bromodeoxyuridine has been researched along with Depression in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 29 (48.33) | 29.6817 |
| 2010's | 26 (43.33) | 24.3611 |
| 2020's | 4 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| He, M; Xu, S; Zhang, X; Zhao, X; Zheng, X; Zhu, Z | 1 |
| Choi, HJ; Kim, HI; Kim, SH; Lim, J | 1 |
| Ge, J; Li, D; Li, P; Lin, X; Meng, P; Wang, X; Wang, Y; Yang, H; Zhang, X; Zhao, H | 1 |
| He, X; Lei, S; Li, C; Li, W; Liu, J; Meng, P; Wang, H; Wang, J; Wang, Y; Yang, H | 1 |
| Agari, T; Date, I; Kameda, M; Kin, I; Kin, K; Kuwahara, K; Morimoto, J; Okazaki, M; Sasaki, T; Tajiri, N; Umakoshi, M; Yasuhara, T | 1 |
| Brachman, RA; Herkenham, M; Lehmann, ML; Martinowich, K; Schloesser, RJ | 1 |
| Inoue, K; Llorens-Martín, M; Nishijima, T; Soya, H; Tejeda, GS; Torres-Alemán, I; Trejo, JL; Yamamura, Y | 1 |
| Cheng, RF; Fan, ZZ; Guo, J; Li, W; Peng, XD; Wang, YH; Yang, WD; Zhao, JY; Zhao, WH | 1 |
| Ben M'Barek, K; Benstaali, C; David, DJ; Gardier, AM; Godin, JD; Humbert, S; Orvoen, S; Pla, P; Saudou, F | 1 |
| Chen, YC; Gao, F; Hou, WG; Liu, L; Nie, H; Peng, ZW; Tan, Q; Wang, HN; Wang, L; Zhang, RG | 1 |
| Hasebe, S; Ogita, K; Shiba, T; Umeda, K; Yamaguchi, T; Yoneyama, M | 1 |
| Ding, JH; Geng, F; Hu, G; Lu, M; Yang, JZ | 1 |
| Filipkowski, RK; Jedynak, P; Kaczmarek, L; Kos, T; Sandi, C | 1 |
| Hen, R; Hill, AS; Sahay, A | 1 |
| Chan, CC; Chan, JN; Lau, BW; Po, KT; Siu, AM; So, KF | 1 |
| Guan, XT; Li, YC; Lin, WJ; Pan, YQ; Tang, MM | 1 |
| An, L; Chen, HX; Li, YF; Liu, XM; Yu, NJ; Yuan, L; Zhang, YZ; Zhao, N | 1 |
| Dar, DE; Gersner, R; Levit, O; Raizel, H; Richter-Levin, G; Toth, E; Wilf-Yarkoni, A; Zangen, A | 1 |
| Albert, M; Czéh, B; Frahm, J; Fuchs, E; Hesselink, MB; Michael, GJ; Michael-Titus, AT; Michaelis, T; Pudovkina, O; van der Hart, MG; Watanabe, T | 1 |
| Antonijevic, IA; Artymyshyn, RP; Craig, DA; David, DJ; Drew, M; Gardier, AM; Gerald, C; Guiard, BP; Guilloux, JP; Hen, R; Leonardo, ED; Marsteller, D; Mendez, I; Rainer, Q; Samuels, BA; Wang, JW | 1 |
| Guo, YJ; Sun, ZL; Wang, SH; Yang, BQ; Yuan, Y | 1 |
| Abel, T; Chung, H; Jang, DJ; Kaang, BK; Kim, B; Kim, H; Kim, SH; Kim, WR; Kim, YS; Ko, HG; Lee, JS; Lee, MY; Lee, N; Son, H; Son, J; Sun, W; Zhuo, M | 1 |
| Dar, DE; Stall, N; Taliaz, D; Zangen, A | 1 |
| Bjørnebekk, A; Brené, S; Mathé, AA | 3 |
| Chourbaji, S; Endres, M; Gass, P; Heuser, I; Inta, D; Kirste, I; Kronenberg, G | 1 |
| Gao, Y; Hou, B; Wu, Y; Xu, Z; Zhang, C; Zhang, Y; Zhao, S | 1 |
| Hanawa, T; Ito, N; Nagai, T; Oikawa, T; Yabe, T; Yamada, H | 1 |
| Kim, DH; Lee, S; Ryu, JH; Yoon, SH | 1 |
| Gulinello, ME; Mondie, CM; Vandergrift, KA; Weber, ET; Wilson, CL | 1 |
