ketanserin has been researched along with Depression in 13 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with ketanserine resulted in an antidepressant-like effect in prenatally stressed OVX females in the FST as compared to the control group." | 5.42 | [Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats]. ( Akulova, VK; Fedotova, IuO; Ordian, NÉ; Pivina, SG, 2015) |
| "Depression is a widespread and devastating mental illness and the search for rapid-acting antidepressants remains critical." | 1.62 | Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice. ( Cole, AB; Hesselgrave, N; Thompson, SM; Troppoli, TA; Wulff, AB, 2021) |
| "Treatment with ketanserine resulted in an antidepressant-like effect in prenatally stressed OVX females in the FST as compared to the control group." | 1.42 | [Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats]. ( Akulova, VK; Fedotova, IuO; Ordian, NÉ; Pivina, SG, 2015) |
| "The present work was devoted to the comparative analysis of influence of chronic administration of 5-HT(2B/2C) receptors agonist - m-CPP (0,5 mg/kg, i." | 1.38 | [Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats]. ( Fedotova, IuO; Frolova, HO; Ordian, NE; Soboliev, VI, 2012) |
| "Comparative study of the effects of chronic administration of 5-HT(2A/2C)-receptors agonist (m-CPP, 0." | 1.38 | [Behavioral effects of ketanserine in prenatally stressed female rats]. ( Fedotova, IuO; Ordian, NE; Pivina, SG, 2012) |
| "The aim of the present work was an estimation of influence of chronic administration of 5-receptors antagonist--NAN-190 (0." | 1.36 | [Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle]. ( Fedotova, IuO, 2010) |
| "A comparative analysis of the influence of chronic administration of the 5-HT2B/2C receptor agonist, m-CPP (0." | 1.36 | [Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats]. ( Fedotova, IuO, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Hesselgrave, N | 1 |
| Troppoli, TA | 1 |
| Wulff, AB | 1 |
| Cole, AB | 1 |
| Thompson, SM | 1 |
| Botanas, CJ | 1 |
| Bryan de la Peña, J | 1 |
| Custodio, RJ | 1 |
| Joy Dela Peña, I | 1 |
| Kim, M | 1 |
| Woo, T | 1 |
| Kim, HJ | 1 |
| Kim, HI | 1 |
| Chang Cho, M | 1 |
| Lee, YS | 1 |
| Cheong, JH | 1 |
| Fedotova, IuO | 5 |
| Ordian, NE | 3 |
| Frolova, HO | 1 |
| Soboliev, VI | 1 |
| Soloff, PH | 2 |
| Chiappetta, L | 1 |
| Mason, NS | 1 |
| Becker, C | 1 |
| Price, JC | 2 |
| Pivina, SG | 2 |
| Akulova, VK | 1 |
| Freitas, AE | 1 |
| Budni, J | 1 |
| Lobato, KR | 1 |
| Binfaré, RW | 1 |
| Machado, DG | 1 |
| Jacinto, J | 1 |
| Veronezi, PO | 1 |
| Pizzolatti, MG | 1 |
| Rodrigues, AL | 1 |
| Meltzer, CC | 1 |
| Fabio, A | 1 |
| Frank, GK | 1 |
| Kaye, WH | 1 |
| Anthony, M | 1 |
| Papp, M | 1 |
| Klimek, V | 1 |
| Willner, P | 1 |
| Onodera, T | 1 |
| Watanabe, R | 1 |
| Tha, KK | 1 |
| Hayashi, Y | 1 |
| Murayama, T | 1 |
| Okuma, Y | 1 |
| Ono, C | 1 |
| Oketani, Y | 1 |
| Hosokawa, M | 1 |
| Nomura, Y | 1 |
1 review available for ketanserin and Depression
| Article | Year |
|---|---|
Serotonin antagonists.
Topics: Cyproheptadine; Depression; Ergotamine; Humans; Hypertension; Ketanserin; Lisuride; Methysergide; Mi | 1984 |
12 other studies available for ketanserin and Depression
| Article | Year |
|---|---|
Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice.
Topics: Animals; Depression; Drug Evaluation, Preclinical; Hallucinogens; Hippocampus; Ketanserin; Male; Mic | 2021 |
Methoxetamine produces rapid and sustained antidepressant effects probably via glutamatergic and serotonergic mechanisms.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanones; Cyclohexylamines; Depression; Keta | 2017 |
[Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats].
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Depression; Estrogens; Estrus; Fema | 2012 |
Effects of serotonin-2A receptor binding and gender on personality traits and suicidal behavior in borderline personality disorder.
Topics: Adult; Aggression; Borderline Personality Disorder; Contrast Media; Depression; Female; Fluorodeoxyg | 2014 |
[Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats].
Topics: Animals; Behavior, Animal; Depression; Drug Administration Schedule; Drug Therapy, Combination; Estr | 2015 |
Antidepressant-like action of the ethanolic extract from Tabebuia avellanedae in mice: evidence for the involvement of the monoaminergic system.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antidepressive Agents; Biogenic Monoami | 2010 |
[Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle].
Topics: Animals; Anxiety; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Estrous Cycle; Fem | 2010 |
[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Depression; E | 2010 |
[Behavioral effects of ketanserine in prenatally stressed female rats].
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Female; | 2012 |
5HT2A receptor binding is increased in borderline personality disorder.
Topics: Adult; Aggression; Borderline Personality Disorder; Brain; Child; Child Abuse; Depression; Female; F | 2007 |
Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Dihydroalprenolol; Im | 1994 |
Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence accelerated mouse (SAM)-P10.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Behavior, Animal; Benzazepines; Brain; Depre | 2000 |