Page last updated: 2024-11-02

oxazepam and Depression

oxazepam has been researched along with Depression in 33 studies

Oxazepam: A benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.
oxazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" Patients were encouraged to regulate their own dosage of oxazepam, and no difficulties occurred with this technique."5.26Oxazepam in the treatment of anxiety associated with depression: results of treatment in 1600 cases (Studies in depression, VI). ( Bailey, HR; Davies, E; Morrison, IJ, 1981)
"Forty-eight patients with anxiety states were treated with oxazepam (Serenid-D), which was administered in tablets of three different colours-red, yellow, and green."5.03Study on the effects of tablet colour in the treatment of anxiety states. ( Griffiths, NR; McClelland, HA; Newell, DJ; Schapira, K, 1970)
"A patient developed severe anxiety, moodswing, depression, and thinking disorder 24 hours after abruptly stopping oxazepam, of which he had taken 30 mg 3 times a day for two months, for anxiety and panic attacks."3.66Abstinence syndrome from therapeutic doses of oxazepam. ( Kulik, AV; Wilbur, R, 1983)
"The progression in severity of withdrawal symptoms (increase in CIWA-Ar above baseline) was also significantly greater in the placebo group (p < 0."2.70Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial. ( Baer, JS; Malte, CA; Reoux, JP; Saxon, AJ; Sloan, KL, 2001)
" Recent research suggests that this is due to metabolic and pharmacokinetic differences rather than an intrinsically more favourable toxic-to-therapeutic dosage ratio."2.64The clinical activity of oxazepam. ( Cardon, A; Fouks, L; Pinalie, B; Porcheron, JB, 1978)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199028 (84.85)18.7374
1990's1 (3.03)18.2507
2000's2 (6.06)29.6817
2010's2 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tvete, IF1
Bjørner, T1
Skomedal, T1
Howland, RH1
SCASSERRA, BB1
Cotroneo, A1
Gareri, P1
Nicoletti, N1
Lacava, R1
Grassone, D1
Maina, E1
De Sarro, G1
Cabodi, S1
Wilbur, R1
Kulik, AV1
Bailey, HR2
Davies, E1
Morrison, IJ1
Bieganowski, L1
Czerwiński, M1
Reoux, JP1
Saxon, AJ1
Malte, CA1
Baer, JS1
Sloan, KL1
Yesavage, J1
Azcarate, CL1
Gmür, M1
Angst, J1
Fouks, L1
Pinalie, B1
Porcheron, JB1
Cardon, A1
Vinar, O1
Dostalová, J1
Krsiak, M1
Reznícek, V1
Ivanys, E1
Laffranchini, S1
Rimón, R1
Kultalahti, ER1
Kalli, A1
Koskinen, T1
Lepola, U1
Naarala, M1
Tick, E1
Väisänen, E1
Jalkanen, E1
Hollister, LE1
Prokudin, VN1
Edelstein, EL1
Isac, M1
Stein, J1
Ladame, FG1
Blackwell, B1
Bobon, J1
Collard, J1
Breulet, M1
Claghorn, J1
Kellner, R1
Hanna, SM1
Harry, TV1
Adler, F1
Reiner, M1
Schapira, K1
McClelland, HA1
Griffiths, NR1
Newell, DJ1
Maccagnani, G1
Ferri, G1
Albonetti, G1
Malm, U1
Thomas, JC1
Selig, JW1
Guthy, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms[NCT00202514]Phase 2/Phase 340 participants Interventional2004-09-30Completed
Prospective Assessment of Valproate on Ethanol Withdrawal[NCT03235531]Phase 4210 participants (Anticipated)Interventional2017-07-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for oxazepam and Depression

ArticleYear
Minor tranquilizers in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Depression; Diazepam; Epilepsy;

1975
[Features of the clinical effect of benzodiazepine derivatives (according to the findings of comparative studies). Review of the literature].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:2

    Topics: Adjustment Disorders; Aggression; Animals; Antisocial Personality Disorder; Barbiturates; Benzazepin

