To live alone and to be depressed, an alarming combination for the renin-angiotensin-aldosterone-system (RAAS).
    Psychoneuroendocrinology, 2012, Volume: 37, Issue:2

    Topics: Aldosterone; Depression; Female; Humans; Male; Middle Aged; Renin; Renin-Angiotensin System; Social

2012
Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity.
    Journal of psychiatric research, 2012, Volume: 46, Issue:2

    Topics: Aldosterone; Analysis of Variance; Animals; Body Weight; Brain; Calcium-Binding Proteins; Catecholam

2012
Aldosterone synergizes with peripheral inflammation to induce brain IL-1β expression and depressive-like effects.
    Cytokine, 2012, Volume: 60, Issue:3

    Topics: Aldosterone; Animals; Behavior, Animal; Cytokines; Depression; Depressive Disorder; Inflammation; In

2012
[THE EFFECTS OF AN OVERLOAD OF FOLLICULIN ON ALDOSTERONURIA AND CATECHOLAMINURIA IN NORMAL WOMEN AND IN PREMENSTRUAL SYNDROMES. RESEARCH ON THE RELATIONS BETWEEN URINARY MONOAMINES AND THE PSYCHOAFFECTIVE DISORDERS IN PATIENTS WITH PREMENSTRUAL TENSION].
    Folia endocrinologica, 1964, Volume: 17

    Topics: Aggression; Aldosterone; Anxiety; Catecholamines; Depression; Depressive Disorder; Emotions; Estradi

1964
Blunted aldosterone response to dexamethasone in female patients with endogenous depression.
    Psychoneuroendocrinology, 1982, Volume: 7, Issue:2-3

    Topics: Adult; Aldosterone; Depression; Dexamethasone; Female; Humans; Hydrocortisone; Middle Aged

1982
Factors influencing the choice of antihypertensive agents.
    Postgraduate medicine, 1976, Volume: 60, Issue:7

    Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications;

1976