choline has been researched along with Depression in 45 studies
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with elevated levels of choline and betaine had a lower risk of depression after acute ischemic stroke, suggesting the protective significance of choline pathway nutrients for PSD." | 9.51 | Circulating choline pathway nutrients and depression after ischemic stroke. ( Che, B; Du, J; Guo, Y; Ju, Z; Miao, M; Xu, T; Zhang, J; Zhang, Y; Zhong, C; Zhong, X, 2022) |
| "We have investigated proton magnetic resonance spectra of the basal ganglia in 41 medication-free outpatients with major depression, prior to starting an 8-week standardized trial of open-label fluoxetine, and 22 matched comparison subjects." | 9.08 | Basal ganglia choline levels in depression and response to fluoxetine treatment: an in vivo proton magnetic resonance spectroscopy study. ( Babb, SM; Bonello, CM; Christensen, JD; Cohen, BM; Fava, M; Lafer, B; Moore, CM; Nierenberg, AA; Pillay, SS; Renshaw, PF; Rosenbaum, JF; Rothschild, AJ; Stoll, AL; Yurgelun-Todd, DA, 1997) |
| "This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations." | 7.85 | Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017) |
| "We examined the cross-sectional association between plasma choline concentrations and scores of anxiety and depression symptoms in a general population sample." | 7.75 | Choline in anxiety and depression: the Hordaland Health Study. ( Bjelland, I; Konstantinova, S; Tell, GS; Ueland, PM; Vollset, SE, 2009) |
| "Patients with elevated levels of choline and betaine had a lower risk of depression after acute ischemic stroke, suggesting the protective significance of choline pathway nutrients for PSD." | 5.51 | Circulating choline pathway nutrients and depression after ischemic stroke. ( Che, B; Du, J; Guo, Y; Ju, Z; Miao, M; Xu, T; Zhang, J; Zhang, Y; Zhong, C; Zhong, X, 2022) |
| " The levels of total choline (tCho) and the tCho/N-acetyl aspartate (NAA) ratio were consistently higher in the brains of patients with depression, and that the levels of NAA, glutamate and glutamine (Glx), and gamma-aminobutyric acid (GABA) were lower." | 4.31 | Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies. ( Hu, L; Liu, Y; Lv, F; Ma, L; Pu, J; Shen, Y; Shi, Y; Xie, X; Yang, W; Zhang, H, 2023) |
| " Pain, depression, and emotional components of QOL in patients with CP correlated with N-acetyl aspartate and choline in the left hippocampus and left prefrontal cortex of the brain." | 4.12 | Pain, depression, and poor quality of life in chronic pancreatitis: Relationship with altered brain metabolites. ( Bedarkar, AP; Dhagudu, N; Hazarika, D; Jakkampudi, A; M, R; Pandol, SJ; Prasanna, A; Reddy, DN; Sarkar, P; Sarkar, S; Talukdar, R; Unnisa, M, 2022) |
| " The data with scopolamine are consistent with the adrenergic/cholinergic hypothesis of mania/depression derived from clinical reports originating in the 1970s from Janowsky and colleagues." | 3.96 | Involvement of muscarinic receptor mechanisms in antidepressant drug action. ( Brooks, EA; Golani, LK; Martin, AE; Smith, JL; Witkin, JM, 2020) |
