nimesulide has been researched along with Depression in 4 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe a case of reversible symptomatic duodenal compression caused by a retroperitoneal hematoma after ingestion of sertraline and nimesulide." | 3.72 | Symptomatic reversible duodenal compression due to iatrogenic retroperitoneal hematoma. ( Bassotti, G; de Roberto, G; Fischer, MJ; Morelli, A; Nzepa, FS, 2004) |
| "Nimesulide treatment (10 mg/kg) prevented the ethanol withdrawal-induced alterations in the levels of TNF-α, IL-1β, and IL-6 in the hippocampus, prefrontal cortex, and striatum." | 1.72 | Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice. ( Buss, ZS; Doneda, DL; Fernandes, IL; Fraga-Junior, EB; Lima, E; Rios-Santos, F; Rohden, CAH; Vandresen-Filho, S; Ynoue, HN, 2022) |
| "Nimesulide is an inhibitor of COX-2 with antioxidant and anti-inflammatory effects." | 1.56 | Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide. ( Luo, W; Luo, Y; Yang, J, 2020) |
| "Pretreatment with indomethacin (10mg/kg; i." | 1.36 | Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice. ( Andrade, CA; de Paiva, VN; Fernandes, MM; Giusti-Paiva, A; Lima, SN; Soncini, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fraga-Junior, EB | 1 |
| Fernandes, IL | 1 |
| Rohden, CAH | 1 |
| Doneda, DL | 1 |
| Ynoue, HN | 1 |
| Rios-Santos, F | 1 |
| Lima, E | 1 |
| Buss, ZS | 1 |
| Vandresen-Filho, S | 1 |
| Luo, W | 1 |
| Luo, Y | 1 |
| Yang, J | 1 |
| de Paiva, VN | 1 |
| Lima, SN | 1 |
| Fernandes, MM | 1 |
| Soncini, R | 1 |
| Andrade, CA | 1 |
| Giusti-Paiva, A | 1 |
| Bassotti, G | 1 |
| Nzepa, FS | 1 |
| de Roberto, G | 1 |
| Fischer, MJ | 1 |
| Morelli, A | 1 |
4 other studies available for nimesulide and Depression
| Article | Year |
|---|---|
Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice.
Topics: Alcoholism; Animals; Behavior, Animal; Cytokines; Depression; Ethanol; Hippocampus; Interleukin-6; L | 2022 |
Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of nimesulide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Cyclooxygenase 2 Inhibitors | 2020 |
Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Depression; Dexamethason | 2010 |
Symptomatic reversible duodenal compression due to iatrogenic retroperitoneal hematoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Depression; Drug Interactions; Duodenal Diseases; Female; H | 2004 |