oxidopamine has been researched along with Depression in 35 studies
Oxidopamine: A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
oxidopamine : A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD)." | 7.88 | Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease. ( Abuirmeileh, AN; Alzoubi, KH; Mokhemer, E, 2018) |
| "Hesperidin treatment was also capable to increase striatal levels of dopamine and its metabolite 3,4-dihydroxyphenylacetic acid and protects against the impairment of dopaminergic neurons in the substantia nigra pars compacta (SNpc) (p < 0." | 5.56 | Hesperidin Ameliorates Anxiety-Depressive-Like Behavior in 6-OHDA Model of Parkinson's Disease by Regulating Striatal Cytokine and Neurotrophic Factors Levels and Dopaminergic Innervation Loss in the Striatum of Mice. ( Antunes, MS; Araújo, SM; Boeira, SP; Bortolotto, VC; Cattelan Souza, L; Ladd, AABL; Ladd, FVL; Moreira, AL; Nogueira, CW; Prigol, M; Silva, MRP, 2020) |
| "Parkinson's disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal deficits (e." | 5.48 | Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease. ( Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M, 2018) |
| "The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD)." | 3.88 | Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease. ( Abuirmeileh, AN; Alzoubi, KH; Mokhemer, E, 2018) |
| "Hypericum perforatum is considered an effective alternative to the synthetic antidepressants in the treatment of mild-to-moderate depression." | 3.71 | Serotonin, norepinephrine and dopamine involvement in the antidepressant action of hypericum perforatum. ( Calapai, G; Caputi, A; Crupi, A; De Sarro, G; Firenzuoli, F; Inferrera, G; Parisi, A; Squadrito, F, 2001) |
| "The objective of this study was to investigate whether bilateral dopamine depletion within the medial prefrontal cortex affects depression state, as well as the antidepressant efficacy of desipramine, in the forced swimming test." | 3.70 | Prefrontocortical dopamine depletion induces antidepressant-like effects in rats and alters the profile of desipramine during Porsolt's test. ( Espejo, EF; Miñano, FJ, 1999) |
| "The influence of alpha 2-adrenoceptor blockade on the activity of desipramine in an experimental model of depression was studied by using idazoxan and 1-(pyrimidinyl)piperazine (1-PP)." | 3.68 | Alpha 2-adrenoceptor blockade prevents the effect of desipramine in the forced swimming test. ( Cervo, L; Grignaschi, G; Samanin, R, 1990) |
| "The most common features of Parkinson's disease (PD) are motor impairments, but many patients also present depression and memory impairment." | 1.62 | Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease. ( Andreatini, R; Da Cunha, C; Hocayen, PAS; Kanazawa, LKS; Miyoshi, E; Takahashi, RN; Vecchia, DD; Vital, MABF; Wendler, E, 2021) |
| "Hesperidin treatment was also capable to increase striatal levels of dopamine and its metabolite 3,4-dihydroxyphenylacetic acid and protects against the impairment of dopaminergic neurons in the substantia nigra pars compacta (SNpc) (p < 0." | 1.56 | Hesperidin Ameliorates Anxiety-Depressive-Like Behavior in 6-OHDA Model of Parkinson's Disease by Regulating Striatal Cytokine and Neurotrophic Factors Levels and Dopaminergic Innervation Loss in the Striatum of Mice. ( Antunes, MS; Araújo, SM; Boeira, SP; Bortolotto, VC; Cattelan Souza, L; Ladd, AABL; Ladd, FVL; Moreira, AL; Nogueira, CW; Prigol, M; Silva, MRP, 2020) |
| "Parkinson's disease is a chronic neurodegenerative disorder characterized by cardinal motor features, such as bradykinesia, but also vocal deficits (e." | 1.48 | Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease. ( Andreatini, R; Bruginski, E; Campos, FR; de Almeida Soares Hocayen, P; Kanazawa, LKS; Miyoshi, E; Schwarting, RKW; Stern, CAJ; Vecchia, DD; Vital, MABF; Wendler, E; Wöhr, M, 2018) |
| "Depression is a common co-morbid condition most often observed in subjects with mild cognitive impairment (MCI) and during the early stages of Alzheimer's disease (AD)." | 1.43 | Depressive-like behavior observed with a minimal loss of locus coeruleus (LC) neurons following administration of 6-hydroxydopamine is associated with electrophysiological changes and reversed with precursors of norepinephrine. ( Franklin, A; Miguelez, C; Raskind, MA; Sikkema, C; Szot, P; Ugedo, L; Vidaurrazaga, I; Wang, Y; Wilkinson, CW, 2016) |
| "Depression is a common symptom in Parkinson's disease (PD); however, its pathophysiology is unclear." | 1.43 | Serotonin7 receptors in the lateral habenular nucleus regulate depressive-like behaviors in the hemiparkinsonian rats. ( Du, CX; Han, LN; Liu, J; Sun, YN; Wang, T; Zhang, J; Zhang, L; Zhang, YM, 2016) |
| "Depression is a common symptom in Parkinson's disease (PD), but its pathophysiology remains unclear." | 1.40 | Activation of prelimbic 5-HT1A receptors produces antidepressant-like effects in a unilateral rat model of Parkinson's disease. ( Chen, L; Guo, Y; Hui, YP; Liu, J; Qiao, HF; Wang, Y; Zhang, L; Zhang, QJ, 2014) |
| " The present study indicates that already a moderate lesion of dopaminergic neurons induces "depressive-like" behaviour in animals which is reversed by chronic administration of the antiparkinsonian drug, pramipexole." | 1.40 | Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease. ( Berghauzen-Maciejewska, K; Dziubina, A; Głowacka, U; Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J, 2014) |
| "Depression is a neuropsychiatric disorder that is commonly found in patients with Parkinson's disease (PD)." | 1.40 | Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease. ( Dal Pont, GC; Luciano, TF; Paganini, CS; Pinho, RA; Pozzi, BG; Quevedo, J; Souza, CT; Souza, PS; Tuon, T; Valvassori, SS, 2014) |
| "Depression is a frequent comorbid disorder in Parkinson's disease (PD) which may precede appearance of its motor symptoms by several years." | 1.37 | Partial lesion of the dopaminergic innervation of the ventral striatum induces "depressive-like" behavior of rats. ( Berghauzen, K; Dziubina, A; Gołembiowska, K; Kolasiewicz, W; Kuter, K; Ossowska, K; Schulze, G; Wardas, J, 2011) |
| "Depression is a frequently encountered non-motor feature of Parkinson's disease (PD) and it can have a significant impact on patient's quality of life." | 1.36 | Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine. ( Andreatini, R; Barbieiro, J; Dombrowski, PA; Lima, MM; Santiago, RM; Vital, MA, 2010) |
| "Depression is the most common psychiatric complication in Parkinson's disease (PD)." | 1.34 | Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats. ( Juckel, G; Klein, J; Kupsch, A; Lee, T; Morgenstern, R; Mundt, A; Petrus, D; von Rumohr, A; Winter, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.57) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 23 (65.71) | 24.3611 |
| 2020's | 5 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Cunha, AM | 1 |
| Teixeira, FG | 1 |
| Guimarães, MR | 1 |
| Esteves, M | 1 |
| Pereira-Mendes, J | 1 |
| Soares, AR | 1 |
| Almeida, A | 1 |
| Sousa, N | 1 |
| Salgado, AJ | 1 |
| Leite-Almeida, H | 1 |
| G, A | 1 |
| O, P | 1 |
| E, CM | 1 |
| M, GR | 1 |
| Antunes, MS | 1 |
| Cattelan Souza, L | 1 |
| Ladd, FVL | 1 |
| Ladd, AABL | 1 |
| Moreira, AL | 1 |
| Bortolotto, VC | 1 |
| Silva, MRP | 1 |
| Araújo, SM | 1 |
| Prigol, M | 1 |
| Nogueira, CW | 1 |
| Boeira, SP | 1 |
| Vecchia, DD | 2 |
| Kanazawa, LKS | 2 |
| Wendler, E | 2 |
| Hocayen, PAS | 1 |
| Vital, MABF | 4 |
| Takahashi, RN | 3 |
| Da Cunha, C | 2 |
| Miyoshi, E | 2 |
| Andreatini, R | 5 |
| Lyu, S | 1 |
| Guo, Y | 4 |
