Page last updated: 2024-10-16

choline and Depression

choline has been researched along with Depression in 45 studies

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Patients with elevated levels of choline and betaine had a lower risk of depression after acute ischemic stroke, suggesting the protective significance of choline pathway nutrients for PSD."9.51Circulating choline pathway nutrients and depression after ischemic stroke. ( Che, B; Du, J; Guo, Y; Ju, Z; Miao, M; Xu, T; Zhang, J; Zhang, Y; Zhong, C; Zhong, X, 2022)
"We have investigated proton magnetic resonance spectra of the basal ganglia in 41 medication-free outpatients with major depression, prior to starting an 8-week standardized trial of open-label fluoxetine, and 22 matched comparison subjects."9.08Basal ganglia choline levels in depression and response to fluoxetine treatment: an in vivo proton magnetic resonance spectroscopy study. ( Babb, SM; Bonello, CM; Christensen, JD; Cohen, BM; Fava, M; Lafer, B; Moore, CM; Nierenberg, AA; Pillay, SS; Renshaw, PF; Rosenbaum, JF; Rothschild, AJ; Stoll, AL; Yurgelun-Todd, DA, 1997)
"This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations."7.85Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017)
"We examined the cross-sectional association between plasma choline concentrations and scores of anxiety and depression symptoms in a general population sample."7.75Choline in anxiety and depression: the Hordaland Health Study. ( Bjelland, I; Konstantinova, S; Tell, GS; Ueland, PM; Vollset, SE, 2009)
"Patients with elevated levels of choline and betaine had a lower risk of depression after acute ischemic stroke, suggesting the protective significance of choline pathway nutrients for PSD."5.51Circulating choline pathway nutrients and depression after ischemic stroke. ( Che, B; Du, J; Guo, Y; Ju, Z; Miao, M; Xu, T; Zhang, J; Zhang, Y; Zhong, C; Zhong, X, 2022)
" The levels of total choline (tCho) and the tCho/N-acetyl aspartate (NAA) ratio were consistently higher in the brains of patients with depression, and that the levels of NAA, glutamate and glutamine (Glx), and gamma-aminobutyric acid (GABA) were lower."4.31Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies. ( Hu, L; Liu, Y; Lv, F; Ma, L; Pu, J; Shen, Y; Shi, Y; Xie, X; Yang, W; Zhang, H, 2023)
" Pain, depression, and emotional components of QOL in patients with CP correlated with N-acetyl aspartate and choline in the left hippocampus and left prefrontal cortex of the brain."4.12Pain, depression, and poor quality of life in chronic pancreatitis: Relationship with altered brain metabolites. ( Bedarkar, AP; Dhagudu, N; Hazarika, D; Jakkampudi, A; M, R; Pandol, SJ; Prasanna, A; Reddy, DN; Sarkar, P; Sarkar, S; Talukdar, R; Unnisa, M, 2022)
" The data with scopolamine are consistent with the adrenergic/cholinergic hypothesis of mania/depression derived from clinical reports originating in the 1970s from Janowsky and colleagues."3.96Involvement of muscarinic receptor mechanisms in antidepressant drug action. ( Brooks, EA; Golani, LK; Martin, AE; Smith, JL; Witkin, JM, 2020)
"This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations."3.85Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017)
