tryptophan has been researched along with Depression in 566 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 246 (43.46) | 18.7374 |
| 1990's | 33 (5.83) | 18.2507 |
| 2000's | 63 (11.13) | 29.6817 |
| 2010's | 144 (25.44) | 24.3611 |
| 2020's | 80 (14.13) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, YL; Gao, LN; Li, K; Li, KD; Liu, H; Wang, QS; Wang, X; Yan, K; Zhang, Z | 1 |
| Bian, Z; Chen, Y; Cheng, C; Deng, Y; Fang, X; Han, L; Huang, L; Huang, S; Huang, T; Li, S; Lin, C; Liu, Z; Lu, L; Luo, W; Mo, Z; Ning, Z; Qiu, Q; Shang, X; Xiong, T; Yang, C; Yang, W; Zhai, L; Zhao, L; Zhong, LLD; Zhou, Y | 1 |
| Ataei, S; Azcarate-Peril, A; Carroll, I; Fransson, E; Jin, W; Kimmel, M; Knickmeyer, R; Lun, K; Meltzer-Brody, S; Plantinga, A; Rackers, H; Wu, M; Xia, K | 1 |
| Kanova, M; Kohout, P | 1 |
| Ahmad, S; Alam, M; Azizuddin, -; Khaliq, S; Mustafa, S; Raza, U; Samad, N; Yasmin, F | 1 |
| Chen, W; Chen, Y; Qian, L; Qian, X; Tian, P; Wang, G; Wang, L; Wang, Q; Zhang, H; Zhao, J; Zhu, H; Zou, R | 1 |
| Bai, M; Chen, C; Chen, X; Chen, Z; Cheng, K; Fang, L; He, Y; Lan, T; Li, Y; Tian, Y; Wang, Y; Wu, Z; Xie, P; Xu, X; Yang, D; Yu, H; Zhao, L | 1 |
| Anesi, A; Aouizerate, B; Aubert, A; Beau, C; Capuron, L; Cussotto, S; Delgado, I; Dexpert, S; Forestier, D; Ledaguenel, P; Magne, E; Mattivi, F | 1 |
| Aranyi, CS; Bagdy, G; Baksa, D; Dobos, D; Emri, M; Galambos, A; Gecse, K; Juhasz, G; Kocsel, N; Kökönyei, G; Ludányi, K; Pap, D; Szabó, E; Virág, D | 1 |
| Achtyes, ED; Brundin, L; Escobar Galvis, ML; Fazleabas, AT; Keaton, S; Krzyzanowski, S; Leach, R; Madaj, Z; Postolache, TT; Sha, Q; Smart, L | 1 |
| Savitz, J | 1 |
| Chi, A; Khoo, S; Ng, SC; Zhao, S | 1 |
| Chen, W; Chen, X; Chen, Y; Gong, X; Gui, S; Li, W; Liu, L; Liu, Y; Pu, J; Tian, L; Wang, D; Wang, H; Xie, P; Yu, Y; Zhong, X | 1 |
| Śliwiński, T; Wigner, P | 1 |
| Bai, W; Liu, X; Lu, L; Pan, W; Shi, R; Wang, D; Wang, Y; Wu, J; Xia, B; Xie, H; Ye, J; Zhao, B; Zhao, Z; Zhu, P | 1 |
| Buyukkoruk, M; Candansayar, S; Deveci-Bulut, TS; Gulbahar, O; Kucukkarapinar, M; Senol, E; Yay-Pence, A; Yaz-Aydin, G; Yildiz, Y | 1 |
| Amendola, S; Cooper, RE; Hengartner, MP; Horowitz, MA; Moncrieff, J; Stockmann, T | 1 |
| Arakawa, M; Miyake, Y; Okubo, H; Sasaki, S; Tanaka, K | 1 |
| Correia, AS; Vale, N | 1 |
| Fan, B; Li, S; Liu, X; Lu, C; Tong, L; Wang, F; Wang, Y; Wei, Z | 1 |
| Kim, SY; Liaqat, H; Parveen, A | 1 |
| Khan, S; Khatri, DK; Rathour, D; Shah, S; Singh, PK; Singh, SB; Srivastava, S | 1 |
| Chang, R; Gong, X; Huang, Z; Tan, S; Zou, J | 1 |
| Ge, PY; Guo, R; Ni, SJ; Qi, YY; Qu, SY; Yang, NY; Yao, ZY; Zhang, QC; Zhao, X; Zhu, HX | 1 |
| Gao, X; Gao, Y; Gu, Y; Li, J; Ni, W; Su, J; Weng, R; Xiao, W; Yang, H | 1 |
| Cubała, WJ; Gruchała-Niedoszytko, M; Małgorzewicz, S; Mechlińska, A; Włodarczyk, A | 1 |
| Chen, S; Chen, Z; Li, Q; Lin, S; Tao, Y; Tong, Y; Wang, P; Wang, T; Xu, Z | 1 |
| Graor, HJ; Hajihassani, O; Hue, JJ; Ji, K; Katayama, ES; Loftus, AW; Vaziri-Gohar, A; Winter, JM; Zarei, M | 1 |
| Almulla, AF; Maes, M | 1 |
| Chen, B; Di, Z; Guo, Q; Hu, R; Jiang, S; Liu, J; Ma, R; Shi, M; Song, Z; Sun, S; Wu, X; Xu, H | 1 |
| Bao, Y; Huang, X; Jin, Y; Lin, F; Lu, L; Ma, Y; Ren, H; Tan, L; Wang, F; Wu, L; Xie, X; Zhang, Y | 1 |
| Chen, B; Chen, L; Chen, Y; Deng, Y; Feng, Y; Guan, H; Huang, A; Huang, P; Huang, X; Lei, S; Li, Z; Peng, W; Xie, D; Yan, L; Yu, L; Zeng, J; Zhao, S | 1 |
| Aydin, A; Mat, AF; Ozhan, Y; Sipahi, H | 1 |
| Xu, X; Yan, B; Zhu, K | 1 |
| Abuelezz, SA; Hendawy, N; Salaheldin, TH | 1 |
| Huang, Z; Lai, W; Li, S; Li, XG; Luo, D | 1 |
| Cheng, S; Ho, CSH; Ho, RCM; Jiang, Z; Li, H; Liu, D; Pan, F; Wang, W; Zhu, Z | 1 |
| Chen, JJ; Niu, L; Wang, S; Wang, Y; Wu, D; Wu, WT; Xie, J; Zeng, Y; Zhong, Q | 1 |
| Chen, H; He, X; Kan, Q; Li, Y; Liang, X; Liu, R; Luo, J; Shi, F; Song, X; Tang, H; Ye, G; Zhao, L; Zou, Y | 1 |
| Antal, P; Bagdy, G; Bolgar, B; Bruncsics, B; Burden, ST; Deakin, B; Eszlari, N; Gecse, K; Gonda, X; Hullam, G; Jones, DJ; Juhasz, G; Millinghoffer, A; Petschner, P | 1 |
| Chen, Y; Guo, M; He, J; Li, Z; Liu, Y; Maitiniyazi, G; Tao, W; Xia, S | 1 |
| Bobrovskaya, L; Herselman, MF; Lin, L; Luo, S; Yamanaka, A; Zhou, XF | 1 |
| Fan, Y; Gao, R; Liu, W; Wang, J; Wang, S; Wu, L; Xu, H; Xu, L; Yao, H; Yu, J; Yu, Z; Zhang, J; Zhang, L; Zhou, M | 1 |
| Badawy, AA; Bano, S; Hamid, SB; Sajid, F; Sharif, H | 1 |
| Bi, Y; Chen, Y; Ju, Y; Li, L; Liao, M; Liu, B; Liu, J; Ma, M; Ou, W; Qin, Y; Zhang, Y | 1 |
| Maeda, R; Mimura, M; Suematsu, M; Sugiura, Y; Sugiyama, E; Tanaka, KF; Uchida, H; Uchida, T | 1 |
| Diao, J; Li, L; Meng, Z; Sun, W; Tian, S; Yan, S; Zhou, Z; Zhu, W | 1 |
| Coppens, V; de Boer, P; Fransen, E; Lai, FY; Morrens, M; Sabbe, B; Schuermans, J; Timmers, M; van den Ameele, S; van Diermen, L; van Nuijs, AL; Verkerk, R | 1 |
| Chang, Q; Chen, SG; Feng, L; Liu, XM; Tao, X; Wang, LS; Wang, Z; Zhang, MD; Zhou, YF | 1 |
| Cui, C; Li, W; Liu, S; Sun-Waterhouse, D; Tao, Q; Zhu, X | 1 |
| Bouma, G; de Jong, WH; de Vries, EG; Kema, IP; Meijer, C; Oosting, SF; Peters, MA; Ruhé, HG; van Faassen, M; Walenkamp, AM | 1 |
| Akamatsu, Y; Hayashi, T; Moritani, T; Nishida, MM; Tsujita, N | 1 |
| Baer, W; Felger, JC; Goldsmith, DR; Haroon, E; Miller, AH; Patel, T; Welle, JR; Woolwine, BJ | 1 |
| Amini, M; Hosseinzadeh, M; Khosravi, M; Mansoori, A; Raisi, F; Sotoudeh, G | 1 |
| Egger, EM; Fuchs, D; Kink, P; Kurz, K; Lanser, L; Weiss, G; Willenbacher, W | 1 |
| Klimova, B; Novotny, M; Valis, M | 1 |
| Bigot, M; Chevalier, G; Eberl, G; Katsimpardi, L; Lledo, PM; Moigneu, C; Saha, S; Siopi, E | 1 |
| Ahmad, FJ; Akhtar, M; Alam, M; Imam, SS; Najmi, AK; Zameer, S | 1 |
| Araújo, G; Carabelli, B; de Souza, LER; Delattre, AM; Ferraz, AC; Machado, RB; Suchecki, D; Waltrick, APF; Zanata, SM; Zanoveli, JM | 1 |
| Abo, M; Hara, T; Hashimoto, K; Ishima, T; Niimi, M; Yamada, N | 1 |
| Chang, Q; Gan, L; Jiang, N; Li, CC; Liu, XM; Pan, RL; Zhao, MJ | 1 |
| Shader, RI | 1 |
| Barger, GR; John, F; Juhász, C; Michelhaugh, SK; Mittal, S | 1 |
| Candido, KD; Jovanovic, F; Knezevic, NN | 1 |
| Cuellar Leal, VA; Dantzer, R; de Dios, C; Hunt, C; Macedo E Cordeiro, T; Selvaraj, S; Soares, JC; Suchting, R; Teixeira, AL | 1 |
| Boeira, SP; Cattelan Souza, L; de Brito, MLO; de Gomes, MG; Fabbro, LD; Goes, ATR; Jesse, CR; Machado, FR; Nogueira, CW; Prigol, M | 1 |
| Anderson, G; Broch, L; Celius, EG; Maes, DM; Ormstad, H; Simonsen, CS | 1 |
| Blasiak, J; Chojnacki, C; Chojnacki, J; Fila, M; Konrad, P; Popławski, T | 1 |
| Aprano, S; Barrea, L; Castellucci, B; Colao, A; Laudisio, D; Muscogiuri, G; Pugliese, G; Savastano, S | 1 |
| Brown, J; Clarke, G; Collins, JM; Cryan, JF; Dinan, TG; Keane, JM; Kenny, LC; Khashan, AS; McCarthy, FP; O'Donovan, S; O'Mahony, SM | 1 |
| Białek, K; Bijak, M; Czarny, P; Gruca, P; Jóźwiak, P; Papp, M; Śliwiński, T; Synowiec, E; Szemraj, J; Wigner, P | 1 |
| Bravo, R; Kirsch, P; Plieger, T; Reuter, M; Rodriguez, AB; Ugartemendia, L; Zamoscik, V | 1 |
| Bugajska, J; Inglot, M; Janocha-Litwin, J; Malyszczak, K; Marciniak, D; Pawlak, D; Pawlowski, T; Zalewska, M | 1 |
| Chamli Hårsmar, S; Lindahl, J; Lindqvist, D; Söderberg, G; Suneson, K | 1 |
| Deng, G; Dong, Z; Gao, L; Gao, T; Huang, P; Li, Y; Lv, Z; Wong, NK; Wu, Z; Zeng, T | 1 |
| Drivsholm, N; Faurholt-Jepsen, M; Gelpi, M; Kirkegaard-Klitbo, DM; Knudsen, AD; Midttun, Ø; Nielsen, SD; Trøseid, M; Ueland, PM | 1 |
| Goel, RK; Singh, T | 1 |
| Bravo, R; Castaño, MY; Kirsch, P; Plieger, T; Reuter, M; Rodríguez, AB; Ugartemendia, L; Zamoscik, V | 1 |
| Grochans, E; Lubkowska, A; Panczyk, M; Schneider-Matyka, D; Szkup, M | 1 |
| Coppens, V; De Picker, L; Giltay, EJ; Hebbrecht, K; Morrens, M; Skorobogatov, K | 1 |
| Bao, CH; Chen, LM; Huang, Y; Liang, SH; Liu, HR; Wang, D; Wu, HG; Wu, LY; Wu, Y | 1 |
| Allers, KA; Beekman, ATF; Giltay, EJ; Keller, S; Milaneschi, Y; Niessen, HG; Penninx, BWJH; Schoevers, RA; Süssmuth, SD | 1 |
| Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A | 1 |
| Abautret-Daly, Á; Connor, TJ; de Francisco-García, R; Dempsey, E; Harkin, A; Medina, C; Parra-Blanco, A; Riestra, S; Rodrigo, L | 1 |
| Brown, J; Finkelstein, FO; Garimella, PS; Handelman, GJ; Ikizler, A; Ix, JH; Kooman, J; Kotanko, P; Levin, NW; Malhotra, R; Persic, V; Rosales, L; Tao, X; Thijssen, S; Unruh, ML; Zhang, W | 1 |
| Liu, QZ; Shang, J; Wang, H; Wang, LL; Zhou, J | 1 |
| Chaves Filho, AJM; de Lucena, DF; Lima, CNC; Macedo, D; Maes, M; Vasconcelos, SMM | 1 |
| de Jonge, P; Doornbos, B; Kema, IP; Penninx, BWJH; Sorgdrager, FJH | 1 |
| Ahmed, M; Azmat, A | 1 |
| Anderson, G; Carvalho, AF; Galecki, P; Kanchanatawan, B; Maes, M; Sirivichayakul, S | 1 |
| Agudelo, LZ; Cervenka, I; Ruas, JL | 1 |
| Can, A; Fuchs, D; Groer, M; Krishnamurthy, VB; Millett, CE; Mukherjee, D; Postolache, TT; Reider, A; Saunders, EFH | 1 |
| Khanam, R; Thomas, J; Vohora, D | 1 |
| Czarny, P; Galecki, P; Sliwinski, T; Su, KP; Wigner, P | 1 |
| Brandmayr, W; Enko, D; Halwachs-Baumann, G; Kriegshäuser, G; Mangge, H; Meinitzer, A; Schnedl, WJ; Wagner, H; Zelzer, S | 1 |
| Ding, L; Jiang, X; Jing, C; Liu, F; Pang, C; Yan, Q; Zhang, L | 1 |
| Jeon, SW; Kim, YK | 1 |
| Dong, X; Gong, H; Jiang, CL; Lian, YJ; Liu, LL; Peng, W; Su, WJ; Wang, B; Wang, YX; Zhang, T | 1 |
| Czarny, P; Galecki, P; Sliwinski, T; Wigner, P | 1 |
| Chen, B; Guo, J; He, S; Hu, J; Hu, L; Huang, X; Li, X; Qi, Y; Shang, D; Wang, J; Wen, Y | 1 |
| Duan, KM; Huang, Z; Ma, JH; Wang, SY; Yu, H; Zhou, Y | 1 |
| de Dios, I; Franco, S; Nieto, Y; Ortega, M; Rialp, G; Romero, M | 1 |
| Gibson, EL | 1 |
| Carvalho, AF; Geffard, M; Kanchanatawan, B; Maes, M; Sirivichayakul, S; Thika, S | 1 |
| Asakura, K; Kobayashi, S; Nojima, M; Sasaki, S; Suga, H | 1 |
| Barreto, FS; Chaves Filho, AJM; de Araújo, MCCR; de Lucena, DF; de Moraes, MEA; de Moraes, MO; Macedo, DS; Maes, M | 1 |
| Benoliel, JJ; Cipriani, A; Coghill, D; Cohen, D; Hetrick, SE; Jiang, X; Lan, X; Liu, L; Ravindran, AV; Xie, P; Yang, L; Yuan, S; Zhang, Y; Zheng, P; Zhou, X | 1 |
| Bengesser, SA; Birner, A; Dalkner, N; Fuchs, D; Gostner, JM; Hamm, C; Platzer, M; Reininghaus, B; Reininghaus, EZ; Riedrich, K | 1 |
| Carvalho, LA; Clarke, G; Díaz, LE; Gómez-Martínez, S; Marcos, A; Michels, N; Olavarria-Ramirez, L; Widhalm, K | 1 |
| Cui, T; Du, TT; Huang, D; Jiang, XH; Qiu, HM; Wang, NR | 1 |
| Deng, YT; Li, XH; Xu, TJ; Zhao, MG | 1 |
| Inglot, M; Laskus, T; Malyszczak, K; Pawlak, D; Pawlowski, T; Radkowski, M; Zalewska, M | 1 |
| Dantzer, R; Garcia, R; Kelley, KW; Lawson, M; McCusker, RH; Nixon, SE; O'Connor, JC; Rodriguez-Zas, SL; Romanova, EV; Southey, BR; Sweedler, JV; Wu, C; Zavala, C | 1 |
| Bansal, Y; Kuhad, A; Saroj, P; Singh, R; Sodhi, RK | 1 |
| Bengesser, S; Birner, A; Dalkner, N; Fellendorf, F; Gorkiewicz, G; Halwachs, B; Holl, AK; Holzer, P; Kapfhammer, HP; Kashofer, K; Moll, N; Mörkl, S; Painold, A; Platzer, M; Queissner, R; Reininghaus, EZ; Schütze, G; Schwarz, MJ | 1 |
| Gruenhage, F; Hahn, D; Kaiser, R; Lammert, F; Meyer, MR; Stokes, CS | 1 |
| Chen, L; Li, H; Li, M; Liu, W; Ning, Y; Wang, C; Zhan, Y; Zheng, W; Zhou, Y | 1 |
| Atzori, M; García-Oscos, F; Pérez-Padilla, EA; Pineda, JC; Ramírez, LA; Salgado, H | 1 |
| Chen, L; Li, H; Liu, W; Ning, Y; Wang, C; Zhan, Y; Zheng, W; Zhou, Y | 1 |
| Kanchanatawan, B; Maes, M; Sriswasdi, S | 1 |
| Geng, W; Pan, Y; Sun, Y; Wang, J; Wang, Y; Xiao, P | 1 |
| Beer, R; Ferger, B; Fuchs, D; Gaasch, M; Hackl, W; Helbok, R; Kofler, M; Pfausler, B; Rass, V; Rhomberg, P; Schiefecker, AJ; Schmutzhard, E; Sperner-Unterweger, B; Thomé, C | 1 |
| Hayakawa, K; Kanba, S; Kang, D; Kato, TA; Katsuki, R; Kubo, H; Kuwano, N; Sakamoto, S; Sato-Kasai, M; Setoyama, D; Shimokawa, N; Tateno, M; Teo, AR; Umene-Nakano, W; Watabe, M | 1 |
| Blauth, M; Fuchs, D; Hüfner, K; Sperner-Unterweger, B | 1 |
| Chang, WH; Chen, KC; Chen, PS; Chi, MH; Lee, IH; Lin, SH; Tsai, HC; Yang, YK | 1 |
| Chang, HS; Hu, KL; Li, LN; Lu, Y; Wang, PP; Yu, X; Zhang, B | 1 |
| Kubo, H; Morikawa, M; Mouri, A; Nabeshima, T; Nakamura, Y; Okada, T; Ozaki, N; Saito, K; Shiino, T; Teshigawara, T; Yamamoto, Y | 1 |
| Han, XM; Lu, YN; Qin, YJ; Rang, Y; Wang, NX; Zhai, XJ; Zhang, XL; Zhu, Y | 1 |
| Kasper, S | 1 |
| Cho, JH; Eisenberger, NI; Faull, K; Hwang, L; Irwin, MR; Kruse, JL; Olmstead, R | 1 |
| Young, SN | 1 |
| Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Rodriguez-Zas, SL | 1 |
| Arts, B; Guloksuz, S; Kenis, G; Russel, MG; van Os, J; Verkerk, R; Wauters, A; Wichers, M | 1 |
| Allen, PS; Grillon, C; Letkiewicz, A; Overstreet, C; Pine, DS; Robinson, OJ; Vytal, K | 1 |
| Anderson, G; Maes, M | 3 |
| Lee, H; Mikami, T; Ohno, M; Ohta, S | 1 |
| Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Parrott, JM | 1 |
| Boyle, NT; Collier, S; Connor, TJ; Harkin, A; Hevey, D; Hughes, MM; Kennedy, MJ; O'Dwyer, AM; Pertl, MM | 1 |
| Anderson, G; Berk, M; Maes, M | 3 |
| Bialonska, D; Lewellyn, K; Loria, MJ; Sufka, KJ; White, SW; Zjawiony, JK | 1 |
| Berthoz, S; Bioulac, S; Bouvard, M; Callebert, J; Delorme, M; Falissard, B; Gauthier, C; Gerardin, P; Godart, N; Hassler, C; Lang, F; Launay, JM; Mattar, L; Melchior, JC; Mourier-Soleillant, V; Pommereau, X; Steiger, H | 1 |
| Hennings, A; Rief, W; Riemer, S; Schwarz, MJ; Selberdinger, VB; Stapf, TM | 1 |
| Anderson, G; Berk, M; Dean, O; Maes, M; Moylan, S | 1 |
| Bangsberg, DR; Haberer, JE; Huang, Y; Hunt, PW; Kembabazi, A; Martin, JN; Martinez, P; Muzoora, C; Tsai, AC; Weiser, SD | 1 |
| Aguilera-Pérez, R; Flores-Ramos, M; Heinze, G; Moreno, J; Pellicer Graham, F | 1 |
| Botwinick, IC; Chabot, JA; Cooper, T; Mann, JJ; Pursell, L; Yu, G | 1 |
| André, C; Aubert, A; Castanon, N; Dinel, AL; Ferreira, G; Layé, S | 1 |
| Anderson, G; Berk, M; Kubera, M; Maes, M | 1 |
| Anderson, G; Berk, M; Duda, W; Kubera, M; Lasoń, W; Maes, M | 1 |
| Cai, L; Gao, L; He, Q; Liu, Y; Ren, Z; Xiao, L; Xie, W; Yu, Y | 1 |
| Amthor, KF; Ormstad, H; Sandvik, L; Verkerk, R | 1 |
| de Jonge, P; Doornbos, B; Duivis, HE; Kema, IP; Nolen, WA; Penninx, BW; Quak, J; Roest, AM; Vogelzangs, N | 1 |
| Furuse, M; Nagasawa, M; Ogino, Y; Otsuka, T; Tomonaga, S; Yasuo, S; Yoshida, J | 1 |
| Allison, DJ; Ditor, DS | 1 |
| Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK | 1 |
| Gibson, EL; Goralczyk, R; Hogan, E; Holmes, A; Mohajeri, MH; Rogers, PJ; Vargas, K; Wittwer, J | 1 |
| Bramness, JG; Hestad, K; Lien, L; Martinez, P; Neupane, SP | 1 |
| Budac, DP; Elfving, B; Eskelund, A; Fischer, CW; Liebenberg, N; Tillmann, S; Wegener, G | 1 |
| Anderson, G; Berk, M; Kanchanatawan, B; Maes, M; Martin-Subero, M | 1 |
| Furuse, M; Goda, R; Iwamoto, A; Kawai, M; Mizunoya, W; Oka, Y; Otsuka, T; Shibata, S; Yasuo, S | 1 |
| aan het Rot, M; Hogenelst, K; Kema, IP; Schoevers, RA; Sweep, FC | 1 |
| Fuchs, D; Gostner, JM; Strasser, B | 1 |
| Brandão, ML; Carabelli, B; Cunha, JM; Cunha, TM; da Silva Dias, IC; de Carvalho, MC; de Morais, H; Ferraz, AC; Ishii, DK; Rizzo de Souza, LE; Zanata, SM; Zanoveli, JM | 1 |
| aan het Rot, M; Hogenelst, K; Leander, NP; Müller, BC; Sarampalis, A; Schoevers, RA | 1 |
| Alyanakian, MA; Aouba, A; Bachmeyer, C; Barète, S; Bonin, B; Chandesris, MO; Chauvet-Gelinier, JC; Côté, F; Damaj, G; Dubreuil, P; Gaillard, R; Georgin-Lavialle, S; Grandpeix-Guyodo, C; Haffen, E; Hermine, O; Launay, JM; Lortholary, O; Moura, DS; Salvador, A; Soucié, E; Teyssier, JR; Trojak, B; Vandel, P | 1 |
| Cao, ZG; Liu, FF; Qin, XB; Zhou, LL | 1 |
| Antunes, MS; Boeira, SP; de Oliveira Espinosa, D; Donato, F; Giacomeli, R; Gomes, NS; Jesse, CR; Ruff, JR; Souza, LC | 1 |
| Dekker, FW; Franssen, CF; Haverkamp, GL; Honig, A; Kema, IP; Loosman, WL; Siegert, CE; van Diepen, M | 1 |
| Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Pokusa, M; Zorad, S | 1 |
| Carvalho, AF; Duleu, S; Geffard, M; Kanchanatawan, B; Maes, M; Roomruangwong, C; Sirivichayakul, S | 1 |
| Fujigaki, H; Imamura, Y; Ishibashi, T; Kim, HC; Kubo, H; Mamiya, T; Mitani, S; Murakami, Y; Nabeshima, T; Nishikawa, M; Ohta, Y; Saito, K; Takahashi, Y; Takakura, Y; Tashiro, T; Tomita, E; Watcharanurak, K; Yamamoto, Y | 1 |
| Guo, J; Han, JF; Pan, W; Sun, KJ; Wang, J; Xie, ZM; Yang, JJ; Zhang, GF | 1 |
| Banerjee, BD; Bhattacharya, SK; Deshmukh, P; Jain, S; Mediratta, PK; Rana, P; Sharma, AK | 1 |
| Hu, JQ; Hu, LJ; Huang, XN; Li, XF; Lin, CX; Lu, HY; Ni, XJ; Shang, DW; Wang, JJ; Wen, YG | 1 |
| Anderson, G; Berk, M; Carvalho, AF; Maes, M; Seo, M | 1 |
| Anderson, G; Rodriguez, M; Wootla, B | 1 |
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| Deutz, NE; Honig, A; Klaassen, T; Riedel, WJ; van Praag, HM; van Someren, A | 1 |
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| Bhatti, T; Clark, C; Gillin, JC; Kelsoe, J; Landolt, HP; Moore, P; Rapaport, M; Seifritz, E | 1 |
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| Annable, L; Chouinard, G; Sourkes, TL; Young, SN | 3 |
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| Costain, DW; Grahame-Smith, DG; Green, AR | 1 |
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| Annable, L; Chouinard, G; Kiriakos, RZ; Sourkes, TL; Young, SN | 1 |
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| Allgén, LG; Backman, L; Hallberg, D; Johansson, C; Thor'en, P | 1 |
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| Moody, JP; Naylor, G; Peet, M; Walker, P; Worrall, EP | 1 |
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| Birkmayer, W; Neumayer, E; Riederer, P | 1 |
| Henry, GM; Murphy, DL; Weingartner, H | 1 |
| Ashcroft, GW; Crawford, TB; Cundall, RL; Davidson, DL; Dobson, J; Dow, RC; Eccleston, D; Loose, RW; Pullar, IA | 1 |
| Frazer, A; Mendels, J; Pandey, GN | 1 |
| Allgén, LG; Hellström, L; Johansson, C | 1 |
| Fodor, A; Karczag, I; Molnár, G; Szilágyi, A; Ujvárosi, I | 1 |
| Brooksbank, BW; Coppen, A; Eccleston, E; Peet, M; White, SG | 1 |
| Ambrozi, L; Birkmayer, W; Neumayer, E; Riederer, P | 1 |
| Glassman, AH; Platman, SR | 1 |
| Korf, J; van Praag, HM; van Woudenberg, F | 1 |
| Scharfetter, C | 1 |
| Aliño, JJ; Ayuso Gutierrez, JL | 1 |
| Coppen, A; Noguera, R; Prange, AJ; Whybrow, PC | 1 |
| Rao, CK | 1 |
| McNamee, HB; Moody, JP; Naylor, GJ | 1 |
| Davis, JM; Forbes, DJ; Glisson, SN; Himwich, WA; Magnusson, T; Stout, MA; Trusty, DM | 1 |
| McLeod, MF; McLeod, WR | 1 |
| Coppen, AJ | 2 |
| Dewhurst, WG | 1 |
| Ashcroft, GW | 1 |
| Braham, J | 1 |
| Bridges, PK; Curzon, G | 1 |
| Birkmayer, W; Linauer, W | 1 |
| Allgén, LG | 1 |
| Birkmayer, W; Neumayer, E; Stöckl, W; Weiler, G | 1 |
| Mangoni, A | 1 |
| Leyton, GB | 1 |
| Gershon, ES; Shader, RI | 1 |
| Coppen, A; Eccleston, E; Gundy, G; Malleson, A; Shaw, DM | 1 |
104 review(s) available for tryptophan and Depression
| Article | Year |
|---|---|
Tryptophan: A Unique Role in the Critically Ill.
