domperidone has been researched along with Depression in 5 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the therapeutic effect of Modified Banxia Houpo Decoction (MBHD) in treating patients with functional dyspepsia (FD) accompanied with psychological factors, and to compare it with Domperidone, Neurostan, and Domperidone + Neurostan." | 5.17 | [Randomized controlled trial of modified banxia houpo decoction in treating functional dyspepsia patients with psychological factors]. ( Li, Y; Xiao, L, 2013) |
| " Imipramine was administered for the next 5 weeks, and it reversed anhedonia in majority of animals (imipramine-reactive); however, in some animals, it did not (imipramine-non-reactive)." | 3.88 | Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat. ( Antkiewicz-Michaluk, L; Dziedzicka-Wasylewska, M; Faron-Górecka, A; Gruca, P; Kolasa, M; Kuśmider, M; Pabian, P; Papp, M; Romańska, I; Solich, J; Szlachta, M; Żurawek, D, 2018) |
| " The off-awake daily duration and the levodopa dosage were significantly reduced in the patients infused with apomorphine." | 2.71 | Continuous apomorphine infusion (CAI) and neuropsychiatric disorders in patients with advanced Parkinson's disease: a follow-up of two years. ( Antonini, A; Basile, G; Di Rosa, AE; Di Rosa, E; Epifanio, A; La Spina, P; Marconi, R; Martino, G; Morgante, L; Nicita-Mauro, V; Spina, E; Stocchi, F, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faron-Górecka, A | 2 |
| Kuśmider, M | 2 |
| Solich, J | 1 |
| Kolasa, M | 2 |
| Pabian, P | 1 |
| Gruca, P | 2 |
| Romańska, I | 1 |
| Żurawek, D | 2 |
| Szlachta, M | 1 |
| Papp, M | 2 |
| Antkiewicz-Michaluk, L | 1 |
| Dziedzicka-Wasylewska, M | 2 |
| Xiao, L | 1 |
| Li, Y | 1 |
| Morgante, L | 1 |
| Basile, G | 1 |
| Epifanio, A | 1 |
| Spina, E | 1 |
| Antonini, A | 1 |
| Stocchi, F | 1 |
| Di Rosa, E | 1 |
| Martino, G | 1 |
| Marconi, R | 1 |
| La Spina, P | 1 |
| Nicita-Mauro, V | 1 |
| Di Rosa, AE | 1 |
| Zhao, L | 1 |
| Gan, AP | 1 |
3 trials available for domperidone and Depression
| Article | Year |
|---|---|
[Randomized controlled trial of modified banxia houpo decoction in treating functional dyspepsia patients with psychological factors].
Topics: Adolescent; Adult; Anxiety Disorders; Depression; Domperidone; Drugs, Chinese Herbal; Dyspepsia; Fem | 2013 |
Continuous apomorphine infusion (CAI) and neuropsychiatric disorders in patients with advanced Parkinson's disease: a follow-up of two years.
Topics: Antiemetics; Apomorphine; Brain; Cognition Disorders; Depression; Domperidone; Dopamine Agonists; Dr | 2004 |
Clinical and psychological assessment on xinwei decoction for treating functional dyspepsia accompanied with depression and anxiety.
Topics: Adult; Anxiety Disorders; Depression; Domperidone; Dopamine Antagonists; Drugs, Chinese Herbal; Dysp | 2005 |
2 other studies available for domperidone and Depression
| Article | Year |
|---|---|
Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat.
Topics: Anhedonia; Animals; Antidepressive Agents; Autoradiography; Brain; Depression; Disease Models, Anima | 2018 |
Mesolimbic dopamine D₂ receptor plasticity contributes to stress resilience in rats subjected to chronic mild stress.
Topics: Animals; Brain; Depression; Disease Models, Animal; Domperidone; Gene Expression Regulation; Male; R | 2013 |