| Calandra, T; Castro, JE; Conboy, L; Lashuel, HA; Sakouhi-Ouertatani, H; Sandi, C; Varea, E | 1 |
| Baek, SB; Bahn, G; Kim, BK; Kim, CJ; Kim, KH; Kim, SE; Kim, TS; Ko, IG; Lee, J; Moon, SJ; Shin, MS; Sung, YH | 1 |
| Balu, DT; Blendy, JA; Hilario, MR; Ho, N; Lucki, I | 1 |
| Hellweg, R; Hühnchen, P; Klaissle, P; Lesemann, A; Pilhatsch, M; Reinel, C; Steiner, B; Winter, C | 1 |
| Chen, YC; Feng, SF; Shi, TY; Tan, QR; Wang, WN | 1 |
| Belzung, C; Minier, F; Rainer, Q; Surget, A; Tanti, A | 1 |
| Ding, JH; Gong, Y; Hu, G; Su, CJ; Sun, XL; Wu, FF | 1 |
| Belzung, C; Gaillard, P; Girault, V; Leman, S; Nollet, M; Tanti, A | 1 |
| Bardi, M; Franssen, CL; Kaufman, C; Lambert, KG; Rzucidlo, A; True, M | 1 |
| Abrial, E; Bétry, C; Etievant, A; Haddjeri, N; Lambás-Señas, L; Lucas, G; Scarna, H | 1 |
| Kajitani, K; Kamada, T; Katogi, A; Nakabeppu, Y; Nomaru, H; Ohnishi, YH; Ohnishi, YN; Sakumi, K; Shigeto, H; Takase, K; Yutsudo, N | 1 |
| Duman, RS; Malberg, JE | 1 |
| Becker, A; Bernstein, HG; Grecksch, G; Keilhoff, G; Wolf, G | 1 |
| Alleva, E; Aloe, L; Branchi, I; D'Andrea, I; Di Fausto, V; Fiore, M; Sietzema, J | 1 |
| Bisgaard, C; Jayatissa, MN; Papp, M; Tingström, A; Wiborg, O | 1 |
| Corona-Morales, AA; Escobar, A; Guadarrama, L; Rocha, L; Vega-Gonzalez, A; Zhang, L | 1 |
| Aznar, S; Husum, H; Høyer-Hansen, S; Larsen, MH; Mathé, AA; Mikkelsen, JD; Møller, A; Wörtwein, G | 1 |
| Beckoff, S; Dalla, C; Edgecomb, C; Mathew, J; Shors, TJ; Sisti, HM | 1 |
| Almond, S; Beaumont, V; Bilsland, JG; Bonnert, TP; Heavens, R; McAllister, G; Mead, A; Munoz-Sanjuan, I; Thakur, M; Waters, KA; Wheeldon, A; Whiting, P; Znamenskiy, P | 1 |
| Ben-Hur, T; Ben-Menachem-Zidon, O; Goshen, I; Kreisel, T; Licht, T; Weidenfeld, J; Yirmiya, R | 1 |
| Han, X; Hu, M; Hu, Y; Hua, Y; Luo, CX; Wang, B; Xu, JS; Zhou, QG; Zhu, DY; Zhu, XJ | 1 |
| Bjørnebekk, A; Brené, S; Gruber, SH; Mathé, AA | 1 |
| Becker, C; Benoliel, JJ; Blugeot, A; Hamon, M; Rivat, C; Zeau, B | 1 |
| Hutson, PH; Murray, F; Smith, DW | 1 |
| Belzung, C; Chalon, S; Griebel, G; Hen, R; Ibarguen-Vargas, Y; Leman, S; Saxe, M; Surget, A | 1 |
| Gruber, SH; Mathé, AA; Petersén, A; Wörtwein, G | 1 |
| Birnbaum, S; Eisch, AJ; Graham, A; Han, PL; Kim, KS; Krishnan, V; Lagace, DC; Mazei-Robison, MS; Nestler, EJ; Storm, DR; Zachariou, V | 1 |
| Bosker, FJ; den Boer, JA; Gladkevich, AV; Korf, J; Medema, HM; Tanke, MA | 1 |
| Cleaver, JE | 1 |
60 other study(ies) available for bromodeoxyuridine and Depression
| Article | Year |
|---|---|
A New Potential Antidepressant: Dexmedetomidine Alleviates Neuropathic Pain-Induced Depression by Increasing Neurogenesis in the Hippocampus.
