Page last updated: 2024-08-23

s-adenosylmethionine and Depression

s-adenosylmethionine has been researched along with Depression in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (20.00)	18.7374
1990's	7 (11.67)	18.2507
2000's	23 (38.33)	29.6817
2010's	11 (18.33)	24.3611
2020's	7 (11.67)	2.80

Authors

Authors	Studies
Arnold, M; Dehkordi, SM; Dunlop, BW; Kaddurah-Daouk, R; Kastenmüller, G; Krishnan, RR; Milaneschi, Y; Penninx, BWJH; Rush, AJ	1
Ahmed, AT; Arnold, M; Baillie, RA; Bhattacharyya, S; Craighead, WE; Dunlop, BW; Frye, MA; Han, X; John-Williams, LS; Kaddurah-Daouk, R; Krishnan, R; Louie, G; MahmoudianDehkordi, S; McDonald, W; Moseley, MA; Riva-Posse, P; Rush, AJ; Skime, MK; Thompson, JW; Weinshilboum, RM	1
Chen, S; Dai, W; Gao, P; Hu, C; Jia, Z; Kong, H; Wei, C; Wu, Y; Xu, G	1
Cassol, E; Gabuzda, D; Kirk, GD; Mehta, SH; Misra, V; Morgello, S	1
Amjad, S; Chalmers, RA; Goodwin, CS; Jones, MG	1
Daglia, M; Di Minno, A; Khan, A; Rengasamy, KRR; Sacchi, R; Ullah, H	1
Baldi, A; Cioffi, V; Daglia, M; Di Minno, A; El-Seedi, HR; Esposito, C; Greco, A; Khalifa, SAM; Sacchi, R; Santonastaso, S; Sperandeo, R; Ullah, H	1
Becker, M; Gorobets, D; Ornoy, A; Pinhasov, A; Shmerkin, E; Weinstein-Fudim, L	1
Adams, L; Berk, M; Bousman, C; Byrne, GJ; Chamoli, S; Cribb, L; MacDonald, P; Menon, R; Mischoulon, D; Murphy, J; Nazareth, S; Ng, CH; Oliver, G; Sarris, J; Savage, K; Stough, C	1
Brasesco, PC; Castagnaro, R; Fioravanti, P; Guida, V; Massardo, I; Montarsolo, P; Montisci, R; Pedemonte, A; Picciotto, R; Picco, P; Saccarello, A; Schiavetti, I; Vanelli, A	1
Awwad, HM; Eskelund, AR; Geisel, J; Obeid, R; Tillmann, S; Treccani, G; Wegener, G	1
Abeysundera, H; Gill, R	1
