Page last updated: 2024-10-17

hydrogen sulfide and Depression

hydrogen sulfide has been researched along with Depression in 11 studies

Hydrogen Sulfide: A flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
hydrogen sulfide : A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen.
thiol : An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Increasing evidence confirms that sleep deprivation (SD), which induces hippocampal neuroinflammation, is a risk factor for depression."5.62Hydrogen sulfide antagonizes sleep deprivation-induced depression- and anxiety-like behaviors by inhibiting neuroinflammation in a hippocampal Sirt1-dependent manner. ( Chen, YJ; Jiang, L; Kang, X; Lan, F; Tang, XQ; Tang, YY; Zhang, P; Zou, W, 2021)
"Depression is a common and debilitating mental illness and is often comorbid with anxiety disorders."5.39Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in behavioral models of depression and anxiety. ( Chen, WL; Hu, B; Niu, YY; Tang, XQ; Tian, Y; Xie, B; Xu, KL; Zhang, C; Zhang, P; Zou, W, 2013)
"Corticosterone, one of the glucocorticoids, is toxic to neurons and plays an important role in depressive-like behavior and depression."3.81H2S protects PC12 cells against toxicity of corticosterone by modulation of BDNF-TrkB pathway. ( Gao, S; Gu, H; Li, W; Tang, X; Tian, Y; Xiao, F; Zhang, P; Zou, W, 2015)
"Depression and schizophrenia are 2 serious mental disorders."3.01Gas therapy strategies for depression and schizophrenia: A review. ( Chen, F; Li, C; Lian, B; Liu, Y; Sun, L; Tao, X; Wang, D; Wang, L; Wang, Y; Zhu, X, 2023)
"Increasing evidence confirms that sleep deprivation (SD), which induces hippocampal neuroinflammation, is a risk factor for depression."1.62Hydrogen sulfide antagonizes sleep deprivation-induced depression- and anxiety-like behaviors by inhibiting neuroinflammation in a hippocampal Sirt1-dependent manner. ( Chen, YJ; Jiang, L; Kang, X; Lan, F; Tang, XQ; Tang, YY; Zhang, P; Zou, W, 2021)
"Therapies to treat chronic neuropathic pain and its associated comorbidities are limited."1.56Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation. ( Batallé, G; Cabarga, L; Pol, O, 2020)
"Hydrogen sulfide (H2S) is a crucial signaling molecule with a wide range of physiological functions."1.46Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress. ( Gu, HF; Kan, LY; Li, D; Liu, SY; Tang, XQ; Zeng, HY; Zhang, P; Zou, W, 2017)
"Depression is a common and debilitating mental illness and is often comorbid with anxiety disorders."1.39Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in behavioral models of depression and anxiety. ( Chen, WL; Hu, B; Niu, YY; Tang, XQ; Tian, Y; Xie, B; Xu, KL; Zhang, C; Zhang, P; Zou, W, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's6 (54.55)2.80

Authors

AuthorsStudies
Kang, X1
Jiang, L1
Lan, F1
Tang, YY3
Zhang, P6
Zou, W6
Chen, YJ2
Tang, XQ4
Du, L1
Chen, L1
Luo, B1
Jiang, JM1
Tao, X1
Zhu, X1
Liu, Y2
Wang, L1
Wang, D1
Sun, L1
Li, C2
Lian, B1
Wang, Y2
Chen, F1
Liu, HY1
Wei, HJ1
Wu, L1
Liu, SM1
Wang, CY1
Cabarga, L1
Batallé, G1
Pol, O1
Wang, S2
Xin, Y1
Zhang, J1
Yang, Z1
Liu, C1
Liu, SY1
Li, D1
Zeng, HY1
Kan, LY1
Gu, HF1
Chen, WL1
Xie, B1
Zhang, C1
Xu, KL1
Niu, YY1
Hu, B1
Tian, Y2
Zhang, L1
Meng, WQ1
Lu, L1
Xue, YS1
Zou, F1
Zhao, J1
Gao, S1
Li, W1
Xiao, F1
Gu, H1
Tang, X1
Saadat, M1
Zendeh-Boodi, Z1
Goodarzi, MA1

Reviews

1 review available for hydrogen sulfide and Depression

ArticleYear
Gas therapy strategies for depression and schizophrenia: A review.
    Medicine, 2023, Nov-17, Volume: 102, Issue:46

    Topics: Animals; Depression; Humans; Hydrogen Sulfide; Nitric Oxide; Prodrugs; Psychotic Disorders; Schizoph

2023

Other Studies

10 other studies available for hydrogen sulfide and Depression

ArticleYear
Hydrogen sulfide antagonizes sleep deprivation-induced depression- and anxiety-like behaviors by inhibiting neuroinflammation in a hippocampal Sirt1-dependent manner.
    Brain research bulletin, 2021, Volume: 177

    Topics: Animals; Anxiety; Depression; Hippocampus; Hydrogen Sulfide; Neuroinflammatory Diseases; Rats; Sirtu

2021
Silent information regulator 1 mediates H 2 S-inhibited chronic restraint stress-induced depressive-like behaviors by regulating hippocampal autophagy.
    Neuroreport, 2023, 02-01, Volume: 34, Issue:3

    Topics: Animals; Autophagy; Behavior, Animal; Depression; Hippocampus; Hydrogen Sulfide; Male; Rats; Rats, S

2023
BDNF-TrkB pathway mediates antidepressant-like roles of H
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:2

    Topics: Animals; Antidepressive Agents; Autophagy; Brain-Derived Neurotrophic Factor; Depression; Diabetes M

2020
Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation.
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:7

    Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Chronic Pain; Depression; Disease Models, Animal;

2020
Hydrogen sulfide alleviates the anxiety-like and depressive-like behaviors of type 1 diabetic mice via inhibiting inflammation and ferroptosis.
    Life sciences, 2021, Aug-01, Volume: 278

    Topics: Animals; Anti-Inflammatory Agents; Anxiety; Depression; Diabetes Mellitus, Type 1; Ferroptosis; Gaso

2021
Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress.
    The international journal of neuropsychopharmacology, 2017, 11-01, Volume: 20, Issue:11

    Topics: Animals; Antidepressive Agents; Caspase 12; Depression; Disease Models, Animal; Dose-Response Relati

2017
Antidepressant-like and anxiolytic-like effects of hydrogen sulfide in behavioral models of depression and anxiety.
    Behavioural pharmacology, 2013, Volume: 24, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Disease

2013
Selective detection of endogenous H₂S in living cells and the mouse hippocampus using a ratiometric fluorescent probe.
    Scientific reports, 2014, Jul-29, Volume: 4

    Topics: Animals; Carbamates; Cattle; Cystathionine beta-Synthase; Depression; Disease Models, Animal; Down-R

2014
H2S protects PC12 cells against toxicity of corticosterone by modulation of BDNF-TrkB pathway.
    Acta biochimica et biophysica Sinica, 2015, Volume: 47, Issue:11

    Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Hydrogen Sulfide; Membrane G

2015
Environmental exposure to natural sour gas containing sulfur compounds results in elevated depression and hopelessness scores.
    Ecotoxicology and environmental safety, 2006, Volume: 65, Issue:2

    Topics: Adult; Air Pollutants; Depression; Environmental Exposure; Female; Humans; Hydrogen Sulfide; Iran; L

2006