" Concentrations of glutamate + glutamin (Glx), cholin (Cho), myoinositol (mIns), N-acetyl aspartate (NAA) expressed as ratio with creatine (Cr) and NAA were correlated with markers of disease activity (RIO score), Multiple Sclerosis Severity Scale (MSSS), Depressive-Severity Status Scale and Simple Numerical Fatigue Scale."3.85Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. ( Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K, 2017)
"Patients with first-episode depression may have myo-inositol and phosphoric acid metabolism disorder in the thalamus and hypothalamus with malfunction of cellular osmotic pressure adjustment mechanism."3.75[Proton magnetic resonance spectroscopy of the thalamus and hypothalamus in patients with first-episode depression]. ( Bai, XY; Ning, WD; Wu, XP; Xie, ZC; Yang, JL; Yang, R, 2009)
"To identify possible alterations in orbitofrontal cortex levels of cytosolic choline in adolescents with and without depression, 22 depressed and 43 control adolescents were recruited."3.70Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy. ( Beardslee, WR; Hennen, J; Katic, A; Moore, CM; Moore, JC; Renshaw, PF; Steingard, RJ; Vakili, K; Young, AD; Yurgelun-Todd, DA, 2000)
" In the study of the dose-response relationship, an L-shaped relationship between dietary choline and depressive symptoms was found."1.72Dietary choline is inversely associated with depressive symptoms: A cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2011 to 2018. ( Kang, X; Li, J; Luo, J; Zhang, D; Zhang, L, 2022)
"Twenty patients had depression recurrence, and 23 patients reached AD discontinuation."1.62Choline elevation in amygdala region at recovery indicates longer survival without depressive episode: a magnetic resonance spectroscopy study. ( Bajs Janović, M; Erdeljić Turk, V; Foro, T; Henigsberg, N; Hrabač, P; Kalember, P; Ozretić, D; Radoš, M; Šarac, H; Savić, A; Šečić, A, 2021)
"Depression is associated with structural and neurochemical changes in limbic structures, including the hippocampus, that control emotion and mood."1.39Phospholipase D-mTOR signaling is compromised in a rat model of depression. ( Feng, P; Huang, C, 2013)
"Agitation and depression are among the commonest behavioural and psychological symptoms exhibited by Alzheimer's disease patients."1.39Differences in brain metabolism associated with agitation and depression in Alzheimer's disease. ( Fuh, JL; Hung, CW; Lirng, JF; Tsai, CF; Wang, SJ, 2013)
"A well-validated animal model of treatment resistant depression (congenital learned helpless rats = cLH) was investigated by hippocampal in vivo ¹H MRS with and without a 1-week course of electroconvulsive shocks (ECS), an animal model of ECT, and compared to wild type (WT) animals, while saline and clomipramine injections served as additional controls."1.38Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression. ( Biedermann, S; Ende, G; Gass, P; Hoyer, C; Sartorius, A; Vollmayr, B; Weber-Fahr, W; Zheng, L, 2012)
"Moreover, depression was significantly correlated with titers of autoantibodies against DNA, NMDA receptors and cardiolipin."1.35Depression is an early disease manifestation in lupus-prone MRL/lpr mice. ( Campbell, SR; Cui, MH; Gao, HX; Gulinello, M; Hee-Hwang, J; Putterman, C; Zong, P, 2009)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19908 (17.78)18.7374
1990's1 (2.22)18.2507
2000's11 (24.44)29.6817
2010's15 (33.33)24.3611
2020's10 (22.22)2.80