Geisel, J; Happ, DF; Mikkelsen, PF; Obeid, R; Tillmann, S; Wegener, G	1
Bottiglieri, T	2
Deligiannidis, KM; Freeman, MP	1
Lopresti, AL	1
Bhatia, P; Singh, N	1
Karas Kuželički, N	1
Amari, E; Dougall, D; Galizia, I; Jones, TN; Lam, RW; Macritchie, K; Massei, GJ; Oldani, L; Yatham, LN; Young, AH	1
Adler, S; Kotler, M; Lachman, H; Maayan, R; Ratner, Y; Ritsner, MS; Strous, RD; Weizman, A	1
Miller, AL	1
Kavanagh, DJ; Sarris, J; Schoendorfer, N	1
Hanson, EA	1
Mischoulon, D	1
Keller, L	1
Fava, M; Mischoulon, D	1
Anderer, P; Assandri, A; di Padova, C; Lindeck-Pozza, E; Linzmayer, L; Saletu, B; Saletu-Zyhlarz, GM; Semlitsch, HV	1
Young, SN	1
Girard, C; Jui, D; Katz, DL; Sabina, A; Williams, AL	1
Alcaraz, P; Bacci Ballerini, F; Hernández Reyes, N; López Anguera, A	1
Charlton, CG	1
Cowley, G; Underwood, A	1
Gorman, C	1
Cerrato, PL; Rowell, N	1
Chavez, M	1
Ramos, L	1
Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK	1
Lee, NP; Shu, L	1
Bottiglieri, T; Brown, R; Di Rocco, A; Rogers, JD; Werner, P	1
Boorstin, J	1
Benelli, A; Bertolini, A; Filaferro, M; Genedani, S; Saltini, S	1
Bellido, I; Gomez-Luque, A; Ortiz, P; Plaza, A; Rius, F; Sanchez de la Cuesta, F	1
Guazzelli, M; Maggini, C	1
Agnoli, A; Andreoli, VM; Casacchia, M; Fazio, C; Maffei, F	1
Andreoli, VM; Maffei, F; Tonon, GC	1
Agnoli, A; Andreoli, V; Bonamini, F; Carolei, A; Casacchia, M; Cerbo, R; De Carolis, V; Fazio, C; Pastorino, P; Ruggieri, S	1
Agnoli, A; Andreoli, V; Casacchia, M; Cerbo, R	1
Agnoli, A; Carolei, A; Mantero, M; Pastorino, P	1
Otero Losada, ME; Rubio, MC	1
Reynolds, EH	1
Ohno, M; Ueki, S; Yamamoto, T; Yatsugi, S	1
di Padova, C	1
König, B	1
Axelrod, J; Saavedra, JM; Wyatt, RJ	1
Agnoli, A; Andreoli, V; Casacchia, M; Cerbo, R; Fazio, C	1