Topics: Critical Illness; Delirium; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Melatonin; Muscle, Skeletal; Sepsis; Serotonin; Tryptophan | 2021 |
The serotonin theory of depression: a systematic umbrella review of the evidence.
Topics: Antidepressive Agents; Depression; Humans; Hydroxyindoleacetic Acid; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan | 2023 |
Tryptophan Metabolism in Depression: A Narrative Review with a Focus on Serotonin and Kynurenine Pathways.
Topics: Depression; Humans; Kynurenine; Metabolic Networks and Pathways; Serotonin; Tryptophan | 2022 |
Neuroprotective Natural Products' Regulatory Effects on Depression via Gut-Brain Axis Targeting Tryptophan.
Topics: Biological Products; Brain-Gut Axis; Depression; Kynurenine; Neuroprotective Agents; Serotonin; Tryptophan | 2022 |
Role of gut microbiota in depression: Understanding molecular pathways, recent research, and future direction.
Topics: Depression; Gastrointestinal Microbiome; Histones; Humans; Kynurenine; Probiotics; RNA, Untranslated; Tryptophan | 2023 |
The role and mechanism of tryptophan - kynurenine metabolic pathway in depression.
Topics: Depression; Depressive Disorder, Major; Humans; Inflammation; Kynurenine; Metabolic Networks and Pathways; Tryptophan | 2023 |
The Interrelation between Oxidative Stress, Depression and Inflammation through the Kynurenine Pathway.
Topics: Cytokines; Depression; Humans; Inflammation; Kynurenine; Oxidative Stress; Tryptophan | 2023 |
Kynurenine pathway metabolites modulated the comorbidity of IBD and depressive symptoms through the immune response.
Topics: Colitis, Ulcerative; Comorbidity; Depression; Humans; Inflammation; Kynurenine; Tryptophan | 2023 |
The kynurenine pathway in major depressive disorder under different disease states: A systematic review and meta-analysis.
Topics: Biomarkers; Depression; Depressive Disorder, Major; Humans; Kynurenic Acid; Kynurenine; Quinolinic Acid; Tryptophan | 2023 |
Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer.
Topics: Anemia; Animals; Depression; Fatigue; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Neoplasms; Tryptophan | 2020 |
The Impact of Nutrition and Intestinal Microbiome on Elderly Depression-A Systematic Review.
Topics: Age Factors; Aged; Aged, 80 and over; Depression; Elder Nutritional Physiological Phenomena; Female; Gastrointestinal Microbiome; Humans; Male; Nutrition Therapy; Nutritional Status; Serotonin; Tryptophan; Vitamin B Complex | 2020 |
The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents.
Topics: Analgesics; Animals; Chronic Pain; Depression; Headache; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Kynurenine 3-Monooxygenase; Molecular Targeted Therapy; Neuralgia; Species Specificity; Tryptophan | 2020 |
Effect of immune activation on the kynurenine pathway and depression symptoms - A systematic review and meta-analysis.
Topics: Depression; Humans; Kynurenic Acid; Kynurenine; Prospective Studies; Tryptophan | 2020 |
Chronic fatigue and depression due to multiple sclerosis: Immune-inflammatory pathways, tryptophan catabolites and the gut-brain axis as possible shared pathways.
Topics: Brain; Depression; Fatigue Syndrome, Chronic; Humans; Multiple Sclerosis; Quality of Life; Tryptophan | 2020 |
A practical nutritional guide for the management of sleep disturbances in menopause.
Topics: Adult; Aged; Anxiety; Depression; Diet; Female; Humans; Male; Melatonin; Menopause; Middle Aged; Obesity; Sleep; Sleep Wake Disorders; Tryptophan | 2021 |
Inflammatory Depression-Mechanisms and Non-Pharmacological Interventions.
Topics: C-Reactive Protein; Depression; Depressive Disorder, Major; Dopaminergic Neurons; Dysbiosis; Exercise; Exercise Therapy; Fatty Acids, Omega-3; Gastrointestinal Microbiome; Humans; Inflammation; Probiotics; Synaptic Transmission; Tryptophan | 2021 |
Epilepsy Associated Depression: An Update on Current Scenario, Suggested Mechanisms, and Opportunities.
Topics: Animals; Anti-Inflammatory Agents; Central Nervous System Agents; Depression; Epilepsy; Humans; Hypothalamo-Hypophyseal System; Inflammation; Neurogenesis; Selective Serotonin Reuptake Inhibitors; Tryptophan | 2021 |
Tryptophan Catabolites in Bipolar Disorder: A Meta-Analysis.
Topics: Bipolar Disorder; Depression; Humans; Inflammation; Kynurenic Acid; Kynurenine; Tryptophan | 2021 |
Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease.
Topics: Animals; Brain-Gut Axis; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammatory Bowel Diseases; Kynurenine; Prognosis; Quality of Life; Quinolinic Acid; Signal Transduction; Tryptophan | 2021 |
IDO chronic immune activation and tryptophan metabolic pathway: A potential pathophysiological link between depression and obesity.
Topics: Depression; Humans; Immunity, Cellular; Indoleamine-Pyrrole 2,3,-Dioxygenase; Molecular Targeted Therapy; Obesity; Signal Transduction; Tryptophan | 2018 |
Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health.
Topics: Brain; Depression; Exercise; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Inflammation; Kynurenine; Liver; Mental Disorders; Mental Health; Muscle, Skeletal; Neoplasms; Signal Transduction; Tryptophan | 2017 |
The molecular aspects of oxidative & nitrosative stress and the tryptophan catabolites pathway (TRYCATs) as potential causes of depression.
Topics: Biomarkers; Depression; Humans; Nitrosative Stress; Oxidative Stress; Signal Transduction; Tryptophan | 2018 |
Inflammation-induced depression: Its pathophysiology and therapeutic implications.
Topics: Animals; Depression; Humans; Inflammation; Kynurenine; Serotonin; Tryptophan | 2017 |
Oxidative and Nitrosative Stress as Well as the Tryptophan Catabolites Pathway in Depressive Disorders.
Topics: Antidepressive Agents; Antioxidants; Biomarkers; Depression; Depressive Disorder; Disease Progression; Humans; Inflammation; Kynurenine; Metabolic Networks and Pathways; Nitric Oxide Synthase; Nitrosative Stress; Oxidative Stress; Quality of Life; Quinolinic Acid; Tryptophan | 2017 |
The role of tryptophan metabolism in postpartum depression.
Topics: Depression; Depression, Postpartum; Depressive Disorder, Major; Female; Humans; Kynurenine; Quinolinic Acid; Tryptophan | 2018 |
Tryptophan supplementation and serotonin function: genetic variations in behavioural effects.
Topics: Affect; Alleles; Behavior; Depression; Dietary Supplements; Female; Genetic Variation; Genotype; Humans; Hydrocortisone; Male; Receptors, Serotonin; Serotonin; Stress, Psychological; Tryptophan | 2018 |
Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer.
Topics: Animals; Depression; Depressive Disorder; Humans; Immunity; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Inflammation; Neoplasms; Oxidative Stress; Serotonin; Signal Transduction; Tryptophan | 2018 |
A new theory of depression based on the serotonin/kynurenine relationship and the hypothalamicpituitary- adrenal axis
Topics: Animals; Bacterial Infections; Brain; Cytokines; Depression; Humans; Hypothalamo-Hypophyseal System; Illness Behavior; Immunity, Innate; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interleukins; Kynurenine; Models, Neurological; Models, Psychological; Neuroglia; Peripheral Nervous System; Pituitary-Adrenal System; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Social Isolation; Stress, Psychological; Toll-Like Receptor 4; Tryptophan; Vaccines | 2018 |
The effect of raising and lowering tryptophan levels on human mood and social behaviour.
Topics: Affect; Aggression; Antidepressive Agents; Brain; Cognition; Depression; Humans; Interpersonal Relations; Recognition, Psychology; Serotonin; Social Behavior; Social Support; Tryptophan | 2013 |
TRYCAT pathways link peripheral inflammation, nicotine, somatization and depression in the etiology and course of Parkinson's disease.
Topics: Animals; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Nicotine; Parkinson Disease; Signal Transduction; Somatoform Disorders; Tryptophan | 2014 |
Biological phenotypes underpin the physio-somatic symptoms of somatization, depression, and chronic fatigue syndrome.
Topics: Autoimmunity; Biomarkers; Depression; Depressive Disorder, Major; Fatigue Syndrome, Chronic; Humans; Immunity, Cellular; Inflammation; Oxidative Stress; Phenotype; Signal Transduction; Somatoform Disorders; Tryptophan | 2014 |
Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins.
Topics: Animals; Brain; Depression; Humans; Lipid Peroxidation; Mitochondria; Nerve Degeneration; Oxidative Stress; Parkinson Disease; Sirtuins; Tryptophan | 2014 |
Role of immune-inflammatory and oxidative and nitrosative stress pathways in the etiology of depression: therapeutic implications.
Topics: Animals; Antidepressive Agents; Depression; Humans; Inflammation; Molecular Targeted Therapy; Oxidative Stress; Tryptophan | 2014 |
Oxidative/nitrosative stress and immuno-inflammatory pathways in depression: treatment implications.
Topics: Adaptive Immunity; Animals; Antioxidants; Apoptosis; Autoimmunity; Depression; Humans; Immunity, Cellular; Neurons; Nitrogen; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Tryptophan | 2014 |
Targeting classical IL-6 signalling or IL-6 trans-signalling in depression?
Topics: Acute-Phase Reaction; Animals; Antidepressive Agents; Autoimmunity; Bacterial Translocation; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Hypothalamo-Hypophyseal System; Inflammation; Interleukin-6; Meta-Analysis as Topic; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroimmunomodulation; Neurotransmitter Agents; Pituitary-Adrenal System; Receptors, Interleukin-6; Signal Transduction; Stress, Psychological; T-Lymphocyte Subsets; Tryptophan; Zinc | 2014 |
Increased IL-6 trans-signaling in depression: focus on the tryptophan catabolite pathway, melatonin and neuroprogression.
Topics: Animals; Depression; Humans; Inflammation; Interleukin-6; Receptors, Interleukin-6; Signal Transduction; Tryptophan | 2013 |
The common inflammatory etiology of depression and cognitive impairment: a therapeutic target.
Topics: Animals; Cognition Disorders; Depression; Humans; Inflammation; Kynurenine; Signal Transduction; Tryptophan | 2014 |
Comorbidity between depression and inflammatory bowel disease explained by immune-inflammatory, oxidative, and nitrosative stress; tryptophan catabolite; and gut-brain pathways.
Topics: Brain; Comorbidity; Depression; Depressive Disorder; Gastrointestinal Microbiome; Humans; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Nitrosation; Oxidative Stress; Stress, Physiological; Tryptophan | 2016 |
Mood, food, and cognition: role of tryptophan and serotonin.
Topics: Affect; Antioxidants; Brain; Cognition; Cognition Disorders; Depression; Diet; Feeding Behavior; Humans; Serotonin; Tryptophan | 2016 |
Gut Permeability and Microbiota in Parkinson's Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatonergic Pathways.
Topics: Depression; Gastrointestinal Microbiome; Humans; Inflammation; Intestinal Mucosa; Intestines; Melatonin; Nitrosative Stress; Oxidation-Reduction; Parkinson Disease; Permeability; Tryptophan | 2016 |
Multiple Sclerosis, Gut Microbiota and Permeability: Role of Tryptophan Catabolites, Depression and the Driving Down of Local Melatonin.
Topics: Animals; Depression; Gastrointestinal Microbiome; Humans; Melatonin; Multiple Sclerosis; Permeability; Tryptophan | 2016 |
Tryptophan Intake in the US Adult Population Is Not Related to Liver or Kidney Function but Is Associated with Depression and Sleep Outcomes.
Topics: Adult; Biomarkers; Depression; Female; Food Analysis; Humans; Kidney; Liver; Male; Nutrition Surveys; Sleep; Tryptophan; United States | 2016 |
The Microbiome-Gut-Brain Axis in Health and Disease.
Topics: Animals; Autistic Disorder; Brain; Cytokines; Depression; Fatty Acids, Volatile; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Parkinson Disease; Prebiotics; Probiotics; Tryptophan; Vagus Nerve | 2017 |
Serotonin and depression: pathophysiological mechanism or marketing myth?
Topics: Depression; Humans; Serotonin; Tryptophan | 2008 |
Neuropsychiatric disease and Toxoplasma gondii infection.
Topics: Animals; Behavior; Behavior, Animal; Cats; Cytokines; Depression; Dopamine; Female; Host-Parasite Interactions; Humans; Male; Mental Disorders; Mice; Nervous System Diseases; Neurons; Neurosecretory Systems; Protozoan Proteins; Rats; Risk Factors; Schizophrenia; Serotonin; Toxoplasma; Toxoplasmosis; Toxoplasmosis, Animal; Tryptophan | 2009 |
Major depressive disorder and nutritional medicine: a review of monotherapies and adjuvant treatments.
Topics: Amino Acids; Antidepressive Agents; Chemotherapy, Adjuvant; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Folic Acid; Humans; Nutritional Physiological Phenomena; Nutritional Status; S-Adenosylmethionine; Tryptophan | 2009 |
Neopterin, a prognostic marker in human malignancies.
Topics: Anemia; Biomarkers, Tumor; Cachexia; Cytokines; Depression; Fatigue; Humans; Neoplasms; Neopterin; Prognosis; Reactive Oxygen Species; Tryptophan; Weight Loss | 2010 |
Central fatigue: issues related to cognition, mood and behavior, and psychiatric diagnoses.
Topics: Affect; Cognition; Depression; Disorders of Excessive Somnolence; Fatigue; Humans; Multiple Sclerosis; Task Performance and Analysis; Tryptophan | 2010 |
Association between increased tryptophan degradation and depression in cancer patients.
Topics: Cytokines; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Neoplasms; Neurotoxins; Serotonin; Tryptophan | 2011 |
The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to th
Topics: Animals; Brain; Depression; Disease Models, Animal; Female; Humans; Immunity, Cellular; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Male; Nitrosation; Oxidative Stress; Serotonin; Tryptophan | 2011 |
Mood effects of the amino acids tryptophan and tyrosine: 'Food for Thought' III.
Topics: Antidepressive Agents; Biological Availability; Catecholamines; Clinical Trials as Topic; Depression; Humans; Mood Disorders; Neurotransmitter Agents; Nutritional Requirements; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine | 2011 |
Biological underpinnings of the commonalities in depression, somatization, and Chronic Fatigue Syndrome.
Topics: Cytokines; Depression; Fatigue Syndrome, Chronic; Humans; Immunity, Cellular; Inflammation; Models, Biological; Signal Transduction; Somatoform Disorders; Tryptophan | 2012 |
Inflammation-related disorders in the tryptophan catabolite pathway in depression and somatization.
Topics: Depression; Humans; Inflammation; Tryptophan | 2012 |
Kynurenines in cognitive functions: their possible role in depression.
Topics: Cognition; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Signal Transduction; Tryptophan | 2012 |
Review of the implications of dietary tryptophan intake in patients with irritable bowel syndrome and psychiatric disorders.
Topics: 5-Hydroxytryptophan; Depression; Diet; Digestive System; Humans; Irritable Bowel Syndrome; Molecular Structure; Serotonin; Tryptophan | 2003 |
Understanding emotion regulation in borderline personality disorder: contributions of neuroimaging.
Topics: Aspartic Acid; Borderline Personality Disorder; Brain; Brain Mapping; Choline; Compulsive Personality Disorder; Creatinine; Depression; Electroencephalography; Emotions; Female; Fenfluramine; Humans; Magnetic Resonance Imaging; Nerve Net; Serotonin Agents; Tomography, Emission-Computed; Tryptophan | 2003 |
Tryptophan depletion, serotonin, and depression: where do we stand?
Topics: Brain; Brain-Derived Neurotrophic Factor; Depression; Humans; Serotonin; Synapses; Tryptophan | 2003 |
Tryptophan modulation and cognition.
Topics: Cognition; Cognition Disorders; Depression; Humans; Models, Psychological; Serotonin; Tryptophan | 2003 |
[Influence of physical activity on mental well-being and psychiatric disorders].
Topics: Adolescent; Adult; Aged; Anxiety; beta-Endorphin; Child; Clinical Trials as Topic; Depression; Exercise; Exercise Therapy; Female; Humans; Male; Mental Disorders; Mental Health; Physical Endurance; Serotonin; Socioeconomic Factors; Sports; Time Factors; Tryptophan | 2004 |
Changes in the immune system in depression and dementia: causal or coincidental effects?
Topics: Cytokines; Dementia; Depression; Humans; Hypothalamo-Hypophyseal System; Immune System; Models, Biological; Pituitary-Adrenal System; Tryptophan | 2006 |
Antitumoral activity of interferon-gamma involved in impaired immune function in cancer patients.