| Zhang, L | 6 |
| Tang, G | 1 |
| Li, R | 1 |
| Yang, J | 1 |
| Gao, S | 1 |
| Li, W | 1 |
| Liu, J | 6 |
| Bonato, JM | 1 |
| Bassani, TB | 2 |
| Milani, H | 1 |
| de Oliveira, RMW | 1 |
| de Almeida Soares Hocayen, P | 1 |
| Bruginski, E | 1 |
| Campos, FR | 1 |
| Stern, CAJ | 1 |
| Wöhr, M | 1 |
| Schwarting, RKW | 1 |
| Souza, LC | 1 |
| Martynhak, BJ | 1 |
| Turnes, JM | 1 |
| Machado, MM | 1 |
| Moura, E | 1 |
| Kumari, N | 1 |
| Agrawal, S | 1 |
| Kumari, R | 1 |
| Sharma, D | 1 |
| Luthra, PM | 1 |
| Alzoubi, KH | 1 |
| Mokhemer, E | 1 |
| Abuirmeileh, AN | 1 |
| Marques, NF | 1 |
| Binder, LB | 1 |
| Roversi, K | 1 |
| Sampaio, TB | 1 |
| Constantino, LC | 1 |
| Prediger, RD | 2 |
| Tasca, CI | 1 |
| Santiago, RM | 2 |
| Barbiero, J | 1 |
| Gradowski, RW | 1 |
| Bochen, S | 1 |
| Lima, MM | 2 |
| Vital, MA | 2 |
| Hui, YP | 1 |
| Zhang, QJ | 3 |
| Chen, L | 3 |
| Qiao, HF | 1 |
| Wang, Y | 5 |
| Berghauzen-Maciejewska, K | 1 |
| Kuter, K | 2 |
| Kolasiewicz, W | 2 |
| Głowacka, U | 1 |
| Dziubina, A | 2 |
| Ossowska, K | 2 |
| Wardas, J | 2 |
| Tuon, T | 1 |
| Valvassori, SS | 1 |
| Dal Pont, GC | 1 |
| Paganini, CS | 1 |
| Pozzi, BG | 1 |
| Luciano, TF | 1 |
| Souza, PS | 1 |
| Quevedo, J | 1 |
| Souza, CT | 1 |
| Pinho, RA | 1 |
| Han, LN | 2 |
| Li, LB | 1 |
| Sun, YN | 4 |
| Zhang, YM | 3 |
| Chiu, WH | 1 |
| Depboylu, C | 1 |
| Hermanns, G | 1 |
| Maurer, L | 1 |
| Windolph, A | 1 |
| Oertel, WH | 1 |
| Ries, V | 1 |
| Höglinger, GU | 1 |
| Matheus, FC | 1 |
| Rial, D | 1 |
| Real, JI | 1 |
| Lemos, C | 1 |
| Bertoglio, LJ | 1 |
| Cunha, RA | 1 |
| Szot, P | 1 |
| Franklin, A | 1 |
| Miguelez, C | 1 |
| Vidaurrazaga, I | 1 |
| Ugedo, L | 1 |
| Sikkema, C | 1 |
| Wilkinson, CW | 1 |
| Raskind, MA | 1 |
| Silva, TP | 1 |
| Poli, A | 1 |
| Hara, DB | 1 |
| Du, CX | 3 |
| Wang, T | 2 |
| Zhang, J | 3 |
| Yao, L | 1 |
| Yu, SQ | 1 |
| Dallé, E | 1 |
| Daniels, WM | 1 |
| Mabandla, MV | 1 |
| Lv, SX | 1 |
| Barbieiro, J | 1 |
| Dombrowski, PA | 1 |
| Eskow Jaunarajs, KL | 1 |
| Dupre, KB | 1 |
| Ostock, CY | 1 |
| Button, T | 1 |
| Deak, T | 1 |
| Bishop, C | 1 |
| Casas, S | 1 |
| García, S | 1 |
| Cabrera, R | 1 |
| Nanfaro, F | 1 |
| Escudero, C | 1 |
| Yunes, R | 1 |
| Gołembiowska, K | 1 |
| Schulze, G | 1 |
| Berghauzen, K | 1 |
| Chenu, F | 1 |
| Dailly, E | 1 |
| Bourin, M | 1 |
| Winter, C | 1 |
| von Rumohr, A | 1 |
| Mundt, A | 1 |
| Petrus, D | 1 |
| Klein, J | 1 |
| Lee, T | 1 |
| Morgenstern, R | 1 |
| Kupsch, A | 1 |
| Juckel, G | 1 |
| Espejo, EF | 1 |
| Miñano, FJ | 1 |
| Calapai, G | 1 |
| Crupi, A | 1 |
| Firenzuoli, F | 1 |
| Inferrera, G | 1 |
| Squadrito, F | 1 |
| Parisi, A | 1 |
| De Sarro, G | 1 |
| Caputi, A | 1 |
| Rénéric, JP | 1 |
| Bouvard, M | 1 |
| Stinus, L | 1 |
| Cervo, L | 2 |
| Grignaschi, G | 2 |
| Samanin, R | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Different Physical Therapies and Dance on Clinical and Functional Parameters, Muscle Quality, Pendular Mechanism of the Gait and Brain-derived Neurotrophic Factor in People With Parkinson's Disease[NCT03860649] | 100 participants (Actual) | Interventional | 2018-08-01 | Active, not recruiting | |||
| The Impact of Video Dance Class and Unsupervised Physical Activity on Parkinson's People During the Covid-19 Pandemic: Interventional[NCT04422353] | 60 participants (Anticipated) | Interventional | 2020-05-01 | Recruiting | |||
| Neuroactive Steroids in Acute Ischemic Stroke: Association With Cognitive, Functional and Neurological Outcomes.[NCT02914106] | 60 participants (Actual) | Observational | 2014-06-30 | Completed | |||
| Changes in Plasma Cortisol, Brain-derived Neurotrophic Factor, and Nitrites in Patients With Acute Ischemic Stroke[NCT03242304] | 40 participants (Actual) | Observational | 2016-04-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