Reviews

17 review(s) available for s-adenosylmethionine and Depression

Article	Year
Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression. Journal of affective disorders, 2022, 06-15, Volume: 307 Topics: Carnitine; Causality; Depression; Genomics; Humans	2022
The Efficacy of S-Adenosyl Methionine and Probiotic Supplementation on Depression: A Synergistic Approach. Nutrients, 2022, Jul-01, Volume: 14, Issue:13 Topics: Depression; Dietary Supplements; Dysbiosis; Humans; Probiotics; S-Adenosylmethionine	2022
Folate, vitamin B₁₂, and S-adenosylmethionine. The Psychiatric clinics of North America, 2013, Volume: 36, Issue:1 Topics: Clinical Trials as Topic; Dementia; Depression; Folic Acid; Humans; S-Adenosylmethionine; Vitamin B 12	2013
Complementary and alternative medicine therapies for perinatal depression. Best practice & research. Clinical obstetrics & gynaecology, 2014, Volume: 28, Issue:1 Topics: Acupuncture Therapy; Complementary Therapies; Depression; Depression, Postpartum; Dietary Supplements; Exercise; Fatty Acids, Omega-3; Female; Folic Acid; Humans; Hypericum; Massage; Mothers; Peripartum Period; Phototherapy; Pregnancy; S-Adenosylmethionine	2014
A review of nutrient treatments for paediatric depression. Journal of affective disorders, 2015, Aug-01, Volume: 181 Topics: Adolescent; Antidepressive Agents; Child; Depression; Fatty Acids, Omega-3; Humans; S-Adenosylmethionine; Vitamins	2015
Homocysteine excess: delineating the possible mechanism of neurotoxicity and depression. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:6 Topics: Cysteine; Depression; Homocysteine; Humans; Hyperhomocysteinemia; Neurotoxicity Syndromes; S-Adenosylmethionine	2015
S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders. Drug development research, 2016, Volume: 77, Issue:7 Topics: Animals; Depression; DNA Methylation; Epigenesis, Genetic; Homocysteine; Humans; Mental Disorders; Methylation; S-Adenosylmethionine; Time Factors	2016
S-adenosyl methionine (SAMe) for depression in adults. The Cochrane database of systematic reviews, 2016, Oct-10, Volume: 10 Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Depression; Humans; Imipramine; Middle Aged; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors	2016
The methylation, neurotransmitter, and antioxidant connections between folate and depression. Alternative medicine review : a journal of clinical therapeutic, 2008, Volume: 13, Issue:3 Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates	2008
Major depressive disorder and nutritional medicine: a review of monotherapies and adjuvant treatments. Nutrition reviews, 2009, Volume: 67, Issue:3 Topics: Amino Acids; Antidepressive Agents; Chemotherapy, Adjuvant; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Folic Acid; Humans; Nutritional Physiological Phenomena; Nutritional Status; S-Adenosylmethionine; Tryptophan	2009
SAMe: uses will evolve with more research. Advance for nurse practitioners, 2001, Volume: 9, Issue:6 Topics: Antidepressive Agents; Depression; Humans; Nonprescription Drugs; Nurse Practitioners; Patient Education as Topic; Primary Health Care; S-Adenosylmethionine	2001
S-Adenosyl-L-methionine (SAMe): from the bench to the bedside--molecular basis of a pleiotrophic molecule. The American journal of clinical nutrition, 2002, Volume: 76, Issue:5 Topics: Animals; Depression; Diffusion of Innovation; Humans; Liver Diseases; Methylation; Nervous System Diseases; Osteoarthritis; S-Adenosylmethionine; Tissue Distribution	2002
Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. The American journal of clinical nutrition, 2002, Volume: 76, Issue:5 Topics: Antidepressive Agents; Depression; Humans; S-Adenosylmethionine	2002
S-adenosylmethionine (SAMe) as treatment for depression: a systematic review. Clinical and investigative medicine. Medecine clinique et experimentale, 2005, Volume: 28, Issue:3 Topics: Clinical Trials as Topic; Databases, Bibliographic; Depression; Humans; S-Adenosylmethionine; Time Factors; Treatment Outcome	2005
SAMe: S-Adenosylmethionine. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Jan-15, Volume: 57, Issue:2 Topics: Arthritis; Depression; Humans; Liver Diseases; S-Adenosylmethionine	2000
[The importance of methylation reactions in the biochemistry of catecholaminergic and serotoninergic neurons]. Medicina, 1991, Volume: 51, Issue:3 Topics: Animals; Brain; Depression; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Methylation; Rats; S-Adenosylmethionine; Serotonin; Sodium	1991
Interictal psychiatric disorders. Neurochemical aspects. Advances in neurology, 1991, Volume: 55 Topics: Anticonvulsants; Biogenic Amines; Depression; Epilepsy; Folic Acid; gamma-Aminobutyric Acid; Humans; Mental Disorders; S-Adenosylmethionine	1991