| "This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations." | 3.85 | Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017) |
| " Concentrations of glutamate + glutamin (Glx), cholin (Cho), myoinositol (mIns), N-acetyl aspartate (NAA) expressed as ratio with creatine (Cr) and NAA were correlated with markers of disease activity (RIO score), Multiple Sclerosis Severity Scale (MSSS), Depressive-Severity Status Scale and Simple Numerical Fatigue Scale." | 3.85 | Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. ( Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K, 2017) |
| "Patients with first-episode depression may have myo-inositol and phosphoric acid metabolism disorder in the thalamus and hypothalamus with malfunction of cellular osmotic pressure adjustment mechanism." | 3.75 | [Proton magnetic resonance spectroscopy of the thalamus and hypothalamus in patients with first-episode depression]. ( Bai, XY; Ning, WD; Wu, XP; Xie, ZC; Yang, JL; Yang, R, 2009) |
| "To identify possible alterations in orbitofrontal cortex levels of cytosolic choline in adolescents with and without depression, 22 depressed and 43 control adolescents were recruited." | 3.70 | Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy. ( Beardslee, WR; Hennen, J; Katic, A; Moore, CM; Moore, JC; Renshaw, PF; Steingard, RJ; Vakili, K; Young, AD; Yurgelun-Todd, DA, 2000) |
| " In the study of the dose-response relationship, an L-shaped relationship between dietary choline and depressive symptoms was found." | 1.72 | Dietary choline is inversely associated with depressive symptoms: A cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2011 to 2018. ( Kang, X; Li, J; Luo, J; Zhang, D; Zhang, L, 2022) |
| "Twenty patients had depression recurrence, and 23 patients reached AD discontinuation." | 1.62 | Choline elevation in amygdala region at recovery indicates longer survival without depressive episode: a magnetic resonance spectroscopy study. ( Bajs Janović, M; Erdeljić Turk, V; Foro, T; Henigsberg, N; Hrabač, P; Kalember, P; Ozretić, D; Radoš, M; Šarac, H; Savić, A; Šečić, A, 2021) |
| "Depression is associated with structural and neurochemical changes in limbic structures, including the hippocampus, that control emotion and mood." | 1.39 | Phospholipase D-mTOR signaling is compromised in a rat model of depression. ( Feng, P; Huang, C, 2013) |
| "Agitation and depression are among the commonest behavioural and psychological symptoms exhibited by Alzheimer's disease patients." | 1.39 | Differences in brain metabolism associated with agitation and depression in Alzheimer's disease. ( Fuh, JL; Hung, CW; Lirng, JF; Tsai, CF; Wang, SJ, 2013) |
| "A well-validated animal model of treatment resistant depression (congenital learned helpless rats = cLH) was investigated by hippocampal in vivo ¹H MRS with and without a 1-week course of electroconvulsive shocks (ECS), an animal model of ECT, and compared to wild type (WT) animals, while saline and clomipramine injections served as additional controls." | 1.38 | Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression. ( Biedermann, S; Ende, G; Gass, P; Hoyer, C; Sartorius, A; Vollmayr, B; Weber-Fahr, W; Zheng, L, 2012) |