Topics: Animals; Antidepressive Agents; Bromodeoxyuridine; Chronic Pain; Corticosterone; Depression; Dexmedetomidine; Hippocampus; Mice; Neuralgia; Neurogenesis; Sucrose | 2022 |
ERRγ Ligand Regulates Adult Neurogenesis and Depression-like Behavior in a LRRK2-G2019S-associated Young Female Mouse Model of Parkinson's Disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Estrogens; Female; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Ligands; Male; Mice; Mice, Transgenic; Mutation; Neurogenesis; Orphan Nuclear Receptors; Parkinson Disease; Protein Serine-Threonine Kinases; Tropomyosin | 2022 |
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Depression; Disease Models, Animal; Gastrointestinal Microbiome; Hippocampus; Homeostasis; Nerve Regeneration; Rats; Serotonin; Signal Transduction; Stress, Psychological | 2023 |
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Topics: Animals; Blood Glucose; Bromodeoxyuridine; Cell Self Renewal; Cyclin D1; Dentate Gyrus; Depression; Diabetes Mellitus, Experimental; Hippocampus; Leptin; Nestin; Rats; Rats, Sprague-Dawley | 2023 |
Hippocampal neurogenesis of Wistar Kyoto rats is congenitally impaired and correlated with stress resistance.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Exploratory Behavior; Hippocampus; Lateral Ventricles; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Rats; Rats, Inbred WKY; Rats, Wistar; Statistics as Topic; Sucrose; Swimming | 2017 |
Glucocorticoids orchestrate divergent effects on mood through adult neurogenesis.
Topics: Adaptation, Psychological; Adrenalectomy; Affect; Animals; Antimetabolites; Behavior, Animal; Bromodeoxyuridine; Corticosterone; Depression; Environment; Glucocorticoids; Housing, Animal; Mice; Mice, Inbred C57BL; Neurogenesis; Resilience, Psychological; Social Behavior; Social Dominance; Stress, Psychological | 2013 |
Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice.
Topics: Aging; Animals; Antimetabolites; Anxiety; Bromodeoxyuridine; Depression; Doublecortin Domain Proteins; Eating; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Motor Activity; Neurogenesis; Neuropeptides; Physical Conditioning, Animal; Running; Swimming; Weight Gain | 2013 |
[Antidepressant activities of flavonoids from Glycyrrhiza uralensis and its neurogenesis protective effect in rats].
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bromodeoxyuridine; Corticosterone; Depression; Flavonoids; Glycyrrhiza uralensis; Hindlimb Suspension; Hippocampus; Male; Neurogenesis; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Stress, Psychological; Swimming | 2012 |
Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.