1973

Trials

13 trials available for oxazepam and Depression

ArticleYear
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha

2001
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha

2001
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha

2001
Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Aged; Alcoholism; Anticonvulsants; Anxiety; Depression; Double-Blind Method; Etha

2001
[Combination of phenylpyrrolidinopentane (Katovit) and oxazepam (Adumbran). A double-blind comparison with opipramol (Insidon) in depressive syndromes].
    International pharmacopsychiatry, 1977, Volume: 12, Issue:2

    Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Therapy, Combination; Female;

1977
The clinical activity of oxazepam.
    Acta psychiatrica Scandinavica. Supplementum, 1978, Issue:274

    Topics: Alcoholism; Anxiety Disorders; Clinical Trials as Topic; Depression; Drug Evaluation; Humans; Mental

1978
Controlled comparison of the therapeutic effects of natrium oxybutyrate and oxazepam.
    Activitas nervosa superior, 1979, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Anxiety; Depersonalization; Depression; Double-Blind Method; Humans; Hydrox

1979
[5 years' experience with a new tranquilizer lexotanil (ro 5-3350) in ambulatory patients in a psychiatric practice (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1975, Volume: 32, Issue:11

    Topics: Anxiety; Benzodiazepines; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Depression; Drug

1975
Alprazolam and oxazepam in the treatment of anxious out-patients with depressive symptoms: a double-blind multicenter study.
    Pharmacopsychiatry, 1991, Volume: 24, Issue:3

    Topics: Adult; Alprazolam; Anxiety Disorders; Depression; Double-Blind Method; Humans; Middle Aged; Oxazepam

1991
A double-blind study of alprazolam and oxazepam in the treatment of anxiety.
    Acta psychiatrica Scandinavica, 1987, Volume: 75, Issue:5

    Topics: Adult; Alprazolam; Anxiety Disorders; Depression; Double-Blind Method; Female; Humans; Male; Middle

1987
[Prudent use of drugs against anxiety].
    Der Internist, 1973, Volume: 14, Issue:4

    Topics: Anxiety; Chemical Phenomena; Chemistry; Depression; Diazepam; Evaluation Studies as Topic; Humans; H

1973
How antagonistic can doctor's bias be on drug effect? Oxazepam as an anti-anxiety agent.
    International pharmacopsychiatry, 1973, Volume: 8, Issue:1

    Topics: Anxiety; Anxiety Disorders; Attitude of Health Personnel; Clinical Trials as Topic; Countertransfere

1973
[A comparative ambulatory experiment with Ro 5-3350 (Lexotanil) and oxazepam (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Aug-20, Volume: 63, Issue:33

    Topics: Adolescent; Adult; Aged; Anxiety; Benzodiazepinones; Clinical Trials as Topic; Depression; Drug Eval

1974
When is a tranquillizer an antidepressant?
    Current therapeutic research, clinical and experimental, 1971, Volume: 13, Issue:9

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depression; Dibenzocycloh

1971
[Evaluation of a new tranquilizer, Seresta, in a medical policlinic].
    Praxis, 1966, Dec-08, Volume: 55, Issue:49

    Topics: Aged; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depression; Female; Humans

1966
Study on the effects of tablet colour in the treatment of anxiety states.
    British medical journal, 1970, May-23, Volume: 1, Issue:5707

    Topics: Adult; Analysis of Variance; Anxiety; Color; Depression; Female; Humans; Male; Oxazepam; Phobic Diso

1970

Other Studies

18 other studies available for oxazepam and Depression

ArticleYear
A 5-year follow-up study of users of benzodiazepine: starting with diazepam versus oxazepam.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2016, Volume: 66, Issue:645

    Topics: Adult; Anti-Anxiety Agents; Anxiety; Depression; Diazepam; Dose-Response Relationship, Drug; Drug Pr

2016
Oxazepam for the Treatment of Substance Abuse and Depression: Is it Appropriate?
    Journal of psychosocial nursing and mental health services, 2016, May-01, Volume: 54, Issue:5

