Page last updated: 2024-10-21

tacrine and Depression

tacrine has been researched along with Depression in 5 studies

Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Treatments in Alzheimer's disease include treatment of cognitive impairment and behavioral manifestations (agitation, depression, anxiety, delusions)."1.30[Drug therapy strategies in Alzheimer's disease]. ( Lacomblez, L, 1998)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Liu, W2
Wang, H2
Li, X2
Xu, Y2
Zhang, J1
Wang, W2
Gong, Q2
Qiu, X2
Zhu, J2
Mao, F2
Zhang, H2
Li, J2
Rani, A1
Singh, A1
Kaur, J1
Singh, G1
Bhatti, R1
Gumede, N1
Kisten, P1
Singh, P1
Kumar, V1
marotta, C1
Lacomblez, L1

Other Studies

5 other studies available for tacrine and Depression

ArticleYear
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholin

2018
1H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells.
    Bioorganic chemistry, 2021, Volume: 114

    Topics: Acetylcholinesterase; Animals; Anxiety; Brain; Butyrylcholinesterase; Chalcones; Cholinesterase Inhi

2021
Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation.
    ACS chemical neuroscience, 2017, 12-20, Volume: 8, Issue:12

    Topics: Alzheimer Disease; Animals; Antidepressive Agents; Cholinesterase Inhibitors; Cognition; Depression;

2017
Alzheimer's disease: how research is changing primary care management. Interview by Marc E. Weksler.
    Geriatrics, 1994, Volume: 49, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Depression; Diagnosis, Differential; Family; Family Prac

1994
[Drug therapy strategies in Alzheimer's disease].
    La Revue du praticien, 1998, Nov-01, Volume: 48, Issue:17

    Topics: Aggression; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Car

1998