Page last updated: 2024-10-29

ketanserin and Depression

ketanserin has been researched along with Depression in 13 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"Treatment with ketanserine resulted in an antidepressant-like effect in prenatally stressed OVX females in the FST as compared to the control group."5.42[Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats]. ( Akulova, VK; Fedotova, IuO; Ordian, NÉ; Pivina, SG, 2015)
"Depression is a widespread and devastating mental illness and the search for rapid-acting antidepressants remains critical."1.62Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice. ( Cole, AB; Hesselgrave, N; Thompson, SM; Troppoli, TA; Wulff, AB, 2021)
"Treatment with ketanserine resulted in an antidepressant-like effect in prenatally stressed OVX females in the FST as compared to the control group."1.42[Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats]. ( Akulova, VK; Fedotova, IuO; Ordian, NÉ; Pivina, SG, 2015)
"The present work was devoted to the comparative analysis of influence of chronic administration of 5-HT(2B/2C) receptors agonist - m-CPP (0,5 mg/kg, i."1.38[Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats]. ( Fedotova, IuO; Frolova, HO; Ordian, NE; Soboliev, VI, 2012)
"Comparative study of the effects of chronic administration of 5-HT(2A/2C)-receptors agonist (m-CPP, 0."1.38[Behavioral effects of ketanserine in prenatally stressed female rats]. ( Fedotova, IuO; Ordian, NE; Pivina, SG, 2012)
"The aim of the present work was an estimation of influence of chronic administration of 5-receptors antagonist--NAN-190 (0."1.36[Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle]. ( Fedotova, IuO, 2010)
"A comparative analysis of the influence of chronic administration of the 5-HT2B/2C receptor agonist, m-CPP (0."1.36[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats]. ( Fedotova, IuO, 2010)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Hesselgrave, N1
Troppoli, TA1
Wulff, AB1
Cole, AB1
Thompson, SM1
Botanas, CJ1
Bryan de la Peña, J1
Custodio, RJ1
Joy Dela Peña, I1
Kim, M1
Woo, T1
Kim, HJ1
Kim, HI1
Chang Cho, M1
Lee, YS1
Cheong, JH1
Fedotova, IuO5
Ordian, NE3
Frolova, HO1
Soboliev, VI1
Soloff, PH2
Chiappetta, L1
Mason, NS1
Becker, C1
Price, JC2
Pivina, SG2
Akulova, VK1
Freitas, AE1
Budni, J1
Lobato, KR1
Binfaré, RW1
Machado, DG1
Jacinto, J1
Veronezi, PO1
Pizzolatti, MG1
Rodrigues, AL1
Meltzer, CC1
Fabio, A1
Frank, GK1
Kaye, WH1
Anthony, M1
Papp, M1
Klimek, V1
Willner, P1
Onodera, T1
Watanabe, R1
Tha, KK1
Hayashi, Y1
Murayama, T1
Okuma, Y1
Ono, C1
Oketani, Y1
Hosokawa, M1
Nomura, Y1

Reviews

1 review available for ketanserin and Depression

ArticleYear
Serotonin antagonists.
    Australian and New Zealand journal of medicine, 1984, Volume: 14, Issue:6

    Topics: Cyproheptadine; Depression; Ergotamine; Humans; Hypertension; Ketanserin; Lisuride; Methysergide; Mi

1984

Other Studies

12 other studies available for ketanserin and Depression

ArticleYear
Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 04-27, Volume: 118, Issue:17

    Topics: Animals; Depression; Drug Evaluation, Preclinical; Hallucinogens; Hippocampus; Ketanserin; Male; Mic

2021
Methoxetamine produces rapid and sustained antidepressant effects probably via glutamatergic and serotonergic mechanisms.
    Neuropharmacology, 2017, Volume: 126

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanones; Cyclohexylamines; Depression; Keta

2017
[Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2012, Volume: 58, Issue:6

    Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Depression; Estrogens; Estrus; Fema

2012
Effects of serotonin-2A receptor binding and gender on personality traits and suicidal behavior in borderline personality disorder.
    Psychiatry research, 2014, Jun-30, Volume: 222, Issue:3

    Topics: Adult; Aggression; Borderline Personality Disorder; Contrast Media; Depression; Female; Fluorodeoxyg

2014
[Pecularities for action of combined administration of NAN-190 and ketanserine with low dose of 17β-estradiol on depression-like behavior in prenatally stressed ovariectomized rats].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2015, Volume: 101, Issue:1

    Topics: Animals; Behavior, Animal; Depression; Drug Administration Schedule; Drug Therapy, Combination; Estr

2015
Antidepressant-like action of the ethanolic extract from Tabebuia avellanedae in mice: evidence for the involvement of the monoaminergic system.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Mar-17, Volume: 34, Issue:2

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antidepressive Agents; Biogenic Monoami

2010
[Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2010, Volume: 96, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Estrous Cycle; Fem

2010
[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:11

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Depression; E

2010
[Behavioral effects of ketanserine in prenatally stressed female rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Female;

2012
5HT2A receptor binding is increased in borderline personality disorder.
    Biological psychiatry, 2007, Sep-15, Volume: 62, Issue:6

    Topics: Adult; Aggression; Borderline Personality Disorder; Brain; Child; Child Abuse; Depression; Female; F

2007
Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression.
    Psychopharmacology, 1994, Volume: 114, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Dihydroalprenolol; Im

1994
Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence accelerated mouse (SAM)-P10.
    Japanese journal of pharmacology, 2000, Volume: 83, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Behavior, Animal; Benzazepines; Brain; Depre

2000