Page last updated: 2024-08-23

idazoxan and Depression

idazoxan has been researched along with Depression in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (6.25)	18.7374
1990's	8 (50.00)	18.2507
2000's	2 (12.50)	29.6817
2010's	5 (31.25)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bernard, R; Bernstein, HG; Laube, G; Veh, RW; Weiss, T	1
Li, JX; Seaman, RW; Shang, L; Siemian, JN; Zhang, Y; Zhu, Q	1
Doudet, DJ; Fontain, J; Iversen, P; Landau, AM; Lillethorup, TP; Wegener, G	1
Doudet, DJ; Iversen, P; Landau, AM; Lillethorup, TP; Wegener, G	1
Harvey, BH; Sallinen, J; Shahid, M; Uys, MM	1
Chen, HX; Jiang, XZ; Li, J; Li, YF; Wang, NP; Zhang, YZ	1
Huang, Y; O'Donnell, JM; Whisler, LR; Xiang, Y; Zhang, HT	1
Escribá, PV; García-Sevilla, J; Meana, JJ; Miralles, A; Olmos, G; Sastre, M	1
Paré, WP; Tejani-Butt, SM; Yang, J	1
McNamara, M; Nowak, G; Paul, IA; Piletz, JE; Redmond, A; Zhu, H	1
Callado, LF; García-Sevilla, JA; Grijalba, B; Meana, JJ; Pazos, A; Sastre, M	1
Grottick, AJ; Herberg, LJ; Montgomery, AM	1
Ghika, J; Growdon, J; Hoffman, E; Schoenfeld, D; Tennis, M	1
Bourin, M; Bradwejn, J; Hascoët, M	1
Cervo, L; Grignaschi, G; Samanin, R	1
Simson, PE; Weiss, JM	1

Reviews

1 review(s) available for idazoxan and Depression

Article	Year
I2-imidazoline receptors in the healthy and pathologic human brain. Annals of the New York Academy of Sciences, 1995, Jul-12, Volume: 763 Topics: Adrenergic alpha-2 Receptor Antagonists; Aging; Alzheimer Disease; Brain; Depression; Dioxanes; Glial Fibrillary Acidic Protein; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Monoamine Oxidase; Receptors, Adrenergic, alpha-2; Receptors, Drug; Suicide	1995

Article

Year

I2-imidazoline receptors in the healthy and pathologic human brain.

Annals of the New York Academy of Sciences, 1995, Jul-12, Volume: 763

Topics: Adrenergic alpha-2 Receptor Antagonists; Aging; Alzheimer Disease; Brain; Depression; Dioxanes; Glial Fibrillary Acidic Protein; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Monoamine Oxidase; Receptors, Adrenergic, alpha-2; Receptors, Drug; Suicide

1995

Trials

1 trial(s) available for idazoxan and Depression

Article	Year
Idazoxan treatment in progressive supranuclear palsy. Neurology, 1991, Volume: 41, Issue:7 Topics: Adrenergic alpha-Antagonists; Aged; Dementia; Depression; Dioxanes; Female; Gait; Humans; Idazoxan; Male; Movement; Severity of Illness Index; Supranuclear Palsy, Progressive	1991