| "Moreover, depression was significantly correlated with titers of autoantibodies against DNA, NMDA receptors and cardiolipin." | 1.35 | Depression is an early disease manifestation in lupus-prone MRL/lpr mice. ( Campbell, SR; Cui, MH; Gao, HX; Gulinello, M; Hee-Hwang, J; Putterman, C; Zong, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (17.78) | 18.7374 |
| 1990's | 1 (2.22) | 18.2507 |
| 2000's | 11 (24.44) | 29.6817 |
| 2010's | 15 (33.33) | 24.3611 |
| 2020's | 10 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Miao, M | 1 |
| Du, J | 1 |
| Che, B | 1 |
| Guo, Y | 1 |
| Zhang, J | 1 |
| Ju, Z | 1 |
| Xu, T | 1 |
| Zhong, X | 1 |
| Zhang, Y | 1 |
| Zhong, C | 1 |
| Arcadi, FA | 1 |
| Corallo, F | 1 |
| Torrisi, M | 1 |
| Scarfì, C | 1 |
| Lo Buono, V | 1 |
| Formica, C | 1 |
| Bramanti, P | 1 |
| Marino, S | 1 |
| Bonanno, L | 1 |
| De Cola, MC | 1 |
| Li, J | 1 |
| Kang, X | 1 |
| Zhang, L | 3 |
| Luo, J | 1 |
| Zhang, D | 1 |
| Sarkar, S | 1 |
| Sarkar, P | 1 |
| M, R | 1 |
| Hazarika, D | 1 |
| Prasanna, A | 1 |
| Pandol, SJ | 1 |
| Unnisa, M | 1 |
| Jakkampudi, A | 1 |
| Bedarkar, AP | 1 |
| Dhagudu, N | 1 |
| Reddy, DN | 1 |
| Talukdar, R | 1 |
| Guath, M | 1 |
| Kleberg, JL | 1 |
| Weis, J | 1 |
| Widegren, E | 1 |
| Frick, M | 1 |
| Möller, S | 1 |
| Klevebrant, L | 1 |
| Karlsson, B | 1 |
| Fällmar, D | 1 |
| Mårtensson, J | 1 |
| Pine, DS | 1 |
| Brocki, K | 1 |
| Gingnell, M | 1 |
| Frick, A | 1 |
| Xie, X | 2 |
| Shi, Y | 2 |
| Ma, L | 2 |
| Yang, W | 2 |
| Pu, J | 2 |
| Shen, Y | 2 |
| Liu, Y | 2 |
| Zhang, H | 2 |
| Lv, F | 2 |
| Hu, L | 2 |
| Henigsberg, N | 1 |
| Savić, A | 1 |
| Radoš, M | 2 |
| Šarac, H | 1 |
| Šečić, A | 1 |
| Bajs Janović, M | 1 |
| Foro, T | 1 |
| Ozretić, D | 1 |
| Erdeljić Turk, V | 1 |
| Hrabač, P | 1 |
| Kalember, P | 1 |
| Wang, J | 1 |
| Zhou, T | 1 |
| Liu, J | 1 |
| Shangguan, J | 1 |
| Liu, X | 1 |
| Li, Z | 1 |
| Zhou, X | 1 |
| Ren, Y | 1 |
| Wang, C | 1 |
| Witkin, JM | 1 |
| Smith, JL | 1 |
| Golani, LK | 1 |
| Brooks, EA | 1 |
| Martin, AE | 1 |
| Drevets, WC | 1 |
| Bhattacharya, A | 1 |
| Furey, ML | 1 |
| van Lee, L | 1 |
| Quah, PL | 1 |
| Saw, SM | 1 |
| Yap, FKP | 1 |
| Godfrey, KM | 1 |
| Chong, YS | 1 |
| Meaney, MJ | 1 |
| Chen, H | 1 |
| Chong, MF | 1 |
| Freed, RD | 1 |
| Hollenhorst, CN | 1 |
| Weiduschat, N | 1 |
| Mao, X | 1 |
| Kang, G | 1 |
| Shungu, DC | 1 |
| Gabbay, V | 2 |
| Sekar, S | 1 |
| Grandjean, J | 1 |
| Garnell, JF | 1 |
| Willems, R | 1 |
| Duytschaever, H | 1 |
| Seramani, S | 1 |
| Su, H | 1 |
| Ver Donck, L | 1 |
| Bhakoo, KK | 1 |
| Feng, P | 1 |
| Huang, C | 1 |
| Tsai, CF | 1 |
| Hung, CW | 1 |
| Lirng, JF | 1 |
| Wang, SJ | 1 |
| Fuh, JL | 1 |
| Kim, SY | 1 |
| Lee, DW | 1 |
| -Kim, H | 1 |
| Bang, E | 1 |
| Chae, JH | 1 |
| Choe, BY | 2 |
| Strekalova, T | 1 |
| Costa-Nunes, JP | 1 |
| Veniaminova, E | 1 |
| Kubatiev, A | 1 |
| Lesch, KP | 1 |
| Chekhonin, VP | 1 |
| Evans, MC | 1 |