Topics: Anemia; Cachexia; Cell Proliferation; Depression; Humans; Immunologic Deficiency Syndromes; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Neoplasms; Neopterin; Tryptophan; Tumor Escape | 2006 |
Sex differences in the effect of acute tryptophan depletion on declarative episodic memory: a pooled analysis of nine studies.
Topics: Adolescent; Adult; Affect; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Brain; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Male; Mental Recall; Middle Aged; Randomized Controlled Trials as Topic; Serotonin; Sex Factors; Tryptophan | 2007 |
A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression.
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Cytokines; Depression; Depressive Disorder, Major; Humans; Hypothalamo-Hypophyseal System; Kynurenine; Metabolic Networks and Pathways; Models, Biological; Pituitary-Adrenal System; Serotonin; Stress, Psychological; Tryptophan | 2008 |
Depression at the menopause.
Topics: Cultural Characteristics; Depression; Female; Humans; Menopause; Middle Aged; Social Adjustment; Tryptophan | 1984 |
Tyrosine for the treatment of depression.
Topics: 5-Hydroxytryptophan; Adult; Animals; Clinical Trials as Topic; Depression; Dihydroxyphenylalanine; Double-Blind Method; Female; Humans; Methoxyhydroxyphenylglycol; Tryptophan; Tyrosine | 1984 |
The eosinophilia-myalgia syndrome--guidelines for patient care.
Topics: Anxiety; Depression; Eosinophilia-Myalgia Syndrome; Glucocorticoids; Heart Diseases; Humans; Lung Diseases; Mental Processes; Neuromuscular Diseases; Practice Guidelines as Topic; Psychotherapy; Skin Diseases; Tryptophan | 1995 |
Non-nutritional uses of vitamin B6.
Topics: Animals; Carpal Tunnel Syndrome; Depression; Drug Interactions; Female; Glucose Tolerance Test; Homocysteine; Humans; Hypertension; Male; Nutrition Policy; Premenstrual Syndrome; Pyridoxine; Rats; Tryptophan | 1999 |
The effects of nutrients on mood.
Topics: Affect; Avitaminosis; Cacao; Depression; Diet; Humans; Iron Deficiencies; Micronutrients; Thiamine Deficiency; Tryptophan | 1999 |
Use of neurotransmitter precursors for treatment of depression.
Topics: 5-Hydroxytryptophan; Depression; Humans; Phenylalanine; Tryptophan; Tyrosine | 2000 |
Clinical and physiological consequences of rapid tryptophan depletion.
Topics: Antidepressive Agents; Depression; Female; Food, Formulated; Humans; Male; Neural Pathways; Neurons; Raphe Nuclei; Secondary Prevention; Serotonin; Tryptophan | 2000 |
Physiology and pathophysiology of the serotonergic system and its implications on mental and physical performance. Part I.
Topics: Autoreceptors; Biological Transport; Blood Platelets; Cell Membrane; Depression; Female; Humans; Lithium; Male; Mental Processes; Phosphatidylinositols; Presynaptic Terminals; Prolactin; Raphe Nuclei; Receptors, Serotonin; Second Messenger Systems; Secretory Vesicles; Serotonin; Suicide, Attempted; Tryptophan; Tryptophan Oxygenase | 2001 |
Tryptophan and 5-hydroxytryptophan for depression.
Topics: 5-Hydroxytryptophan; Antidepressive Agents, Second-Generation; Depression; Humans; Randomized Controlled Trials as Topic; Tryptophan | 2001 |
Tryptophan and 5-hydroxytryptophan for depression.
Topics: 5-Hydroxytryptophan; Antidepressive Agents, Second-Generation; Depression; Humans; Randomized Controlled Trials as Topic; Tryptophan | 2002 |
Neurochemical and neuropharmacological aspects of depression.
Topics: Addison Disease; Adrenal Cortex Hormones; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Cushing Syndrome; Cyclic AMP; Depression; Electroconvulsive Therapy; Humans; Lithium; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Reserpine; Tryptophan | 1975 |
The contribution of drug research to investigating the nature of endogenous depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Depression; Female; Fenclonine; Histamine H1 Antagonists; Humans; Mice; Neurotransmitter Agents; Norepinephrine; Reserpine; Serotonin; Structure-Activity Relationship; Tryptophan | 1976 |
Biochemistry of mental depression.
Topics: Age Factors; Bipolar Disorder; Blood Platelets; Brain; Catechol O-Methyltransferase; Depression; Dopamine; Female; Hormones; Humans; Male; Monoamine Oxidase; Neurotransmitter Agents; Norepinephrine; Serotonin; Sex Factors; Tryptophan | 1977 |
[Biochemistry of depression. Literature analysis].
Topics: Adrenal Cortex Hormones; Animals; Antidepressive Agents, Tricyclic; Brain; Depression; Dopamine; Humans; Lithium; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Norepinephrine; Probenecid; Reserpine; Serotonin; Synapses; Thyroid Hormones; Tryptophan; Water-Electrolyte Imbalance | 1978 |
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan | 1976 |
Theoretical and therapeutic potential of indoleamine precursors. (5).
Topics: 5-Hydroxytryptophan; Depression; Female; Humans; Serotonin; Tryptamines; Tryptophan | 1977 |
Psychoendocrinology.
Topics: Affective Symptoms; Depression; Endorphins; Growth Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Monoamine Oxidase; Pituitary-Adrenal System; Thyroid Gland; Thyroid Hormones; Tryptophan | 1979 |
[Therapeutically resistant depressive states].
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depersonalization; Depression; Drug Resistance; Electroconvulsive Therapy; Half-Life; Humans; Hypochondriasis; Levodopa; Middle Aged; Monoamine Oxidase Inhibitors; Sleep Deprivation; Syndrome; Thyrotropin; Tryptophan | 1979 |
[Catecholamines in the pathochemical structure of depressive conditions (according to material from a biological study)].
Topics: Adrenal Cortex Hormones; Adrenal Medulla; Animals; Brain; Catecholamines; Cell Nucleus; Depression; Disease Models, Animal; Dopamine; Epinephrine; Humans; Hypothalamus; Male; Norepinephrine; Psychopharmacology; Rats; Reserpine; RNA; Serotonin; Tryptophan | 1975 |
Effects of oral contraceptives on vitamin metabolism.
Topics: Ascorbic Acid; Blood Platelets; Contraceptives, Oral; Depression; Female; Folic Acid; Humans; Leukocytes; Menstruation; Nicotinic Acids; Pregnancy; Pyridoxine; Riboflavin; Serotonin; Thiamine; Time Factors; Tryptophan; Vitamin A; Vitamin B 12; Vitamin E; Vitamin E Deficiency; Vitamins | 1976 |
Metabolism of indole amines in depression.
Topics: Animals; Brain; Depression; Fatty Acids, Nonesterified; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Kynurenine; Male; Monoamine Oxidase Inhibitors; Rats; Serotonin; Tryptamines; Tryptophan | 1976 |
Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine.
Topics: Animals; Brain; Clomipramine; Depression; Dopamine; Humans; Hydroxyindoleacetic Acid; Lithium; Models, Biological; Monoamine Oxidase Inhibitors; Motor Activity; Phenytoin; Rats; Serotonin; Synapses; Thyrotropin-Releasing Hormone; Tryptophan | 1976 |
The possible role of thyroid and thyrotrophic hormones in depressive illness.
Topics: Depression; Electroconvulsive Therapy; Humans; Imipramine; Mental Status Schedule; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine; Tryptophan | 1976 |
Oral contraceptives and vitamins: a review.
Topics: Ascorbic Acid; Contraceptives, Oral; Depression; Estradiol Congeners; Female; Folic Acid; Folic Acid Deficiency; Humans; Lipids; Menstruation; Nicotinic Acids; Pyridoxine; Tryptophan; Vitamin A; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins | 1975 |
Tryptophan, depression and steroidal contraception.
Topics: Brain; Contraceptives, Oral; Contraceptives, Oral, Combined; Depression; Female; Humans; Pyridoxine; Time Factors; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Disturbances in tryptophan and serotonin metabolism in affective psychoses and schizophrenia.
Topics: Affective Symptoms; Depression; Humans; Psychotic Disorders; Schizophrenia; Serotonin; Tryptophan | 1975 |
Neuroendocrine challenge tests: assessment of 5-HT function in anxiety and depression.
Topics: Anxiety; Depression; Humans; Neurosecretory Systems; Obsessive-Compulsive Disorder; Panic Disorder; Serotonin; Synapses; Tryptophan | 1992 |
Role of serotonin in depression.
Topics: Affect; Blood Platelets; Depression; Depressive Disorder; Humans; Serotonin; Suicide; Tryptophan | 1990 |
Drug-induced depression and tryptophan metabolism.
Topics: Adrenocorticotropic Hormone; Contraceptives, Oral; Cortisone; Depression; Estrogens; Female; Humans; Male; Pregnancy; Psychoses, Substance-Induced; Reserpine; Serotonin; Tryptophan | 1972 |
Biochemistry of depression (a review of the literature).
Topics: Adrenal Glands; Amines; Biogenic Amines; Brain Chemistry; Carbohydrate Metabolism; Catecholamines; Circadian Rhythm; Depression; Hormones; Humans; Imipramine; Lipid Metabolism; Lithium; Monoamine Oxidase Inhibitors; Phenothiazines; Reserpine; Synaptic Transmission; Thyroid Gland; Tryptophan; Water-Electrolyte Balance | 1971 |
The pharmacodynamics of depression and its relation to therapy.
Topics: Adrenal Glands; Amitriptyline; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain Chemistry; Cyclic AMP; Depression; Dextroamphetamine; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Iproniazid; Lithium; Norepinephrine; Postpartum Period; Potassium; Pregnancy; Reaction Time; Serotonin; Sodium; Tryptophan | 1974 |
Psychochemical research studies in man.
Topics: Animals; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Depression; Dihydroxyphenylalanine; Hallucinogens; Hartnup Disease; Humans; Imipramine; Metabolism, Inborn Errors; Models, Neurological; Neurons; Neurotransmitter Agents; Norepinephrine; Phenylketonurias; Psychopharmacology; Sleep, REM; Tryptophan | 1968 |
Aspects of tryptophan metabolism in health and disease: a review.
Topics: Brain; Breast Neoplasms; Contraceptives, Oral; Depression; Endocrine System Diseases; Female; Glucocorticoids; Humans; Kidney Neoplasms; Male; Nicotinic Acids; Prostatic Neoplasms; Pyridoxine; Ribonucleotides; Serotonin; Tryptophan; Urinary Bladder Neoplasms; Vitamin B 6 Deficiency | 1972 |
[Biochemistry of depression].
Topics: Animals; Bipolar Disorder; Brain; Central Nervous System; Depression; Dihydroxyphenylalanine; Glycols; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Parkinson Disease; Peripheral Nerves; Phenylacetates; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1972 |
Psychopharmacology. Yesterday, today and tomorrow: a point of view.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Canada; Carbonates; Depression; Dihydroxyphenylalanine; Drug Industry; Electroconvulsive Therapy; Humans; Imipramine; Lithium; Mental Disorders; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Nicotinic Acids; Psychopharmacology; Research Support as Topic; Schizophrenia; Tranquilizing Agents; Tryptophan; Vitamins | 1973 |
Melancholia, a model in madness: a discussion of recent psychobiologic research into depressive illness.
Topics: Adaptation, Psychological; Biogenic Amines; Brain; Depression; Dihydroxyphenylalanine; Emotions; Environment; Homeostasis; Humans; Hydroxyindoleacetic Acid; Models, Biological; Models, Psychological; Research; Stress, Psychological; Terminology as Topic; Tryptophan | 1973 |
Research report: Institute of Psychiatry Clinical Psychopharmacology Research Team.
Topics: Antidepressive Agents; Anxiety; Barbiturates; Conversion Disorder; Depression; Drug Combinations; Drug Interactions; Electroencephalography; Humans; Hypnotics and Sedatives; Imipramine; Nitrous Oxide; Psychopharmacology; Psychophysiology; Research; Research Design; Sweat Glands; Tranquilizing Agents; Tryptophan | 1974 |
[Oral contraceptives and vitamins].
Topics: Animals; Ascorbic Acid; Blood Glucose; Contraceptives, Oral; Depression; Depression, Chemical; Estrogens; Female; Folic Acid; Humans; Pregnancy; Pyridoxine; Rats; Tryptophan; Vitamin A; Vitamin B 12 | 1974 |
Kynurenines as probable participants of depression.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior; Blood Pressure; Body Temperature; Depression; Dopamine; Drug Interactions; Drug Synergism; Humans; Kynurenine; Mice; Motor Activity; Norepinephrine; ortho-Aminobenzoates; Rats; Serotonin; Serotonin Antagonists; Species Specificity; Sympathetic Nervous System; Tryptamines; Tryptophan | 1973 |
Tryptophan pyrrolase--a biochemical factor in depressive illness?
Topics: Animals; Brain; Cats; Depression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Pituitary-Adrenal System; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1969 |
[Recent research in the field of affective psychoses, particularly depressions].
Topics: Adolescent; Adult; Age Factors; Bipolar Disorder; Catecholamines; Depression; Female; Humans; Lithium; Male; Middle Aged; Prognosis; Seasons; Serotonin; Sex Factors; Tryptophan | 1971 |
96 trial(s) available for tryptophan and Depression
| Article | Year |
|---|---|
Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial.
Topics: Animals; Bifidobacterium breve; Depression; Depressive Disorder, Major; Double-Blind Method; Gastrointestinal Microbiome; Humans; Mice; Treatment Outcome; Tryptophan | 2022 |
Effect of Tryptophan, Vitamin B
Topics: Adolescent; Adult; Affect; Depression; Dietary Supplements; Double-Blind Method; Female; Heart Rate; Humans; Male; Niacinamide; Placebos; Tryptophan; Vitamin B 6; Young Adult | 2019 |
SLC6A4 polymorphisms modulate the efficacy of a tryptophan-enriched diet on age-related depression and social cognition.
Topics: Age Factors; Alleles; Depression; Diet; Diet Surveys; Eating; Empathy; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Healthy Volunteers; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nutritional Physiological Phenomena; Polymorphism, Genetic; Psychological Tests; Serotonin Plasma Membrane Transport Proteins; Single-Blind Method; Social Cognition; Tryptophan; Young Adult | 2021 |
Kynurenine metabolism and inflammation-induced depressed mood: A human experimental study.
Topics: Adult; Affect; Cytokines; Depression; Endotoxins; Female; Humans; Inflammation; Interleukin-6; Kynurenic Acid; Kynurenine; Male; Middle Aged; Quinolinic Acid; Sex Factors; Tryptophan; Tumor Necrosis Factor-alpha | 2019 |
The role of serotonin in the neurocircuitry of negative affective bias: serotonergic modulation of the dorsal medial prefrontal-amygdala 'aversive amplification' circuit.
Topics: Adult; Affect; Affective Symptoms; Amygdala; Anxiety; Bias; Cross-Over Studies; Depression; Double-Blind Method; Emotions; Female; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Neural Pathways; Prefrontal Cortex; Serotonin; Serotonin Receptor Agonists; Tryptophan | 2013 |
Chronic treatment with a tryptophan-rich protein hydrolysate improves emotional processing, mental energy levels and reaction time in middle-aged women.
Topics: Aged; Antidepressive Agents; Beverages; Cognitive Dysfunction; Cohort Studies; Depression; Dietary Supplements; Double-Blind Method; Egg Proteins, Dietary; Energy Metabolism; Female; Humans; Mental Fatigue; Middle Aged; Nootropic Agents; Protein Hydrolysates; Psychiatric Status Rating Scales; Reaction Time; Serotonin Agents; Sleep Wake Disorders; Stress, Psychological; Tryptophan | 2015 |
Empathic accuracy and oxytocin after tryptophan depletion in adults at risk for depression.
Topics: Adult; Affect; Brain; Cross-Over Studies; Depression; Double-Blind Method; Emotions; Empathy; Female; Humans; Male; Oxytocin; Risk Factors; Serotonin; Tryptophan; Young Adult | 2016 |
The effects of acute tryptophan depletion on speech and behavioural mimicry in individuals at familial risk for depression.
Topics: Adult; Behavior; Brain; Cross-Over Studies; Depression; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Interpersonal Relations; Male; Serotonin; Social Behavior; Speech; Tryptophan; Young Adult | 2016 |
Serotonin transporter genotype and depressive phenotype determination by discriminant analysis of glucose metabolism under acute tryptophan depletion.
Topics: Adult; Brain; Depression; Discriminant Analysis; Female; Fluorodeoxyglucose F18; Genetic Predisposition to Disease; Glucose; Humans; Male; Phenotype; Placebo Effect; Positron-Emission Tomography; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins; Tryptophan | 2008 |
Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression.
Topics: Affect; Analysis of Variance; Cognition; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Neuropsychological Tests; Protein Hydrolysates; Saliva; Serotonin; Stress, Psychological; Tryptophan; Young Adult | 2009 |
Acute tryptophan depletion evokes negative mood in healthy females who have previously experienced concurrent negative mood and tryptophan depletion.
Topics: Affect; Analysis of Variance; Association Learning; Beverages; Depression; Female; Humans; Pain Measurement; Psychiatric Status Rating Scales; Time Factors; Tryptophan | 2009 |
The effects of tryptophan depletion on neural responses to emotional words in remitted depression.
Topics: Adolescent; Adult; Brain; Cross-Over Studies; Depression; Double-Blind Method; Emotions; Female; Humans; Male; Middle Aged; Neurons; Placebos; Psychomotor Performance; Regional Blood Flow; Remission, Spontaneous; Serotonin; Tryptophan | 2009 |
The effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly.
Topics: Affect; Age Factors; Aged; Antiparkinson Agents; Cross-Over Studies; Depression; Double-Blind Method; Humans; Middle Aged; Parkinson Disease; Placebo Effect; Psychiatric Status Rating Scales; Serotonin; Severity of Illness Index; Tryptophan | 2010 |
Effect of tryptophan-rich egg protein hydrolysate on brain tryptophan availability, stress and performance.
Topics: Affect; Amino Acids; Brain; Cross-Over Studies; Depression; Dietary Proteins; Double-Blind Method; Eggs; Female; Food, Fortified; Humans; Male; Protein Hydrolysates; Psychomotor Performance; Serotonin; Stress, Psychological; Tryptophan | 2010 |
Electrocortical effects of acute tryptophan depletion on emotive facial processing in depression-prone individuals.
Topics: Adult; Analysis of Variance; Cerebral Cortex; Depression; Double-Blind Method; Electroencephalography; Emotions; Evoked Potentials, Visual; Face; Facial Expression; Female; Follow-Up Studies; Humans; Male; Neuropsychological Tests; Pattern Recognition, Visual; Photic Stimulation; Reaction Time; Recognition, Psychology; Tryptophan | 2010 |
Effect of acute tryptophan depletion on emotions in individuals with personal and family history of depression following a mood induction.
Topics: Adult; Affect; Depression; Double-Blind Method; Emotions; Family Health; Female; Humans; Male; Placebos; Stress, Psychological; Time Factors; Tryptophan | 2010 |
Influence of acute tryptophan depletion on gastric sensorimotor function in humans.
Topics: Adult; Anxiety; Compliance; Depression; Diagnostic Techniques, Digestive System; Double-Blind Method; Dyspepsia; Eating; Female; Gastric Mucosa; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Intestinal Mucosa; Male; Sensation; Serotonin; Stomach; Time Factors; Tryptophan | 2011 |
Emotional processing as a predictor of symptom change: an acute tryptophan depletion study in depressed patients.
Topics: Adolescent; Adult; Aged; Cognition Disorders; Depression; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Humans; Mental Recall; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Reaction Time; Time Factors; Tryptophan; Young Adult | 2011 |
Time series fMRI measures detect changes in pontine raphé following acute tryptophan depletion.
Topics: Adolescent; Adult; Cross-Over Studies; Depression; Diet; Double-Blind Method; Electroencephalography; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Oxygen; Pons; Retrospective Studies; Statistics as Topic; Time Factors; Tryptophan; Wavelet Analysis; Young Adult | 2011 |
The effects of acute tryptophan depletion on costly information sampling: impulsivity or aversive processing?
Topics: Adult; Amino Acids; Anxiety; Decision Making; Depression; Female; Humans; Impulsive Behavior; Mental Processes; Psychomotor Performance; Self Report; Tryptophan | 2012 |
Neural expression of nicotine's antidepressant properties during tryptophan depletion: an EEG study in healthy volunteers at risk for depression.
Topics: Administration, Cutaneous; Affect; Alpha Rhythm; Antidepressive Agents; Brain Mapping; Cerebral Cortex; Depression; Double-Blind Method; Electroencephalography; Female; Humans; Male; Nicotine; Nicotinic Agonists; Tryptophan | 2012 |
Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation.
Topics: Adult; Anxiety; Depression; Female; Humans; Immunity; Inflammation; Interleukin-6; Interleukin-8; Kynurenine; Leukemia Inhibitory Factor Receptor alpha Subunit; Menstrual Cycle; Postpartum Period; Pregnancy; Psychiatric Status Rating Scales; Receptors, Cytokine; Receptors, OSM-LIF; Tryptophan | 2002 |
The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers.
Topics: Adult; Affect; Cognition; Cross-Over Studies; Depression; Discrimination, Psychological; Double-Blind Method; Emotions; Female; Humans; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Serotonin; Social Perception; Tryptophan | 2002 |
Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Double-Blind Method; Female; Humans; Interferon-alpha; Kynurenine; Male; Melanoma; Middle Aged; Neopterin; Paroxetine; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan | 2003 |
IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity.
Topics: Adult; Depression; Dioxygenases; Female; Follow-Up Studies; Hepatitis C, Chronic; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 2005 |
Affective state and EEG sleep profile in response to rapid tryptophan depletion in recently recovered nonmedicated depressed individuals.
Topics: Adult; Affect; Brain; Cognitive Behavioral Therapy; Depression; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Personality Inventory; Recurrence; Serotonin; Sleep, REM; Treatment Outcome; Tryptophan | 2004 |
Serotonergic modulation of mismatch negativity.
Topics: Adult; Affect; Amino Acid Transport System L; Attention; Auditory Perception; Cognition; Cross-Over Studies; Depression; Double-Blind Method; Electroencephalography; Electromagnetic Fields; Evoked Potentials; Female; Humans; Magnetoencephalography; Male; Serotonin; Signal Detection, Psychological; Tryptophan | 2005 |
Low-dose tryptophan depletion in recovered depressed patients induces changes in cognitive processing without depressive symptoms.
Topics: Adult; Amino Acids; Brain Chemistry; Case-Control Studies; Chromatography, High Pressure Liquid; Cognition; Depression; Diet, Protein-Restricted; Electromyography; Emotions; Facial Expression; Female; Humans; Male; Memory; Pain Measurement; Psychiatric Status Rating Scales; Psychological Tests; Reflex, Startle; Tryptophan; Verbal Learning | 2005 |
The effects of a diet enriched with alpha-lactalbumin on mood and cortisol response in unmedicated recovered depressed subjects and controls.
Topics: Adult; Affect; Amino Acids; Analysis of Variance; Case-Control Studies; Cross-Over Studies; Depression; Diet; Dietary Supplements; Double-Blind Method; Female; Humans; Hydrocortisone; Lactalbumin; Male; Saliva; Statistics, Nonparametric; Tryptophan | 2005 |
Selective processing of social threat cues following acute tryptophan depletion.
