amoxapine has been researched along with Depression in 33 studies
Amoxapine: The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
amoxapine : A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amoxapine (Demolox; Lederle), an antidepressive agent, was administered to 24 patients suffering from pathological depression in an open uncontrolled single-blind study." | 9.05 | Amoxapine in the treatment of depression. A clinical evaluation in ambulant patients. ( Louw, DA; van Wyk, EM, 1982) |
| "We report a case of serotonin syndrome in a patient being treated with paroxetine for depression." | 7.72 | [Case of prolonged recovery from serotonin syndrome caused by paroxetine]. ( Katsu, H; Nakayama, K; Ochiai, Y; Okino, S; Wakutsu, N, 2003) |
| "Amitriptyline was the most effective with regard to symptoms included in the factor Sleep Disturbances and-secondary maybe-towards some items included in the factor Somatization." | 6.65 | Amoxapine versus amitriptyline in endogenous depression. A double-blind study. ( Fruensgaard, K; Hansen, CE; Korsgaard, S; Nymgaard, K; Vaag, UH, 1979) |
| "We report a case of serotonin syndrome in a patient being treated with paroxetine for depression." | 3.72 | [Case of prolonged recovery from serotonin syndrome caused by paroxetine]. ( Katsu, H; Nakayama, K; Ochiai, Y; Okino, S; Wakutsu, N, 2003) |
| "Although a 76-year-old woman with a diagnosis of depression began a course of maprotiline, the drug was discontinued after 14 days when she developed a rash." | 3.70 | [A case of allergic cross reaction between tricyclic antidepressants and maprotiline]. ( Kodama, Y; Nomura, S; Shimizu, K; Watanabe, M, 1998) |
| "We present a case of successful treatment of a patient with depression who showed remarkable improvement with a high-dose treatment of amoxapine." | 3.70 | [Successful treatment using high-dose amoxapine for a depressive patient]. ( Kuwahara, T; Nomura, S; Sanga, M; Shigemura, J, 1999) |
| "A young woman developed galactorrhea during treatment with a new dibenzoxazepine antidepressant, amoxapine." | 3.66 | Single case study. Amoxapine, a new antidepressant, appears in human milk. ( Gelenberg, AJ, 1979) |
| "Amoxapine was inferior to imipramine as an inhibitor of 5-HT uptake, also in vitro." | 2.65 | Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression. ( Ahlfors, UG; Tukiainen, E; Tuomisto, J, 1979) |
| "Amoxapine was superior to imipramine in terms of safety and usefulness." | 2.65 | Comparison of efficacy of amoxapine and imipramine in a multi-clinic double-blind study using the WHO schedule for a standard assessment of patients with depressive disorders. ( Hara, T; Kazamatsuri, H; Kurita, H; Kurokawa, H; Mori, A; Murasaki, M; Oguchi, T; Saito, Y; Sakuma, A; Sakurai, Y; Takahashi, R; Takemura, M; Yuzuriha, T, 1979) |
| "Amitriptyline was the most effective with regard to symptoms included in the factor Sleep Disturbances and-secondary maybe-towards some items included in the factor Somatization." | 2.65 | Amoxapine versus amitriptyline in endogenous depression. A double-blind study. ( Fruensgaard, K; Hansen, CE; Korsgaard, S; Nymgaard, K; Vaag, UH, 1979) |
| " Both drugs were given in a dosage of 25 mg 3-times daily over a period of 4 weeks, and patients' progress was assessed using psychiatric and psychological rating scales for depression." | 2.65 | Amoxapine in depressive illness. ( Holden, JM; Kerry, RJ; Orme, JE, 1979) |
| "Acute renal failure, a brief seizure, and mild rhabdomyolysis developed in a 27-year-old man following overdosage with the tricyclic antidepressant, amoxapine." | 1.27 | Amoxapine-associated acute renal failure. ( Harrington, JT; Jennings, AE; Levey, AS, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (72.73) | 18.7374 |
| 1990's | 5 (15.15) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, T | 1 |
| Washiyama, K | 1 |
| Ikeda, K | 1 |
| Ochiai, Y | 1 |
| Katsu, H | 1 |
| Okino, S | 1 |
| Wakutsu, N | 1 |
| Nakayama, K | 1 |
| Lydiard, RB | 1 |
| Pottash, AL | 1 |
| Gold, MS | 1 |
| Kane, JM | 1 |
| Lieberman, J | 1 |
| McNair, DM | 2 |
| Kahn, RJ | 2 |
| Frankenthaler, LM | 2 |
| Faldetta, LL | 2 |
| Gever, LN | 1 |
| Abbott, R | 1 |
| Jennings, AE | 1 |
| Levey, AS | 1 |
| Harrington, JT | 1 |
| Kimball, DF | 1 |
| Lampert, AA | 1 |
| Burrows, GD | 1 |
| Norman, TR | 1 |
| Davies, BM | 1 |
| van Wyk, EM | 1 |
| Louw, DA | 1 |
| Shader, RI | 1 |
| Greenblatt, DJ | 1 |
| Kaumeier, HS | 1 |
| Haase, HJ | 1 |
| Boutelle, WE | 1 |
| Shima, S | 1 |
| Loche, F | 1 |
| Durieu, C | 1 |
| Bazex, J | 1 |
| Shimizu, K | 1 |
| Watanabe, M | 1 |
| Kodama, Y | 1 |
| Nomura, S | 2 |
| Sakamoto, A | 1 |
| Hoshino, T | 1 |
