pk 11195 has been researched along with Depression in 6 studies
PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Also, depression is common in adults with type 2 diabetes mellitus (T2DM)." | 1.43 | The antidepressant-like activity of AC-5216, a ligand for 18KDa translocator protein (TSPO), in an animal model of diabetes mellitus. ( Chen, JS; He, JL; Liu, X; Nie, H; Qiu, ZK; Shen, YG; Zeng, J; Zhang, GH, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Schubert, JJ | 1 |
| Veronese, M | 1 |
| Fryer, TD | 1 |
| Manavaki, R | 1 |
| Kitzbichler, MG | 1 |
| Nettis, MA | 1 |
| Mondelli, V | 1 |
| Pariante, CM | 1 |
| Bullmore, ET | 1 |
| Turkheimer, FE | 1 |
| Li, L | 1 |
| Wang, W | 1 |
| Zhang, LM | 1 |
| Jiang, XY | 1 |
| Sun, SZ | 1 |
| Sun, LJ | 1 |
| Guo, Y | 1 |
| Gong, J | 1 |
| Zhang, YZ | 1 |
| Wang, HL | 1 |
| Li, YF | 1 |
| Kudryashov, NV | 1 |
| Kalinina, TS | 1 |
| Shimshirt, AA | 1 |
| Korolev, AO | 1 |
| Volkova, AV | 1 |
| Voronina, TA | 1 |
| Wang, DS | 1 |
| Han, J | 1 |
| Li, S | 1 |
| Sun, T | 1 |
| Guo, YY | 1 |
| Kang, WB | 1 |
| Tian, Z | 1 |
| Zhao, JN | 1 |
| Liu, G | 1 |
| Liu, SB | 1 |
| Zhao, MG | 1 |
| Qiu, ZK | 1 |
| He, JL | 1 |
| Liu, X | 1 |
| Zhang, GH | 1 |
| Zeng, J | 1 |
| Nie, H | 1 |
| Shen, YG | 1 |
| Chen, JS | 1 |
| Raghavendra, V | 1 |
| Kaur, G | 1 |
| Kulkarni, SK | 1 |
6 other studies available for pk 11195 and Depression
| Article | Year |
|---|---|
A Modest Increase in
Topics: Body Mass Index; C-Reactive Protein; Depression; Depressive Disorder, Major; Humans; Isoquinolines; | 2021 |
Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects.
Topics: 5-alpha Reductase Inhibitors; Animals; Anxiety; Dentate Gyrus; Depression; Finasteride; Genetic Vect | 2017 |
Antidepressant-like effect of fluoxetine may depend on translocator protein activity and pretest session duration in forced swimming test in mice.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine; | 2018 |
Antidepressant-Like and Anxiolytic-Like Effects of ZBD-2, a Novel Ligand for the Translocator Protein (18 kDa).
Topics: Acetamides; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Disease Models | 2017 |
The antidepressant-like activity of AC-5216, a ligand for 18KDa translocator protein (TSPO), in an animal model of diabetes mellitus.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Carrier Proteins; Depression; Diabetes Mellitus, E | 2016 |
Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation.
Topics: Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Antioxidants; Benzodiazepinones; Bic | 2000 |