Page last updated: 2024-10-25

cyclobenzaprine and Depression

cyclobenzaprine has been researched along with Depression in 4 studies

cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"We attempted a randomized, double blind trial of placebo vs cyclobenzaprine (Flexeril) in 40 female patients with fibromyalgia from a private rheumatology practice in Maine."9.06A randomized trial of cyclobenzaprine for the treatment of fibromyalgia. ( Block, SR; Gratwick, GM; Quimby, LG; Whitney, CD, 1989)
"We attempted a randomized, double blind trial of placebo vs cyclobenzaprine (Flexeril) in 40 female patients with fibromyalgia from a private rheumatology practice in Maine."5.06A randomized trial of cyclobenzaprine for the treatment of fibromyalgia. ( Block, SR; Gratwick, GM; Quimby, LG; Whitney, CD, 1989)
" Pharmacokinetic parameters related to absorption, distribution, and elimination were calculated."2.78Pharmacokinetics and bioequivalence evaluation of cyclobenzaprine tablets. ( Brioschi, TM; Ching, TH; Kano, EK; Koono, EE; Porta, V; Schramm, SG; Serra, CH, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brioschi, TM1
Schramm, SG1
Kano, EK1
Koono, EE1
Ching, TH1
Serra, CH1
Porta, V1
Scanlon, KA1
Stoppacher, R1
Blum, LM1
Starkey, SJ1
O'Neil, BA1
Knudson, GA1
Bhaskara, SM1
Quimby, LG1
Gratwick, GM1
Whitney, CD1
Block, SR1

Trials

2 trials available for cyclobenzaprine and Depression

ArticleYear
Pharmacokinetics and bioequivalence evaluation of cyclobenzaprine tablets.
    BioMed research international, 2013, Volume: 2013

    Topics: Amitriptyline; Antidepressive Agents; Chromatography, High Pressure Liquid; Depression; Half-Life; H

2013
A randomized trial of cyclobenzaprine for the treatment of fibromyalgia.
    The Journal of rheumatology. Supplement, 1989, Volume: 19

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Fibromyalgia; Humans; Midd

1989

Other Studies

2 other studies available for cyclobenzaprine and Depression

ArticleYear
Comprehensive Duloxetine Analysis in a Fatal Overdose.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:2

    Topics: Aged; Alcoholism; Amitriptyline; Depression; Diphenhydramine; Drug Overdose; Duloxetine Hydrochlorid

2016
First episode psychosis following cyclobenzaprine use.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2000, Volume: 45, Issue:8

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Psychoses, Subst

2000