Page last updated: 2024-11-03

psilocin and Depression

psilocin has been researched along with Depression in 2 studies

psilocin: psilocybine minus the phosphate ester; RN given refers to parent cpd; structure
psilocin : A tryptamine alkaloid that is N,N-dimethyltryptamine carrying an additional hydroxy substituent at position 4. A hallucinogenic alkaloid isolated in trace amounts from Psilocybe mushrooms (also known as Teonanacatl or "magic mushrooms").

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Using the Flinders Sensitive Line (FSL) rat model of depression, we assessed the antidepressant-like effect of psilocin and psilocybin, measured as a reduction in immobility time in the forced swim test (FST)."3.91Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat. ( Christiansen, SL; Elfving, B; Højgaard, K; Jefsen, O; Müller, HK; Nutt, DJ; Wegener, G, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Hess, EM1
Gould, TD1
Jefsen, O1
Højgaard, K1
Christiansen, SL1
Elfving, B1
Nutt, DJ1
Wegener, G1
Müller, HK1

Other Studies

2 other studies available for psilocin and Depression

ArticleYear
Possible psychedelic therapeutic mechanism.
    Science (New York, N.Y.), 2023, 02-17, Volume: 379, Issue:6633

    Topics: Animals; Depression; Hallucinogens; Humans; N,N-Dimethyltryptamine; Receptor, Serotonin, 5-HT2A; Ser

2023
Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat.
    Acta neuropsychiatrica, 2019, Volume: 31, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Male; Motor Ac

2019