Trials

15 trial(s) available for s-adenosylmethionine and Depression

Article	Year
Efficacy of a food supplement based on S-adenosyl methionine and probiotic strains in subjects with subthreshold depression and mild-to-moderate depression: A monocentric, randomized, cross-over, double-blind, placebo-controlled clinical trial. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156 Topics: Depression; Depressive Disorder, Major; Dietary Supplements; Double-Blind Method; Humans; Probiotics; Quality of Life; S-Adenosylmethionine	2022
S-Adenosylmethionine (SAMe) monotherapy for depression: an 8-week double-blind, randomised, controlled trial. Psychopharmacology, 2020, Volume: 237, Issue:1 Topics: Adult; Antidepressive Agents; Australia; Depression; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; S-Adenosylmethionine; Treatment Outcome	2020
Oral Administration of S-Adenosylmethionine (SAMe) and Lactobacillus Plantarum HEAL9 Improves the Mild-To-Moderate Symptoms of Depression: A Randomized, Double-Blind, Placebo-Controlled Study. The primary care companion for CNS disorders, 2020, Jun-25, Volume: 22, Issue:4 Topics: Adolescent; Adult; Depression; Depressive Disorder; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Humans; Lactobacillus plantarum; Male; Middle Aged; Outcome Assessment, Health Care; Probiotics; S-Adenosylmethionine; Severity of Illness Index; Young Adult	2020
Improvement of aggressive behavior and quality of life impairment following S-adenosyl-methionine (SAM-e) augmentation in schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:1 Topics: Adolescent; Adult; Aged; Aggression; Cognition; Depression; Dietary Supplements; Dopamine; Female; Genotype; Humans; Male; Middle Aged; Neuropsychological Tests; Norepinephrine; Psychiatric Status Rating Scales; Psychomotor Performance; Quality of Life; S-Adenosylmethionine; Schizophrenia; Schizophrenic Psychology; Sex Characteristics; Treatment Outcome; Young Adult	2009
Pharmacodynamic studies on the central mode of action of S-adenosyl-L-methionine (SAMe) infusions in elderly subjects, utilizing EEG mapping and psychometry. Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:12 Topics: Aged; Antidepressive Agents; Brain; Cross-Over Studies; Depression; Electroencephalography; Female; Humans; Male; Middle Aged; Multivariate Analysis; Psychometrics; S-Adenosylmethionine	2002
[Treatment of postconcussion syndrome with S-adenosylmethionine]. Medicina clinica, 1983, Volume: 80, Issue:4 Topics: Adolescent; Adult; Brain Concussion; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Random Allocation; S-Adenosylmethionine; Syndrome; Vertigo	1983
Homocysteine, folate, methylation, and monoamine metabolism in depression. Journal of neurology, neurosurgery, and psychiatry, 2000, Volume: 69, Issue:2 Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12	2000
S-Adenosyl-Methionine improves depression in patients with Parkinson's disease in an open-label clinical trial. Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:6 Topics: Aged; Antidepressive Agents; Depression; Female; Humans; Male; Middle Aged; Parkinson Disease; Patient Dropouts; Pilot Projects; Psychiatric Status Rating Scales; S-Adenosylmethionine; Treatment Outcome	2000
Results and possible developments of the clinical use of S-adenosyl-L-methionine (SAMe) in psychiatry. Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18 Topics: Clinical Trials as Topic; Depression; Double-Blind Method; Humans; MMPI; Psychiatric Status Rating Scales; S-Adenosylmethionine; Schizophrenia	1978
[Neuropsychiatric disorders and transmethylation: therapeutic effects of S-adenosyl-L-methionine]. La Clinica terapeutica, 1975, Dec-31, Volume: 75, Issue:6 Topics: Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Methylation; S-Adenosylmethionine	1975
Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms. Journal of psychiatric research, 1976, Volume: 13, Issue:1 Topics: Adjustment Disorders; Adult; Aged; Anxiety; Attitude; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Drug Evaluation; Female; Humans; Hypochondriasis; Male; Middle Aged; Placebos; Psychomotor Disorders; Psychophysiologic Disorders; S-Adenosylmethionine; Suicide Prevention; Time Factors	1976
[Controlled double-blind study (SAMe-imipramine) in depressive syndromes]. Minerva medica, 1975, Nov-17, Volume: 66, Issue:78 Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Imipramine; Injections, Intramuscular; Male; Middle Aged; S-Adenosylmethionine; Suicide	1975
S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. The American journal of medicine, 1987, Nov-20, Volume: 83, Issue:5A Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Clinical Trials as Topic; Depression; Double-Blind Method; Humans; Osteoarthritis; Proteoglycans; S-Adenosylmethionine	1987
A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. The American journal of medicine, 1987, Nov-20, Volume: 83, Issue:5A Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Depression; Female; Humans; Longitudinal Studies; Male; Middle Aged; Osteoarthritis; Psychological Tests; S-Adenosylmethionine	1987
[Therapeutic effects and mechanism of action of S-adenosyl-L-methionine (SAM) in depressive syndromes]. Minerva medica, 1973, Apr-30, Volume: 64, Issue:29 Topics: Adjustment Disorders; Adrenal Glands; Adult; Aged; Animals; Bipolar Disorder; Brain; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Female; Humans; Liver; Lung; Male; Middle Aged; Myocardium; S-Adenosylmethionine	1973