Topics: Analysis of Variance; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Hippocampus; Huntingtin Protein; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuropeptides; Nuclear Proteins; Phosphorylation; Protein Transport; Serine | 2013 |
Anti-depressive mechanism of repetitive transcranial magnetic stimulation in rat: the role of the endocannabinoid system.
Topics: Analysis of Variance; Animals; bcl-2-Associated X Protein; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Depression; Disease Models, Animal; Exploratory Behavior; Food Preferences; Gene Expression Regulation; Hippocampus; Male; Piperidines; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Swimming; Transcranial Magnetic Stimulation | 2014 |
Lithium promotes neuronal repair and ameliorates depression-like behavior following trimethyltin-induced neuronal loss in the dentate gyrus.
Topics: Animals; Behavior, Animal; beta Catenin; Bromodeoxyuridine; Cell Survival; Dentate Gyrus; Depression; Disease Models, Animal; Hippocampus; Lithium; Male; Mice; Neurons; Neuroprotective Agents; Trimethyltin Compounds | 2014 |
Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis.
Topics: Animals; Antidepressive Agents; Body Weight; Bromodeoxyuridine; Cell Count; Corticosterone; Cytokines; Depression; Disease Models, Animal; Food Preferences; Freezing Reaction, Cataleptic; Hindlimb Suspension; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Propylamines; Stress, Psychological; Sweetening Agents; Swimming | 2014 |
Mice with ablated adult brain neurogenesis are not impaired in antidepressant response to chronic fluoxetine.
Topics: Animals; Antidepressive Agents; Bromodeoxyuridine; Chronic Disease; Cyclin D2; Depression; Exploratory Behavior; Fluoxetine; Hippocampus; Immunohistochemistry; Male; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurogenesis; Neuropsychological Tests; Swimming; Uncertainty | 2014 |
Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors.
Topics: Animals; Anxiety; bcl-2-Associated X Protein; Bromodeoxyuridine; Corticosterone; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Exploratory Behavior; Hippocampus; Hypothalamo-Hypophyseal System; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Pituitary-Adrenal System; Tamoxifen | 2015 |
Repeated, high-dose dextromethorphan treatment decreases neurogenesis and results in depression-like behavior in rats.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Proliferation; Dendrites; Depression; Dextromethorphan; Disease Models, Animal; Dose-Response Relationship, Drug; Doublecortin Domain Proteins; Doublecortin Protein; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hippocampus; Interpersonal Relations; Male; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Rats; Rats, Sprague-Dawley; Swimming; Time Factors | 2015 |
Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cytokines; Depression; Disease Models, Animal; Encephalitis; Exploratory Behavior; Food Preferences; Hindlimb Suspension; Hippocampus; Interleukin-1beta; Lipopolysaccharides; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Saccharin; Time Factors | 2016 |
The total flavonoids extracted from Xiaobuxin-Tang up-regulate the decreased hippocampal neurogenesis and neurotrophic molecules expression in chronically stressed rats.
Topics: Animals; Antimetabolites; Blotting, Western; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Chronic Disease; Cyclic AMP Response Element-Binding Protein; Depression; Drugs, Chinese Herbal; Flavonoids; Fluorescent Antibody Technique; Hippocampus; Immunohistochemistry; Nerve Growth Factors; Neurons; Plant Extracts; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Psychological; Up-Regulation | 2008 |
Age-dependent effects of chronic stress on brain plasticity and depressive behavior.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Depression; Disease Models, Animal; Exploratory Behavior; Food Preferences; Locomotion; Male; Neurogenesis; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Sucrose; Swimming | 2008 |
SONU20176289, a compound combining partial dopamine D(2) receptor agonism with specific serotonin reuptake inhibitor activity, affects neuroplasticity in an animal model for depression.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Brain Chemistry; Bromodeoxyuridine; Dentate Gyrus; Depression; Dopamine Agonists; Immunohistochemistry; Indoles; Magnetic Resonance Imaging; Male; Neuronal Plasticity; Norepinephrine; Piperazines; Prefrontal Cortex; Receptors, AMPA; Receptors, Dopamine D2; Selective Serotonin Reuptake Inhibitors; Social Environment; Stress, Psychological; Testis; Testosterone; Tupaiidae | 2008 |
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiety; Arrestins; beta-Arrestin 2; beta-Arrestins; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Corticosterone; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Drug Administration Schedule; Exploratory Behavior; Feeding Behavior; Fluoxetine; Gene Expression Regulation; GTP-Binding Protein alpha Subunit, Gi2; Hippocampus; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Radiation; Reaction Time; RNA, Messenger | 2009 |
Diabetes impairs hippocampal function via advanced glycation end product mediated new neuron generation in animals with diabetes-related depression.