Topics: Adult; Affect; Amino Acids; Antidepressive Agents; Attention; Color Perception; Cues; Depression; Female; Humans; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Social Environment; Social Perception; Surveys and Questionnaires; Tryptophan | 2006 |
A pattern of antidepressive effect of tryptophan & imipramine in males & females.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Sex Characteristics; Treatment Outcome; Tryptophan | 1974 |
Effects of tryptophan depletion on cognitive functioning, obsessive-compulsive symptoms and mood in obsessive-compulsive disorder: preliminary results.
Topics: Adult; Affect; Anxiety; Cognition; Cross-Over Studies; Depression; Double-Blind Method; Female; Food, Formulated; Humans; Male; Neuropsychological Tests; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Tryptophan | 2007 |
Tyrosine for the treatment of depression.
Topics: 5-Hydroxytryptophan; Adult; Animals; Clinical Trials as Topic; Depression; Dihydroxyphenylalanine; Double-Blind Method; Female; Humans; Methoxyhydroxyphenylglycol; Tryptophan; Tyrosine | 1984 |
Potentiation of the effect of antidepressant drugs by tryptophan.
Topics: Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergism; Humans; Pyridines; Sleep Wake Disorders; Tryptophan; Zimeldine | 1980 |
Decrease in circulating tryptophan availability to the brain after acute ethanol consumption by normal volunteers: implications for alcohol-induced aggressive behaviour and depression.
Topics: Adult; Aggression; Amino Acids; Brain Chemistry; Central Nervous System Depressants; Depression; Ethanol; Humans; Male; Tryptophan | 1995 |
Acute dietary tryptophan depletion: effects on schizophrenic positive and negative symptoms.
Topics: Adult; Brain; Cross-Over Studies; Delusions; Depression; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan | 1997 |
Effects of tryptophan depletion in fully remitted patients with seasonal affective disorder during summer.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Male; Seasonal Affective Disorder; Seasons; Tryptophan | 1998 |
A placebo-controlled clinical trial of L-tryptophan in premenstrual dysphoria.
Topics: Adult; Affective Symptoms; Analysis of Variance; Antidepressive Agents, Second-Generation; Depression; Dizziness; Double-Blind Method; Female; Humans; Irritable Mood; Placebos; Premenstrual Syndrome; Quality of Life; Serotonin Agents; Treatment Outcome; Tryptophan | 1999 |
Specificity of the tryptophan depletion method.
Topics: Adolescent; Adult; Affect; Aged; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Lysine; Male; Memory; Middle Aged; Neuropsychology; Surveys and Questionnaires; Tryptophan; Verbal Learning | 1999 |
Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders.
Topics: Adolescent; Cross-Over Studies; Depression; Double-Blind Method; Family; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mood Disorders; Psychiatric Status Rating Scales; Reference Values; Sex Characteristics; Tryptophan | 1999 |
Tryptophan depletion and depressive vulnerability.
Topics: Adult; Aged; Biomarkers; Cross-Over Studies; Depression; Double-Blind Method; Female; Genetic Predisposition to Disease; Humans; Male; Mood Disorders; Psychiatric Status Rating Scales; Recurrence; Serotonin; Sex Characteristics; Tryptophan | 1999 |
Plasma tryptophan and trait aggression.
Topics: Adult; Aggression; Anxiety; Depression; Hostility; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 1999 |
Tryptophan enhancement/depletion and reactions to failure on a cooperative computer game.
Topics: Adult; Affect; Aggression; Analysis of Variance; Anger; Anxiety; Blood Pressure; Depression; Double-Blind Method; Emotions; Hostility; Humans; Male; Play and Playthings; Tryptophan | 1999 |
Fructose- and sorbitol-reduced diet improves mood and gastrointestinal disturbances in fructose malabsorbers.
Topics: Adolescent; Adult; Affect; Aged; Breath Tests; Colonic Diseases, Functional; Depression; Digestive System; Female; Fructose; Fructose Intolerance; Humans; Hydrogen; Male; Middle Aged; Quality of Life; Sorbitol; Tryptophan | 2000 |
Mood congruent memory bias induced by tryptophan depletion.
Topics: Adolescent; Adult; Depression; Female; Humans; Male; Memory; Middle Aged; Mood Disorders; Tryptophan | 2002 |
Letter: Potentiation of antidepressant action of clomipramine by tryptophan.
Topics: Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Drug Synergism; Drug Therapy, Combination; Humans; Male; Tryptophan | 1975 |
Letter: Treatment of unipolar depression.
Topics: Depression; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Niacinamide; Tryptophan | 1975 |
Letter: Tryptophan/imipramine in depression.
Topics: Adult; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Tryptophan | 1975 |
Letter: Treatment of unpolar depression.
Topics: Ascorbic Acid; Depression; Drug Therapy, Combination; Humans; Pyridoxine; Tryptophan | 1976 |
Tryptophan-nicotinamide combination in depression.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Niacinamide; Tryptophan | 1977 |
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan | 1976 |
Tryptophan dosage critical for its antidepressant effect.
Topics: Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergism; Humans; Imipramine; Niacinamide; Tryptophan | 1978 |
Tryptophan-nicotinamide, imipramine and their combination in depression. A controlled study.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Kynurenine; Male; Middle Aged; Niacinamide; Psychiatric Status Rating Scales; Tryptophan | 1979 |
Tryptophan and depressive illness.
Topics: Blood Proteins; Clinical Trials as Topic; Clofibrate; Depression; Dietary Proteins; Double-Blind Method; Estrogens, Conjugated (USP); Fatty Acids, Nonesterified; Female; Humans; Menopause; Middle Aged; Protein Binding; Tryptophan | 1978 |
S-tryptophan concentrations after intestinal bypass in extreme obesity.
Topics: Administration, Oral; Amino Acids; Anxiety; Body Weight; Clinical Trials as Topic; Depression; Humans; Intestine, Small; Jejunum; Liver; Obesity; Placebos; Postoperative Complications; Serum Albumin; Tryptophan; Water-Electrolyte Imbalance | 1977 |
Studies of endocrine activity, plasma tryptophan and catecholamine excretion on psychosurgical patients.
Topics: Adult; Anxiety; Clinical Trials as Topic; Depression; Dexamethasone; Epinephrine; Female; Humans; Hydrocortisone; Middle Aged; Norepinephrine; Obsessive-Compulsive Disorder; Personality Inventory; Psychosurgery; Tryptophan | 1977 |
Evaluation of the combination of tryptophan and ECT in the treatment of depression. II. Biochemical analysis.
Topics: Administration, Oral; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Evaluation Studies as Topic; Female; Humans; Male; Psychiatric Status Rating Scales; Sex Factors; Tryptophan | 1977 |
Evaluation of the combination of tryptophan and ECT in the treatment of depression. I. Clinical analysis.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Combinations; Electroconvulsive Therapy; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales; Time Factors; Tryptophan | 1977 |
L-tryptophan and 5-hydroxytryptophan in the treatment of depression. A review.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Placebos; Tryptophan | 1978 |
Influence of tryptophan on memory functions in depressive patients treated with unilateral ECT.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Electroconvulsive Therapy; Female; Humans; Male; Memory; Middle Aged; Placebos; Tryptophan | 1978 |
Addition of L-tryptophan to electroconvulsive treatment in endogenous depression. A double-blind study.
Topics: Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Tryptophan | 1978 |
Controlled studies of the acute antidepressant effects of lithium.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Combinations; Female; Humans; Imipramine; Lithium; Middle Aged; Random Allocation; Tryptophan | 1979 |
Symptom reduction in depression after treatment with L-tryptophan or imipramine. Item analysis of Hamilton rating scale for depression.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors; Tryptophan | 1979 |
L-tryptophan for treatment of depression?
Topics: Clinical Trials as Topic; Depression; Humans; Tryptophan | 1979 |
Psychomotor skills in depressed out-patients treated with L-tryptophan, doxepin, or chlorimipramine.
Topics: Adult; Attention; Clomipramine; Depression; Dibenzazepines; Doxepin; Female; Humans; Male; Middle Aged; Motor Skills; Proprioception; Tryptophan | 1978 |
Editorial: Tryptophan and depression.
Topics: Clinical Trials as Topic; Depression; Drug Therapy, Combination; Humans; Tryptophan | 1976 |
Letter: Tryptophan and depression.
Topics: Clinical Trials as Topic; Depression; Humans; Imipramine; Tryptophan | 1976 |
L-tryptophan in depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Biological Transport, Active; Bipolar Disorder; Clinical Trials as Topic; Depression; Female; Humans; Lithium; Male; Middle Aged; Monoamine Oxidase Inhibitors; Phenelzine; Placebos; Psychiatric Status Rating Scales; Time Factors; Tranylcypromine; Tryptophan | 1976 |
Tryptophan, 5-hydroxytryptophan and tricyclic antidepressants in the treatment of depression.
Topics: 5-Hydroxytryptophan; Catecholamines; Clinical Trials as Topic; Clomipramine; Depression; Depression, Chemical; Dibenzazepines; Female; Humans; Placebos; Psychiatric Status Rating Scales; Receptors, Serotonin; Suicide; Tryptophan | 1976 |
Comparative trial of L-tryptophan and amitriptyline in depressive illness.
Topics: Adult; Aged; Ambulatory Care; Amitriptyline; Antidepressive Agents; Anxiety; Blood Chemical Analysis; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors; Tryptophan | 1976 |
Potentiation of the antidepressant action of clomipramine by tryptophan.
Topics: Adolescent; Adult; Aged; Anxiety; Clomipramine; Depression; Dibenzazepines; Drug Synergism; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Placebos; Psychomotor Disorders; Time Factors; Tryptophan | 1976 |
Affective disorder: studies with amine precursors.
Topics: Adult; Antidepressive Agents; Biogenic Amines; Bipolar Disorder; Brain; Brain Chemistry; Clinical Trials as Topic; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Models, Biological; Placebos; Remission, Spontaneous; Tryptophan | 1975 |
Amine precursors and depression.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Humans; Levodopa; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Recurrence; Tryptophan | 1975 |
Tricyclic antidepressants and tryptophan in unipolar depression.
Topics: Clomipramine; Depression; Desipramine; Dibenzazepines; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Placebos; Receptors, Adrenergic; Serotonin; Tryptophan | 1975 |
Tryptophan depletion causes a rapid lowering of mood in normal males.
Topics: Adolescent; Adult; Amino Acids; Attention; Depression; Emotions; Humans; Male; Serotonin; Tryptophan | 1985 |
Tryptophan concentration in the cerebrospinal fluid of depressive patients.
Topics: Adult; Aged; Biological Transport; Bipolar Disorder; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Tryptophan | 1972 |
Tricyclic antidepressants and tryptophan in unipolar affective disorder.
Topics: Affective Symptoms; Antidepressive Agents; Depression; Desipramine; Evaluation Studies as Topic; Humans; Tryptophan | 1972 |
Effect of pyridoxine hydrochloride (vitamin B 6 ) upon depression associated with oral contraception.
Topics: Adult; Amines; Brain; Clinical Trials as Topic; Contraceptives, Oral; Depression; Erythrocytes; Estrogens; Female; Humans; Libido; Liver; Placebos; Progestins; Pyridoxine; Time Factors; Transaminases; Tryptophan; Tryptophan Oxygenase | 1973 |
Plasma-tryptophan levels in depression.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Depression; Humans; Tryptophan | 1973 |
Levodopa and L-tryptophan therapy in Parkinsonism.
Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Gait; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nausea; Occupational Therapy; Parkinson Disease; Personality Inventory; Physical Therapy Modalities; Posture; Psychiatric Status Rating Scales; Spasm; Speech Therapy; Tremor; Tryptophan | 1972 |
Letter: Tryptophan in depression.
Topics: Clinical Trials as Topic; Depression; Drug Synergism; Humans; Imipramine; Monoamine Oxidase Inhibitors; Tryptophan | 1974 |
Letter: Tryptophan in depression.
Topics: Clinical Trials as Topic; Depression; Drug Synergism; Electroconvulsive Therapy; Humans; Monoamine Oxidase Inhibitors; Tryptophan | 1974 |
Sequential comparison of L-tryptophan with E.C.T. in severe depression.
Topics: Aged; Depression; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Tryptophan | 1970 |
L-tryptophan in depression.
Topics: Clinical Trials as Topic; Depression; Humans; Monoamine Oxidase Inhibitors; Tryptophan | 1970 |
L-tryptophan in depression.
Topics: Depression; Electroconvulsive Therapy; Humans; Tryptophan | 1970 |
Comparable therapeutic efficacy of tryptophan and imipramine: average therapeutic ratings versus "true" equivalence. An important difference.
Topics: Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Humans; Imipramine; Psychiatric Status Rating Scales; Statistics as Topic; Terminology as Topic; Therapeutic Equivalency; Tryptophan | 1973 |
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Phenylacetates; Placebos; Probenecid; Stimulation, Chemical; Substance-Related Disorders; Tryptophan | 1974 |
The comparative antidepressant value of L-tryptophan and imipramine with and without attempted potentiation by liothyronine.
Topics: Clinical Trials as Topic; Depression; Drug Combinations; Drug Synergism; Evaluation Studies as Topic; Female; Humans; Imipramine; Interview, Psychological; Male; Middle Aged; Placebos; Prognosis; Psychiatric Status Rating Scales; Psychological Tests; Sex Factors; Triiodothyronine; Tryptophan | 1972 |
Thyroid function and the response to liothyronine in depression.
Topics: Ankle; Cholesterol; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Female; Humans; Imipramine; Male; Middle Aged; Prognosis; Reaction Time; Reflex; Sex Factors; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronine; Tryptophan | 1972 |
Effect of L-tryptophan on brain serotonin metabolism in depressed patients.
Topics: Brain; Brain Chemistry; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Humans; Hydroxyindoleacetic Acid; Placebos; Probenecid; Serotonin; Spinal Puncture; Tryptophan | 1972 |
L-tryptophan in mania. Contribution to a permissive hypothesis of affective disorders.
Topics: Adult; Affective Symptoms; Amines; Bipolar Disorder; Brain; Catecholamines; Chlorpromazine; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Indoles; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Remission, Spontaneous; Tryptophan | 1974 |
Amitriptyline in man: decreased formation of central 5-hydroxyindoleacetic acid.
Topics: Aged; Amitriptyline; Clinical Trials as Topic; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Serotonin; Tryptophan | 1974 |
L-tryptophan in affective disorders: indoleamine changes and differential clinical effects.
Topics: Affective Symptoms; Blood Platelets; Clinical Trials as Topic; Depression; Humans; Hydroxyindoleacetic Acid; Indoles; Obsessive-Compulsive Disorder; Placebos; Probenecid; Serotonin; Sleep; Tryptophan | 1974 |
Potentiation of a monoamine oxidase inhibitor by tryptophan.
Topics: Clinical Trials as Topic; Depression; Drug Synergism; Female; Humans; Male; Middle Aged; Phenelzine; Placebos; Psychiatric Status Rating Scales; Tryptophan | 1969 |
Investigation into the possible influence of chlorinated amphetamine derivatives on 5-hydroxytryptamine synthesis in man.
Topics: 5-Hydroxytryptophan; Amphetamine; Antidepressive Agents; Brain; Carbon Isotopes; Clinical Trials as Topic; Depression; Humans; Hydroxyindoleacetic Acid; Kidney; Methamphetamine; Serotonin; Tryptophan | 1970 |
Tryptophan and an MAOI (nialamide) in the treatment of depression. A double-blind study.
Topics: Adult; Clinical Trials as Topic; Depression; Female; Humans; Male; Nialamide; Placebos; Psychiatric Status Rating Scales; Sex Factors; Time Factors; Tryptophan | 1971 |
368 other study(ies) available for tryptophan and Depression
| Article | Year |
|---|---|
Targeting hippocampal phospholipid and tryptophan metabolism for antidepressant-like effects of albiflorin.
Topics: Animals; Antidepressive Agents; Bridged-Ring Compounds; Depression; Disease Models, Animal; Hippocampus; Mice; Phospholipids; Stress, Psychological; Tryptophan | 2021 |
Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity.
Topics: Comorbidity; Depression; Feces; Humans; Irritable Bowel Syndrome; Metabolome; Microbiota; Tryptophan | 2022 |
Metabolite trajectories across the perinatal period and mental health: A preliminary study of tryptophan-related metabolites, bile acids and microbial composition.
Topics: Adult; Anxiety; Bile Acids and Salts; Chromatography, Liquid; Depression; Dietary Fiber; Fatty Acids, Volatile; Feasibility Studies; Feces; Female; Gastrointestinal Microbiome; Humans; Kynurenic Acid; Kynurenine; Mental Health; Perinatal Care; Pilot Projects; Pregnancy; Tandem Mass Spectrometry; Tryptophan | 2022 |
Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity.
Topics: Acetylcholinesterase; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Anxiety; Depression; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Memory Disorders; Oxidative Stress; Rats; Reserpine; Stress, Psychological; Tryptophan | 2021 |
Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex.
Topics: Adult; Animals; Depression; Down-Regulation; Eye Proteins; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Phenotype; Prefrontal Cortex; Serpins; Stress, Psychological; Tryptophan | 2022 |
Association between the indole pathway of tryptophan metabolism and subclinical depressive symptoms in obesity: a preliminary study.
Topics: C-Reactive Protein; Depression; Humans; Indoles; Inflammation; Kynurenine; Obesity; Tryptophan | 2022 |
Association of plasma tryptophan concentration with periaqueductal gray matter functional connectivity in migraine patients.
Topics: Anxiety; Case-Control Studies; Depression; Emotions; Female; Humans; Magnetic Resonance Imaging; Male; Migraine Disorders; Pain Perception; Periaqueductal Gray; Synaptic Transmission; Tryptophan | 2022 |
Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancy.
Topics: Cytokines; Depression; Female; Humans; Kynurenine; Neuroinflammatory Diseases; Pregnancy; Tryptophan | 2022 |
Blood versus cerebrospinal fluid: Kynurenine pathway metabolites in depression.
Topics: Depression; Kynurenine; Tryptophan | 2022 |
Brain Functional Network and Amino Acid Metabolism Association in Females with Subclinical Depression.
Topics: Brain; Depression; Electroencephalography; Female; Humans; Phenylalanine; Tryptophan; Tyrosine | 2022 |
Effects of pharmacological treatment on metabolomic alterations in animal models of depression.
Topics: Animals; Depression; Glucose; Inositol; Kynurenine; Lactic Acid; Models, Animal; Serotonin; Tryptophan | 2022 |
The role of oxidative and nitrosative stress and the tryptophan catabolites pathway in the pathogenesis of depression
Topics: Depression; Humans; Nitrosative Stress; Oxidative Stress; Tryptophan | 2022 |
Tryptophan-rich diet ameliorates chronic unpredictable mild stress induced depression- and anxiety-like behavior in mice: The potential involvement of gut-brain axis.
Topics: Animals; Anxiety; Behavior, Animal; Brain-Gut Axis; Depression; Diet; Mice; Serotonin; Stress, Psychological; Tryptophan | 2022 |
Psychological outcomes of COVID-19 survivors at sixth months after diagnose: the role of kynurenine pathway metabolites in depression, anxiety, and stress.
Topics: Anxiety; Biomarkers; COVID-19; Depression; Humans; Kynurenic Acid; Kynurenine; Survivors; Tryptophan | 2022 |
Tryptophan intake is related to a lower prevalence of depressive symptoms during pregnancy in Japan: baseline data from the Kyushu Okinawa Maternal and Child Health Study.
Topics: Calcium; Child; Child Health; Cross-Sectional Studies; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Humans; Isoflavones; Japan; Kynurenic Acid; Kynurenine; Pregnancy; Pregnancy Complications; Prevalence; Quinolinic Acids; Serotonin; Surveys and Questionnaires; Tobacco Smoke Pollution; Tryptophan; Vitamin D | 2022 |
Soy isoflavones alleviate lipopolysaccharide-induced depressive-like behavior by suppressing neuroinflammation, mediating tryptophan metabolism and promoting synaptic plasticity.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Cytokines; Depression; Estrogens; Interleukin-10; Isoflavones; Kynurenine; Lipopolysaccharides; Mice; Neuroinflammatory Diseases; Neuronal Plasticity; NF-kappa B; Serotonin; Sucrose; Synaptophysin; Toll-Like Receptor 4; Tryptophan; Tumor Necrosis Factor-alpha | 2022 |
Berberine ameliorates depression-like behavior in CUMS mice by activating TPH1 and inhibiting IDO1-associated with tryptophan metabolism.
Topics: Animals; Berberine; Chromatography, Liquid; Depression; Disease Models, Animal; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Neurotransmitter Agents; Stress, Psychological; Tandem Mass Spectrometry; Tryptophan; Tryptophan Hydroxylase | 2023 |
Involvement of the gut-brain axis in vascular depression via tryptophan metabolism: A benefit of short chain fatty acids.
Topics: Animals; Brain-Gut Axis; Cytokines; Depression; Fatty Acids, Volatile; Kynurenine; Rats; Serotonin; Sucrose; Tryptophan; Vascular Depression | 2022 |
Dietary Patterns of Treatment-Resistant Depression Patients.
Topics: Depression; Dietary Fats; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Humans; Ketamine; Tryptophan; Vitamins | 2022 |
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Topics: Animals; Antidepressive Agents; Arachidonic Acid; Arginine; Cytokines; Depression; Gastrointestinal Microbiome; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Mice; Mitogen-Activated Protein Kinases; Occludin; Receptors, Aryl Hydrocarbon; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Tryptophan | 2022 |
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
Topics: Animals; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Tryptophan | 2022 |
The Tryptophan Catabolite or Kynurenine Pathway's Role in Major Depression.
Topics: Depression; Depressive Disorder, Major; Humans; Kynurenine; Tryptophan | 2022 |
Involvement of kynurenine pathway between inflammation and glutamate in the underlying etiopathology of CUMS-induced depression mouse model.
Topics: Animals; Depression; Disease Models, Animal; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Mice; Tryptophan | 2022 |
The prevalence and the effect of interferon -γ in the comorbidity of rheumatoid arthritis and depression.
Topics: Animals; Arthritis, Rheumatoid; Comorbidity; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Mice; Prevalence; Tryptophan | 2023 |
Potential shared gene signatures and molecular mechanisms between atherosclerosis and depression: Evidence from transcriptome data.
Topics: Atherosclerosis; Computational Biology; Depression; Gene Expression Profiling; Gene Regulatory Networks; Humans; Lipids; Matrix Metalloproteinase 9; Transcriptome; Tryptophan | 2023 |
Ratio Fluorescent Detecting of Tryptophan and Its Metabolite 5-Hydroxyindole-3-acetic Acid Relevant with Depression via Tb(III) Modified HOFs Hybrids: Further Designing Recyclable Molecular Logic Gate Connected by Back Propagation Neural Network.
Topics: Acetic Acid; Depression; Hydroxyindoleacetic Acid; Reproducibility of Results; Tryptophan | 2023 |
PCSK9 Inhibition Reduces Depressive like Behavior in CUMS-Exposed Rats: Highlights on HMGB1/RAGE/TLR4 Pathway, NLRP3 Inflammasome Complex and IDO-1.
