pyruvaldehyde has been researched along with Depression in 5 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anxiety and depression are common, highly comorbid psychiatric diseases that account for a large proportion of worldwide medical disability." | 1.51 | Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. ( Barkley-Levenson, AM; Cohen, SM; Dick, BL; Glatt, PF; Martinez, Y; Momper, JD; Palmer, AA; Perez, C; Siegel, D, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Szczepanik, JC | 2 |
| de Almeida, GRL | 2 |
| Cunha, MP | 2 |
| Dafre, AL | 2 |
| Selhorst, I | 1 |
| Schmitz, AE | 1 |
| Dos Santos, B | 1 |
| Heinrich, IA | 1 |
| de Paula, GC | 1 |
| De Bem, AF | 1 |
| Leal, RB | 1 |
| McMurray, KMJ | 1 |
| Ramaker, MJ | 1 |
| Barkley-Levenson, AM | 2 |
| Sidhu, PS | 1 |
| Elkin, PK | 1 |
| Reddy, MK | 1 |
| Guthrie, ML | 1 |
| Cook, JM | 1 |
| Rawal, VH | 1 |
| Arnold, LA | 1 |
| Dulawa, SC | 1 |
| Palmer, AA | 2 |
| Jang, S | 1 |
| Kwon, DM | 1 |
| Kwon, K | 1 |
| Park, C | 1 |
| Perez, C | 1 |
| Dick, BL | 1 |
| Glatt, PF | 1 |
| Martinez, Y | 1 |
| Siegel, D | 1 |
| Momper, JD | 1 |
| Cohen, SM | 1 |
5 other studies available for pyruvaldehyde and Depression
| Article | Year |
|---|---|
Repeated Methylglyoxal Treatment Depletes Dopamine in the Prefrontal Cortex, and Causes Memory Impairment and Depressive-Like Behavior in Mice.
Topics: Animals; Anti-Anxiety Agents; Depression; Dopamine; Female; Lactoylglutathione Lyase; Locomotion; Me | 2020 |
Methylglyoxal-Mediated Dopamine Depletion, Working Memory Deficit, and Depression-Like Behavior Are Prevented by a Dopamine/Noradrenaline Reuptake Inhibitor.
Topics: Animals; Bupropion; Depression; Dopamine; Dopamine Uptake Inhibitors; Female; Glutathione; Immobiliz | 2021 |
Identification of a novel, fast-acting GABAergic antidepressant.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Female; GABA Agents; Hindlimb Suspe | 2018 |
Generation and characterization of mouse knockout for glyoxalase 1.
Topics: Animals; Anxiety; Depression; Gene Deletion; Glutathione; Glycation End Products, Advanced; Glyoxal; | 2017 |
Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor.
Topics: Aminoquinolines; Animals; Antidepressive Agents; Brain; Depression; Drug Discovery; Enzyme Inhibitor | 2019 |