| Assay ID | Title | Year | Journal | Article |
|---|
| AID238970 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D2L receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID248805 | Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID62008 | Compound was evaluated for binding affinity against Dopamine receptor D2 subtype from primate | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID749538 | Displacement of [125I]ABN from human dopamine D4.4 receptor expressed in HEK293 cells after 60 mins by gamma counting analysis | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID248745 | Antagonist activity against 100 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID297343 | Selectivity for human dopamine D3 receptor over human 5HT2A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID64186 | Compound was evaluated for binding affinity against human Dopamine receptor D5 transfected in CHO cell membranes | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID238921 | Inhibition of [125I]IABN binding to rat Dopamine D2L receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID243003 | Ratio of binding affinity at dopamine D2L over D3 receptors | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID1232330 | Selectivity index, ratio of Ki for human dopamine D2 receptor to KI for human dopamine D3 receptor | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID246572 | Inhibition of quinpirole stimulation of mitogenesis at human dopamine D2 receptors expressed in Chinese hamster ovary cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID297333 | Selectivity for human dopamine D3 receptor over human dopamine D2 receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID243111 | Relative binding affinity for human dopamine D2 and D3 receptors | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID63541 | Compound was evaluated for binding affinity against human Dopamine receptor D4 transfected in CHO cell membranes | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID238906 | Inhibition of [125I]IABN binding to rat Dopamine D3 receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID238947 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID256759 | Intrinsic activity against dopamine receptor D3 by Eu-GTP binding assay | 2005 | Journal of medicinal chemistry, Dec-15, Volume: 48, Issue:25
| First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure. |
| AID249434 | Relative inhibition of quinpirole stimulation at human dopamine D2 and D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID21869 | Calculated partition coefficient (clogD) | 2003 | Bioorganic & medicinal chemistry letters, Jul-07, Volume: 13, Issue:13
| N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. |
| AID63638 | Ratio of binding affinities of D2 receptor to D3 receptor | 2003 | Bioorganic & medicinal chemistry letters, Jul-07, Volume: 13, Issue:13
| N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. |
| AID65603 | Binding affinity at dopamine receptor D3 on Sf9 cells by [125I]IABN displacement. | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. |
| AID297340 | Binding affinity to human 5HT2A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID63349 | Compound was evaluated for binding affinity against Dopamine receptor D1 transfected in CHO cell membranes | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID45592 | Compound was tested for stimulation of mitogenesis in CHO.hD3 cells in a dose dependent manner | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID749537 | Selectivity ratio of Ki for human dopamine D2L receptor to Ki for human dopamine D3 receptor | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID297336 | Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assay | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID246573 | Inhibition of quinpirole stimulation of mitogenesis at human dopamine D3 receptors expressed in Chinese hamster ovary cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID688180 | Selectivity ratio of dopamine D1 like receptor to dopamine D3 receptor | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| High-affinity and selective dopamine D₃ receptor full agonists. |
| AID239022 | Inhibition of [3H]YM-09151-2 binding to primate Dopamine D2L receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID256758 | Displacement of [3H]spiroperidol from cloned human dopamine receptor D3 in CHO cell membrane | 2005 | Journal of medicinal chemistry, Dec-15, Volume: 48, Issue:25
| First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure. |
| AID1232331 | Selectivity index, ratio of Ki for human dopamine D4 receptor to KI for human dopamine D3 receptor | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID238948 | Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID239001 | Inhibition of [3H]YM-09151-2 binding to primate Dopamine D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID249049 | Compound tested for locomotor activity in male Swiss-Webster mice (n=8) | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID597447 | Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma counting | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID248806 | Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID297342 | Selectivity for human dopamine D3 receptor over human 5HT1A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID229809 | Relative binding to Dopamine D2 long and D3 receptors (Ratio of Ki) | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. |
| AID249398 | Dopamine receptor D2/D3 selectivity ratio from in vitro functional assays | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID65129 | Compound was evaluated for binding affinity against human Dopamine receptor D3 transfected in CHO cell membranes to stimulate [3H]thymidine uptake | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID238949 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D4 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID1232329 | Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cells | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID297331 | Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID5254 | Compound was evaluated for binding affinity against 5-hydroxytryptamine 2 receptor from rat | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID749539 | Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma counting analysis | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID37464 | Compound was evaluated for binding affinity against Alpha-1 adrenergic receptor from rat | 1998 | Bioorganic & medicinal chemistry letters, Oct-06, Volume: 8, Issue:19
| NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists. |
| AID65612 | Binding affinity towards rat Dopamine receptor D3 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]IABN as radioligand | 2003 | Bioorganic & medicinal chemistry letters, Jul-07, Volume: 13, Issue:13
| N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. |
| AID297344 | Selectivity for human dopamine D3 receptor over human 5HT2C receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID297335 | Antagonist activity at human dopamine D2 receptor expressed in HEK293 cells by mitogenesis assay | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID297332 | Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cells | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID65085 | Binding affinity at dopamine receptor D2 on Sf9 cells by [125I]IABN displacement. | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. |
| AID65246 | Binding affinity towards rat Dopamine receptor D2 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]IABN as radioligand | 2003 | Bioorganic & medicinal chemistry letters, Jul-07, Volume: 13, Issue:13
| N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. |
| AID297341 | Binding affinity to human 5HT2C receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID238971 | Inhibition of [125I]IABN binding to human Dopamine D2L receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID1232328 | Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID297339 | Binding affinity to human 5HT1A receptor | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID297330 | Displacement of [125I]IABN from human dopamine D2 receptor expressed in HEK293 cells | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17
| Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents. |
| AID749540 | Displacement of [125I]ABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma counting analysis | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID688179 | Selectivity ratio of dopamine D2 receptor to dopamine D3 receptor | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| High-affinity and selective dopamine D₃ receptor full agonists. |
| AID238643 | Binding affinity for human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID597451 | Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma counting | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID237455 | cLogD was determined | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID1232327 | Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells | 2015 | Journal of medicinal chemistry, Jul-23, Volume: 58, Issue:14
| Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. |
| AID597448 | Selectivity ratio Ki for human dopamine D2L receptor to Ki for human dopamine D3 receptor | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity. |
| AID238642 | Binding affinity for human dopamine D2 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1345833 | Human D3 receptor (Dopamine receptors) | 2007 | CNS drug reviews, Summer, Volume: 13, Issue:2
| Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |