spermidine has been researched along with Depression in 4 studies
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(R)-Ketamine exhibits rapid and sustained antidepressant effects in animal models of depression." | 3.88 | Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine. ( Hashimoto, K; Shirayama, Y, 2018) |
| "The nature of the side effects produced by the antimalarials and a common moiety present in these drugs (spermidine) links the polyamines to both schizophrenia and depression." | 3.67 | The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression. ( Andrews, RC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shirayama, Y | 1 |
| Hashimoto, K | 1 |
| Pham, TH | 1 |
| Defaix, C | 1 |
| Xu, X | 1 |
| Deng, SX | 1 |
| Fabresse, N | 1 |
| Alvarez, JC | 1 |
| Landry, DW | 1 |
| Brachman, RA | 1 |
| Denny, CA | 1 |
| Gardier, AM | 1 |
| Barth, A | 1 |
| Bilkei-Gorzo, A | 1 |
| Drews, E | 1 |
| Otte, DM | 1 |
| Diaz-Lacava, A | 1 |
| Varadarajulu, J | 1 |
| Turck, CW | 1 |
| Wienker, TF | 1 |
| Zimmer, A | 1 |
| Andrews, RC | 1 |
4 other studies available for spermidine and Depression
| Article | Year |
|---|---|
Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Excitatory | 2018 |
Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Ketamine; Magnetic Resonance Spe | 2018 |
Analysis of quantitative trait loci in mice suggests a role of Enoph1 in stress reactivity.
Topics: Animals; Anxiety; Chromosomes, Mammalian; Depression; Female; Male; Mice; Mice, Inbred C3H; Mice, In | 2014 |
The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression.
Topics: Antimalarials; Depression; Female; Humans; Lupus Erythematosus, Systemic; Menstruation Disturbances; | 1985 |