Page last updated: 2024-08-24

milnacipran and Depression

milnacipran has been researched along with Depression in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's15 (53.57)29.6817
2010's10 (35.71)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Ikenouchi, A; Okamoto, N; Yoshimura, R1
Hirose, E; Isoda, H; Ito, N; Nagai, T; Odaguchi, H; Sasaki, K1
Ishibashi, T; Kawai, H; Kawashima, Y; Kudo, N; Machida, M; Mitsumoto, A1
Ang, DC; Gracely, RH; Hilligoss, J; Jensen, MP; Saha, C; Steiner, JL1
Assié, MB; Auclair, AL; Bardin, L; Cussac, D; Depoortère, R; Heusler, P; Marien, M; Martel, JC; Newman-Tancredi, A; O'Connor, JA1
Albrecht, KL; Bernstein, CD; Marcus, DA1
Abe, M; Mori, Y; Nakata, S; Ochi, S; Ueno, S; Yamazaki, K; Yoshino, Y1
Chen, C; Gommoll, C; McIntyre, RS; Ruth, A1
Koshiishi, T; Okuyama, K1
Isaac, MT1
Hanawa, T; Ito, N; Nagai, T; Oikawa, T; Yabe, T; Yamada, H1
Doe, N; Kiriyama, M; Takahashi, T1
Chou, SY; Hung, TH; Su, JA; Tsai, CS; Tsang, HY; Wu, CL1
Ito, M; Kimura, H; Kurita, K; Nagashima, W; Ozaki, N; Tokura, T; Yoshida, K1
Bouvard, M; Rénéric, JP; Stinus, L1
Higuchi, H; Shimizu, T; Takahashi, H; Yoshida, K1
Endo, S; Kanetani, K; Kimura, M1
Bogolepova, AN; Gekht, AB; Gudkova, AA; Sorokina, IB1
Arita, S; Morishita, S3
Higuchi, H; Kamata, M; Shimizu, T; Takahashi, H; Yoshida, K1
Asada, T; Ohta, H; Satoh, S; Sawa, S; Yamakawa, Y1
Asada, T; Mizukami, K; Tanaka, Y1
Higuchi, H; Inoue, K; Itoh, K; Kamata, M; Ozaki, N; Suzuki, T; Takahashi, H; Yoshida, K1
Higuchi, H; Ozaki, N; Yoshida, K1
Bolotov, AV; Izvozchikov, SB; Kaprin, AD; Selitskiĭ, GV; Troshina, AV1
Autret-Leca, E; Bourgade, B; Ferquel, D; Jonville-Béra, AP; Le Garé, C1

Reviews

2 review(s) available for milnacipran and Depression

ArticleYear
Milnacipran for fibromyalgia: a useful addition to the treatment armamentarium.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Cyclopropanes; Depression; Fatigue; Fibromyalgia; Humans; Milnacipran; Pain Management; Selective Serotonin Reuptake Inhibitors; Weight Loss

2013
Treating depression with SNRIs: who will benefit most?
    CNS spectrums, 2008, Volume: 13, Issue:7 Suppl 11

    Topics: Cyclopropanes; Cytochrome P-450 CYP2D6; Depression; Humans; Meta-Analysis as Topic; Methoxyhydroxyphenylglycol; Milnacipran; Pharmacogenetics; Polymorphism, Genetic; Selective Serotonin Reuptake Inhibitors

2008

Trials

6 trial(s) available for milnacipran and Depression

ArticleYear
Combining cognitive-behavioral therapy and milnacipran for fibromyalgia: a feasibility randomized-controlled trial.
    The Clinical journal of pain, 2013, Volume: 29, Issue:9

    Topics: Adolescent; Adult; Aged; Cognitive Behavioral Therapy; Cyclopropanes; Depression; Double-Blind Method; Feasibility Studies; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Outcome Assessment, Health Care; Pain Measurement; Pain Perception; Selective Serotonin Reuptake Inhibitors; Time Factors; Young Adult

2013
Prevention of poststroke depression with milnacipran in patients with acute ischemic stroke: a double-blind randomized placebo-controlled trial.
    International clinical psychopharmacology, 2011, Volume: 26, Issue:5

    Topics: Aged; Cyclopropanes; Depression; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Milnacipran; Stroke; Treatment Outcome