Topics: Animals; Antimetabolites; Behavior, Animal; Blood Glucose; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cell Survival; Depression; Diabetes Mellitus, Experimental; Flow Injection Analysis; Glycation End Products, Advanced; Guanidines; Hippocampus; Immunohistochemistry; Male; Microscopy, Confocal; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2009 |
Induction of neuronal vascular endothelial growth factor expression by cAMP in the dentate gyrus of the hippocampus is required for antidepressant-like behaviors.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Line, Transformed; Chromatin Immunoprecipitation; CREB-Binding Protein; Cyclic AMP; Dentate Gyrus; Depression; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Exploratory Behavior; Feeding Behavior; Fluoxetine; Food Preferences; Gene Expression Regulation; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Neurons; Octopamine; Receptors, Biogenic Amine; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2009 |
Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Line; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Exploratory Behavior; Food Preferences; Glioma; Humans; Locomotion; Male; Maze Learning; Microinjections; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Statistics, Nonparametric; Sucrose; Sweetening Agents; Swimming; Transfection | 2010 |
The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression.
Topics: Animals; Antidepressive Agents; Bromodeoxyuridine; Cell Proliferation; Citalopram; Depression; Disease Models, Animal; Female; Hippocampus; Immunohistochemistry; In Situ Hybridization; Motor Activity; Neuronal Plasticity; Neuropeptide Y; Rats; Receptors, Neuropeptide Y; RNA, Messenger; Running | 2010 |
Reduced hippocampal neurogenesis in the GR(+/-) genetic mouse model of depression.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Differentiation; Depression; Disease Models, Animal; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factors; Neurogenesis; Phosphopyruvate Hydratase; Receptors, Glucocorticoid; Restraint, Physical; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors | 2009 |
Antidepressive behaviors induced byenriched environment might be modulated by glucocorticoid levels.
Topics: Adrenalectomy; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Environment; Glucocorticoids; Hindlimb Suspension; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neuropeptides; Radioimmunoassay; Swimming | 2009 |
A possible mechanism underlying an antidepressive-like effect of Kososan, a Kampo medicine, via the hypothalamic orexinergic system in the stress-induced depression-like model mice.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cyclopropanes; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hippocampus; Hypothalamus; Intracellular Signaling Peptides and Proteins; Magnoliopsida; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Milnacipran; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Orexins; Phytotherapy; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological | 2009 |
Sub-chronic administration of rimonabant causes loss of antidepressive activity and decreases doublecortin immunoreactivity in the mouse hippocampus.
Topics: Animals; Anti-Obesity Agents; Behavior, Animal; Bromodeoxyuridine; Cell Count; Depression; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Stress, Psychological | 2009 |
The chemotherapy agent, thioTEPA, yields long-term impairment of hippocampal cell proliferation and memory deficits but not depression-related behaviors in mice.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Conditioning, Operant; Depression; Disease Models, Animal; Hippocampus; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Recognition, Psychology; Thiotepa; Time Factors | 2010 |
Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors.