Other Studies

28 other study(ies) available for s-adenosylmethionine and Depression

Article	Year
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression. Translational psychiatry, 2021, 03-02, Volume: 11, Issue:1 Topics: Amines; Antidepressive Agents; Carnitine; Citalopram; Depression; Depressive Disorder, Major; Humans; Lipids; Selective Serotonin Reuptake Inhibitors	2021
Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2014, Volume: 89 Topics: Allium; Animals; Antidepressive Agents; Carnitine; Chromatography, High Pressure Liquid; Depression; Disease Models, Animal; Lipids; Male; Mass Spectrometry; Medicine, Chinese Traditional; Metabolome; Principal Component Analysis; Rats; Rats, Wistar	2014
Altered Monoamine and Acylcarnitine Metabolites in HIV-Positive and HIV-Negative Subjects With Depression. Journal of acquired immune deficiency syndromes (1999), 2015, May-01, Volume: 69, Issue:1 Topics: Adult; Biogenic Monoamines; Carnitine; Cohort Studies; Depression; Female; HIV Infections; Humans; Male; Metabolome; Middle Aged; Plasma	2015
Plasma and urinary carnitine and acylcarnitines in chronic fatigue syndrome. Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 360, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Carnitine; Case-Control Studies; Depression; Fatigue Syndrome, Chronic; Female; Humans; Male; Middle Aged; Muscle Fatigue	2005
Prenatal SAMe Treatment Changes via Epigenetic Mechanism/s USVs in Young Mice and Hippocampal Monoamines Turnover at Adulthood in a Mouse Model of Social Hierarchy and Depression. International journal of molecular sciences, 2023, Jun-27, Volume: 24, Issue:13 Topics: Animals; Depression; Dopamine; Female; Hierarchy, Social; Hippocampus; Male; Mice; Norepinephrine; Pregnancy; S-Adenosylmethionine; Vocalization, Animal	2023
Probiotics Affect One-Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression. Molecular nutrition & food research, 2018, Volume: 62, Issue:7 Topics: Animals; Antidepressive Agents; Behavior, Animal; Bifidobacterium longum; Biomarkers; Depression; Dopamine; Dopamine Antagonists; Freeze Drying; Hippocampus; Homocysteine; Lactobacillus helveticus; Liver; Male; Methylation; Neurons; Norepinephrine; Prefrontal Cortex; Probiotics; Random Allocation; Rats, Mutant Strains; S-Adenosylmethionine	2018
Possible SAMe-induced mania. BMJ case reports, 2018, Jun-27, Volume: 2018 Topics: Adult; Bipolar Disorder; Citalopram; Depression; Drug Therapy, Combination; Female; Hallucinations; Humans; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors	2018
Behavioral and metabolic effects of S-adenosylmethionine and imipramine in the Flinders Sensitive Line rat model of depression. Behavioural brain research, 2019, 05-17, Volume: 364 Topics: Animals; Antidepressive Agents; Brain; Cognition; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; Hippocampus; Imipramine; Male; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Serotonin; Spatial Memory	2019
Can adenosine substitute for SAM-e as an adjunct in the treatment of depression? Medical hypotheses, 2009, Volume: 73, Issue:5 Topics: Adenosine; Antidepressive Agents; Depression; Humans; Models, Theoretical; S-Adenosylmethionine	2009
Update and critique of natural remedies as antidepressant treatments. Obstetrics and gynecology clinics of North America, 2009, Volume: 36, Issue:4 Topics: Antidepressive Agents; Complementary Therapies; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Humans; Hypericum; Phytotherapy; S-Adenosylmethionine	2009
Are SAMe and 5-HTP safe and effective treatments for depression? Journal of psychiatry & neuroscience : JPN, 2003, Volume: 28, Issue:6 Topics: 5-Hydroxytryptophan; Anti-Inflammatory Agents; Antidepressive Agents; Depression; Humans; Male; Middle Aged; S-Adenosylmethionine	2003
SAMe reconsidered. The Harvard mental health letter, 2004, Volume: 20, Issue:7 Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Humans; S-Adenosylmethionine	2004
Update on dietary supplements for depression. Harvard women's health watch, 2004, Volume: 11, Issue:7 Topics: Depression; Dietary Supplements; Fatty Acids, Omega-3; Folic Acid; Humans; Hypericum; Phytotherapy; S-Adenosylmethionine	2004
