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methoxsalen and Depression

methoxsalen has been researched along with Depression in 3 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Coumarins are a large family of compounds, of natural and synthetic origin, that exhibit a variety of pharmacological activities, including MAO inhibition."6.49A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease. ( Bari, SB; Deshmukh, PK; Donda, ST; Firke, SD; Patil, DA; Patil, PO, 2013)
"To investigate if the coumarins prolong the behavioral effects of nicotine, the forced swimming test (FST)-animal models of depression, and passive avoidance (PA) test-memory and learning paradigm were used."3.83In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone. ( Biala, G; Budzynska, B; Kruk-Slomka, M; Skalicka-Wozniak, K; Wydrzynska-Kuzma, M, 2016)
"Coumarins are a large family of compounds, of natural and synthetic origin, that exhibit a variety of pharmacological activities, including MAO inhibition."2.49A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease. ( Bari, SB; Deshmukh, PK; Donda, ST; Firke, SD; Patil, DA; Patil, PO, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Patil, PO1
Bari, SB1
Firke, SD1
Deshmukh, PK1
Donda, ST1
Patil, DA1
Kowalczyk, J1
Nakos-Bimpos, M1
Polissidis, A1
Dalla, C1
Kokras, N1
Skalicka-Wozniak, K2
Budzynska, B2
Kruk-Slomka, M1
Wydrzynska-Kuzma, M1
Biala, G1

Reviews

1 review available for methoxsalen and Depression

ArticleYear
A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2013, May-01, Volume: 21, Issue:9

    Topics: Alzheimer Disease; Coumarins; Depression; Drug Design; Humans; Models, Molecular; Molecular Structur

2013

Other Studies

2 other studies available for methoxsalen and Depression

ArticleYear
Xanthotoxin affects depression-related behavior and neurotransmitters content in a sex-dependent manner in mice.
    Behavioural brain research, 2021, 02-05, Volume: 399

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Female; Hippocampus; Male; Methoxsalen

2021
In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone.
    Psychopharmacology, 2016, Volume: 233, Issue:12

    Topics: 5-Methoxypsoralen; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Coumarins;

2016