Topics: Acoustic Stimulation; Animals; Antidepressive Agents, Second-Generation; Anxiety; Bromodeoxyuridine; C-Reactive Protein; Cell Proliferation; Conditioning, Psychological; Corticosterone; Depression; Disease Models, Animal; Fear; Fluoxetine; Hippocampus; Macrophage Migration-Inhibitory Factors; Maze Learning; Memory Disorders; Mice; Mice, Knockout; Microscopy, Confocal; Nerve Tissue Proteins; Neurogenesis; Rats; Rats, Wistar; Receptors, Steroid; Spatial Behavior | 2011 |
The phosphodiesterase type-5 inhibitor, tadalafil, improves depressive symptoms, ameliorates memory impairment, as well as suppresses apoptosis and enhances cell proliferation in the hippocampus of maternal-separated rat pups.
Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Avoidance Learning; Bromodeoxyuridine; Carbolines; Caspase 3; Cell Proliferation; Dentate Gyrus; Depression; Disease Models, Animal; DNA Fragmentation; Female; Freezing Reaction, Cataleptic; In Situ Nick-End Labeling; Maternal Deprivation; Memory Disorders; Phosphodiesterase 5 Inhibitors; Pregnancy; Rats; Rats, Sprague-Dawley; Reaction Time; Swimming; Tadalafil | 2011 |
Depressive phenotypes evoked by experimental diabetes are reversed by insulin.
Topics: Analysis of Variance; Animals; Blood Glucose; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Corticosterone; Depression; Diabetes Mellitus, Experimental; Disease Models, Animal; Electric Stimulation; Hindlimb Suspension; Hippocampus; Hypoglycemic Agents; Immobility Response, Tonic; Insulin; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Phenotype; Self Administration | 2012 |
MPTP-induced hippocampal effects on serotonin, dopamine, neurotrophins, adult neurogenesis and depression-like behavior are partially influenced by fluoxetine in adult mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Conditioning, Operant; Dark Adaptation; Depression; Disease Models, Animal; Dopamine; Enzyme-Linked Immunosorbent Assay; Female; Fluoxetine; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; Intermediate Filament Proteins; Mice; Mice, Transgenic; MPTP Poisoning; Nerve Growth Factors; Nerve Tissue Proteins; Nestin; Random Allocation; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT1; Reflex, Startle; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin | 2012 |
Long-lasting effects of chronic rTMS to treat chronic rodent model of depression.
Topics: Adrenocorticotropic Hormone; Anhedonia; Animals; Antidepressive Agents, Second-Generation; Antimetabolites; Blotting, Western; Body Weight; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cyclohexanols; Depression; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Food Preferences; Hydrocortisone; Male; MAP Kinase Signaling System; Motor Activity; Neurogenesis; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming; Transcranial Magnetic Stimulation; Venlafaxine Hydrochloride | 2012 |
Differential environmental regulation of neurogenesis along the septo-temporal axis of the hippocampus.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Antimetabolites; Anxiety; Bromodeoxyuridine; Cell Proliferation; Depression; Dose-Response Relationship, Drug; Eating; Environment; Fluoxetine; Grooming; Hair; Hippocampus; Male; Memory; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Recognition, Psychology; Stress, Psychological | 2012 |
Female early adult depression results in detrimental impacts on the behavioral performance and brain development in offspring.
Topics: Age Factors; Animals; Animals, Newborn; Astrocytes; Behavior, Animal; Body Weight; Brain; Bromodeoxyuridine; Cell Proliferation; Corticosterone; Depression; Disease Models, Animal; Female; Food Preferences; Freezing Reaction, Cataleptic; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Glucocorticoid; Reflex; Sucrose; Swimming | 2012 |
Neurogenesis-independent antidepressant-like effects on behavior and stress axis response of a dual orexin receptor antagonist in a rodent model of depression.