2011
Differential effects of fluvoxamine, paroxetine and milnacipran for depression, especially with regard to age.
    Human psychopharmacology, 2004, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Chi-Square Distribution; Cohort Studies; Cyclopropanes; Depression; Female; Fluvoxamine; Humans; Male; Middle Aged; Milnacipran; Paroxetine; Psychiatric Status Rating Scales; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2004
Efficacy of milnacipran on poststroke depression on inpatient rehabilitation.
    Psychiatry and clinical neurosciences, 2005, Volume: 59, Issue:6

    Topics: Activities of Daily Living; Affect; Aged; Antidepressive Agents; Cyclopropanes; Depression; Female; Humans; Male; Middle Aged; Milnacipran; Psychiatric Status Rating Scales; Quality of Life; Stroke; Stroke Rehabilitation; Surveys and Questionnaires; Treatment Outcome

2005
Efficacy of milnacipran on the depressive state in patients with Alzheimer's disease.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Sep-30, Volume: 30, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cyclopropanes; Depression; Female; Humans; Male; Middle Aged; Milnacipran; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome

2006
The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine.
    Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:6

    Topics: Adult; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclopropanes; Depression; Exons; Female; Fluvoxamine; Gene Frequency; Genotype; Humans; Male; Middle Aged; Milnacipran; Patient Compliance; Patient Selection; Phenotype; Polymorphism, Genetic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Time Factors; Treatment Outcome

2007

Other Studies

20 other study(ies) available for milnacipran and Depression

ArticleYear
Effect of Milnacipran on Plasma Level of Vascular Endothelial Growth Factor in Major Depression.
    Psychopharmacology bulletin, 2022, 10-27, Volume: 52, Issue:4

    Topics: Antidepressive Agents; Cyclopropanes; Depression; Depressive Disorder, Major; Humans; Milnacipran; Selective Serotonin Reuptake Inhibitors; Vascular Endothelial Growth Factor A

2022
Preventive effect of a Kampo medicine, kososan, on recurrent depression in a mouse model of repeated social defeat stress.
    Gene, 2022, Jan-05, Volume: 806

    Topics: Administration, Oral; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Hippocampus; Japan; Male; Medicine, Kampo; Mice; Mice, Inbred BALB C; Milnacipran; Molecular Sequence Annotation; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Recurrence; Social Defeat; Stress, Psychological

2022
Chronopharmacological Analysis of Antidepressant Activity of a Dual-Action Serotonin Noradrenaline Reuptake Inhibitor (SNRI), Milnacipran, in Rats.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:2

    Topics: Administration, Oral; Adrenergic Neurons; Animals; Antidepressive Agents; Behavior, Animal; Brain; Chronopharmacokinetics; Circadian Rhythm; Cyclopropanes; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Hippocampus; Male; Milnacipran; Norepinephrine; Rats; Rats, Wistar; Serotonergic Neurons; Serotonin and Noradrenaline Reuptake Inhibitors; Tissue Distribution

2018
Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety.
    Neuropharmacology, 2013, Volume: 70

    Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cerebral Cortex; Cyclohexanols; Cyclopropanes; Depression; Dopamine; Duloxetine Hydrochloride; Humans; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Transport Proteins; Norepinephrine; Rats; Serotonin; Synaptosomes; Thiophenes; Venlafaxine Hydrochloride

2013
Antidepressant action via the nitric oxide system: A pilot study in an acute depressive model induced by arginin.
    Neuroscience letters, 2015, Jul-10, Volume: 599

    Topics: Acute Disease; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Arginine; Cyclopropanes; Depression; Fluoxetine; Male; Mianserin; Milnacipran; Mirtazapine; Nitric Oxide; Nitric Oxide Synthase; Pilot Projects; Rats, Wistar; Selective Serotonin Reuptake Inhibitors

2015
The efficacy of levomilnacipran ER across symptoms of major depressive disorder: a post hoc analysis of 5 randomized, double-blind, placebo-controlled trials.
    CNS spectrums, 2016, Volume: 21, Issue:5

    Topics: Adult; Anhedonia; Anorexia; Antidepressive Agents; Clinical Trials, Phase III as Topic; Cyclopropanes; Delayed-Action Preparations; Depression; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Milnacipran; Randomized Controlled Trials as Topic; Suicidal Ideation; Treatment Outcome

2016
Probable Serotonin Syndrome and Withdrawal Symptoms Caused by Milnacipran.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2016, Volume: 136, Issue:12

    Topics: Aged; Antidepressive Agents; Cerebral Hemorrhage; Cyclopropanes; Depression; Drug Substitution; Female; Humans; Mianserin; Milnacipran; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Substance Withdrawal Syndrome; Treatment Outcome

