tacrine has been researched along with Depression in 5 studies
Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
tacrine : A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatments in Alzheimer's disease include treatment of cognitive impairment and behavioral manifestations (agitation, depression, anxiety, delusions)." | 1.30 | [Drug therapy strategies in Alzheimer's disease]. ( Lacomblez, L, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, W | 2 |
| Wang, H | 2 |
| Li, X | 2 |
| Xu, Y | 2 |
| Zhang, J | 1 |
| Wang, W | 2 |
| Gong, Q | 2 |
| Qiu, X | 2 |
| Zhu, J | 2 |
| Mao, F | 2 |
| Zhang, H | 2 |
| Li, J | 2 |
| Rani, A | 1 |
| Singh, A | 1 |
| Kaur, J | 1 |
| Singh, G | 1 |
| Bhatti, R | 1 |
| Gumede, N | 1 |
| Kisten, P | 1 |
| Singh, P | 1 |
| Kumar, V | 1 |
| marotta, C | 1 |
| Lacomblez, L | 1 |
5 other studies available for tacrine and Depression
| Article | Year |
|---|---|
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholin | 2018 |
1H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells.
Topics: Acetylcholinesterase; Animals; Anxiety; Brain; Butyrylcholinesterase; Chalcones; Cholinesterase Inhi | 2021 |
Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation.
Topics: Alzheimer Disease; Animals; Antidepressive Agents; Cholinesterase Inhibitors; Cognition; Depression; | 2017 |
Alzheimer's disease: how research is changing primary care management. Interview by Marc E. Weksler.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Depression; Diagnosis, Differential; Family; Family Prac | 1994 |
[Drug therapy strategies in Alzheimer's disease].
Topics: Aggression; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Car | 1998 |