35 other studies available for oxidopamine and Depression
| Article | Year |
|---|---|
Unilateral accumbal dopamine depletion affects decision-making in a side-specific manner.
Topics: Animals; Anxiety; Behavior, Animal; Decision Making; Depression; Dopaminergic Neurons; Impulsive Beh | 2020 |
Reduction of dopaminergic transmission in the globus pallidus increases anxiety-like behavior without altering motor activity.
Topics: Animals; Anxiety; Brain; Depression; Dopamine; Dopamine Agonists; Globus Pallidus; Male; Motor Activ | 2020 |
Hesperidin Ameliorates Anxiety-Depressive-Like Behavior in 6-OHDA Model of Parkinson's Disease by Regulating Striatal Cytokine and Neurotrophic Factors Levels and Dopaminergic Innervation Loss in the Striatum of Mice.
Topics: Animals; Anxiety; Behavior, Animal; Corpus Striatum; Cytokines; Depression; Dopaminergic Neurons; He | 2020 |
Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Imipramine; Ketamine; Male; Memory, S | 2021 |
Downregulation of astroglial glutamate transporter GLT-1 in the lateral habenula is associated with depressive-like behaviors in a rat model of Parkinson's disease.
Topics: Animals; Astrocytes; Depression; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Tran | 2021 |
Pioglitazone reduces mortality, prevents depressive-like behavior, and impacts hippocampal neurogenesis in the 6-OHDA model of Parkinson's disease in rats.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Hippocampus; Male; Mortality; Ne | 2018 |
Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6-OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease.
Topics: Anhedonia; Animals; Depression; Disease Models, Animal; Gait; Imipramine; Ketamine; Male; Nerve Dege | 2018 |
Agomelatine's effect on circadian locomotor rhythm alteration and depressive-like behavior in 6-OHDA lesioned rats.
Topics: Acetamides; Animals; Circadian Rhythm; Depression; Exploratory Behavior; Food Preferences; Hypnotics | 2018 |
Neuroprotective effect of IDPU (1-(7-imino-3-propyl-2,3-dihydrothiazolo [4,5-d]pyrimidin-6(7H)-yl)urea) in 6-OHDA induced rodent model of hemiparkinson's disease.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Depression; Disease Models, Animal; Male; Neuroprot | 2018 |
Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Depression; Etazolate; Hippocampus; Learning Disabilities; Male; Memo | 2018 |
Guanosine prevents depressive-like behaviors in rats following bilateral dorsolateral striatum lesion induced by 6-hydroxydopamine.
Topics: Anhedonia; Animals; Brain; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Guanosine; | 2019 |
Induction of depressive-like behavior by intranigral 6-OHDA is directly correlated with deficits in striatal dopamine and hippocampal serotonin.
Topics: Adrenergic Agents; Animals; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Explorato | 2014 |
Activation of prelimbic 5-HT1A receptors produces antidepressant-like effects in a unilateral rat model of Parkinson's disease.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Depression; Dietary Sucrose; | 2014 |
Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease.
Topics: Animals; Antidepressive Agents; Benzothiazoles; Depression; Disease Models, Animal; Dopamine Agonist | 2014 |
Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Exercise Therapy; Ma | 2014 |
Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Exercise Therapy; Ma | 2014 |
Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Exercise Therapy; Ma | 2014 |
Physical training prevents depressive symptoms and a decrease in brain-derived neurotrophic factor in Parkinson's disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Exercise Therapy; Ma | 2014 |
Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat.