Topics: Animals; Antidepressive Agents; Depression; Dioxygenases; Disease Models, Animal; HMGB1 Protein; Inflammasomes; Kynurenine; NLR Family, Pyrin Domain-Containing 3 Protein; Proprotein Convertase 9; Rats; Rats, Wistar; Stress, Psychological; Toll-Like Receptor 4; Tryptophan | 2023 |
Rifaximin ameliorates depression-like behaviour in chronic unpredictable mild stress rats by regulating intestinal microbiota and hippocampal tryptophan metabolism.
Topics: Animals; Depression; Gastrointestinal Microbiome; Hippocampus; Kynurenine; Rats; Rifaximin; Serotonin; Stress, Psychological; Tryptophan | 2023 |
Tryptophan metabolism as bridge between gut microbiota and brain in chronic social defeat stress-induced depression mice.
Topics: Animals; Bacteria; Brain; Depression; Gastrointestinal Microbiome; Male; Mice; Mice, Inbred C57BL; Social Defeat; Stress, Psychological; Tryptophan | 2023 |
Prophylactic effect of Tongxieyaofang polysaccharide on depressive behavior in adolescent male mice with chronic unpredictable stress through the microbiome-gut-brain axis.
Topics: Animals; Antidepressive Agents; Bile Acids and Salts; Brain-Gut Axis; Depression; Hippocampus; Hypothalamo-Hypophyseal System; Male; Mice; Pituitary-Adrenal System; Polysaccharides; Stress, Psychological; Tryptophan | 2023 |
Genetic risk of depression is different in subgroups of dietary ratio of tryptophan to large neutral amino acids.
Topics: Adult; Amino Acids, Neutral; Depression; Diet; Humans; Kynurenine; Serotonin; Tryptophan | 2023 |
Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor.
Topics: 5-Hydroxytryptophan; Animals; Depression; Female; Kynurenine; Mice; Serotonin; Tryptophan; Whey Proteins | 2023 |
Sex-Dependent Effects of Chronic Restraint Stress on Mood-Related Behaviours and Neurochemistry in Mice.
Topics: Animals; Anxiety; Behavior, Animal; Catecholamines; Depression; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurochemistry; Prefrontal Cortex; Restraint, Physical; Stress, Psychological; Tryptophan | 2023 |
Microbiome and tryptophan metabolomics analysis in adolescent depression: roles of the gut microbiota in the regulation of tryptophan-derived neurotransmitters and behaviors in human and mice.
Topics: Adolescent; Animals; Coleoptera; Depression; Gastrointestinal Microbiome; Humans; Kynurenine; Metabolomics; Mice; Microbiota; Quinolinic Acid; Serotonin; Sertraline; Tryptophan | 2023 |
Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour - studies with chronic nicotine administration in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Dioxygenases; Female; Liver; Male; Mice; Nicotine; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 2023 |
Metabolites for monitoring symptoms and predicting remission in patients with depression who received electroconvulsive therapy: a pilot study.
Topics: Biomarkers; Depression; Depressive Disorder, Major; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Humans; Pilot Projects; Treatment Outcome; Tryptophan | 2023 |
Pre-mating nitenpyram exposure in male mice leads to depression-like behavior in offspring by affecting tryptophan metabolism in gut microbiota.
Topics: Animals; Depression; Gastrointestinal Microbiome; Male; Mice; Pesticides; RNA, Ribosomal, 16S; Tryptophan | 2024 |
A mood state-specific interaction between kynurenine metabolism and inflammation is present in bipolar disorder.
Topics: Adult; Affect; Biomarkers; Bipolar Disorder; C-Reactive Protein; Depression; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Symptom Assessment; Tryptophan | 2020 |
Urinary metabolic disturbance in the olfactory bulbectomized rats and the modulatory effects of fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Depression; Disease Models, Animal; Fluoxetine; Male; Metabolome; Olfactory Bulb; Prefrontal Cortex; Rats, Sprague-Dawley; Tryptophan | 2019 |
γ-[Glu]n-Trp ameliorates anxiety/depression-like behaviors and its anti-inflammatory effect in an animal model of anxiety/depression.
Topics: Animals; Anti-Inflammatory Agents; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Hippocampus; Humans; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Prefrontal Cortex; Tryptophan; Tumor Necrosis Factor-alpha; Whey Proteins | 2019 |
Use of selective serotonin reuptake inhibitors is associated with very low plasma-free serotonin concentrations in humans.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Case-Control Studies; Cross-Sectional Studies; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan; Young Adult | 2020 |
Associations among peripheral and central kynurenine pathway metabolites and inflammation in depression.
Topics: Depression; Humans; Inflammation; Kynurenic Acid; Kynurenine; Tryptophan | 2020 |
The relationship between dietary patterns and depression mediated by serum levels of Folate and vitamin B12.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Depression; Depressive Disorder, Major; Female; Folic Acid; Homocysteine; Humans; Iran; Logistic Models; Male; Middle Aged; Tryptophan; Vitamin B 12; Young Adult | 2020 |
Changes in Gut Microbiota by Chronic Stress Impair the Efficacy of Fluoxetine.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cell Differentiation; Chronic Disease; Depression; Fluoxetine; Gastrointestinal Microbiome; Hippocampus; Male; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Serotonin; Stress, Psychological; Treatment Outcome; Tryptophan | 2020 |
Thymoquinone Loaded Solid Lipid Nanoparticles Demonstrated Antidepressant-Like Activity in Rats via Indoleamine 2, 3- Dioxygenase Pathway.
Topics: Animals; Antidepressive Agents; Behavior Observation Techniques; Behavior, Animal; Benzoquinones; Depression; Disease Models, Animal; Drug Carriers; Hippocampus; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipids; Male; Nanoparticles; Nigella sativa; Rats; Serotonin; Signal Transduction; Tryptophan | 2020 |
Fish-oil supplementation decreases Indoleamine-2,3-Dioxygenase expression and increases hippocampal serotonin levels in the LPS depression model.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Behavior, Animal; Depression; Dietary Supplements; Fatty Acids, Omega-3; Fish Oils; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lipopolysaccharides; Male; Minocycline; Rats; Rats, Wistar; Serotonin; Tryptophan | 2020 |
Effect of repetitive transcranial magnetic stimulation on the kynurenine pathway in stroke patients.
Topics: Aged; Depression; Female; Humans; Kynurenine; Male; Middle Aged; Motor Cortex; Psychiatric Status Rating Scales; Stroke; Transcranial Magnetic Stimulation; Tryptophan | 2020 |
Peripheral and cerebral abnormalities of the tryptophan metabolism in the depression-like rats induced by chronic unpredicted mild stress.
Topics: Animals; Cerebral Cortex; Chronic Disease; Colon; Depression; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Stress, Psychological; Tryptophan | 2020 |
COVID-19, interferons, and depression: A commentary.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Depression; Humans; Interferons; Pandemics; Pneumonia, Viral; SARS-CoV-2; Serotonin; Tryptophan | 2020 |
Depression and tryptophan metabolism in patients with primary brain tumors: Clinical and molecular imaging correlates.
Topics: Brain Neoplasms; Depression; Humans; Magnetic Resonance Imaging; Molecular Imaging; Neoplasm Recurrence, Local; Tryptophan | 2021 |
Involvement of kynurenine pathway in depressive-like behaviour induced by nandrolone decanoate in mice.
Topics: Anabolic Agents; Animals; Behavior, Animal; Corpus Striatum; Depression; Dose-Response Relationship, Drug; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mice; Mice, Inbred C57BL; Nandrolone Decanoate; Prefrontal Cortex; Tryptophan | 2020 |
Tryptophan Intake and Metabolism in Older Adults with Mood Disorders.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Depression; Dietary Supplements; Eating; Female; Humans; Kynurenine; Male; Middle Aged; Mood Disorders; Nutritional Physiological Phenomena; Serotonin; Severity of Illness Index; Signal Transduction; Tryptophan | 2020 |
Identifying a biological signature of prenatal maternal stress.
Topics: Anxiety; Biomarkers; Chemokines; Cohort Studies; Cytokines; Depression; Female; Fetal Development; Humans; Infant, Newborn; Inflammation Mediators; Irritable Bowel Syndrome; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Stress, Psychological; Tryptophan | 2021 |
The Effect of Chronic Mild Stress and Escitalopram on the Expression and Methylation Levels of Genes Involved in the Oxidative and Nitrosative Stresses as Well as Tryptophan Catabolites Pathway in the Blood and Brain Structures.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Catalase; Chronic Disease; Citalopram; Depression; DNA Methylation; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Leukocytes, Mononuclear; Male; Metabolic Networks and Pathways; Nitric Oxide Synthase Type I; Nitrosative Stress; Oxidative Stress; Rats, Wistar; Stress, Psychological; Tryptophan; Tryptophan Hydroxylase | 2020 |
Tryptophan-rich diet is negatively associated with depression and positively linked to social cognition.
Topics: Adolescent; Adult; Aged; Depression; Diet; Eating; Emotions; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Social Cognition; Tryptophan; Young Adult | 2021 |
The role of anthranilic acid in the increase of depressive symptoms and major depressive disorder during treatment for hepatitis C with pegylated interferon-α2a and oral ribavirin.
Topics: Adult; Antiviral Agents; Cross-Sectional Studies; Depression; Depressive Disorder, Major; Female; Hepatitis C, Chronic; Humans; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Longitudinal Studies; Male; Middle Aged; ortho-Aminobenzoates; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Tryptophan | 2021 |
Blockade of Indoleamine 2, 3-dioxygenase 1 ameliorates hippocampal neurogenesis and BOLD-fMRI signals in chronic stress precipitated depression.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Dorsal Raphe Nucleus; Drug Evaluation, Preclinical; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Magnetic Resonance Imaging; Mice, Inbred C57BL; Neurogenesis; Oximes; Stress, Psychological; Sulfonamides; Tryptophan; Tryptophan Hydroxylase | 2021 |
Alterations in the Kynurenine Pathway of Tryptophan Metabolism Are Associated With Depression in People Living With HIV.
Topics: Antidepressive Agents; Comorbidity; Depression; Female; HIV Infections; Humans; Kynurenine; Male; Middle Aged; Psychometrics; Quinolinic Acid; Tryptophan | 2021 |
The effect of tryptophan and serotonin levels on the severity of depressive and climacteric symptoms in perimenopausal women.
Topics: Adult; Aged; Climacteric; Depression; Female; Humans; Middle Aged; Postmenopause; Serotonin; Severity of Illness Index; Tryptophan | 2021 |
The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation.
Topics: Depression; Depressive Disorder, Major; Humans; Inflammation; Kynurenic Acid; Kynurenine; Tryptophan | 2021 |
Prospective study on the association between serum amino acid profiles and depressive symptoms among the Japanese working population.
Topics: Adult; Aged; Arginine; Chromatography, Liquid; Depression; Employment; Female; Glutamic Acid; Health Surveys; Humans; Japan; Logistic Models; Male; Mass Spectrometry; Middle Aged; Odds Ratio; Prospective Studies; Tryptophan | 2021 |
Association between psychological measures with inflammatory anddisease-related markers of inflammatory bowel disease.
Topics: Adult; Aged; Anxiety; Biomarkers; C-Reactive Protein; Case-Control Studies; Colon; Depression; Female; Gene Expression; Humans; Inflammation; Inflammatory Bowel Diseases; Interferon-gamma; Interleukin-1beta; Interleukin-6; Kynurenine; Male; Matrix Metalloproteinase 9; Middle Aged; Quality of Life; Tryptophan | 2017 |
Tryptophan and Kynurenine Levels and Its Association With Sleep, Nonphysical Fatigue, and Depression in Chronic Hemodialysis Patients.
Topics: Adult; Aged; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Depression; Fatigue; Female; Humans; Kynurenine; Male; Middle Aged; Renal Dialysis; Reproducibility of Results; Sleep; Surveys and Questionnaires; Tryptophan | 2017 |
Simvastatin and Bezafibrate ameliorate Emotional disorder Induced by High fat diet in C57BL/6 mice.
Topics: Animals; Behavior, Animal; Bezafibrate; Depression; Diet, High-Fat; Glucose Tolerance Test; Hindlimb Suspension; Hippocampus; Male; Mice; Serotonin; Signal Transduction; Simvastatin; Stress, Psychological; Swimming; Tryptophan | 2017 |
The association between the hypothalamic pituitary adrenal axis and tryptophan metabolism in persons with recurrent major depressive disorder and healthy controls.
Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Depression; Depressive Disorder, Major; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Kynurenine; Male; Middle Aged; Pituitary-Adrenal System; Recurrence; Tandem Mass Spectrometry; Tryptophan | 2017 |
Decreased brain serotonin turnover rate following administration of Sharbat-e-Ahmed Shah produces antidepressant and anxiolytic effect in rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Depression; Medicine, Traditional; Motor Activity; Phytotherapy; Plant Extracts; Rats; Serotonin; Swimming; Tryptophan | 2017 |
Depressive, anxiety and hypomanic symptoms in schizophrenia may be driven by tryptophan catabolite (TRYCAT) patterning of IgA and IgM responses directed to TRYCATs.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Case-Control Studies; Cyclothymic Disorder; Depression; Female; Humans; Immunoglobulin A; Immunoglobulin M; Male; Middle Aged; Schizophrenia; Signal Transduction; Tryptophan; Young Adult | 2018 |
Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder.
Topics: Adult; Affect; Biomarkers; Bipolar Disorder; Depression; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Neopterin; Outcome Assessment, Health Care; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Tryptophan | 2018 |
Activation of indoleamine 2, 3- dioxygenase pathway by olanzapine augments antidepressant effects of venlafaxine in mice.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Depression; Depressive Disorder, Treatment-Resistant; Female; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interleukin-1beta; Interleukin-6; Kynurenine; Male; Mice; Olanzapine; Serotonin; Stress, Psychological; Swimming; Tryptophan; Venlafaxine Hydrochloride | 2017 |
Assessment of tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption.
Topics: Adult; Biomarkers; Breath Tests; Cross-Sectional Studies; Depression; Female; Fructose; Fructose Intolerance; Humans; Kynurenine; Lactase; Lactose Intolerance; Logistic Models; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Tryptophan | 2018 |
Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain.
Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Cytokines; Depression; Hydroxyindoleacetic Acid; Hyperalgesia; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mice, Inbred ICR; Neuralgia; Sciatic Nerve; Serotonin; Stereoisomerism; Tryptophan; Xanthophylls | 2018 |
HMGB1 mediates depressive behavior induced by chronic stress through activating the kynurenine pathway.
Topics: Animals; Depression; Depressive Disorder; Hippocampus; HMGB1 Protein; Hydrolases; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mice; Mice, Inbred BALB C; Motor Activity; Pyruvates; Sirtuin 1; Stress, Psychological; Tryptophan | 2018 |
Regulation of the kynurenine metabolism pathway by Xiaoyao San and the underlying effect in the hippocampus of the depressed rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Kynurenine 3-Monooxygenase; Locomotion; Male; Neural Cell Adhesion Molecules; Quinolinic Acid; Rats, Sprague-Dawley; Signal Transduction; Tryptophan | 2018 |
The role of chronic nutritional supplements consumption in a fulminant serotonin syndrome due to citalopram intoxication.
Topics: Adult; Alcohol Drinking; Antidepressive Agents, Second-Generation; Citalopram; Depression; Dietary Supplements; Fatal Outcome; Humans; Male; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Suicide, Attempted; Suicide, Completed; Taurine; Tryptophan | 2019 |
In Schizophrenia, Depression, Anxiety, and Physiosomatic Symptoms Are Strongly Related to Psychotic Symptoms and Excitation, Impairments in Episodic Memory, and Increased Production of Neurotoxic Tryptophan Catabolites: a Multivariate and Machine Learning
Topics: Adolescent; Adult; Aged; Anxiety; Depression; Female; Humans; Machine Learning; Male; Medically Unexplained Symptoms; Memory Disorders; Middle Aged; Multivariate Analysis; Psychiatric Status Rating Scales; Thailand; Tryptophan; Young Adult | 2018 |
Association between habitual tryptophan intake and depressive symptoms in young and middle-aged women.
Topics: Adult; Age Factors; Cross-Sectional Studies; Depression; Diet; Female; Humans; Japan; Middle Aged; Prevalence; Risk Factors; Surveys and Questionnaires; Tryptophan; Young Adult | 2018 |
Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; China; Chromatography, High Pressure Liquid; Depression; Depressive Disorder, Major; Fatty Acids, Unsaturated; Female; Humans; Inosine; Lipid Metabolism; Male; Mass Spectrometry; Metabolomics; Purines; ROC Curve; Tryptophan | 2019 |
Changes in the tryptophan-kynurenine axis in association to therapeutic response in clinically depressed patients undergoing psychiatric rehabilitation.
Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Combined Modality Therapy; Depression; Female; Humans; Interleukin-6; Kynurenine; Male; Middle Aged; Psychiatric Rehabilitation; Psychiatric Status Rating Scales; Treatment Outcome; Tryptophan | 2018 |
Psychosocial stress and inflammation driving tryptophan breakdown in children and adolescents: A cross-sectional analysis of two cohorts.
Topics: Adolescent; C-Reactive Protein; Child; Cohort Studies; Cross-Sectional Studies; Cytokines; Depression; Depressive Disorder; Female; Humans; Inflammation; Interferon-gamma; Interleukin-6; Kynurenic Acid; Kynurenine; Male; Stress, Psychological; Tryptophan; Tumor Necrosis Factor-alpha | 2018 |
Simultaneous determination of tryptophan, kynurenine, kynurenic acid and two monoamines in rat plasma by HPLC-ECD/DAD.
Topics: Amino Acids, Essential; Animals; Boron; Chemical Fractionation; Chromatography, High Pressure Liquid; Depression; Diamond; Electrochemical Techniques; Electrodes; Fluorescence; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Limit of Detection; Models, Animal; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Tryptophan | 2018 |
Gentiopicroside abrogates lipopolysaccharide-induced depressive-like behavior in mice through tryptophan-degrading pathway.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Hindlimb Suspension; Inflammation Mediators; Iridoid Glucosides; Lipopolysaccharides; Male; Mice; Motor Activity; Signal Transduction; Swimming; Tryptophan | 2018 |
Alterations in the metabolism of tryptophan in patients with chronic hepatitis C six months after pegylated interferon-α 2a treatment.
Topics: Adult; Antiviral Agents; Depression; Depressive Disorder; Female; Hepatitis C; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Polyethylene Glycols; Recombinant Proteins; Tryptophan | 2018 |
Disruption of microglia histone acetylation and protein pathways in mice exhibiting inflammation-associated depression-like symptoms.
Topics: Acetylation; Animals; Depression; Disease Models, Animal; Histones; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Male; Mice; Mice, Inbred C57BL; Microglia; Protein Processing, Post-Translational; Serotonin; Tryptophan | 2018 |
Naringenin protects against oxido-inflammatory aberrations and altered tryptophan metabolism in olfactory bulbectomized-mice model of depression.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain Chemistry; Cytokines; Depression; Estrogen Antagonists; Flavanones; Fluoxetine; Inflammation; Kynurenine; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Motor Activity; Olfactory Bulb; Oxidative Stress; Tryptophan | 2018 |
A step ahead: Exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode.
Topics: Biomarkers; Bipolar Disorder; Case-Control Studies; Cross-Sectional Studies; Depression; Depressive Disorder; Gastrointestinal Microbiome; Humans; Inflammation; Inpatients; Kynurenine; Male; Tryptophan | 2019 |
Antidepressant effects of direct-acting antivirals against hepatitis C virus-Results from a pilot study.
Topics: Actigraphy; Adult; Aged; Antiviral Agents; Depression; Exercise; Fatigue; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver; Male; Middle Aged; Pilot Projects; Ribavirin; Treatment Outcome; Tryptophan; Viral Load; Young Adult | 2018 |
Antidepressant effect of repeated ketamine administration on kynurenine pathway metabolites in patients with unipolar and bipolar depression.
Topics: Administration, Intravenous; Adult; Antidepressive Agents; Bipolar Disorder; China; Chromatography, Liquid; Depression; Depressive Disorder; Female; Humans; Ketamine; Kynurenic Acid; Kynurenine; Male; Tandem Mass Spectrometry; Tryptophan | 2018 |
Cross-sectional relationship between kynurenine pathway metabolites and cognitive function in major depressive disorder.
Topics: Adult; Chromatography, Liquid; Cognition; Cross-Sectional Studies; Depression; Depressive Disorder, Major; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Quinolinic Acid; Tryptophan | 2019 |
Supervised machine learning to decipher the complex associations between neuro-immune biomarkers and quality of life in schizophrenia.
Topics: Adolescent; Adult; Aged; Anxiety; Biomarkers; Case-Control Studies; Depression; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Schizophrenia; Schizophrenic Psychology; Supervised Machine Learning; Tryptophan; Young Adult | 2019 |
Supplementation with Lactobacillus kefiranofaciens ZW3 from Tibetan Kefir improves depression-like behavior in stressed mice by modulating the gut microbiota.
Topics: Animals; Bacteria; Behavior, Animal; Cytokines; Depression; Feces; Gastrointestinal Microbiome; Kefir; Lactobacillus; Male; Mice; Probiotics; Spleen; Stress, Physiological; Sucrose; Swimming; Tibet; Tryptophan | 2019 |
A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients.
Topics: Aged; Amino Acids; Brain; Depression; Female; Humans; Male; Microdialysis; Middle Aged; Phenylalanine; Subarachnoid Hemorrhage; Tryptophan; Tyrosine | 2019 |
Development and validation of the 22-item Tarumi's Modern-Type Depression Trait Scale: Avoidance of Social Roles, Complaint, and Low Self-Esteem (TACS-22).
Topics: Adolescent; Adult; Depression; Female; Humans; Male; Middle Aged; Prodromal Symptoms; Psychiatric Status Rating Scales; Psychometrics; Self Concept; Self Report; Sensitivity and Specificity; Social Behavior; Tryptophan; Young Adult | 2019 |
How acute and chronic physical disease may influence mental health - An Analysis of neurotransmitter precursor amino acid levels.
Topics: Acute Disease; Adult; Aged; Amino Acids; Anxiety Disorders; C-Reactive Protein; Chronic Disease; Depression; Depressive Disorder; Female; Humans; Inflammation; Kynurenine; Male; Mental Disorders; Mental Health; Middle Aged; Neurotransmitter Agents; Phenylalanine; Prospective Studies; Tryptophan; Tyrosine | 2019 |
The association between plasma cholesterol and the effect of tryptophan depletion on heart rate variability.
Topics: Adult; Anxiety; Autonomic Nervous System; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Depression; Female; Heart Rate; Humans; Male; Middle Aged; Serotonin; Tryptophan | 2019 |
Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.
Topics: Animals; Antidepressive Agents; Autonomic Nervous System; Biphenyl Compounds; Brain; Calcium; Cytokines; Depression; Disease Models, Animal; Hindlimb Suspension; Immobilization; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Lignans; Lipopolysaccharides; Mice, Inbred ICR; NF-kappa B; RNA, Messenger; Swimming; Tryptophan | 2019 |
Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms.
Topics: Adult; Depression; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Postpartum Period; Pregnancy; Psychiatric Status Rating Scales; Tryptophan | 2019 |
Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats.