Authors

AuthorsStudies
Miao, M1
Du, J1
Che, B1
Guo, Y1
Zhang, J1
Ju, Z1
Xu, T1
Zhong, X1
Zhang, Y1
Zhong, C1
Arcadi, FA1
Corallo, F1
Torrisi, M1
Scarfì, C1
Lo Buono, V1
Formica, C1
Bramanti, P1
Marino, S1
Bonanno, L1
De Cola, MC1
Li, J1
Kang, X1
Zhang, L3
Luo, J1
Zhang, D1
Sarkar, S1
Sarkar, P1
M, R1
Hazarika, D1
Prasanna, A1
Pandol, SJ1
Unnisa, M1
Jakkampudi, A1
Bedarkar, AP1
Dhagudu, N1
Reddy, DN1
Talukdar, R1
Guath, M1
Kleberg, JL1
Weis, J1
Widegren, E1
Frick, M1
Möller, S1
Klevebrant, L1
Karlsson, B1
Fällmar, D1
Mårtensson, J1
Pine, DS1
Brocki, K1
Gingnell, M1
Frick, A1
Xie, X2
Shi, Y2
Ma, L2
Yang, W2
Pu, J2
Shen, Y2
Liu, Y2
Zhang, H2
Lv, F2
Hu, L2
Henigsberg, N1
Savić, A1
Radoš, M2
Šarac, H1
Šečić, A1
Bajs Janović, M1
Foro, T1
Ozretić, D1
Erdeljić Turk, V1
Hrabač, P1
Kalember, P1
Wang, J1
Zhou, T1
Liu, J1
Shangguan, J1
Liu, X1
Li, Z1
Zhou, X1
Ren, Y1
Wang, C1
Witkin, JM1
Smith, JL1
Golani, LK1
Brooks, EA1
Martin, AE1
Drevets, WC1
Bhattacharya, A1
Furey, ML1
van Lee, L1
Quah, PL1
Saw, SM1
Yap, FKP1
Godfrey, KM1
Chong, YS1
Meaney, MJ1
Chen, H1
Chong, MF1
Freed, RD1
Hollenhorst, CN1
Weiduschat, N1
Mao, X1
Kang, G1
Shungu, DC1
Gabbay, V2
Sekar, S1
Grandjean, J1
Garnell, JF1
Willems, R1
Duytschaever, H1
Seramani, S1
Su, H1
Ver Donck, L1
Bhakoo, KK1
Feng, P1
Huang, C1
Tsai, CF1
Hung, CW1
Lirng, JF1
Wang, SJ1
Fuh, JL1
Kim, SY1
Lee, DW1
-Kim, H1
Bang, E1
Chae, JH1
Choe, BY2
Strekalova, T1
Costa-Nunes, JP1
Veniaminova, E1
Kubatiev, A1
Lesch, KP1
Chekhonin, VP1
Evans, MC1
Steinbusch, HW1
Sui, R1
Zhang, Z1
Kantorová, E1
Poláček, H1
Bittšanský, M2
Baranovičová, E1
Hnilicová, P1
Čierny, D1
Sivák, Š1
Nosáľ, V1
Zeleňák, K1
Kurča, E1
Gao, HX1
Campbell, SR1
Cui, MH1
Zong, P1
Hee-Hwang, J1
Gulinello, M1
Putterman, C1
Duan, DM1
Tu, Y1
Chen, LP1
Wu, ZJ1
Silver, JM1
McAllister, TW1
Arciniegas, DB1
Bjelland, I1
Tell, GS1
Vollset, SE1
Konstantinova, S1
Ueland, PM1
Liebes, L1
Katz, Y1
Liu, S1
Mendoza, S1
Babb, JS1
Klein, RG1
Gonen, O1
Yang, R1
Wu, XP1
Bai, XY1
Ning, WD1
Yang, JL1
Xie, ZC1
Huang, Y1
Chen, W1
Li, Y2
Wu, X1
Shi, X1
Geng, D1
FORSTER, FM1
BORKOWSKI, WJ1
McCARTER, RH1
Bédard, MJ1
Chantal, S1
Biedermann, S1
Weber-Fahr, W1
Zheng, L1
Hoyer, C1
Vollmayr, B1
Gass, P1
Ende, G1
Sartorius, A1
Glenn, MJ1
Adams, RS1
McClurg, L1
Husarova, V1
Ondrejka, I1
Kerna, V1
Dobrota, D1
Gruber, S1
Frey, R1
Mlynárik, V1
Stadlbauer, A1
Heiden, A1
Kasper, S1
Kemp, GJ1
Moser, E1
CIMINO, JP1
Johnson, PA1
Hurley, RA1
Benkelfat, C1
Herpertz, SC1
Taber, KH1
Gonul, AS1
Kitis, O1
Ozan, E1
Akdeniz, F1
Eker, C1
Eker, OD1
Vahip, S1
Hong, ST1
Choi, CB1
Park, C1
Hong, KS1
Cheong, C1
Jeon, YW1
Mu, J1
Xie, P1
Yang, ZS1
Yang, DL1
Lv, FJ1
Luo, TY1
Fink, H1
Bluth, R1
Uebelhack, R1
Oelszner, W1
Renshaw, PF2
Lafer, B1
Babb, SM1
Fava, M1
Stoll, AL1
Christensen, JD1
Moore, CM2
Yurgelun-Todd, DA2
Bonello, CM1
Pillay, SS1
Rothschild, AJ1
Nierenberg, AA1
Rosenbaum, JF1
Cohen, BM1
Steingard, RJ1
Hennen, J1
Moore, JC1
Vakili, K1
Young, AD1
Katic, A1
Beardslee, WR1
Davis, KL1
Hollister, LE1
Berger, PA1
Tamminga, C1
Smith, RC1
Chang, S1
Haraszti, JS1
Davis, JM1
Salvadorini, F2
Galeone, F2
Marescotti, V1
Saba, P2
Nicotera, M1
Ombrato, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Pain Phenotypes in Chronic Pancreatitis and Identification of Clinical Surrogates of Pancreatic Neuropathy[NCT05713344]500 participants (Anticipated)Observational2021-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for choline and Depression