| Steinbusch, HW | 1 |
| Sui, R | 1 |
| Zhang, Z | 1 |
| Kantorová, E | 1 |
| Poláček, H | 1 |
| Bittšanský, M | 2 |
| Baranovičová, E | 1 |
| Hnilicová, P | 1 |
| Čierny, D | 1 |
| Sivák, Š | 1 |
| Nosáľ, V | 1 |
| Zeleňák, K | 1 |
| Kurča, E | 1 |
| Gao, HX | 1 |
| Campbell, SR | 1 |
| Cui, MH | 1 |
| Zong, P | 1 |
| Hee-Hwang, J | 1 |
| Gulinello, M | 1 |
| Putterman, C | 1 |
| Duan, DM | 1 |
| Tu, Y | 1 |
| Chen, LP | 1 |
| Wu, ZJ | 1 |
| Silver, JM | 1 |
| McAllister, TW | 1 |
| Arciniegas, DB | 1 |
| Bjelland, I | 1 |
| Tell, GS | 1 |
| Vollset, SE | 1 |
| Konstantinova, S | 1 |
| Ueland, PM | 1 |
| Liebes, L | 1 |
| Katz, Y | 1 |
| Liu, S | 1 |
| Mendoza, S | 1 |
| Babb, JS | 1 |
| Klein, RG | 1 |
| Gonen, O | 1 |
| Yang, R | 1 |
| Wu, XP | 1 |
| Bai, XY | 1 |
| Ning, WD | 1 |
| Yang, JL | 1 |
| Xie, ZC | 1 |
| Huang, Y | 1 |
| Chen, W | 1 |
| Li, Y | 2 |
| Wu, X | 1 |
| Shi, X | 1 |
| Geng, D | 1 |
| FORSTER, FM | 1 |
| BORKOWSKI, WJ | 1 |
| McCARTER, RH | 1 |
| Bédard, MJ | 1 |
| Chantal, S | 1 |
| Biedermann, S | 1 |
| Weber-Fahr, W | 1 |
| Zheng, L | 1 |
| Hoyer, C | 1 |
| Vollmayr, B | 1 |
| Gass, P | 1 |
| Ende, G | 1 |
| Sartorius, A | 1 |
| Glenn, MJ | 1 |
| Adams, RS | 1 |
| McClurg, L | 1 |
| Husarova, V | 1 |
| Ondrejka, I | 1 |
| Kerna, V | 1 |
| Dobrota, D | 1 |
| Gruber, S | 1 |
| Frey, R | 1 |
| Mlynárik, V | 1 |
| Stadlbauer, A | 1 |
| Heiden, A | 1 |
| Kasper, S | 1 |
| Kemp, GJ | 1 |
| Moser, E | 1 |
| CIMINO, JP | 1 |
| Johnson, PA | 1 |
| Hurley, RA | 1 |
| Benkelfat, C | 1 |
| Herpertz, SC | 1 |
| Taber, KH | 1 |
| Gonul, AS | 1 |
| Kitis, O | 1 |
| Ozan, E | 1 |
| Akdeniz, F | 1 |
| Eker, C | 1 |
| Eker, OD | 1 |
| Vahip, S | 1 |
| Hong, ST | 1 |
| Choi, CB | 1 |
| Park, C | 1 |
| Hong, KS | 1 |
| Cheong, C | 1 |
| Jeon, YW | 1 |
| Mu, J | 1 |
| Xie, P | 1 |
| Yang, ZS | 1 |
| Yang, DL | 1 |
| Lv, FJ | 1 |
| Luo, TY | 1 |
| Fink, H | 1 |
| Bluth, R | 1 |
| Uebelhack, R | 1 |
| Oelszner, W | 1 |
| Renshaw, PF | 2 |
| Lafer, B | 1 |
| Babb, SM | 1 |
| Fava, M | 1 |
| Stoll, AL | 1 |
| Christensen, JD | 1 |
| Moore, CM | 2 |
| Yurgelun-Todd, DA | 2 |
| Bonello, CM | 1 |
| Pillay, SS | 1 |
| Rothschild, AJ | 1 |
| Nierenberg, AA | 1 |
| Rosenbaum, JF | 1 |
| Cohen, BM | 1 |
| Steingard, RJ | 1 |
| Hennen, J | 1 |
| Moore, JC | 1 |
| Vakili, K | 1 |
| Young, AD | 1 |
| Katic, A | 1 |
| Beardslee, WR | 1 |
| Davis, KL | 1 |
| Hollister, LE | 1 |
| Berger, PA | 1 |
| Tamminga, C | 1 |
| Smith, RC | 1 |
| Chang, S | 1 |
| Haraszti, JS | 1 |
| Davis, JM | 1 |
| Salvadorini, F | 2 |
| Galeone, F | 2 |
| Marescotti, V | 1 |
| Saba, P | 2 |
| Nicotera, M | 1 |
| Ombrato, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Pain Phenotypes in Chronic Pancreatitis and Identification of Clinical Surrogates of Pancreatic Neuropathy[NCT05713344] | 500 participants (Anticipated) | Observational | 2021-08-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for choline and Depression
| Article | Year |
|---|---|
The antidepressant efficacy of the muscarinic antagonist scopolamine: Past findings and future directions.
Topics: Animals; Antidepressive Agents; Choline; Depression; Humans; Muscarinic Antagonists; Scopolamine; Tr | 2020 |
Depression and cognitive complaints following mild traumatic brain injury.
Topics: Antidepressive Agents, Tricyclic; Brain; Brain Injuries; Central Nervous System Stimulants; Choline; | 2009 |
Understanding emotion regulation in borderline personality disorder: contributions of neuroimaging.
Topics: Aspartic Acid; Borderline Personality Disorder; Brain; Brain Mapping; Choline; Compulsive Personalit | 2003 |
6 trials available for choline and Depression
| Article | Year |
|---|---|
Circulating choline pathway nutrients and depression after ischemic stroke.
Topics: Choline; Depression; Humans; Ischemic Stroke; Nutrients; Risk Factors; Stroke | 2022 |
[Study on electroacupuncture treatment of depression by magnetic resonance imaging].
Topics: Adult; Choline; Creatine; Depression; Electroacupuncture; Female; Frontal Lobe; Hippocampus; Humans; | 2009 |
The effect of antidepressant treatment on N-acetyl aspartate levels of medial frontal cortex in drug-free depressed patients.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Choline; Creatine; | 2006 |
Basal ganglia choline levels in depression and response to fluoxetine treatment: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Antidepressive Agents, Second-Generation; Basal Ganglia; Choline; Depression; Female; Fluoxet | 1997 |
Choline chloride in schizophrenia.
Topics: Adult; Brief Psychiatric Rating Scale; Choline; Depression; Drug Evaluation; Humans; Male; Middle Ag | 1979 |
Clinical evaluation of CDP-choline (Nicholin): efficacy As antidepressant treatment.
Topics: Aged; Antidepressive Agents; Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Depres | 1975 |
36 other studies available for choline and Depression
| Article | Year |
|---|---|
Role of citicoline and choline in the treatment of post-stroke depression: an exploratory study.
Topics: Choline; Cytidine Diphosphate Choline; Depression; Humans; Retrospective Studies; Selective Serotoni | 2021 |
Dietary choline is inversely associated with depressive symptoms: A cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2011 to 2018.
Topics: Adult; Choline; Cross-Sectional Studies; Depression; Diet; Humans; Nutrition Surveys | 2022 |
Pain, depression, and poor quality of life in chronic pancreatitis: Relationship with altered brain metabolites.
Topics: Brain; Choline; Depression; Humans; Pain; Pancreatitis, Chronic; Prospective Studies; Quality of Lif | 2022 |
Pupil dilation during negative prediction errors is related to brain choline concentration and depressive symptoms in adolescents.
Topics: Adolescent; Biomarkers; Brain; Choline; Cholinergic Agents; Depression; gamma-Aminobutyric Acid; Glu | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Choline elevation in amygdala region at recovery indicates longer survival without depressive episode: a magnetic resonance spectroscopy study.
Topics: Adult; Amygdala; Antidepressive Agents; Aspartic Acid; Brain; Choline; Depression; Humans; Magnetic | 2021 |
Application of
Topics: Adult; Aspartic Acid; Choline; Creatine; Depression; Female; Frontal Lobe; Humans; Kidney Failure, C | 2020 |
Involvement of muscarinic receptor mechanisms in antidepressant drug action.
Topics: Animals; Antidepressive Agents; Choline; Depression; Humans; Muscarinic Antagonists; Receptors, Musc | 2020 |
Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort.
Topics: Adult; Anxiety; Betaine; Choline; Cohort Studies; Depression; Female; Humans; Personal Satisfaction; | 2017 |
A pilot study of cortical glutathione in youth with depression.
Topics: Adolescent; Anhedonia; Aspartic Acid; Case-Control Studies; Child; Choline; Creatine; Depression; De | 2017 |
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; | 2019 |
Phospholipase D-mTOR signaling is compromised in a rat model of depression.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Brain; Choline; Clomipramine; Depressio | 2013 |
Differences in brain metabolism associated with agitation and depression in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Creatine; Depression; Female; Gyrus Cinguli; Humans | 2013 |
Chronic repetitive transcranial magnetic stimulation enhances GABAergic and cholinergic metabolism in chronic unpredictable mild stress rat model: ¹H-NMR spectroscopy study at 11.7T.