Topics: Animals; Blood Chemical Analysis; Chromatography, Liquid; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Kynurenic Acid; Kynurenine; Limit of Detection; Linear Models; Male; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Tryptophan; Urinalysis | 2019 |
Editorial.
Topics: Animals; Antisocial Personality Disorder; Biological Psychiatry; Biomarkers; Bipolar Disorder; Cognition; Depression; Disease Models, Animal; Histocompatibility Antigens Class II; Humans; Mice; Tryptophan | 2019 |
Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin.
Topics: Aging; Anhedonia; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depression; Hindlimb Suspension; Illness Behavior; Inflammation; Kynurenine; Lung; Mice; Mice, Inbred BALB C; Motor Activity; Mycobacterium bovis; Mycobacterium Infections; Spleen; Tryptophan | 2013 |
Depressive symptoms in Crohn's disease: relationship with immune activation and tryptophan availability.
Topics: Adult; Affect; Crohn Disease; Depression; Fatigue; Female; Humans; Immunity; Male; Quality of Life; Reference Values; Surveys and Questionnaires; Time Factors; Tryptophan; Tumor Necrosis Factor-alpha | 2013 |
Regular moderate or intense exercise prevents depression-like behavior without change of hippocampal tryptophan content in chronically tryptophan-deficient and stressed mice.
Topics: Animals; Avoidance Learning; Brain Chemistry; Cell Proliferation; Depression; Hippocampus; Male; Memory, Long-Term; Memory, Short-Term; Mice; Mice, Inbred C57BL; Norepinephrine; Physical Conditioning, Animal; Rats; Serotonin; Stress, Psychological; Tryptophan | 2013 |
Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; Exploratory Behavior; Food Preferences; Indoleamine-Pyrrole 2,3,-Dioxygenase; Injections, Intraventricular; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Sucrose; Time Factors; Tryptophan; Up-Regulation | 2013 |
C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy.
Topics: Biomarkers; Breast Neoplasms; C-Reactive Protein; Cytokines; Depression; Fatigue; Female; Humans; Inflammation; Kynurenine; Middle Aged; Tryptophan | 2013 |
In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Chickens; Depression; Disease Models, Animal; Humans; Monoamine Oxidase; Protein Binding; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Structure-Activity Relationship; Tryptophan | 2013 |
Symptoms of depression and anxiety in anorexia nervosa: links with plasma tryptophan and serotonin metabolism.
Topics: Adolescent; Adult; Anorexia Nervosa; Anxiety; Depression; Female; Humans; Male; Nutritional Status; Serotonin; Surveys and Questionnaires; Tryptophan | 2014 |
Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.
Topics: Adult; Case-Control Studies; Depression; Exercise; Female; Humans; Hydroxyindoleacetic Acid; Interleukin-6; Kynurenine; Male; Middle Aged; Neopterin; Severity of Illness Index; Somatoform Disorders; Tryptophan | 2013 |
Reversal of the Kynurenine pathway of tryptophan catabolism may improve depression in ART-treated HIV-infected Ugandans.
Topics: Adult; Antiretroviral Therapy, Highly Active; Depression; Female; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Metabolic Networks and Pathways; Plasma; Treatment Outcome; Tryptophan; Uganda | 2014 |
Gonadal hormone levels and platelet tryptophan and serotonin concentrations in perimenopausal women with or without depressive symptoms.
Topics: Anxiety; Blood Platelets; Depression; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Female; Gonadal Hormones; Hot Flashes; Humans; Mexico; Middle Aged; Perimenopause; Psychiatric Status Rating Scales; Self Report; Serotonin; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Tryptophan | 2014 |
A biological basis for depression in pancreatic cancer.
Topics: Adenocarcinoma; Affect; Aged; Aged, 80 and over; Depression; Female; Humans; Kynurenine; Lymphatic Metastasis; Male; Middle Aged; Pancreatic Neoplasms; Risk Factors; Signal Transduction; Surveys and Questionnaires; Tryptophan; Tumor Burden | 2014 |
Lipopolysaccharide-induced brain activation of the indoleamine 2,3-dioxygenase and depressive-like behavior are impaired in a mouse model of metabolic syndrome.
Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Enzyme Activation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipopolysaccharides; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic; Receptors, Leptin; Tryptophan | 2014 |
Activation of brain indoleamine 2,3-dioxygenase contributes to epilepsy-associated depressive-like behavior in rats with chronic temporal lobe epilepsy.
Topics: Animals; Chromatography, Liquid; Cytokines; Depression; Disease Models, Animal; Epilepsy, Temporal Lobe; Food Preferences; Gene Expression Regulation; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lithium Chloride; Male; Mass Spectrometry; Minocycline; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors; Tryptophan | 2014 |
Activation of the kynurenine pathway in the acute phase of stroke and its role in fatigue and depression following stroke.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Case-Control Studies; Depression; Fatigue; Female; Humans; Kynurenine; Male; Middle Aged; Prognosis; Serotonin; Stroke; Tryptophan | 2014 |
Does tryptophan degradation along the kynurenine pathway mediate the association between pro-inflammatory immune activity and depressive symptoms?
Topics: Adolescent; Adult; Aged; Case-Control Studies; Depression; Depressive Disorder, Major; Female; Humans; Immune System; Inflammation; Inflammation Mediators; Kynurenine; Male; Metabolic Networks and Pathways; Middle Aged; Netherlands; Proteolysis; Tryptophan; Young Adult | 2014 |
Orally administered whole egg demonstrates antidepressant-like effects in the forced swimming test on rats.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Eggs; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Inbred WKY; Rats, Wistar; Serotonin; Stress, Psychological; Swimming; Tryptophan | 2014 |
Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Gene Expression; Hippocampus; Imipramine; Kynurenine; Lipopolysaccharides; Male; Pentoxifylline; Rats; Stress, Psychological; Tryptophan; Tumor Necrosis Factor-alpha | 2014 |
The relationship of alcohol use disorders and depressive symptoms to tryptophan metabolism: cross-sectional data from a Nepalese alcohol treatment sample.
Topics: Adult; Alcohol-Related Disorders; Biomarkers; Cross-Sectional Studies; Depression; Female; Humans; Kynurenine; Male; Middle Aged; Nepal; Treatment Outcome; Tryptophan; Young Adult | 2015 |
Interferon-alpha treatment induces depression-like behaviour accompanied by elevated hippocampal quinolinic acid levels in rats.
Topics: Animals; Antidepressive Agents; Chromatography, Liquid; Depression; Dose-Response Relationship, Drug; Electrochemistry; Food Preferences; Hippocampus; Illness Behavior; Interferon-alpha; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Saccharin; Statistics, Nonparametric; Sweetening Agents; Swimming; Tryptophan | 2015 |
Dietary protein ingested before and during short photoperiods makes an impact on affect-related behaviours and plasma composition of amino acids in mice.
Topics: Amino Acids; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Caseins; Depression; Dietary Proteins; Fatty Acids, Nonesterified; Glutens; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Photoperiod; Seasonal Affective Disorder; Serotonin; Soybean Proteins; Swimming; Tryptophan | 2015 |
Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Cytokines; Depression; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluoxetine; Hippocampus; Ibuprofen; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Male; Minocycline; Molecular Targeted Therapy; Motor Activity; Norepinephrine; Rats, Wistar; Serotonin; Swimming; Tryptophan; Weight Gain | 2016 |
Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis.
Topics: Depression; Depressive Disorder, Major; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Male; Mast Cells; Mastocytosis; Middle Aged; Psychiatric Status Rating Scales; Serotonin; Stress, Psychological; Tryptophan | 2016 |
Tryptophan-induced pathogenesis of breast cancer.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Breast Neoplasms; Case-Control Studies; CD4-Positive T-Lymphocytes; Depression; Female; Humans; Interleukin-10; Middle Aged; RNA, Messenger; Tryptophan | 2015 |
Indoleamine-2,3-dioxygenase mediates neurobehavioral alterations induced by an intracerebroventricular injection of amyloid-β1-42 peptide in mice.
Topics: Amyloid beta-Peptides; Animals; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Injections, Intraventricular; Kynurenine; Memory Disorders; Mice; Nerve Growth Factors; Peptide Fragments; Prefrontal Cortex; Recognition, Psychology; Tryptophan | 2016 |
The role of tryptophan degradation in the association between inflammatory markers and depressive symptoms in chronic dialysis patients.
Topics: Adult; Aged; Biomarkers; C-Reactive Protein; Depression; Female; Glomerulonephritis; Humans; Incidence; Interleukin-10; Interleukin-1beta; Interleukin-6; Kynurenine; Male; Middle Aged; Prospective Studies; Renal Dialysis; Tryptophan; Tumor Necrosis Factor-alpha | 2017 |
Adipogenesis and aldosterone: a study in lean tryptophan-depleted rats.
Topics: Adipogenesis; Aldosterone; Animals; Corticosterone; Depression; Female; Rats; Rats, Sprague-Dawley; Tryptophan | 2016 |
Body image dissatisfaction in pregnant and non-pregnant females is strongly predicted by immune activation and mucosa-derived activation of the tryptophan catabolite (TRYCAT) pathway.
Topics: Adult; Body Image; Depression; Female; Humans; Immunoglobulin A; Immunoglobulin M; Inflammation; Metabolic Networks and Pathways; Mucous Membrane; Personal Satisfaction; Postpartum Period; Pregnancy; Pregnancy Complications; Prospective Studies; Tryptophan | 2018 |
Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1.
Topics: Animals; Behavior, Animal; Depression; Enzyme Induction; Female; Frontal Lobe; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Interferon-gamma; Kynurenine; Male; Metabolome; Mice, Inbred C57BL; Middle Aged; Serotonin; Swimming; Tryptophan | 2016 |
Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Freund's Adjuvant; Hippocampus; Hyperalgesia; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interleukin-1beta; Interleukin-6; Ketamine; Kynurenine; Male; Nociception; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2016 |
Comparison of fluoxetine and 1-methyl-L-tryptophan in treatment of depression-like illness in Bacillus Calmette-Guerin-induced inflammatory model of depression in mice.
Topics: Animals; Antidepressive Agents; BCG Vaccine; Depression; Disease Models, Animal; Fluoxetine; Inflammation; Male; Mice; Mice, Inbred C57BL; Random Allocation; Treatment Outcome; Tryptophan | 2016 |
A Simple HPLC-MS/MS Method for Determination of Tryptophan, Kynurenine and Kynurenic Acid in Human Serum and its Potential for Monitoring Antidepressant Therapy.
Topics: Antidepressive Agents; Case-Control Studies; Chromatography, High Pressure Liquid; Depression; Drug Monitoring; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tryptophan | 2017 |
Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cytokines; Depression; Fluoxetine; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Male; Mice, Inbred BALB C; Signal Transduction; Stress, Psychological; Time Factors; Tryptophan | 2016 |
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female; Glomerular Filtration Rate; Humans; Hydrocortisone; Indican; Indoleacetic Acids; Inflammation; Kynurenic Acid; Male; Middle Aged; Neopterin; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Surveys and Questionnaires; Tasmania; Tryptophan | 2016 |
Intracerebroventricular Administration of Streptozotocin as an Experimental Approach to Depression: Evidence for the Involvement of Proinflammatory Cytokines and Indoleamine-2,3-Dioxygenase.
Topics: Animals; Blood Glucose; Cytokines; Depression; Disease Models, Animal; Grooming; Hippocampus; Hydroxyindoleacetic Acid; Immobility Response, Tonic; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infusions, Intraventricular; Kynurenine; Male; Mice; Minocycline; Serotonin; Streptozocin; Tryptophan | 2017 |
Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder.
Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Cognition; Depression; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Multivariate Analysis; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan | 2017 |
Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain; Corticosterone; Depression; Disease Models, Animal; Gastrointestinal Microbiome; Gastrointestinal Tract; Gene Expression; Locomotion; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Nociception; Oligosaccharides; Prebiotics; Stress, Psychological; Tryptophan | 2017 |
Physio-somatic symptoms in schizophrenia: association with depression, anxiety, neurocognitive deficits and the tryptophan catabolite pathway.
Topics: Adolescent; Adult; Aged; Anxiety; Cognition Disorders; Depression; Female; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Symptom Assessment; Tryptophan; Young Adult | 2017 |
Strain differences in paroxetine-induced reduction of immobility time in the forced swimming test in mice: role of serotonin.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain Chemistry; Depression; Male; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Swimming; Tryptophan | 2008 |
Influence of chronic mild stress on the behavioural effects of acute tryptophan depletion induced by a gelatin-based mixture.
Topics: Amino Acids; Animals; Anxiety; Appetitive Behavior; Arousal; Behavior, Animal; Body Weight; Depression; Fear; Male; Maze Learning; Mental Recall; Motivation; Pattern Recognition, Visual; Rats; Serotonin; Social Behavior; Stress, Psychological; Taste; Tryptophan | 2008 |
The effects of acute tryptophan depletion on affective behaviour and cognition in Brown Norway and Sprague Dawley rats.
Topics: Affect; Animals; Anxiety; Behavior, Animal; Cognition; Depression; Dietary Carbohydrates; Dietary Proteins; Frontal Lobe; Hippocampus; Hydroxyindoleacetic Acid; Interpersonal Relations; Male; Motor Activity; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Reaction Time; Recognition, Psychology; Serotonin; Species Specificity; Swimming; Tryptophan | 2010 |
AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats.
Topics: Animals; Autoradiography; Brain Chemistry; Depression; Enzyme Activation; Linear Models; Piperidones; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2009 |
Indoleamine 2,3-dioxygenase activation and depressive symptoms in patients with coronary artery disease.
Topics: Coronary Artery Disease; Depression; Enzyme Activation; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Physical Fitness; Tryptophan | 2009 |
The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Aspartic Acid; Brain; Brain Mapping; Choline; Depression; Female; Humans; Kynurenine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Psychiatric Status Rating Scales; Statistics, Nonparametric; Tryptophan; Young Adult | 2010 |
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression.
Topics: Adult; Antiviral Agents; Chemokine CCL2; Chromatography, High Pressure Liquid; Cytokines; Depression; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis C; Humans; Interferon-alpha; Kynurenine; Longitudinal Studies; Male; Middle Aged; Quinolinic Acid; Receptors, Tumor Necrosis Factor, Type II; Ribavirin; Statistics as Topic; Tryptophan | 2010 |
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.
Topics: Animals; Antidepressive Agents; Arginine Vasopressin; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Citalopram; Concanavalin A; Corticosterone; Corticotropin-Releasing Hormone; Cytokines; Depression; Disease Models, Animal; Female; Lipopolysaccharides; Maternal Deprivation; Probiotics; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Tryptophan | 2010 |
Effects of PEG-interferon alpha plus ribavirin on tryptophan metabolism in patients with chronic hepatitis C.
Topics: Adult; Antiviral Agents; Case-Control Studies; Depression; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon alpha-2; Interferon-alpha; Italy; Kynurenine; Male; Middle Aged; Polyethylene Glycols; Psychiatric Status Rating Scales; Recombinant Proteins; Ribavirin; Serotonin; Time Factors; Treatment Outcome; Tryptophan | 2011 |
Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide.
Topics: Animals; Behavior, Animal; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Depression; Humans; Immunity, Innate; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Motor Activity; Oxygenases; Receptors, Chemokine; Social Behavior; Tryptophan | 2010 |
Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: focus on individual differences.
Topics: Amygdala; Animals; Anxiety; Brain; Depression; Gyrus Cinguli; Kynurenine; Male; Maze Learning; Mice; Mice, Inbred BALB C; Models, Animal; Serotonin; Signal Transduction; Stress, Physiological; Swimming; Tryptophan | 2011 |
Moderating effect of indoleamine 2,3-dioxygenase (IDO) activation in the association between depressive symptoms and carotid atherosclerosis: evidence from the Young Finns study.
Topics: Adult; Atherosclerosis; Carotid Artery Diseases; Depression; Dioxygenases; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Kynurenine; Longitudinal Studies; Male; Psychiatric Status Rating Scales; Risk Factors; Sex Factors; Tryptophan; Tryptophan-tRNA Ligase; Women; Young Adult | 2011 |
Effects of chronic administration of tryptophan with or without concomitant fluoxetine in depression-related and anxiety-like behaviors on adult rat.
Topics: Age Factors; Animals; Anxiety; Depression; Drug Therapy, Combination; Fluoxetine; Male; Rats; Rats, Wistar; Tryptophan | 2011 |
Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy.
Topics: Animals; Anorexia; Anti-Inflammatory Agents; Antidepressive Agents; Behavior, Animal; Blood-Brain Barrier; Brain; Cell Line; Cytokines; Depression; Encephalitis; Ginsenosides; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipopolysaccharides; Male; Mice; Neuropsychological Tests; Panax; Serotonin; Tissue Distribution; Tryptophan; Weight Loss | 2011 |
[Simultaneous determination of tryptophan and its key metabolites by high performance liquid chromatography with programmed wavelength ultraviolet detection].
Topics: Adolescent; Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Depression; Female; Humans; Kynurenine; Male; Serotonin; Spectrophotometry, Ultraviolet; Tryptophan; Young Adult | 2011 |
Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity.
Topics: Aldosterone; Analysis of Variance; Animals; Body Weight; Brain; Calcium-Binding Proteins; Catecholamines; Chromatography, High Pressure Liquid; Corticosterone; Depression; Diet; Disease Models, Animal; DNA-Binding Proteins; Kynurenic Acid; Kynurenine; Male; Nerve Tissue Proteins; Nucleobindins; Paroxetine; Protein Binding; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Swimming; Time Factors; Tritium; Tryptophan | 2012 |
The role of indoleamine 2,3-dioxygenase in a mouse model of neuroinflammation-induced depression.
Topics: Animals; Depression; Disease Models, Animal; Encephalitis; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Maze Learning; Mice; Mice, Inbred C57BL; Tryptophan | 2012 |
Affective regulation of cognitive-control adjustments in remitted depressive patients after acute tryptophan depletion.
Topics: Adaptation, Psychological; Adolescent; Adult; Aged; Analysis of Variance; Cognition Disorders; Conflict, Psychological; Depression; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Reaction Time; Serotonin; Social Adjustment; Tryptophan; Young Adult | 2012 |
The integrated model of serotonin transporter gene variation (5HTTLPR) and the glial cell transporter in stress vulnerability and depression.
Topics: Depression; Genetic Variation; Humans; Models, Biological; Neuroglia; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Synaptic Transmission; Tryptophan | 2012 |
Diagnostic classifications in depression and somatization should include biomarkers, such as disorders in the tryptophan catabolite (TRYCAT) pathway.
Topics: Adult; Analysis of Variance; Biomarkers; Chi-Square Distribution; Depression; Female; Humans; International Classification of Diseases; Kynurenic Acid; Kynurenine; Male; Middle Aged; Principal Component Analysis; Psychiatric Status Rating Scales; Somatoform Disorders; Tryptophan | 2012 |
Alterations on the morphology, nitric oxide synthesis and activity of platelets reproduced in rats as possible biomarkers for depression are reversed by fluoxetine.
Topics: Animals; Behavior, Animal; Biomarkers; Blood Platelets; Depression; Fluoxetine; Male; Membrane Potentials; Nitric Oxide; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan | 2012 |
Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma.
Topics: 3-Hydroxyanthranilic Acid; Animals; Charcoal; Chromatography, High Pressure Liquid; Depression; Kynurenic Acid; Kynurenine; Linear Models; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Schizophrenia; Social Isolation; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan | 2012 |
Modulatory effects of acupuncture on murine depression-like behavior following chronic systemic inflammation.
Topics: Acupuncture Therapy; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Chronic Disease; Depression; Dopamine; Inflammation; Kynurenine; Male; Mice; Mice, Inbred BALB C; Motor Activity; Tryptophan | 2012 |
Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice.
Topics: Animals; Behavior, Animal; Brain; CX3C Chemokine Receptor 1; Depression; Hydroxyindoleacetic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipopolysaccharides; Mice; Microglia; Motor Activity; Receptors, Cytokine; Receptors, HIV; Serotonin; Tryptophan | 2013 |
Disturbance of serotonergic neurotransmission in patients with postmyocardial infarction and depression.
Topics: Aged; Cross-Sectional Studies; Depression; Female; Humans; Male; Middle Aged; Myocardial Infarction; Serotonin; Synaptic Transmission; Tryptophan | 2013 |
Regional brain serotonin synthesis is increased in the olfactory bulbectomy rat model of depression: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Depression; Disease Models, Animal; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2003 |
Acute tryptophan depletion induces depressive symptoms in subgroups of recovered depressed patients.
Topics: Depression; Humans; Recovery of Function; Seasonal Affective Disorder; Tryptophan | 2003 |
[Urinary excretion of 5-hydroxyindolacetic acid (5-HIAA) in 150 patients with depressive syndrome and maniacal agitation. (Its modifications by 5-hydroxy-tryptophan loading and therapy in the depressive states)].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Monoamine Oxidase Inhibitors; Tryptophan | 1963 |
POTENTIATION OF MONOAMINE-OXIDASE INHIBITORS BY TRYPTOPHAN.
Topics: Depression; Depressive Disorder; Humans; Monoamine Oxidase Inhibitors; Oxidoreductases; Pharmacology; Tryptophan | 1963 |
Re: Personality and the risk of cancer.
Topics: Depression; Humans; Interferon-gamma; Neoplasms; Personality; Prospective Studies; Risk Assessment; Risk Factors; Serotonin; Tryptophan | 2003 |
Psychobiological aspects of somatoform disorders: contributions of monoaminergic transmitter systems.
Topics: Adult; Amino Acids, Branched-Chain; Analysis of Variance; Biogenic Monoamines; Case-Control Studies; Depression; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Interview, Psychological; Male; Middle Aged; Models, Biological; Phenylalanine; Somatoform Disorders; Tryptophan | 2004 |
Inflamed brains can trigger the blues, studies suggest.
Topics: Cytokines; Depression; Encephalitis; Humans; Neurotransmitter Agents; Tryptophan | 2004 |
Malabsorption of carbohydrates and depression in children and adolescents.
Topics: Adolescent; Biological Availability; Child; Depression; Dietary Carbohydrates; Female; Fructose; Humans; Intestinal Absorption; Lactose; Lactose Intolerance; Malabsorption Syndromes; Male; Serotonin; Spain; Tryptophan | 2005 |
Do high leucine/low tryptophan dieting foods (yogurt, gelatin) with niacin supplementation cause neuropsychiatric symptoms (depression) but not dermatological symptoms of pellagra?
Topics: Depression; Dietary Supplements; Gelatin; Humans; Leucine; Niacin; Pellagra; Tryptophan; Yogurt | 2005 |
National Institutes of Health State of the Science Conference statement on Manifestations and Management of Chronic Insomnia in Adults, June 13-15, 2005.
Topics: Adult; Antidepressive Agents; Benzodiazepines; Chronic Disease; Cognition Disorders; Cognitive Behavioral Therapy; Comorbidity; Cost of Illness; Depression; Humans; Incidence; Prevalence; Sleep Initiation and Maintenance Disorders; Tryptophan | 2005 |
Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.