ArticleYear
The antidepressant efficacy of the muscarinic antagonist scopolamine: Past findings and future directions.
    Advances in pharmacology (San Diego, Calif.), 2020, Volume: 89

    Topics: Animals; Antidepressive Agents; Choline; Depression; Humans; Muscarinic Antagonists; Scopolamine; Tr

2020
Depression and cognitive complaints following mild traumatic brain injury.
    The American journal of psychiatry, 2009, Volume: 166, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Brain; Brain Injuries; Central Nervous System Stimulants; Choline;

2009
Understanding emotion regulation in borderline personality disorder: contributions of neuroimaging.
    The Journal of neuropsychiatry and clinical neurosciences, 2003,Fall, Volume: 15, Issue:4

    Topics: Aspartic Acid; Borderline Personality Disorder; Brain; Brain Mapping; Choline; Compulsive Personalit

2003

Trials

6 trials available for choline and Depression

ArticleYear
Circulating choline pathway nutrients and depression after ischemic stroke.
    European journal of neurology, 2022, Volume: 29, Issue:2

    Topics: Choline; Depression; Humans; Ischemic Stroke; Nutrients; Risk Factors; Stroke

2022
[Study on electroacupuncture treatment of depression by magnetic resonance imaging].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2009, Volume: 29, Issue:2

    Topics: Adult; Choline; Creatine; Depression; Electroacupuncture; Female; Frontal Lobe; Hippocampus; Humans;

2009
The effect of antidepressant treatment on N-acetyl aspartate levels of medial frontal cortex in drug-free depressed patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:1

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Choline; Creatine;

2006
Basal ganglia choline levels in depression and response to fluoxetine treatment: an in vivo proton magnetic resonance spectroscopy study.
    Biological psychiatry, 1997, Apr-15, Volume: 41, Issue:8

    Topics: Adult; Antidepressive Agents, Second-Generation; Basal Ganglia; Choline; Depression; Female; Fluoxet

1997
Choline chloride in schizophrenia.
    The American journal of psychiatry, 1979, Volume: 136, Issue:12

    Topics: Adult; Brief Psychiatric Rating Scale; Choline; Depression; Drug Evaluation; Humans; Male; Middle Ag

1979
Clinical evaluation of CDP-choline (Nicholin): efficacy As antidepressant treatment.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:3

    Topics: Aged; Antidepressive Agents; Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Depres

1975

Other Studies

36 other studies available for choline and Depression

ArticleYear
Role of citicoline and choline in the treatment of post-stroke depression: an exploratory study.
    The Journal of international medical research, 2021, Volume: 49, Issue:11

    Topics: Choline; Cytidine Diphosphate Choline; Depression; Humans; Retrospective Studies; Selective Serotoni

2021
Dietary choline is inversely associated with depressive symptoms: A cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2011 to 2018.
    Journal of affective disorders, 2022, 03-15, Volume: 301

    Topics: Adult; Choline; Cross-Sectional Studies; Depression; Diet; Humans; Nutrition Surveys

2022
Pain, depression, and poor quality of life in chronic pancreatitis: Relationship with altered brain metabolites.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2022, Volume: 22, Issue:6

    Topics: Brain; Choline; Depression; Humans; Pain; Pancreatitis, Chronic; Prospective Studies; Quality of Lif

2022
Pupil dilation during negative prediction errors is related to brain choline concentration and depressive symptoms in adolescents.
    Behavioural brain research, 2023, 01-05, Volume: 436

    Topics: Adolescent; Biomarkers; Brain; Choline; Cholinergic Agents; Depression; gamma-Aminobutyric Acid; Glu

