Page last updated: 2024-11-06

floxuridine and Depression

floxuridine has been researched along with Depression in 3 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"We have investigated the effect of istradefylline on depression-like behaviors using the rat learned helplessness (LH) model."3.80Antidepressant activity of the adenosine A2A receptor antagonist, istradefylline (KW-6002) on learned helplessness in rats. ( Jenner, P; Kanda, T; Kobayashi, M; Mori, A; Ohta, T; Shiozaki, S; Yamada, K, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamada, K1
Kobayashi, M1
Shiozaki, S1
Ohta, T1
Mori, A1
Jenner, P1
Kanda, T1
Allen-Mersh, TG1
Earlam, S1
Fordy, C1
Abrams, K1
Houghton, J1
Cleaver, JE1

Trials

1 trial available for floxuridine and Depression

ArticleYear
Quality of life and survival with continuous hepatic-artery floxuridine infusion for colorectal liver metastases.
    Lancet (London, England), 1994, Nov-05, Volume: 344, Issue:8932

    Topics: Anxiety; Aspartate Aminotransferases; Bilirubin; Carcinoembryonic Antigen; Cause of Death; Colorecta

1994

Other Studies

2 other studies available for floxuridine and Depression

ArticleYear
Antidepressant activity of the adenosine A2A receptor antagonist, istradefylline (KW-6002) on learned helplessness in rats.
    Psychopharmacology, 2014, Volume: 231, Issue:14

    Topics: Adenosine A2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Brain; Depressi

2014
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
    Radiation research, 1969, Volume: 37, Issue:2

    Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient;

1969