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5-methoxypsoralen and Depression

5-methoxypsoralen has been researched along with Depression in 3 studies

5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Coumarins are a large family of compounds, of natural and synthetic origin, that exhibit a variety of pharmacological activities, including MAO inhibition."6.49A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease. ( Bari, SB; Deshmukh, PK; Donda, ST; Firke, SD; Patil, DA; Patil, PO, 2013)
"To investigate if the coumarins prolong the behavioral effects of nicotine, the forced swimming test (FST)-animal models of depression, and passive avoidance (PA) test-memory and learning paradigm were used."3.83In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone. ( Biala, G; Budzynska, B; Kruk-Slomka, M; Skalicka-Wozniak, K; Wydrzynska-Kuzma, M, 2016)
"Coumarins are a large family of compounds, of natural and synthetic origin, that exhibit a variety of pharmacological activities, including MAO inhibition."2.49A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease. ( Bari, SB; Deshmukh, PK; Donda, ST; Firke, SD; Patil, DA; Patil, PO, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Patil, PO1
Bari, SB1
Firke, SD1
Deshmukh, PK1
Donda, ST1
Patil, DA1
Yan, M1
Bo, X1
Zhang, J1
Liu, S1
Li, X1
Liao, Y1
Liu, Q1
Cheng, Y1
Cheng, J1
Budzynska, B1
Skalicka-Wozniak, K1
Kruk-Slomka, M1
Wydrzynska-Kuzma, M1
Biala, G1

Reviews

1 review available for 5-methoxypsoralen and Depression

ArticleYear
A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2013, May-01, Volume: 21, Issue:9

    Topics: Alzheimer Disease; Coumarins; Depression; Drug Design; Humans; Models, Molecular; Molecular Structur

2013

Other Studies

2 other studies available for 5-methoxypsoralen and Depression

ArticleYear
Bergapten alleviates depression-like behavior by inhibiting cyclooxygenase 2 activity and NF-κB/MAPK signaling pathway in microglia.
    Experimental neurology, 2023, Volume: 365

    Topics: 5-Methoxypsoralen; Animals; Cyclooxygenase 2; Depression; Depressive Disorder, Major; Humans; Lipopo

2023
In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone.
    Psychopharmacology, 2016, Volume: 233, Issue:12

    Topics: 5-Methoxypsoralen; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Coumarins;

2016