2023
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
    Journal of affective disorders, 2023, 05-01, Volume: 328

    Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans

2023
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
    Journal of affective disorders, 2023, 05-01, Volume: 328

    Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans

2023
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
    Journal of affective disorders, 2023, 05-01, Volume: 328

    Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans

2023
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
    Journal of affective disorders, 2023, 05-01, Volume: 328

    Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans

2023
Choline elevation in amygdala region at recovery indicates longer survival without depressive episode: a magnetic resonance spectroscopy study.
    Psychopharmacology, 2021, Volume: 238, Issue:5

    Topics: Adult; Amygdala; Antidepressive Agents; Aspartic Acid; Brain; Choline; Depression; Humans; Magnetic

2021
Application of
    BMC nephrology, 2020, 06-15, Volume: 21, Issue:1

    Topics: Adult; Aspartic Acid; Choline; Creatine; Depression; Female; Frontal Lobe; Humans; Kidney Failure, C

2020
Involvement of muscarinic receptor mechanisms in antidepressant drug action.
    Advances in pharmacology (San Diego, Calif.), 2020, Volume: 89

    Topics: Animals; Antidepressive Agents; Choline; Depression; Humans; Muscarinic Antagonists; Receptors, Musc

2020
Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort.
    Depression and anxiety, 2017, Volume: 34, Issue:10

    Topics: Adult; Anxiety; Betaine; Choline; Cohort Studies; Depression; Female; Humans; Personal Satisfaction;

2017
A pilot study of cortical glutathione in youth with depression.
    Psychiatry research. Neuroimaging, 2017, Dec-30, Volume: 270

    Topics: Adolescent; Anhedonia; Aspartic Acid; Case-Control Studies; Child; Choline; Creatine; Depression; De

2017
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists;

2019
Phospholipase D-mTOR signaling is compromised in a rat model of depression.
    Journal of psychiatric research, 2013, Volume: 47, Issue:5

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Brain; Choline; Clomipramine; Depressio

2013
Differences in brain metabolism associated with agitation and depression in Alzheimer's disease.
    East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan, 2013, Volume: 23, Issue:3

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Creatine; Depression; Female; Gyrus Cinguli; Humans

2013
Chronic repetitive transcranial magnetic stimulation enhances GABAergic and cholinergic metabolism in chronic unpredictable mild stress rat model: ¹H-NMR spectroscopy study at 11.7T.
    Neuroscience letters, 2014, Jun-20, Volume: 572

    Topics: Animals; Choline; Chronic Disease; Depression; Food Preferences; gamma-Aminobutyric Acid; Hippocampu

2014
Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice.
    Journal of affective disorders, 2016, May-15, Volume: 196

    Topics: Animals; Anxiety; Cholesterol; Choline; Depression; Diet; Female; Inflammation; Mice; Mice, Inbred C

2016
Morphological and Metabolic Alteration of Cerebellum in Patients with Post-Stroke Depression.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:3-4

    Topics: Anisotropy; Case-Control Studies; Cerebellum; Choline; Creatine; Depression; Female; Humans; Magneti

2016
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
    Neurological research, 2017, Volume: 39, Issue:4

    Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depre

2017
Depression is an early disease manifestation in lupus-prone MRL/lpr mice.
    Journal of neuroimmunology, 2009, Feb-15, Volume: 207, Issue:1-2

    Topics: Animals; Aspartic Acid; Autoantibodies; Brain; Cardiolipins; Choline; Chromatin; Creatine; Depressio

2009
Choline in anxiety and depression: the Hordaland Health Study.
    The American journal of clinical nutrition, 2009, Volume: 90, Issue:4

    Topics: Aged; Anxiety; Choline; Cross-Sectional Studies; Depression; Dose-Response Relationship, Drug; Femal

2009
The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Feb-01, Volume: 34, Issue:1

    Topics: 3-Hydroxyanthranilic Acid; Adolescent; Aspartic Acid; Brain; Brain Mapping; Choline; Depression; Fem

2010
[Proton magnetic resonance spectroscopy of the thalamus and hypothalamus in patients with first-episode depression].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:12