2016
A possible mechanism underlying an antidepressive-like effect of Kososan, a Kampo medicine, via the hypothalamic orexinergic system in the stress-induced depression-like model mice.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:10

    Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cyclopropanes; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hippocampus; Hypothalamus; Intracellular Signaling Peptides and Proteins; Magnoliopsida; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Milnacipran; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Orexins; Phytotherapy; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological

2009
Behavioral despair during a water maze learning task in mice.
    Experimental animals, 2010, Volume: 59, Issue:2

    Topics: Animals; Behavior, Animal; Cyclopropanes; Depression; Disease Models, Animal; Escape Reaction; Fluvoxamine; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Milnacipran; Selective Serotonin Reuptake Inhibitors; Swimming

2010
Plasma levels of milnacipran and its effectiveness for the treatment of chronic pain in the orofacial region.
    Human psychopharmacology, 2012, Volume: 27, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Chronic Pain; Cyclopropanes; Depression; Dose-Response Relationship, Drug; Facial Pain; Female; Humans; Male; Middle Aged; Milnacipran; Pain Measurement; Retrospective Studies; Statistics as Topic; Young Adult

2012
In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs.
    Behavioural brain research, 2002, Nov-15, Volume: 136, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Clonidine; Cyclopropanes; Depression; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Male; Mianserin; Milnacipran; Mirtazapine; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Swimming

2002
Favorable effect of milnacipran on depression induced by interferon-alpha.
    The Journal of neuropsychiatry and clinical neurosciences, 2003,Spring, Volume: 15, Issue:2

    Topics: Aged; Cyclopropanes; Depression; Dose-Response Relationship, Drug; Humans; Interferon alpha-2; Interferon-alpha; Male; Milnacipran; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors

2003
Therapeutic effects of milnacipran (serotonin noradrenalin reuptake inhibitor) on depression following mild and moderate traumatic brain injury.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2003, Volume: 70, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents; Brain Injuries; Cyclopropanes; Depression; Drug Evaluation; Female; Humans; Male; Middle Aged; Milnacipran; Selective Serotonin Reuptake Inhibitors

2003
[Experience with ixel (milnacipran hydrochloride) use in the treatment of patients with post-stroke depression].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:10

    Topics: Adult; Aged; Antidepressive Agents; Case-Control Studies; Cyclopropanes; Depression; Female; Humans; Male; Middle Aged; Milnacipran; Severity of Illness Index; Stroke; Treatment Outcome

2003
Prevalence of induced mania in patients treated with milnacipran: a comparison with paroxetine.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:5

    Topics: Adult; Aged; Bipolar Disorder; Cohort Studies; Cyclopropanes; Depression; Female; Humans; Male; Middle Aged; Milnacipran; Paroxetine; Prevalence; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires

2004
Differential effects of milnacipran, fluvoxamine and paroxetine for inhibited and agitated depression.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:7

    Topics: Cohort Studies; Cyclopropanes; Depression; Drug Administration Schedule; Fluvoxamine; Humans; Milnacipran; Paroxetine; Psychomotor Agitation; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires

2004
Remarkable effect of milnacipran, a serotonin-noradrenalin reuptake inhibitor (SNRI), on depressive symptoms in patients with Parkinson's disease who have insufficient response to selective serotonin reuptake inhibitors (SSRIs): two case reports.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Cyclopropanes; Depression; Female; Humans; Male; Middle Aged; Milnacipran; Parkinson Disease; Selective Serotonin Reuptake Inhibitors

2005
Successful treatment of severe antidepressant-induced nausea with a combination of milnacipran and olanzapine.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:2

    Topics: Adult; Antidepressive Agents; Benzodiazepines; Cyclopropanes; Depression; Drug Therapy, Combination; Female; Humans; Milnacipran; Nausea; Obsessive-Compulsive Disorder; Olanzapine; Selective Serotonin Reuptake Inhibitors

2007
[Milnacipran (ixel) in the treatment of anxiodepressive and sexual disorders in patients with noninflammatory syndrome of chronic pelvic pain].
    Terapevticheskii arkhiv, 2007, Volume: 79, Issue:5

    Topics: Adult; Antidepressive Agents; Anxiety; Cyclopropanes; Depression; Humans; Male; Milnacipran; Pelvic Pain; Sexual Dysfunctions, Psychological; Treatment Outcome

2007
Raynaud's syndrome in a patient treated with milnacipran.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:9

    Topics: Adult; Antidepressive Agents; Cyclopropanes; Depression; Female; Humans; Milnacipran; Raynaud Disease; Selective Serotonin Reuptake Inhibitors

1999