Topics: Acetamides; Animals; Antidepressive Agents; Behavior, Animal; Biomarkers; Bromodeoxyuridine; Cell Proliferation; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Fluoxetine; Hypothalamo-Hypophyseal System; Intracellular Signaling Peptides and Proteins; Isoquinolines; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Orexin Receptors; Orexins; Pituitary-Adrenal System; Receptors, G-Protein-Coupled; Receptors, Neuropeptide | 2012 |
Effort-Based Reward (EBR) training enhances neurobiological efficiency in a problem-solving task: insights for depression therapies.
Topics: Analysis of Variance; Animals; Antimetabolites; Behavior, Animal; Bromodeoxyuridine; Cognition; Conditioning, Operant; Dentate Gyrus; Depression; Hippocampus; Immunohistochemistry; Male; Maze Learning; Models, Neurological; Neuronal Plasticity; Physical Exertion; Problem Solving; Proto-Oncogene Proteins c-fos; Psychomotor Performance; Rats; Rats, Long-Evans; Reward | 2013 |
Protein kinase C regulates mood-related behaviors and adult hippocampal cell proliferation in rats.
Topics: Affect; Animals; Antimetabolites; Anxiety; Behavior, Animal; Bipolar Disorder; Bromodeoxyuridine; Cell Count; Cell Proliferation; Central Nervous System Stimulants; Dentate Gyrus; Depression; Dextroamphetamine; Hippocampus; Immunohistochemistry; Microinjections; Motor Activity; Neuronal Plasticity; Protein Kinase C; Protein Kinase Inhibitors; Rats; Risk-Taking; Signal Transduction; Stereotaxic Techniques; Swimming | 2013 |
fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Depression; Disease Models, Animal; Doublecortin Domain Proteins; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Microtubule-Associated Proteins; Mutation; Neurogenesis; Neuropeptides; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-fos | 2013 |
Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Division; Conditioning, Operant; Corticosterone; Depression; Disease Models, Animal; Electroshock; Escape Reaction; Fluoxetine; Helplessness, Learned; Hippocampus; Male; Nerve Growth Factors; Nuclear Proteins; Radiation-Sensitizing Agents; Rats; Rats, Sprague-Dawley; Reaction Time; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stress, Psychological; Time Factors | 2003 |
The antidepressant effect of running is associated with increased hippocampal cell proliferation.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Dynorphins; Enkephalins; Freezing Reaction, Cataleptic; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Running; Substance P | 2005 |
Running has differential effects on NPY, opiates, and cell proliferation in an animal model of depression and controls.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Dynorphins; Enkephalins; Exercise Therapy; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Neuropeptide Y; Rats; Rats, Inbred Strains; Running | 2006 |
Cell proliferation is influenced by bulbectomy and normalized by imipramine treatment in a region-specific manner.
Topics: Amygdala; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bromodeoxyuridine; Cell Proliferation; Depression; Disease Models, Animal; Hippocampus; Imipramine; Immunohistochemistry; In Situ Nick-End Labeling; Indoles; Male; Motor Activity; Nerve Tissue Proteins; Neurons; Olfactory Bulb; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors | 2006 |
Early social enrichment augments adult hippocampal BDNF levels and survival of BrdU-positive cells while increasing anxiety- and "depression"-like behavior.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Depression; Environment; Exploratory Behavior; Female; Hippocampus; Immobility Response, Tonic; Interpersonal Relations; Male; Maze Learning; Mice; Motor Activity; Neurons; Reaction Time; Swimming | 2006 |
Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bromodeoxyuridine; Cell Count; Citalopram; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Hippocampus; Immunohistochemistry; Male; Neurons; Phosphopyruvate Hydratase; Rats; Statistics as Topic; Stress, Physiological; Sucrose | 2006 |
Rats subjected to extended L-tryptophan restriction during early postnatal stage exhibit anxious-depressive features and structural changes.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain; Bromodeoxyuridine; Cell Count; Depression; Diet, Protein-Restricted; Disease Models, Animal; Immunohistochemistry; Male; Maze Learning; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin; Silver Staining; Swimming; Tryptophan; Tryptophan Hydroxylase | 2006 |
Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression?