Topics: Action Potentials; Adrenergic Agents; Animals; Apomorphine; Depression; Disease Models, Animal; Dopa | 2015 |
Long-term treatment with L-DOPA or pramipexole affects adult neurogenesis and corresponding non-motor behavior in a mouse model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Anxiety; Benzothiazoles; Depression; Hippocampus; Levodopa; Male; Mic | 2015 |
Temporal Dissociation of Striatum and Prefrontal Cortex Uncouples Anhedonia and Defense Behaviors Relevant to Depression in 6-OHDA-Lesioned Rats.
Topics: Anhedonia; Animals; Behavior, Animal; Corpus Striatum; Depression; Dopamine Plasma Membrane Transpor | 2016 |
Depressive-like behavior observed with a minimal loss of locus coeruleus (LC) neurons following administration of 6-hydroxydopamine is associated with electrophysiological changes and reversed with precursors of norepinephrine.
Topics: Action Potentials; Adrenergic Agents; Animals; Catecholamines; Depression; Disease Models, Animal; D | 2016 |
Time course study of microglial and behavioral alterations induced by 6-hydroxydopamine in rats.
Topics: Acetylglucosaminidase; Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Corpus Striatum; Dep | 2016 |
Serotonin7 receptors in the lateral habenular nucleus regulate depressive-like behaviors in the hemiparkinsonian rats.
Topics: Animals; Depression; Disease Models, Animal; Dopamine; Habenula; Hippocampus; Locomotion; Male; Nore | 2016 |
Activation and blockade of prelimbic 5-HT6 receptors produce different effects on depressive-like behaviors in unilateral 6-hydroxydopamine-induced Parkinson's rats.
Topics: Animals; Depression; Injections, Intraventricular; Male; Methylamines; Oxidopamine; Parkinsonian Dis | 2016 |
Fluvoxamine maleate normalizes striatal neuronal inflammatory cytokine activity in a Parkinsonian rat model associated with depression.
Topics: Age Factors; Animals; Animals, Newborn; Anti-Anxiety Agents; Corpus Striatum; Cytokines; Depression; | 2017 |
Involvement of lateral habenula α1 subunit-containing GABA
Topics: Action Potentials; Animals; Apomorphine; Depression; Dopamine Agonists; GABA Antagonists; GABA-A Rec | 2017 |
Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Behavior, Animal; Depre | 2010 |
Behavioral and neurochemical effects of chronic L-DOPA treatment on nonmotor sequelae in the hemiparkinsonian rat.
Topics: Amygdala; Animals; Anxiety; Behavioral Research; Biogenic Monoamines; Chromatography, High Pressure | 2010 |
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male; | 2011 |
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male; | 2011 |
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male; | 2011 |
Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats.
Topics: Amphetamine; Animals; Antidepressive Agents; Apomorphine; Cues; Depression; Dopamine Agonists; Male; | 2011 |
Partial lesion of the dopaminergic innervation of the ventral striatum induces "depressive-like" behavior of rats.
Topics: Animals; Basal Ganglia; Depression; Dopamine; Dopaminergic Neurons; Male; Motor Activity; Oxidopamin | 2011 |
Effect of antidepressant drugs on 6-OHDA-treated mice in the FST.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2007 |
Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats.
Topics: Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Anim | 2007 |
Prefrontocortical dopamine depletion induces antidepressant-like effects in rats and alters the profile of desipramine during Porsolt's test.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain Chemistry; Depression; Desipramin | 1999 |
Serotonin, norepinephrine and dopamine involvement in the antidepressant action of hypericum perforatum.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Brain Chemistry; Depressio | 2001 |
In the rat forced swimming test, NA-system mediated interactions may prevent the 5-HT properties of some subacute antidepressant treatments being expressed.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Depression | 2002 |
Alpha 2-adrenoceptor blockade prevents the effect of desipramine in the forced swimming test.
Topics: Adrenergic alpha-Antagonists; Animals; Buspirone; Depression; Desipramine; Dioxanes; Hydroxydopamine | 1990 |
The role of the mesolimbic dopaminergic system in the desipramine effect in the forced swimming test.
Topics: Animals; Depression; Desipramine; Dopamine; Fluphenazine; Hydroxydopamines; Injections; Limbic Syste | 1990 |