cyproheptadine has been researched along with Depression in 13 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyproheptadine prevention of the neuropsychiatric adverse effects of an antiretroviral regimen including efavirenz has been evaluated in a randomized clinical trial." | 2.78 | Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial. ( Akhondzadeh, S; Alimadadi, A; Dabaghzadeh, F; Ghaeli, P; Jafari, S; Khalili, H; Khazaeipour, Z, 2013) |
| "Treatment with metyrapone or o,p'-DDD can always induce a clinical remission but not a cure, and neurotransmitter therapy may be effective in a minority of cases." | 2.37 | Cushing's syndrome. ( Besser, GM; Howlett, TA; Rees, LH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dabaghzadeh, F | 1 |
| Ghaeli, P | 1 |
| Khalili, H | 1 |
| Alimadadi, A | 1 |
| Jafari, S | 1 |
| Akhondzadeh, S | 1 |
| Khazaeipour, Z | 1 |
| Yi, LT | 1 |
| Xu, HL | 1 |
| Feng, J | 1 |
| Zhan, X | 1 |
| Zhou, LP | 1 |
| Cui, CC | 1 |
| Fidan, V | 1 |
| Fidan, T | 1 |
| Anthony, M | 1 |
| Sachar, EJ | 1 |
| Nathan, RS | 1 |
| Asnis, G | 1 |
| Halbreich, U | 1 |
| Tabrizi, MA | 1 |
| Halpern, F | 1 |
| Eckert, ED | 1 |
| Goldberg, SC | 1 |
| Halmi, KA | 2 |
| Casper, RC | 1 |
| Davis, JM | 2 |
| Woodrum, ST | 1 |
| Brown, CS | 1 |
| Srivastava, SK | 1 |
| Nath, C | 1 |
| Kähling, J | 1 |
| Ziegler, H | 1 |
| Ballhause, H | 1 |
| Dekirmenjian, H | 1 |
| Casper, R | 1 |
| Goldberg, S | 1 |
| Howlett, TA | 1 |
| Rees, LH | 1 |
| Besser, GM | 1 |
| Itil, TM | 1 |
| Baltes, BJ | 1 |
| Diamond, S | 1 |
3 reviews available for cyproheptadine and Depression
| Article | Year |
|---|---|
Serotonin antagonists.
Topics: Cyproheptadine; Depression; Ergotamine; Humans; Hypertension; Ketanserin; Lisuride; Methysergide; Mi | 1984 |
Management of SSRI-induced sexual dysfunction.
Topics: Adrenergic alpha-Antagonists; Antidepressive Agents, Second-Generation; Cyproheptadine; Depression; | 1998 |
Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoho | 1985 |
2 trials available for cyproheptadine and Depression
| Article | Year |
|---|---|
Cyproheptadine for prevention of neuropsychiatric adverse effects of efavirenz: a randomized clinical trial.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System Diseases; Cyclopropanes; Cypro | 2013 |
Quantitative pharmaco-electroencephalography in the discovery of a new group of psychotropic drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clinical Trials as Topic; Cyproheptadine; Depression; | 1972 |
8 other studies available for cyproheptadine and Depression
| Article | Year |
|---|---|
Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin.
Topics: Adrenergic Antagonists; Animals; Antidepressive Agents; Benzazepines; Cyproheptadine; Depression; Di | 2011 |
Fixed drug eruption against rupatadine fumarate.
Topics: Adolescent; Antipruritics; Cyproheptadine; Depression; Drug Eruptions; Female; Humans | 2011 |
Neuroendocrine studies of major depressive disorder.
Topics: Adult; Blood Glucose; Circadian Rhythm; Corticotropin-Releasing Hormone; Cyproheptadine; Depression; | 1980 |
Depression in anorexia nervosa.
Topics: Anorexia Nervosa; Attitude; Behavior Therapy; Body Weight; Cyproheptadine; Depression; Female; Human | 1982 |
The differential effects of calcium channel blockers in the behavioural despair test in mice.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; D | 2000 |
[Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity].
Topics: Aggression; Animals; Anthracenes; Anxiety; Appetite; Arousal; Behavior, Animal; Body Temperature; Ca | 1975 |
Catecholamine metabolism in anorexia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Blood Pressure; Body Weight; Child; Creatinine; Cyproheptadine; | 1978 |
Experience in a headache clinic within the 'ghetto'.
Topics: Amitriptyline; Anxiety; Community Health Services; Cyproheptadine; Depression; Emotions; Ergotamine; | 1972 |