Other Studies

14 other study(ies) available for idazoxan and Depression

Article	Year
Agmatine modulates spontaneous activity in neurons of the rat medial habenular complex-a relevant mechanism in the pathophysiology and treatment of depression? Translational psychiatry, 2018, 09-24, Volume: 8, Issue:1 Topics: Action Potentials; Agmatine; Animals; Benzofurans; Depression; Female; Habenula; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Middle Aged; Neurons; Rats, Wistar; Ureohydrolases	2018
Effects of imidazoline I2 receptor agonists on reserpine-induced hyperalgesia and depressive-like behavior in rats. Behavioural pharmacology, 2019, Volume: 30, Issue:5 Topics: Analgesics; Animals; Benzofurans; Depression; Disease Models, Animal; Fibromyalgia; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Imidazolines; Male; Pain; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Reserpine	2019
Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:3 Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Autoradiography; Biophysics; Brain; Depression; Disease Models, Animal; Electroshock; Female; Idazoxan; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium	2015
α2-adrenoceptor binding in Flinders-sensitive line compared with Flinders-resistant line and Sprague-Dawley rats. Acta neuropsychiatrica, 2015, Volume: 27, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic Neurons; Animals; Autoradiography; Brain; Depression; Disease Models, Animal; Female; Idazoxan; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2	2015
The α2C-adrenoceptor antagonist, ORM-10921, exerts antidepressant-like effects in the Flinders Sensitive Line rat. Behavioural pharmacology, 2017, Volume: 28, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Benzofurans; Cognitive Dysfunction; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Idazoxan; Imipramine; Male; Motor Activity; Quinolizidines; Rats; Swimming	2017
[5-HT1A/1B receptors, alpha2-adrenoceptors and the post-receptor adenylate cyclase activation in the mice brain are involved in the antidepressant-like action of agmatine]. Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:5 Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Agmatine; Animals; Antidepressive Agents; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Fenclonine; Idazoxan; Male; Mice; Pindolol; Random Allocation; Rats; Rats, Wistar; Receptors, Biogenic Amine; Serotonin 5-HT1 Receptor Antagonists; Swimming; Synapses; Yohimbine	2008
Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:4 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Tricyclic; Depression; Desipramine; Idazoxan; Male; Mice; Mice, Knockout; Motor Activity; Prazosin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Synapses	2009
Effect of repeated novel stressors on depressive behavior and brain norepinephrine receptor system in Sprague-Dawley and Wistar Kyoto (WKY) rats. Brain research, 1994, Jun-27, Volume: 649, Issue:1-2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Body Weight; Brain; Carrier Proteins; Depression; Dioxanes; Fluoxetine; Idazoxan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Pindolol; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic; Species Specificity; Stress, Psychological; Swimming; Symporters	1994
Chronic imipramine treatment upregulates IR2-imidazoline receptive sites in rat brain. Neurochemistry international, 1997, Volume: 30, Issue:1 Topics: Animals; Antidepressive Agents; Brain; Cell Membrane; Depression; Idazoxan; Imidazoline Receptors; Imipramine; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, Drug; Tritium; Up-Regulation	1997
Selective increase of alpha2A-adrenoceptor agonist binding sites in brains of depressed suicide victims. Journal of neurochemistry, 1998, Volume: 70, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Autoradiography; Binding, Competitive; Brain Chemistry; Brimonidine Tartrate; Cell Membrane; Clonidine; Depression; Female; Frontal Lobe; Humans; Idazoxan; Male; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2; Suicide; Tritium	1998
Rapid recovery of self-stimulation responding from depression by clozapine is prevented by the alpha 2-adrenoceptor agonist, clonidine. Behavioural pharmacology, 1999, Volume: 10, Issue:5 Topics: Adrenergic alpha-Agonists; Animals; Antipsychotic Agents; Clonidine; Clozapine; Depression; Dose-Response Relationship, Drug; Electric Stimulation; Idazoxan; Male; Rats; Risperidone; Self Stimulation; Tegmentum Mesencephali	1999
Behavioral models in mice. Implication of the alpha noradrenergic system. Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Depression; Dioxanes; Hydroxamic Acids; Idazoxan; Male; Mice; Motor Activity; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Swimming	1991
Alpha 2-adrenoceptor blockade prevents the effect of desipramine in the forced swimming test. European journal of pharmacology, 1990, Jan-17, Volume: 175, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Buspirone; Depression; Desipramine; Dioxanes; Hydroxydopamines; Idazoxan; Locus Coeruleus; Male; Motor Activity; Oxidopamine; Rats; Swimming	1990
Altered activity of the locus coeruleus in an animal model of depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1988, Volume: 1, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Depression; Dioxanes; Disease Models, Animal; Electrophysiology; Electroshock; Idazoxan; Locus Coeruleus; Male; Motor Activity; Neurons; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Stress, Psychological	1988