Topics: Aging; Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Survival; Depression; Hippocampus; Immunohistochemistry; Nerve Fibers; Neuronal Plasticity; Neurons; Neuropeptide Y; Presynaptic Terminals; Rats; Rats, Inbred Strains; Serotonin | 2006 |
Neurogenesis and helplessness are mediated by controllability in males but not in females.
Topics: Animals; Avoidance Learning; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Female; Helplessness, Learned; Hippocampus; Male; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Reaction Time; Sex Characteristics; Stress, Psychological | 2007 |
Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications.
Topics: Anaplastic Lymphoma Kinase; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Bromodeoxyuridine; Cell Proliferation; Chromatography, High Pressure Liquid; Depression; Dopamine; Female; Flow Cytometry; Hindlimb Suspension; Immunohistochemistry; Male; Mice; Mice, Knockout; Motor Activity; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Recognition, Psychology; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Swimming; Thymidine | 2008 |
Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression.
Topics: Adrenal Cortex; Animals; Brain; Bromodeoxyuridine; Chronic Disease; Depression; Enzyme-Linked Immunosorbent Assay; Hippocampus; Interleukin-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Receptors, Interleukin-1; Stress, Psychological | 2008 |
Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bromodeoxyuridine; Cell Proliferation; Depression; Drug Interactions; Enzyme Inhibitors; Hindlimb Suspension; Hippocampus; Indazoles; Male; Mice; Mice, Knockout; Neurons; Nitric Oxide Synthase Type I; Stress, Psychological; Time Factors; Zidovudine | 2007 |
Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Disease Models, Animal; Female; Gene Expression Regulation; Hippocampus; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, Serotonin; Social Isolation | 2007 |
Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Bromodeoxyuridine; Cell Proliferation; Cholecystokinin; Corticosterone; Depression; Disease Models, Animal; Dominance-Subordination; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Imipramine; Male; Microdialysis; Phosphopyruvate Hydratase; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Social Environment; Swimming | 2008 |
Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice.
Topics: Adrenal Glands; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimetabolites; Anxiety; Behavior, Animal; Bromodeoxyuridine; Cell Proliferation; Chemistry, Pharmaceutical; Corticosterone; Depression; Fluoxetine; Hippocampus; Imipramine; Immunohistochemistry; Lighting; Male; Mice; Organ Size; Swimming | 2008 |
Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Bromodeoxyuridine; Cell Count; Cell Proliferation; Corticotropin-Releasing Hormone; Depression; Disease Models, Animal; Exploratory Behavior; Hemibody Irradiation; Hippocampus; Hydrocarbons, Halogenated; Indoles; Male; Mice; Mice, Inbred BALB C; Motor Activity; Neurons; Pyrrolidines; Reaction Time; Thiazines; Time Factors | 2008 |
Escitalopram reduces increased hippocampal cytogenesis in a genetic rat depression model.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Bromodeoxyuridine; Cell Proliferation; Citalopram; Depression; Disease Models, Animal; Hippocampus; Maternal Deprivation; Neurons; Rats; Rats, Inbred Strains; Swimming | 2008 |
Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Calcium; Cell Proliferation; Depression; Disease Models, Animal; Female; Food Preferences; Habituation, Psychophysiologic; Interpersonal Relations; Male; Mice; Mice, Knockout; Motor Activity; Phenotype; Signal Transduction; Sucrose; Swimming | 2008 |
Lymphocyte glucocorticoid receptor resistance and depressive symptoms severity: a preliminary report.
Topics: Bromodeoxyuridine; Cell Count; Cell Proliferation; Depression; Dexamethasone; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Psychiatric Status Rating Scales; Receptors, Glucocorticoid; Regression Analysis | 2008 |
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Depression; DNA; DNA Replication; Floxuridine; Gentian Violet; HeLa Cells; Humans; Hydroxyurea; Iodoacetates; L Cells; Mice; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |