Page last updated: 2024-11-01

nimesulide and Depression

nimesulide has been researched along with Depression in 4 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
" We describe a case of reversible symptomatic duodenal compression caused by a retroperitoneal hematoma after ingestion of sertraline and nimesulide."3.72Symptomatic reversible duodenal compression due to iatrogenic retroperitoneal hematoma. ( Bassotti, G; de Roberto, G; Fischer, MJ; Morelli, A; Nzepa, FS, 2004)
"Nimesulide treatment (10 mg/kg) prevented the ethanol withdrawal-induced alterations in the levels of TNF-α, IL-1β, and IL-6 in the hippocampus, prefrontal cortex, and striatum."1.72Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice. ( Buss, ZS; Doneda, DL; Fernandes, IL; Fraga-Junior, EB; Lima, E; Rios-Santos, F; Rohden, CAH; Vandresen-Filho, S; Ynoue, HN, 2022)
"Nimesulide is an inhibitor of COX-2 with antioxidant and anti-inflammatory effects."1.56Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide. ( Luo, W; Luo, Y; Yang, J, 2020)
"Pretreatment with indomethacin (10mg/kg; i."1.36Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice. ( Andrade, CA; de Paiva, VN; Fernandes, MM; Giusti-Paiva, A; Lima, SN; Soncini, R, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Fraga-Junior, EB1
Fernandes, IL1
Rohden, CAH1
Doneda, DL1
Ynoue, HN1
Rios-Santos, F1
Lima, E1
Buss, ZS1
Vandresen-Filho, S1
Luo, W1
Luo, Y1
Yang, J1
de Paiva, VN1
Lima, SN1
Fernandes, MM1
Soncini, R1
Andrade, CA1
Giusti-Paiva, A1
Bassotti, G1
Nzepa, FS1
de Roberto, G1
Fischer, MJ1
Morelli, A1

Other Studies

4 other studies available for nimesulide and Depression

ArticleYear
Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice.
    Brain research bulletin, 2022, Volume: 191

    Topics: Alcoholism; Animals; Behavior, Animal; Cytokines; Depression; Ethanol; Hippocampus; Interleukin-6; L

2022
Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide.
    Scientific reports, 2020, 07-06, Volume: 10, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Cyclooxygenase 2 Inhibitors

2020
Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice.
    Behavioural brain research, 2010, Dec-20, Volume: 215, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Depression; Dexamethason

2010
Symptomatic reversible duodenal compression due to iatrogenic retroperitoneal hematoma.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Depression; Drug Interactions; Duodenal Diseases; Female; H

2004