Topics: Animals; Antidepressive Agents; Biopterins; Brain; Chlorocebus aethiops; COS Cells; Depression; Enzyme Induction; Freezing Reaction, Cataleptic; Gene Expression Regulation, Developmental; Humans; Imipramine; Mice; Mice, Inbred Strains; Paroxetine; Raphe Nuclei; Recombinant Fusion Proteins; RNA, Messenger; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2006 |
Rats subjected to extended L-tryptophan restriction during early postnatal stage exhibit anxious-depressive features and structural changes.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain; Bromodeoxyuridine; Cell Count; Depression; Diet, Protein-Restricted; Disease Models, Animal; Immunohistochemistry; Male; Maze Learning; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin; Silver Staining; Swimming; Tryptophan; Tryptophan Hydroxylase | 2006 |
Low serum tryptophan levels, reduced macrophage IDO activity and high frequency of psychopathology in HCV patients.
Topics: Adult; Anxiety; Depression; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Macrophages; Male; Middle Aged; Tryptophan | 2006 |
Effects of acute tryptophan depletion on mood and facial emotion perception related brain activation and performance in healthy women with and without a family history of depression.
Topics: Adult; Affect; Brain; Brain Chemistry; Brain Mapping; Depression; Emotions; Facial Expression; Family Health; Female; Humans; Magnetic Resonance Imaging; Neuropsychological Tests; Reaction Time; Tryptophan | 2007 |
Low-dose tryptophan depletion.
Topics: Brain Chemistry; Cognition; Depression; Diet, Protein-Restricted; Humans; Tryptophan | 2007 |
Cognitive and serotonergic vulnerability to depression: convergent findings.
Topics: Adult; Cognition Disorders; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Male; Personality Disorders; Serotonin; Tryptophan | 2007 |
Deep brain stimulation of the lateral habenula in treatment resistant major depression.
Topics: Animals; Antidepressive Agents; Deep Brain Stimulation; Depression; Depressive Disorder, Major; Electric Stimulation; Electrophysiology; Habenula; Humans; Models, Theoretical; Positron-Emission Tomography; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine | 2007 |
Influence of sex and estrous cycle on the effects of acute tryptophan depletion induced by a gelatin-based mixture in adult Wistar rats.
Topics: Amino Acids; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Depression; Estrous Cycle; Female; Gelatin; Interpersonal Relations; Male; Motor Activity; Rats; Rats, Wistar; Reaction Time; Recognition, Psychology; Serotonin; Sex Characteristics; Swimming; Tryptophan | 2007 |
Serotonergic mediation effects of St John's wort in rats subjected to swim stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Disease Models, Animal; Hydroxyindoleacetic Acid; Hypericum; Injections, Intraperitoneal; Male; Motor Activity; Plant Extracts; Rats; Rats, Wistar; Serotonin; Stress, Psychological; Swimming; Tryptophan; Tryptophan Oxygenase | 2008 |
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice.
Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cytokinins; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Hindlimb Suspension; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Minocycline; Motor Activity; Swimming; Time Factors; Tryptophan | 2009 |
Quality of life and immune activation in patients with HIV-infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Depression; Disease Progression; Female; Health Status Indicators; Hemoglobins; HIV Infections; Humans; Immunity; Kynurenine; Male; Middle Aged; Neopterin; Predictive Value of Tests; Psychological Tests; Quality of Life; Regression Analysis; Surveys and Questionnaires; Tryptophan; Viral Load | 2008 |
The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium; Biogenic Monoamines; Brain; Chromatography, High Pressure Liquid; Corticosterone; Corticotropin-Releasing Hormone; Cytokines; Depression; Disease Models, Animal; Flow Cytometry; Hypothalamus; Immunoenzyme Techniques; Intestines; Kynurenic Acid; Male; Polymerase Chain Reaction; Probiotics; Rats; Rats, Sprague-Dawley; Stress, Psychological; Tryptophan; Vasopressins | 2008 |
Resistance to inhibiting effect of dexamethasone in patients with endogenous depression.
Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anti-Anxiety Agents; Corticotropin-Releasing Hormone; Depression; Dexamethasone; Diazepam; Drug Synergism; Female; Humans; Levodopa; Male; Middle Aged; Serotonin; Tryptophan | 1980 |
Injectable and oral contraceptive steroids in relation to some neurotransmitters in the rat brain.
Topics: Acetylcholine; Animals; Brain; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Depression; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Neurotransmitter Agents; Rats; Serotonin; Tryptophan | 1981 |
Substances related to 5-hydroxytryptamine in plasma and in lumbar and ventricular fluids of psychiatric patients.
Topics: Adult; Affective Symptoms; Cerebral Ventricles; Depression; Fatty Acids, Nonesterified; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Serotonin; Tryptophan; Tyrosine | 1980 |
[Current biochemical conceptions of mental diseases. II. Role of changes in the biogenic amine system in the pathogenesis of affective disorders].
Topics: 3-Methoxy-4-hydroxyphenylethanol; Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain; Catechol O-Methyltransferase; Cyclic AMP; Depression; Dopamine; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenine; Monoamine Oxidase Inhibitors; Norepinephrine; Receptors, Dopamine; Reserpine; Serotonin; Tryptophan | 1980 |
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; Dihydroxyphenylalanine; Electrochemistry; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Subarachnoid Hemorrhage; Tryptophan; Tyrosine | 1984 |
CSF AMP in primary affective disorder: effects of probenecid and tryptophan.
Topics: Bipolar Disorder; Cyclic AMP; Depression; Humans; Probenecid; Tryptophan | 1980 |
[Free and total tryptophan in the plasma of healthy persons and in patients with depressive disease. Results of a study in 14 patients].
Topics: Adult; Aged; Depression; Female; Humans; Male; Middle Aged; Tryptophan | 1983 |
Relevance of tryptophan and tyrosine availability in endogenous and 'non-endogenous' depressives treated with imipramine or clomipramine.
Topics: Biological Availability; Clomipramine; Depression; Depressive Disorder; Humans; Imipramine; Time Factors; Tryptophan; Tyrosine | 1981 |
Tryptophan in the treatment of depression.
Topics: Allopurinol; Antidepressive Agents, Tricyclic; Ascorbic Acid; Bipolar Disorder; Depression; Electroconvulsive Therapy; Humans; Monoamine Oxidase Inhibitors; Niacinamide; Pyridoxine; Tryptophan | 1981 |
Studies in the mechanism of action of serotonin precursors in depression.
Topics: Depression; Humans; Protein Precursors; Serotonin; Tryptophan | 1984 |
Depression, suicide, and aggression in alcoholics and their relationship to plasma amino acids.
Topics: Adult; Aggression; Alcoholism; Amino Acids; Depression; Humans; Male; Middle Aged; Suicide, Attempted; Tryptophan | 1984 |
[Serotonin precursors as antidepressive agents: a review].
Topics: 5-Hydroxytryptophan; Climacteric; Depression; Depressive Disorder; Female; Humans; Tryptophan | 1983 |
New antidepressant drugs: a clinical perspective.
Topics: Antidepressive Agents; Depression; Humans; Levodopa; Tryptophan | 1984 |
Treatment of depression by altering monoamine metabolism: precursors and metabolic inhibitors.
Topics: Biogenic Amines; Catecholamines; Depression; Humans; Levodopa; Monoamine Oxidase Inhibitors; Serotonin; Tryptophan; Tyrosine | 1984 |
Nutritional precursors and the treatment of depression.
Topics: Brain; Depression; Humans; Norepinephrine; Serotonin; Tryptophan; Tyrosine | 1983 |
[Central serotonin metabolism in depression].
Topics: 5-Hydroxytryptophan; Affect; Brain; Depression; Humans; Longitudinal Studies; Probenecid; Serotonin; Tryptophan | 1980 |
[Biochemistry of depression. Comments and correction].
Topics: Brain Chemistry; Depression; Humans; Monoamine Oxidase; Tryptophan | 1982 |
Experiences with L-tryptophan in a child and family psychiatric department.
Topics: Adolescent; Anxiety; Child; Child Psychiatry; Depression; Female; Humans; Male; Stress, Physiological; Tryptophan | 1982 |
Brain availability of monoamine precursors in adult coeliac disease.
Topics: Adult; Aged; Brain; Caseins; Celiac Disease; Depression; Female; Humans; Male; Middle Aged; Tryptophan; Tyrosine | 1982 |
Serotonin metabolism and depression in oral contraceptive users.
Topics: Adult; Contraceptives, Oral; Depression; Female; Humans; Hydrocortisone; Monoamine Oxidase; Serotonin; Tryptophan | 1982 |
Cushing's syndrome, tryptophan and depression.
Topics: Adolescent; Adult; Aged; Cushing Syndrome; Depression; Female; Humans; Male; Middle Aged; Pituitary Neoplasms; Tryptophan | 1980 |
Effect of electroconvulsive therapy (ECT) on plasma tryptophan.
Topics: Adult; Depression; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Tryptophan | 1980 |
Tryptophan, cortisol and puerperal mood.
Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Depression; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Puerperal Disorders; Seasons; Time Factors; Tryptophan | 1980 |
[Biochemical depression].
Topics: Depression; Humans; Norepinephrine; Serotonin; Tryptophan | 1980 |
24h withdrawal following repeated administration of caffeine attenuates brain serotonin but not tryptophan in rat brain: implications for caffeine-induced depression.
Topics: Analysis of Variance; Animals; Brain; Caffeine; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan | 1995 |
[The amino acid tryptophan is unfit and risky in its use against depression].
Topics: Depression; Humans; Tryptophan | 1993 |
Effects of tryptophan and serotonin uptake inhibitors on behavior in male transgenic transforming growth factor alpha mice.
Topics: Aggression; Animals; Behavior, Animal; Clomipramine; Depression; Male; Mice; Mice, Transgenic; Selective Serotonin Reuptake Inhibitors; Swimming; Synaptic Transmission; Transforming Growth Factor alpha; Tryptophan; Zimeldine | 1993 |
Sequential administration of augmentation strategies in treatment-resistant obsessive-compulsive disorder: preliminary findings.
Topics: Adrenergic beta-Antagonists; Adult; Buspirone; Depression; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Obsessive-Compulsive Disorder; Pindolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptophan | 1996 |
Tryptophan and depression.
Topics: Affect; Depression; Depressive Disorder; Female; Humans; Recurrence; Serotonin; Tryptophan | 1997 |
Cancer cachexia and depressive states: a neuro-endocrine-immunological disease?
Topics: Adult; Aged; Aged, 80 and over; Biopterins; Cachexia; Depression; Female; Gastrointestinal Neoplasms; Humans; Hydrocortisone; Male; Middle Aged; Neopterin; Serotonin; Tryptophan | 1997 |
Differences in whole blood serotonin levels based on a typology of parasuicide.
Topics: Adult; Analysis of Variance; Biomarkers; Case-Control Studies; Depression; Female; Homovanillic Acid; Humans; Impulsive Behavior; Male; Motivation; Self-Injurious Behavior; Serotonin; Suicide, Attempted; Tryptophan | 1998 |
Influence of acute tryptophan depletion on mood and immune measures in healthy males.
Topics: Adolescent; Adult; Affect; Amino Acids; Cell Division; Depression; Fenfluramine; Humans; Interleukin-1; Interleukin-6; Lymphocyte Activation; Male; Psychological Tests; Psychoneuroimmunology; Serotonin; Single-Blind Method; Tryptophan | 1999 |
Relationships of plasma tryptophan availability to course of illness and clinical features of alcoholism: a preliminary study.
Topics: Age of Onset; Alcoholism; Amino Acids; Biological Availability; Depression; Disruptive, Impulse Control, and Conduct Disorders; Female; Hostility; Humans; Male; Mood Disorders; Serotonin; Tryptophan | 1999 |
Tryptophan depletion: a predictor of future depressive episodes in seasonal affective disorder?
Topics: Adult; Depression; Female; Forecasting; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Risk Assessment; Seasonal Affective Disorder; Seasons; Serotonin; Tryptophan | 1999 |
Fructose malabsorption is associated with decreased plasma tryptophan.
Topics: Adolescent; Adult; Breath Tests; Depression; Female; Fructose; Humans; Hydrogen; Intestinal Absorption; Malabsorption Syndromes; Male; Middle Aged; Reference Values; Tryptophan | 1999 |
Degradation of tryptophan in patients with systemic lupus erythematosus.
Topics: Depression; Humans; Kynurenine; Lupus Erythematosus, Systemic; Neopterin; Reference Values; Tryptophan | 1999 |
Does mirtazapine enhance serotonergic neurotransmission in depressed patients?
Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Prolactin; Serotonin; Synaptic Transmission; Tryptophan | 2000 |
Immune reaction links disease progression in cancer patients with depression.
Topics: Depression; Disease Progression; Humans; Neoplasms; Neopterin; Serotonin; Tryptophan | 2000 |
Depressive symptoms in hypothyroid disorder with some observations on biochemical correlates.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Depression; Humans; Hypothyroidism; Male; Middle Aged; Spinal Puncture; Tetragastrin; Thyroxine; Tryptophan | 2001 |
Acute antidepressant-like and antianxiety-like effects of tryptophan in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fenclonine; Male; Melatonin; Mice; Serotonin Antagonists; Tryptophan | 2001 |
Anxiogenic and depressive-like effects, but no cognitive deficits, after repeated moderate tryptophan depletion in the rat.
Topics: Animals; Anxiety; Attention; Body Weight; Cerebral Cortex; Cognition; Corticosterone; Depression; Food Preferences; Hippocampus; Male; Memory; Memory, Short-Term; Motor Activity; Rats; Rats, Wistar; Space Perception; Stress, Psychological; Swimming; Taste; Tryptophan | 2002 |
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study.
Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine | 2002 |
Pain, depression and phobia: a biochemical hypothesis.
Topics: Adrenocorticotropic Hormone; Aged; Anti-Anxiety Agents; Antidepressive Agents; Depression; Ethanol; Female; Glucocorticoids; Glutamates; Humans; Male; Middle Aged; Norepinephrine; Pain; Phobic Disorders; Serotonin; Tryptophan | 1976 |
[Fluorometric determination of free and total tryptophan in blood plasma].
Topics: Depression; Fluorometry; Heparin; Humans; Hydrogen-Ion Concentration; Protein Binding; Schizophrenia; Temperature; Tryptophan; Ultracentrifugation; Ultrafiltration | 1977 |
Letter: Tryptophan plus a pyrrolase inhibitor for depression?
Topics: Allopurinol; Brain; Depression; Drug Synergism; Drug Therapy, Combination; Humans; Niacinamide; Time Factors; Tryptophan | 1975 |
Letter: Treatment of unipolar depression.
Topics: Depression; Female; Humans; Tryptophan | 1975 |
Letter: Tryptophan plus a pyrrolase inhibitor for depression.
Topics: Allopurinol; Animals; Depression; Drug Synergism; Drug Therapy, Combination; Glucose; Humans; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase | 1975 |
Letter: Unipolar affective illness.
Topics: Brain; Brain Chemistry; Depression; Humans; Neurons; Tryptophan | 1976 |
Letter: Tryptophan and allopurinol in the treatment of depression.
Topics: Adult; Allopurinol; Depression; Drug Evaluation; Drug Therapy, Combination; Humans; Male; Middle Aged; Tryptophan | 1976 |
Total and non-bound tryptophan in unipolar illness.
Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Male; Middle Aged; Protein Binding; Tryptophan | 1976 |
Total and non-bound plasma-tryptophan in depressive illness.
Topics: Amitriptyline; Depression; Female; Humans; Male; Middle Aged; Protein Binding; Sex Factors; Tryptophan | 1977 |
Tryptophan in patients on chronic haemodialysis.
Topics: Adult; Dementia; Depression; Humans; Kidney Failure, Chronic; Middle Aged; Renal Dialysis; Tryptophan | 1977 |
Mechanism of the antidepressant action of electroconvulsive therapy.
Topics: Animals; Behavior, Animal; Brain; Bufotenin; Depression; Dopamine; Electroconvulsive Therapy; Evaluation Studies as Topic; Humans; Hydroxydopamines; Male; Norepinephrine; Rats; Serotonin; Tranylcypromine; Tryptophan | 1978 |
Drug-induced depression.
Topics: Antipsychotic Agents; Depression; Humans; Tranquilizing Agents; Tryptophan | 1978 |
Tryptophan and tyrosine availability and oral contraceptives.
Topics: Adult; Biological Availability; Brain; Contraceptives, Oral; Depression; Estradiol Congeners; Ethinyl Estradiol; Female; Humans; Tryptophan; Tyrosine | 1979 |
[Indoleamine precursors in depression (author's transl)].
Topics: Depression; Drug Therapy, Combination; Humans; Hydroxyindoleacetic Acid; Middle Aged; Monoamine Oxidase Inhibitors; Serotonin; Tryptophan | 1979 |
Tryptophan-nicotinamide combination in the treatment of newly admitted depressed patients.
Topics: Adult; Bipolar Disorder; Depression; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Niacinamide; Tryptophan | 1978 |
[Biochemistry of depression].
Topics: Adrenocorticotropic Hormone; Bipolar Disorder; Contraceptives, Oral; Cyclic AMP; Depression; Dopamine; Estrogens; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Norepinephrine; Serotonin; Triiodothyronine; Tryptophan | 1976 |
Cyclic AMP in cerebrospinal fluid of manic and depressive patients.
Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; Lithium; Methadone; Methyltyrosines; Physical Exertion; Probenecid; Tryptophan | 1977 |
Manipulation of neurotransmitters by acupuncture (?) (A preliminary communication).
Topics: Acupuncture Therapy; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Male; Middle Aged; Neurotransmitter Agents; Tryptophan; Tyrosine; Vanillic Acid; Vanilmandelic Acid | 1975 |
Tryptophan accumulation by blood platelets of depressed patients.
Topics: Biological Transport, Active; Blood Platelets; Depression; Female; Humans; Male; Tryptophan | 1979 |
Distribution of tryptophan in erythrocytes, leukocytes and thrombocytes, and its binding to plasma albumin.
Topics: Biological Transport, Active; Blood Platelets; Depression; Erythrocytes; Humans; Leukocytes; Schizophrenia; Serum Albumin; Tryptophan | 1979 |
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine | 1977 |
[Psychopharmacology of tryptophan (author's transl)].
Topics: Animals; Bipolar Disorder; Depression; Humans; Mental Disorders; Parkinson Disease; Schizophrenia; Serotonin; Sleep; Tryptophan | 1977 |
[Tryptophan. Peripheral regulation of central function].
Topics: Adrenal Cortex Hormones; Brain; Depression; Estrogens; Female; Humans; Pain; Pyridoxine; Serotonin; Sleep; Tryptophan | 1979 |
Depression: new evidence in support of biological differentiation.
Topics: Adult; Bipolar Disorder; Carbidopa; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Tryptamines; Tryptophan | 1979 |
Study of disturbed tryptophan metabolism in depressive illness.
Topics: Depression; Fatty Acids, Nonesterified; Humans; Intellectual Disability; Mental Disorders; Stress, Psychological; Tryptophan | 1979 |
Bimodal distribution of serum trypotphan level.
Topics: Adult; Age Factors; Depression; Electroconvulsive Therapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Suicide; Time Factors; Tryptophan | 1979 |
Tryptophan disposition in psychiatric patients before and after stress.
Topics: Adult; Depression; Fatty Acids, Nonesterified; Female; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Psychomotor Agitation; Stress, Physiological; Tryptophan | 1979 |
Mood changes in puerperium, and plasma tryptophan and cortisol concentrations.
Topics: Adolescent; Adult; Depression; Female; Humans; Hydrocortisone; Pregnancy; Psychiatric Status Rating Scales; Puerperal Disorders; Tryptophan | 1977 |
Processes regulating the functional activity of brain 5-hydroxytryptamine: results of animal experimentation and their relevance to the understanding and treatment of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Dopamine; gamma-Aminobutyric Acid; Humans; Monoamine Oxidase; Rats; Serotonin; Tranylcypromine; Tryptophan | 1978 |
L-tryptophan--a "natural" sedative?
Topics: Depression; Humans; Hypnotics and Sedatives; Tryptophan | 1977 |
Choice of antidepressants.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Flupenthixol; Humans; Lithium; Monoamine Oxidase Inhibitors; Tryptophan | 1977 |
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan | 1977 |
Enhancement of the antidepressant response to L-tryptophan by a liver pyrrolase inhibitor: a rational treatment approach.
Topics: Adult; Allopurinol; Depression; Drug Evaluation; Drug Therapy, Combination; Humans; Liver; Male; Middle Aged; Tryptophan; Tryptophan Oxygenase | 1978 |
L-tryptophan in the treatment of depressive illness.
Topics: Depression; Humans; Tryptophan | 1978 |
Tryptophan in depression.
Topics: Depression; Female; Humans; Tryptophan | 1978 |
Has tryptophan any anticonvulsive effect?
Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Depression; Drug Evaluation; Electroconvulsive Therapy; Electroencephalography; Female; Humans; Male; Middle Aged; Serotonin; Time Factors; Tryptophan | 1978 |
The effect of clofibrate on total and free plasma tryptophan in depressed patients.
Topics: Blood Proteins; Clofibrate; Depression; Fatty Acids, Nonesterified; Female; Humans; Male; Protein Binding; Serum Albumin; Time Factors; Tryptophan | 1978 |
[Tryptophan, a stimulant amino acid].
Topics: Depression; Drug Evaluation; Humans; Pain; Sleep Wake Disorders; Tryptophan | 1978 |
Decreased tryptophan excretion by depressive patients.
Topics: Antidepressive Agents, Tricyclic; Depression; Female; Humans; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 1978 |
Multicompartmental analysis of amino acids: II. Tryptophan in affective disorder.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depression; Female; Humans; Kinetics; Lithium; Male; Middle Aged; Protein Binding; Sex Factors; Stress, Psychological; Tryptophan | 1978 |
Depression in the elderly.
Topics: Aged; Antidepressive Agents, Tricyclic; Brain; Catecholamines; Dementia; Depression; Humans; Hypochondriasis; Life Change Events; Pain; Psychotherapy; Terminal Care; Tryptophan | 1978 |
Prostaglandin F in patients with primary affective disorder.
Topics: Adult; Aged; Bipolar Disorder; Depression; Female; Humans; Male; Middle Aged; Probenecid; Prostaglandins F; Tryptophan | 1977 |
Relationship between mood disturbances and free and total plasma tryptophan in postpartum women.
Topics: Depression; Female; Humans; Postpartum Period; Pregnancy; Tryptophan | 1976 |
Tricyclic antidepressants, tryptophan and affective disorder.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Desipramine; Humans; Serotonin; Tryptophan | 1976 |
Plasma total and free tryptophan concentration in 'neurotic' and 'psychotic' depressive patients.
Topics: Adjustment Disorders; Adult; Depression; Diet; Female; Humans; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Tryptophan | 1976 |
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Obsessive-Compulsive Disorder; Phenylacetates; Schizophrenia; Tryptophan; Tyrosine | 1976 |
Total and free plasma tryptophan levels in patients with affective disorders: effects of a peripheral decarboxylase inhibitor.
Topics: Adolescent; Adult; Bipolar Disorder; Carbidopa; Depression; Female; Humans; Hydrazines; Male; Middle Aged; Tryptophan | 1976 |
The effect of tryptophan and a tryptophan/5-hydroxytryptophan combination on indoles in the brains of rats fed a tryptophan deficient diet.