Topics: Animals; Choline; Chronic Disease; Depression; Food Preferences; gamma-Aminobutyric Acid; Hippocampu | 2014 |
Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice.
Topics: Animals; Anxiety; Cholesterol; Choline; Depression; Diet; Female; Inflammation; Mice; Mice, Inbred C | 2016 |
Morphological and Metabolic Alteration of Cerebellum in Patients with Post-Stroke Depression.
Topics: Anisotropy; Case-Control Studies; Cerebellum; Choline; Creatine; Depression; Female; Humans; Magneti | 2016 |
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depre | 2017 |
Depression is an early disease manifestation in lupus-prone MRL/lpr mice.
Topics: Animals; Aspartic Acid; Autoantibodies; Brain; Cardiolipins; Choline; Chromatin; Creatine; Depressio | 2009 |
Choline in anxiety and depression: the Hordaland Health Study.
Topics: Aged; Anxiety; Choline; Cross-Sectional Studies; Depression; Dose-Response Relationship, Drug; Femal | 2009 |
The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Aspartic Acid; Brain; Brain Mapping; Choline; Depression; Fem | 2010 |
[Proton magnetic resonance spectroscopy of the thalamus and hypothalamus in patients with first-episode depression].
Topics: Adolescent; Adult; Case-Control Studies; Choline; Creatine; Depression; Female; Humans; Hypothalamus | 2009 |
Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy.
Topics: Aged; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Case-Control Studie | 2010 |
Depression of the cerebral cortex induced by applications of acetylcholine.
Topics: Acetylcholine; Brain; Cerebral Cortex; Choline; Depression; Depressive Disorder; Humans | 1946 |
Brain magnetic resonance spectroscopy in obsessive-compulsive disorder: the importance of considering subclinical symptoms of anxiety and depression.
Topics: Adult; Anxiety; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Depression; Female; Function | 2011 |
Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression.
Topics: Animals; Choline; Depression; Disease Models, Animal; Electroconvulsive Therapy; gamma-Aminobutyric | 2012 |
Supplemental dietary choline during development exerts antidepressant-like effects in adult female rats.
Topics: Aging; Animals; Antidepressive Agents; Anxiety; Choline; Depression; Dietary Supplements; Female; Ma | 2012 |
Hippocampal neurometabolite changes in depression treatment: a (1)H magnetic resonance spectroscopy study.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Choline; Creatine; Depression; Female; Functional Later | 2012 |
Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by 1H-MRS at 3 Tesla.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depression; Fe | 2003 |
Use of deanol in treatment of chronic fatigue and mild endogenous depression.
Topics: Aminobenzoates; Choline; Deanol; Depression; Depressive Disorder; Fatigue; Humans | 1959 |
Variation of the choline signal intensity in the dorsolateral prefrontal cortex of rats exposed to the forced swimming test as detected by in vivo 1H MR spectroscopy.
Topics: Animals; Aspartic Acid; Choline; Creatine; Depression; Magnetic Resonance Spectroscopy; Male; Prefro | 2007 |
1H magnetic resonance spectroscopy study of thalamus in treatment resistant depressive patients.
Topics: Adult; Aspartic Acid; Choline; Creatine; Depression; Female; Humans; Magnetic Resonance Spectroscopy | 2007 |
Increased choline uptake by erythrocytes of patients with endogenous depression.
Topics: Biological Transport, Active; Choline; Depression; Erythrocytes; Humans; In Vitro Techniques | 1980 |
Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy.
Topics: Adolescent; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cytosol; Depression; Female; Fro | 2000 |
Depression associated with oral choline.
Topics: Administration, Oral; Adult; Choline; Depression; Dyskinesia, Drug-Induced; Female; Humans; Male; Mi | 1976 |
Adrenergic-cholinergic imbalance in affective disorders.
Topics: Animals; Bipolar Disorder; Choline; Depression; Humans; Physostigmine; Receptors, Adrenergic; Recept | 1976 |
[Effect of CDP-choline on GH release in patients with chronic psychopathy].
Topics: Adult; Choline; Chronic Disease; Depression; Female; Growth Hormone; Humans; Male; Mental Disorders; | 1978 |