Depletion of nigrostriatal and forebrain tyrosine hydroxylase by S-adenosylmethionine: a model that may explain the occurrence of depression in Parkinson's disease. Life sciences, 1997, Volume: 61, Issue:5 Topics: Animals; Corpus Striatum; Depression; Fluorescent Antibody Technique, Indirect; Male; Parkinson Disease; Prosencephalon; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Substantia Nigra; Tyrosine 3-Monooxygenase	1997
What is SAMe? S-Adenosylmethionine. Newsweek, 1999, Jul-05, Volume: 134, Issue:1 Topics: Arthritis; Chronic Disease; Depression; Dietary Supplements; Health Education; Humans; Liver Diseases; Methylation; Nonprescription Drugs; S-Adenosylmethionine; United States	1999
Is SAMe for real? Time, 1999, Aug-16, Volume: 154, Issue:7 Topics: Arthritis; Complementary Therapies; Depression; Dietary Supplements; Drug Costs; Health Education; Humans; S-Adenosylmethionine; United States	1999
SAMe for depression. The Medical letter on drugs and therapeutics, 1999, Nov-05, Volume: 41, Issue:1065 Topics: Administration, Oral; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Clinical Trials as Topic; Depression; Desipramine; Diarrhea; Dietary Supplements; Drug Stability; Fees, Pharmaceutical; Headache; Humans; Nausea; S-Adenosylmethionine; Vomiting	1999
SAMe: a dietary remedy for mind and body? RN, 1999, Volume: 62, Issue:12 Topics: Depression; Dietary Supplements; Food, Organic; Humans; Osteoarthritis; S-Adenosylmethionine; Treatment Outcome	1999
SAMe as a supplement: can it really help treat depression and arthritis? Journal of the American Dietetic Association, 2000, Volume: 100, Issue:4 Topics: Depression; Dietary Supplements; Humans; Osteoarthritis; S-Adenosylmethionine	2000
SAMe targets consumers via the Web. The Western journal of medicine, 2000, Volume: 173, Issue:4 Topics: Advertising; Antidepressive Agents; Depression; Dietary Supplements; Humans; Internet; S-Adenosylmethionine	2000
SAMe for depression. The Harvard mental health letter, 2001, Volume: 17, Issue:7 Topics: Depression; Humans; S-Adenosylmethionine	2001
Users say SAM-e is a wonder drug ... are they high? Fortune, 2000, Nov-13, Volume: 142, Issue:11 Topics: Depression; Humans; Liver Diseases; Osteoarthritis; S-Adenosylmethionine; United States	2000
Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression. Neuroreport, 2001, Dec-21, Volume: 12, Issue:18 Topics: Animals; Antidepressive Agents; Biogenic Polyamines; Brain Chemistry; Chronic Disease; Depression; Dietary Sucrose; Disease Models, Animal; Eating; Female; Hippocampus; Nucleus Accumbens; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Stress, Physiological	2001
S-adenosyl-L-methionine prevents 5-HT(1A) receptors up-regulation induced by acute imipramine in the frontal cortex of the rat. Neuroscience letters, 2002, Mar-15, Volume: 321, Issue:1-2 Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Drug Interactions; Frontal Lobe; Imipramine; Male; Motor Activity; Neural Inhibition; Neurons; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; S-Adenosylmethionine; Serotonin; Stress, Psychological; Synaptic Transmission; Up-Regulation	2002
A polygraph evaluation of the effects of S-adenosyl-L-methionine (SAMe) on all-night sleep. Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18 Topics: Adult; Aged; Depression; Electroencephalography; Electromyography; Electrooculography; Humans; Male; S-Adenosylmethionine; Sleep; Sleep, REM	1978
S-adenosyl-L-methionine (SAMe) blood levels in schizophrenia and depression. Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18 Topics: Adult; Depression; Humans; Middle Aged; S-Adenosylmethionine; Schizophrenia	1978
Inhibition of mouse-killing behavior by S-adenosyl-L-methionine in midbrain raphe-lesioned and olfactory-bulbectomized rats. Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:2 Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mesencephalon; Mice; Olfactory Bulb; Raphe Nuclei; Rats; Rats, Inbred Strains; S-Adenosylmethionine	1989
A dimethyltryptamine-forming enzyme in human blood. The American journal of psychiatry, 1973, Volume: 130, Issue:7 Topics: Adolescent; Adult; Alcoholism; Blood Platelets; Blood Proteins; Carbon Isotopes; Depression; Erythrocytes; Female; Hallucinogens; Humans; Male; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Psychotic Disorders; Renal Dialysis; S-Adenosylmethionine; Schizophrenia; Tryptamines	1973