    Topics: Adolescent; Adult; Case-Control Studies; Choline; Creatine; Depression; Female; Humans; Hypothalamus

2009
Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy.
    Psychiatry research, 2010, Apr-30, Volume: 182, Issue:1

    Topics: Aged; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Case-Control Studie

2010
Depression of the cerebral cortex induced by applications of acetylcholine.
    Federation proceedings, 1946, Volume: 5, Issue:1

    Topics: Acetylcholine; Brain; Cerebral Cortex; Choline; Depression; Depressive Disorder; Humans

1946
Brain magnetic resonance spectroscopy in obsessive-compulsive disorder: the importance of considering subclinical symptoms of anxiety and depression.
    Psychiatry research, 2011, Apr-30, Volume: 192, Issue:1

    Topics: Adult; Anxiety; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Depression; Female; Function

2011
Increase of hippocampal glutamate after electroconvulsive treatment: a quantitative proton MR spectroscopy study at 9.4 T in an animal model of depression.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2012, Volume: 13, Issue:6

    Topics: Animals; Choline; Depression; Disease Models, Animal; Electroconvulsive Therapy; gamma-Aminobutyric

2012
Supplemental dietary choline during development exerts antidepressant-like effects in adult female rats.
    Brain research, 2012, Mar-14, Volume: 1443

    Topics: Aging; Animals; Antidepressive Agents; Anxiety; Choline; Depression; Dietary Supplements; Female; Ma

2012
Hippocampal neurometabolite changes in depression treatment: a (1)H magnetic resonance spectroscopy study.
    Psychiatry research, 2012, Mar-31, Volume: 201, Issue:3

    Topics: Adult; Antidepressive Agents; Aspartic Acid; Choline; Creatine; Depression; Female; Functional Later

2012
Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by 1H-MRS at 3 Tesla.
    Investigative radiology, 2003, Volume: 38, Issue:7

    Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depression; Fe

2003
Use of deanol in treatment of chronic fatigue and mild endogenous depression.
    The Journal of the American Osteopathic Association, 1959, Volume: 58, Issue:9

    Topics: Aminobenzoates; Choline; Deanol; Depression; Depressive Disorder; Fatigue; Humans

1959
Variation of the choline signal intensity in the dorsolateral prefrontal cortex of rats exposed to the forced swimming test as detected by in vivo 1H MR spectroscopy.
    Journal of neuroscience methods, 2007, Sep-15, Volume: 165, Issue:1

    Topics: Animals; Aspartic Acid; Choline; Creatine; Depression; Magnetic Resonance Spectroscopy; Male; Prefro

2007
1H magnetic resonance spectroscopy study of thalamus in treatment resistant depressive patients.
    Neuroscience letters, 2007, Sep-20, Volume: 425, Issue:1

    Topics: Adult; Aspartic Acid; Choline; Creatine; Depression; Female; Humans; Magnetic Resonance Spectroscopy

2007
Increased choline uptake by erythrocytes of patients with endogenous depression.
    Psychopharmacology bulletin, 1980, Volume: 16, Issue:3

    Topics: Biological Transport, Active; Choline; Depression; Erythrocytes; Humans; In Vitro Techniques

1980
Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy.
    Biological psychiatry, 2000, Dec-01, Volume: 48, Issue:11

    Topics: Adolescent; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cytosol; Depression; Female; Fro

2000
Depression associated with oral choline.
    Lancet (London, England), 1976, Oct-23, Volume: 2, Issue:7991

    Topics: Administration, Oral; Adult; Choline; Depression; Dyskinesia, Drug-Induced; Female; Humans; Male; Mi

1976
Adrenergic-cholinergic imbalance in affective disorders.
    Lancet (London, England), 1976, Dec-18, Volume: 2, Issue:7999

    Topics: Animals; Bipolar Disorder; Choline; Depression; Humans; Physostigmine; Receptors, Adrenergic; Recept

1976
[Effect of CDP-choline on GH release in patients with chronic psychopathy].
    La Clinica terapeutica, 1978, Jun-30, Volume: 85, Issue:6

    Topics: Adult; Choline; Chronic Disease; Depression; Female; Growth Hormone; Humans; Male; Mental Disorders;

1978