    Topics: Depression; Humans; Hypnotics and Sedatives; Oxazepam; Substance-Related Disorders

2016
PLACE OF AN ANTI-ANXIETY AGENT IN GENERAL PRACTICE.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Adolescent; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Child; Depressio

1965
Effectiveness and safety of hypnotic drugs in the treatment of insomnia in over 70-year old people.
    Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1

    Topics: Aged; Cognition Disorders; Dementia; Depression; Drug Administration Schedule; Female; Health Status

2007
Abstinence syndrome from therapeutic doses of oxazepam.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:4

    Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazep

1983
Oxazepam in the treatment of anxiety associated with depression: results of treatment in 1600 cases (Studies in depression, VI).
    Current medical research and opinion, 1981, Volume: 7, Issue:3

    Topics: Adult; Anxiety; Depression; Drug Therapy, Combination; Female; Humans; Male; Oxazepam

1981
[Decompensation of glaucoma after administration of tricyclic antidepressants and anxiolytic drugs].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Sep-22, Volume: 35, Issue:38

    Topics: Amitriptyline; Depression; Female; Glaucoma; Humans; Imipramine; Intraocular Pressure; Middle Aged;

1980
Dementia: differential diagnosis and treatment.
    Geriatrics, 1979, Volume: 34, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Dementia; Depression; Diagnosis, Differential; Dihydroergotoxine;

1979
Studies in depression. II. Treatment of the depressed, frigid woman.
    The Medical journal of Australia, 1973, Apr-28, Volume: 1, Issue:17

    Topics: Adult; Clitoris; Depression; Estradiol; Female; Humans; Oxazepam; Psychotherapy; Sex Education; Sexu

1973
Psychotropic drugs in use today. The role of diazepam in medical practice.
    JAMA, 1973, Sep-24, Volume: 225, Issue:13

    Topics: Anxiety Disorders; Chlordiazepoxide; Depression; Diazepam; Drug Interactions; Drug Utilization; Fami

1973
[Oxazepam or WY 3498, a new muscle-relaxing tranquilizer in ambulatory treatment].
    Acta neurologica et psychiatrica Belgica, 1965, Volume: 65, Issue:5

    Topics: Antidepressive Agents; Anxiety Disorders; Depression; Female; Gastrointestinal Diseases; Humans; Mal

1965
A case of oxazepam (serenid D) dependence.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 120, Issue:557

    Topics: Adult; Anxiety; Depression; Humans; Male; Oxazepam; Phenelzine; Substance Withdrawal Syndrome; Subst

1972
Oxazepam (Serenid D) dependence.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:561

    Topics: Adult; Depression; Humans; Male; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorder

1972
[Preliminary therapeutic results with a new derivative of benzodiazepine: Oxazepam (Rav. 3031)].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1967, Oct-31, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Aged; Anxiety; Child; Depression; Female; Humans; Male; Mental Disorders; Middle

1967
[Oxazepam in alcoholism, depression and anxiety neuroses. A preliminary trial].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1968, Volume: 22, Issue:2

    Topics: Absenteeism; Adolescent; Adult; Aged; Alcoholism; Anxiety Disorders; Depression; Humans; Male; Middl

1968
Clinical evaluation of oxazepam in an out-patient psychiatric clinic.
    Diseases of the nervous system, 1966, Volume: 27, Issue:4

    Topics: Adult; Antidepressive Agents; Anxiety; Depression; Female; Humans; Male; Outpatient Clinics, Hospita

1966
A possible oxazepam abstinence syndrome.
    JAMA, 1966, Nov-21, Volume: 198, Issue:8

    Topics: Adult; Antidepressive Agents; Depression; Female; Humans; Oxazepam; Psychotic Disorders; Substance W

1966
[Experiences with adumbran in a neurologic practice].
    Die Medizinische Welt, 1966, May-14, Volume: 20

    Topics: Depression; Dysautonomia, Familial; Humans; Mental Disorders; Neurotic Disorders; Oxazepam

1966