Topics: 3-Hydroxyanthranilic Acid; 5-Hydroxytryptophan; Animals; Brain; Depression; Diet; Drug Synergism; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1975 |
Theoretical and therapeutic potential of indoleamine precursors. (1). Introduction.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Animals; Biogenic Amines; Depression; Diagnosis, Differential; Humans; Indoles; Serotonin; Tryptamines; Tryptophan | 1976 |
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania.
Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Imipramine; Lithium; Methysergide; Monoamine Oxidase Inhibitors; Phenylalanine; Probenecid; Serotonin; Tryptophan | 1975 |
[News from the control of thoughts].
Topics: Central Nervous System; Cognition; Depression; Humans; Hypothyroidism; Lithium; Reserpine; Tryptophan | 1975 |
Multicompartmental analysis of amino acid. 1. Preliminary data on concentrations, fluxes, and flow constants of tryptophan in affective illness.
Topics: Antidepressive Agents, Tricyclic; Biological Transport; Bipolar Disorder; Depression; Depression, Chemical; Female; Humans; Lithium; Male; Remission, Spontaneous; Sex Factors; Tryptophan | 1975 |
Biochemical post-mortem findings in depressed patients.
Topics: Aged; Brain Chemistry; Brain Mapping; Circadian Rhythm; Depression; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Norepinephrine; Remission, Spontaneous; Serotonin; Tryptophan; Tyrosine; Vanilmandelic Acid | 1975 |
Plasma tryptophan transport in normal and depressed subjects.
Topics: Depression; Humans; Injections, Intravenous; Male; Time Factors; Tryptophan | 1975 |
[Biochemical findings in the brain in endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Catecholamines; Depression; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; Norepinephrine; Serotonin; Tryptophan | 1975 |
[Sleep deprivation. Clinical ratings, psychophysiological and biochemical measures (author's transl)].
Topics: Adult; Aged; Depression; Electroencephalography; Female; Heart Rate; Humans; Male; Middle Aged; Respiration; Sleep Deprivation; Stress, Psychological; Tryptophan; Tyrosine | 1975 |
[Hormonal contraception, tryptophan metabolism and depression].
Topics: Contraceptives, Oral; Depression; Female; Humans; Kynurenic Acid; Pyridoxine; Tryptophan; Xanthurenates | 1975 |
Plasma tryptophan concentration in depressive illness and mania.
Topics: Adult; Bipolar Disorder; Depression; Dietary Proteins; Humans; Middle Aged; Nitrazepam; Remission, Spontaneous; Tryptophan | 1976 |
Concentration of 5-hydroxyindoleacetic acid, homovanillic acid, and tryptophan in the cerebrospinal fluid of depressed patients before and after ECT.
Topics: Adult; Brain; Depression; Electroconvulsive Therapy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Psychiatric Status Rating Scales; Time Factors; Tryptophan | 1976 |
Neuroendocrine responses to L-tryptophan as an index of brain serotonin function: effect of weight loss.
Topics: Adult; Biological Transport, Active; Brain Chemistry; Clomipramine; Depression; Diet, Reducing; Female; Granisetron; Growth Hormone; Humans; Hydroxyindoleacetic Acid; Indazoles; Infusions, Intravenous; Male; Metergoline; Metoclopramide; Neurosecretory Systems; Prolactin; Ritanserin; Serotonin; Sex Characteristics; Synaptic Transmission; Thyrotropin-Releasing Hormone; Tryptophan; Tryptophan Hydroxylase; Weight Loss | 1991 |
Plasma free 5HT and platelet 5HT in depression: case-control studies and the effect of antidepressant therapy.
Topics: Antidepressive Agents; Bipolar Disorder; Blood Platelets; Case-Control Studies; Depression; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Lithium; Male; Monoamine Oxidase Inhibitors; Serotonin; Tryptophan | 1991 |
Effects of tryptophan on depression and aggression in STZ-D mice.
Topics: Aggression; Analysis of Variance; Animals; Depression; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred Strains; Motor Activity; Reference Values; Social Behavior; Tryptophan | 1991 |
Plasma precursor amino acids of central nervous system monoamines in children with coeliac disease.
Topics: Adolescent; Amino Acids; Biogenic Monoamines; Brain; Celiac Disease; Child; Child, Preschool; Depression; Humans; Tryptophan; Tyrosine | 1991 |
Symptom profiles of biological markers in depression: a multivariate study.
Topics: Adult; Aged; Biomarkers; Depression; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middle Aged; Multivariate Analysis; Statistics as Topic; Thyrotropin; Thyrotropin-Releasing Hormone; Tryptophan | 1990 |
The decreased availability of L-tryptophan in depressed females: clinical and biological correlates.
Topics: Adrenocorticotropic Hormone; Adult; Amino Acids; Analysis of Variance; Depression; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Middle Aged; Multivariate Analysis; Norepinephrine; Regression Analysis; Thyroxine; Triiodothyronine; Tryptophan; Vanilmandelic Acid | 1990 |
[Current status, perspectives and limitations of serotonin precursors].
Topics: 5-Hydroxytryptophan; Central Nervous System; Depression; Humans; Serotonin; Sleep; Tryptophan | 1990 |
Platelet serotonin content and plasma tryptophan in peri- and postmenopausal women: variations with plasma oestrogen levels and depressive symptoms.
Topics: Blood Platelets; Depression; Estrogens; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Menopause; Middle Aged; Serotonin; Tryptophan | 1988 |
Precursor amino acid concentrations in normal weight bulimics and normal controls.
Topics: Adult; Body Weight; Bulimia; Depression; Female; Humans; Reference Values; Serotonin; Tryptophan | 1988 |
Effects of trazodone treatment on serotonergic function in depressed patients.
Topics: Adult; Affect; Aged; Blood Pressure; Depression; Female; Growth Hormone; Humans; Male; Middle Aged; Prolactin; Serotonin; Time Factors; Trazodone; Tryptophan | 1988 |
Whole blood serotonin and plasma tryptophan using high-pressure liquid chromatography with electrochemical detection.
Topics: Adult; Blood Platelets; Chromatography, High Pressure Liquid; Depression; Electrochemistry; Female; Humans; Male; Plasma; Serotonin; Tryptophan | 1987 |
Neuroendocrine responses to intravenous tryptophan in major depression.
Topics: Adult; Aged; Benzodiazepines; Depression; Female; Growth Hormone; Humans; Hydrocortisone; Injections, Intravenous; Male; Middle Aged; Neurosecretory Systems; Osmolar Concentration; Prolactin; Sleep Stages; Tryptophan | 1987 |
A multivariate investigation of postpartum mood disturbance.
Topics: Adolescent; Adult; Affective Symptoms; Crying; Depression; Fatty Acids, Nonesterified; Female; Humans; Parity; Pregnancy; Puerperal Disorders; Tryptophan | 1986 |
Plasma neutral amino acids and food preferences: possible implications in normals and depressives.
Topics: Amino Acids; Depression; Diet; Food Preferences; Humans; Reference Values; Sleep; Tryptophan | 1986 |
Uptake of tryptophan into the brain: dietary influences on serotoninergic function.
Topics: Animals; Appetite Regulation; Brain; Depression; Diet; Humans; Kinetics; Protein Binding; Pyridoxine; Serotonin; Serum Albumin; Tryptophan | 1986 |
Plasma tryptophan, age and depression.
Topics: Adolescent; Adult; Aged; Aging; Depression; Female; Humans; Male; Middle Aged; Serum Albumin; Tryptophan | 1985 |
Pharmacological strategies in depression.
Topics: Antidepressive Agents, Tricyclic; Carbamazepine; Depression; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Monoamine Oxidase Inhibitors; Triiodothyronine; Tryptophan; Vanadium | 1985 |
Levodopa and depression in parkinsonism.
Topics: Depression; Dihydroxyphenylalanine; Drug Synergism; Humans; Parkinson Disease; Tryptophan | 1971 |
Total and free tryptophan concentration in the plasma of depressive patients.
Topics: Adult; Depression; Female; Humans; Middle Aged; Tryptophan | 1972 |
Total and free tryptophan concentration in the plasma of depressive patients.
Topics: Acids; Brain; Depression; Fatty Acids, Nonesterified; Female; Humans; Hydroxyindoleacetic Acid; Lithium; Middle Aged; Monoamine Oxidase Inhibitors; Solubility; Stimulation, Chemical; Tryptophan | 1973 |
Letter: Total and free plasma-tryptophan concentration and oral contraception.
Topics: Brain; Contraceptives, Oral; Depression; Female; Humans; Tryptophan; Vitamin B 6 Deficiency | 1973 |
Letter: Plasma-tryptophan and oral contraceptives.
Topics: Brain; Contraceptives, Oral; Depression; Female; Humans; Serotonin; Tryptophan | 1974 |
Antidepressant action of tryptophan.
Topics: Animals; Antidepressive Agents; Brain; Depression; Drug Antagonism; Humans; Nicotinic Acids; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1974 |
Letter: Tryptophan in depression.
Topics: Depression; Humans; Methoxyhydroxyphenylglycol; Tryptophan | 1974 |
Letter: Tryptophan plus a pyrrolase inhibitor for depression?
Topics: Adult; Allopurinol; Animals; Depression; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; In Vitro Techniques; Niacinamide; Rats; Tryptophan; Tryptophan Oxygenase | 1974 |
Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the cerebrospinal fluid of patients with affective illness.
Topics: Adult; Affective Symptoms; Antipsychotic Agents; Biogenic Amines; Bipolar Disorder; Butyrophenones; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenothiazines; Receptors, Drug; Serotonin; Tryptophan | 1973 |
Tryptophan in the treatment of depression.
Topics: Carbohydrates; Depression; Electroconvulsive Therapy; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Potassium; Tranylcypromine; Tryptophan | 1967 |
Preventing depression with tryptophan.
Topics: Depression; Female; Humans; Middle Aged; Tryptophan | 1968 |
Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect.
Topics: Adrenal Cortex Hormones; Animals; Antidepressive Agents; Brain; Brain Chemistry; Depression; Drug Synergism; Electroshock; Humans; Imipramine; Kynurenine; Liver; Monoamine Oxidase Inhibitors; Serotonin; Serotonin Antagonists; Tranquilizing Agents; Tryptophan; Tryptophan Oxygenase | 1969 |
Oral contraceptives and depression.
Topics: Contraceptives, Oral; Depression; Female; Humans; Menstruation; Pregnancy; Pyridoxine; Tryptophan | 1969 |
Oral contraceptives and depression.
Topics: Contraceptives, Oral; Depression; Female; Humans; Pyridoxine; Tryptophan | 1969 |
Metabolic changes in depression.
Topics: Animals; Betamethasone; Brain; Depression; Humans; Pituitary-Adrenal System; Serotonin; Tryptophan | 1969 |
Pyridoxine and the pill.
Topics: Adult; Contraceptives, Oral; Depression; Emotions; Ethynodiol Diacetate; Fatigue; Female; Humans; Lynestrenol; Pregnancy; Pyridoxine; Sleep Wake Disorders; Tryptophan; Vitamin B 6 Deficiency | 1970 |
Oral contraceptives, depression, and aminoacid metabolism.
Topics: Alanine Transaminase; Animals; Contraceptives, Oral; Depression; Estradiol; Female; Humans; Liver; Rats; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase | 1970 |
L-tryptophan in depression.
Topics: Depression; Electroconvulsive Therapy; Humans; Tryptophan | 1970 |
L-tryptophan versus E.C.T.
Topics: Depression; Electroconvulsive Therapy; Humans; Tablets; Tryptophan | 1970 |
L-tryptophan verses E.C.T.
Topics: Depression; Electroconvulsive Therapy; Humans; Tryptophan | 1970 |
L-tryptophan in depression.
Topics: Brain; Depression; Humans; Serotonin; Tryptophan | 1970 |
L-tryptophan in depression.
Topics: Depression; Humans; Tryptophan | 1970 |
Selecting the optimum oral contraceptive.
Topics: Acne Vulgaris; Blood Coagulation Disorders; Brain Edema; Breast; Candidiasis; Capillaries; Carbohydrate Metabolism; Contraceptives, Oral; Depression; Edema; Fatigue; Female; Hair; Hirsutism; Humans; Hypertension; Lipid Metabolism; Menstruation; Migraine Disorders; Nausea; Progestins; Seizures; Triiodothyronine; Tryptophan | 1973 |
Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Depression; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Probenecid; Serotonin; Spinal Puncture; Time Factors; Tryptophan | 1974 |
Serotonin now: clinical implications of inhibiting its synthesis with para-chlorophenylalanine.
Topics: Adult; Aged; Animals; Behavior; Brain Chemistry; Catechols; Cattle; Depression; Diarrhea; Dogs; Enzyme Precursors; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Rabbits; Rats; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Sleep, REM; Testosterone; Tryptophan; Vasomotor System | 1970 |
Amine precursors, amines, and false neurotransmitters in depressed patients.
Topics: Biogenic Amines; Biological Transport; Blood Platelets; Carbon Isotopes; Depression; Dihydroxyphenylalanine; Dopamine; Humans; Serotonin; Synaptic Transmission; Tryptophan | 1972 |
The effect of lithium carbonate on the sleep of depressed patients.
Topics: Adult; Carbonates; Depression; Electroencephalography; Humans; Lithium; Middle Aged; Sleep; Sleep Stages; Sleep, REM; Time Factors; Tryptophan | 1973 |
Therapy-resistant depressions. Biochemical and pharmacological considerations. Contributions to biochemistry.
Topics: Antidepressive Agents; Brain; Depression; Dopamine; Drug Resistance; Histocytochemistry; Humans; Monoamine Oxidase; Norepinephrine; Serotonin; Suicide; Tryptophan | 1974 |
Fluorometric measurement of 5-hydroxyindoleacetic acid (5HIAA) and tryptophan in human CSF: effects of high doses of probenecid.
Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Depression; Female; Fluorometry; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Schizophrenia; Tryptophan | 1974 |
Treatment of intractable depression.
Topics: Amantadine; Antidepressive Agents; Depression; Dextroamphetamine; Drug Therapy, Combination; Hormones; Humans; Lithium; Methylphenidate; Monoamine Oxidase Inhibitors; Reserpine; Sleep Deprivation; Tryptophan; Vitamins | 1974 |
Plasma tryptophan tolerance curves in drug free normal controls, schizophrenic patients and prisoner volunteers.
Topics: Acute Disease; Administration, Oral; Adult; Chlorpromazine; Chronic Disease; Circadian Rhythm; Depression; Fasting; Food; Half-Life; Humans; Male; Middle Aged; Personality Disorders; Prisoners; Schizophrenia; Tryptophan | 1974 |
[Tryptophane and affective disorders (author's transl)].
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Depression; Humans; Serotonin; Tryptophan | 1974 |
Proceedings: Amine precursors in depression: studies combining L-DOPA and L-tryptophan.
Topics: Animals; Depression; Humans; Levodopa; Tryptophan | 1974 |
Depression induced by oral contraception and the role of vitamin B6 in its management.
Topics: 5-Hydroxytryptophan; Contraceptives, Oral; Depression; Female; Humans; Pyridoxine; Serotonin; Tryptophan; Vitamin B 6 Deficiency | 1974 |
[Studies of indolamine metabolites in cerebrospinal fluid in depression].
Topics: Depression; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indomethacin; Male; Mass Spectrometry; Tryptamines; Tryptophan | 1972 |
Experimental data to the pathogenesis of cryptopyrrole excretion in schizophrenia, I.
Topics: Chromatography; Depression; Epilepsy; Humans; Mass Screening; Paranoid Disorders; Periodicity; Porphyrins; Psychotic Disorders; Pyrroles; Schizophrenia; Tryptophan | 1972 |
Low plasma tryptophan levels in recently hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Chronic Disease; Depression; Diet; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Schizophrenia; Sex Factors; Tryptophan; Tyrosine | 1973 |
The tyrosine-tryptophan-diagram in a longtime study with depressed patients.
Topics: Catecholamines; Depression; Humans; Indoles; Tryptophan; Tyrosine | 1973 |
Influence of affective states and psychoactive drugs on verbal learning and memory.
Topics: Bipolar Disorder; Carbonates; Depression; Dihydroxyphenylalanine; Humans; Imipramine; Lithium; Memory; Methyltyrosines; Serial Learning; Tryptophan; Verbal Learning; Word Association Tests | 1973 |
5-Hydroxytryptamine metabolism in affective illness: the effect of tryptophan administration.
Topics: Adult; Affective Symptoms; Age Factors; Aged; Bipolar Disorder; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Tryptophan; Tryptophan Hydroxylase | 1973 |
Metabolism of tryptophan in depressive disease.
Topics: Adult; Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Metabolic Clearance Rate; Middle Aged; Personality Disorders; Pyridoxine; Tryptamines; Tryptophan | 1973 |
Tryptophan concentration in serum of patients with regional enteritis. Its possible relation to depression.
Topics: Antidepressive Agents; Crohn Disease; Depression; Feces; Fluorometry; Humans; Lipids; Pilot Projects; Tryptophan | 1973 |
5-Hydroxyindoleacetic acid in cerebrospinal fluid.
Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Middle Aged; Neurocognitive Disorders; Paralysis; Parkinson Disease; Probenecid; Spectrometry, Fluorescence; Spinal Cord Compression; Tabes Dorsalis; Tryptophan | 1973 |
Oral contraceptives, pyridoxine, and depression.
Topics: Animals; Brain Chemistry; Contraceptives, Oral; Depression; Estrogens; Female; Humans; Kynurenine; Nicotinic Acids; Norepinephrine; Pregnancy; Premenstrual Syndrome; Pyridoxine; Serotonin; Tryptophan; Vitamin B 6 Deficiency | 1973 |
Tryptophan metabolism in depressive illness.
Topics: Blood Proteins; Carbon Radioisotopes; Depression; Electroconvulsive Therapy; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Injections, Intravenous; Male; Middle Aged; Protein Binding; Tryptophan | 1974 |
[Statistical aspects of the tyrosine-tryptophan diagram in depression (author's transl)].
Topics: Depression; Follow-Up Studies; Humans; Psychiatric Status Rating Scales; Remission, Spontaneous; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1974 |
Plasma tryptophan binding and depression.
Topics: Depression; Female; Humans; Lithium; Middle Aged; Protein Binding; Tryptophan | 1974 |
Toward a biochemical classification of depression.
Topics: Antidepressive Agents; Biogenic Amines; Brain; Brain Stem; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Norepinephrine; Nortriptyline; Probenecid; Receptors, Drug; Serotonin; Sleep Deprivation; Spinal Cord; Suicide; Tryptophan | 1974 |
Abnormalities of indoleamines in affective disorders.
Topics: Adult; Affective Symptoms; Biogenic Amines; Brain Chemistry; Depression; Drug Combinations; Evaluation Studies as Topic; Female; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Middle Aged; Serotonin; Spinal Puncture; Tranylcypromine; Tryptophan | 1972 |
Combined therapy of E.C.T. and amitriptyline and L-tryptophan in the treatment of severe depression.
Topics: Amitriptyline; Deficiency Diseases; Depression; Electroconvulsive Therapy; Humans; Liver Function Tests; Male; Middle Aged; Tryptophan; Uric Acid | 1972 |
Indoleamine metabolism in affective disorders: excretion of tryptamine, indoleacetic acid and 5-hydroxy-indoleacetic acid in depressive states.
Topics: Adult; Affective Symptoms; Aged; Creatine; Depression; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Middle Aged; Tryptamines; Tryptophan | 1972 |
Indole metabolism and behavior in dog.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Brain; Brain Chemistry; Depression; Disease Models, Animal; Dogs; Electrodes, Implanted; Electroencephalography; Evaluation Studies as Topic; Female; Housing, Animal; Humans; Indoles; Male; Portacaval Shunt, Surgical; Tranylcypromine; Tryptophan | 1972 |
L-tryptophan and depressive illness.
Topics: Depression; Humans; Sleep; Tryptophan | 1972 |
Serotonin and severe affective disorders.
Topics: Affective Symptoms; Biogenic Amines; Brain Chemistry; Depression; Humans; Hydroxyindoleacetic Acid; Serotonin; Tryptophan | 1971 |
Depressed states and indolealkylamines.
Topics: 5-Hydroxytryptophan; Carbon Isotopes; Catecholamines; Depression; Humans; Indoles; Middle Aged; Monoamine Oxidase Inhibitors; Serotonin; Tryptamines; Tryptophan | 1968 |
Tryptophan pyrrolase and depressive illness.
Topics: 5-Hydroxytryptophan; Depression; Humans; Hydroxyindoleacetic Acid; Psychiatric Status Rating Scales; Tryptophan; Tryptophan Oxygenase | 1970 |
Amine metabolism in brain.
Topics: Amines; Animals; Brain; Cerebral Cortex; Depression; Dogs; Dopamine; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Tryptophan | 1969 |
Oral contraceptives and depression.
Topics: Chorea; Contraceptives, Oral; Depression; Female; Humans; Tryptophan | 1970 |
Tryptophan metabolism in depression.
Topics: Administration, Oral; Adult; Depression; Female; Humans; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Sex Factors; Tryptophan | 1970 |
Cerebrospinal fluid 5-hydroxyindoles and behavior after L-tryptophan and pyridoxine adminstration to psychiatric patients.
Topics: Adolescent; Adult; Behavior; Depression; Female; Humans; Indoles; Male; Middle Aged; Psychological Tests; Pyridoxine; Schizophrenia; Tryptophan | 1970 |
[Disturbance of tyrosine and tryptophane metabolism in depression].
Topics: Adolescent; Adult; Circadian Rhythm; Depression; Female; Humans; Kynurenine; Male; Middle Aged; Tryptophan; Tyrosine | 1970 |
[Clinical examples of tryptophan metabolism disorders].
Topics: Crohn Disease; Depression; Humans; Male; Physical Exertion; Tryptophan | 1971 |
[Deficit of essential amino acids in endogenous depression].
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Female; Humans; Injections, Intravenous; Male; Middle Aged; Phenylalanine; Tryptophan; Tyrosine | 1968 |
[Tryptophan metabolism during depression].
Topics: Amitriptyline; Depression; Female; Humans; Hydrazines; Imipramine; Male; Serotonin; Tranylcypromine; Tryptophan | 1968 |
Recent studies of severe depressive illnesses. 2.
Topics: Catecholamines; Depression; Humans; Serotonin; Tryptophan | 1969 |
Screening for aminoacidurias in psychiatric inpatients.
Topics: Affective Symptoms; Amino Acid Metabolism, Inborn Errors; Brain Damage, Chronic; Depression; Drug Synergism; Hartnup Disease; Homocystinuria; Hospitals, Psychiatric; Humans; Intellectual Disability; Mass Screening; Massachusetts; Mental Disorders; Methionine; Monoamine Oxidase Inhibitors; Neurotic Disorders; Personality Disorders; Phenylketonurias; Schizophrenia; Substance-Related Disorders; Tryptophan | 1969 |
Biochemical aspects of depression.
Topics: Adrenal Glands; Brain Chemistry; Depression; Dopamine; Electrolytes; Epinephrine; Extracellular Space; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Lithium; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Premenstrual Syndrome; Reserpine; Serotonin; Suicide; Thyroid Gland; Tryptamines; Tryptophan | 1969 |
Tryptamine metabolism in depression.
Topics: Adult; Aged; Depression; Electroconvulsive Therapy; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Tranylcypromine; Tryptamines; Tryptophan; Urine | 1965 |