| Suzuki, H | 1 |
| Kimura, M | 1 |
| Ogawa, R | 1 |
| Shigemura, J | 1 |
| Kuwahara, T | 1 |
| Sanga, M | 1 |
| Nisijima, K | 1 |
| Takamori, K | 1 |
| Yoshida, S | 1 |
| Okuyama, S | 1 |
| Tuomisto, J | 1 |
| Tukiainen, E | 1 |
| Ahlfors, UG | 1 |
| Takahashi, R | 1 |
| Sakuma, A | 1 |
| Hara, T | 1 |
| Kazamatsuri, H | 1 |
| Mori, A | 1 |
| Saito, Y | 1 |
| Murasaki, M | 2 |
| Oguchi, T | 1 |
| Sakurai, Y | 1 |
| Yuzuriha, T | 1 |
| Takemura, M | 1 |
| Kurokawa, H | 1 |
| Kurita, H | 1 |
| Fruensgaard, K | 1 |
| Hansen, CE | 1 |
| Korsgaard, S | 1 |
| Nymgaard, K | 1 |
| Vaag, UH | 1 |
| Yamazumi, S | 1 |
| Yui, K | 1 |
| Endo, S | 1 |
| Yamamoto, S | 1 |
| Holden, JM | 1 |
| Kerry, RJ | 1 |
| Orme, JE | 1 |
| Jaffe, K | 1 |
| Zisook, S | 1 |
| Gelenberg, AJ | 2 |
| Cooper, DS | 1 |
| Doller, JC | 1 |
| Maloof, F | 1 |
| Hekimian, LJ | 1 |
| Friedhoff, AJ | 1 |
| Deever, E | 1 |
| Smith, RC | 1 |
| Mahapatra, RK | 1 |
| Paul, SK | 1 |
| Mahapatra, D | 1 |
| Winter, S | 1 |
1 review available for amoxapine and Depression
| Article | Year |
|---|---|
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Human | 1984 |
13 trials available for amoxapine and Depression
| Article | Year |
|---|---|
Speed of onset of action of the newer antidepressants.
Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depression; Depressive Di | 1984 |
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Human | 1984 |
Amoxapine and amitriptyline. I. Relative speed of antidepressant action.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenz | 1984 |
Amoxapine and amitriptyline. II. Specificity of cognitive effects during brief treatment of depression.
Topics: Amitriptyline; Amoxapine; Attention; Clinical Trials as Topic; Cognition; Depression; Dibenzoxazepin | 1984 |
A comparative study of amoxapine and amitriptyline for depressive illness.
Topics: Adult; Aged; Amitriptyline; Amoxapine; Clinical Trials as Topic; Depression; Dibenzoxazepines; Doubl | 1980 |
Amoxapine in the treatment of depression. A clinical evaluation in ambulant patients.
Topics: Adult; Amoxapine; Clinical Trials as Topic; Depression; Dibenzoxazepines; Drug Evaluation; Female; H | 1982 |
The efficacy of antidepressants in post-stroke depression.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Cerebrov | 1997 |
Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression.
Topics: Adult; Amoxapine; Blood Platelets; Depression; Female; Humans; Imipramine; Kinetics; Male; Middle Ag | 1979 |
Comparison of efficacy of amoxapine and imipramine in a multi-clinic double-blind study using the WHO schedule for a standard assessment of patients with depressive disorders.
Topics: Amoxapine; Clinical Trials as Topic; Depression; Dibenzoxazepines; Double-Blind Method; Drug Evaluat | 1979 |
Amoxapine versus amitriptyline in endogenous depression. A double-blind study.
Topics: Adult; Aged; Amitriptyline; Amoxapine; Bipolar Disorder; Blood Pressure; Body Weight; Clinical Trial | 1979 |
Amoxapine in depressive illness.
Topics: Amoxapine; Depression; Dibenzoxazepines; Double-Blind Method; Female; Humans; Imipramine; Male; Midd | 1979 |
A comparison of the onset of action and therapeutic efficacy of amoxapine and amitriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Amoxapine; Bipolar Disorder; Depression; Dibenzoxazepines; D | 1978 |
Amoxapine, imipramine and placebo in depressive illness.
Topics: Adult; Amoxapine; Clinical Trials as Topic; Depression; Dibenzoxazepines; Female; Humans; Imipramine | 1975 |
20 other studies available for amoxapine and Depression
| Article | Year |
|---|---|
Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants.
Topics: Amoxapine; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Duloxetine | 2011 |
[Case of prolonged recovery from serotonin syndrome caused by paroxetine].
Topics: Amoxapine; Cytochrome P-450 CYP2D6; Depression; Diagnosis, Differential; Drug Interactions; Humans; | 2003 |
Three new antidepressants amoxapine, maprotiline, and trazodone.
Topics: Amoxapine; Antidepressive Agents; Depression; Humans; Maprotiline; Trazodone | 1983 |
Hyponatremia due to antidepressant medications.
Topics: Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Depression; Doxepin; Emergencies; Female | 1983 |
Amoxapine-associated acute renal failure.
Topics: Acute Kidney Injury; Adult; Amoxapine; Depression; Dibenzoxazepines; Humans; Hypotension; Kidney Tub | 1983 |
Analysis of amoxapine and its metabolites in human plasma by high pressure liquid chromatography.
Topics: Adult; Aged; Amoxapine; Chromatography, High Pressure Liquid; Depression; Dibenzoxazepines; Female; | 1982 |
Amoxapine, an observation, and a perspective on MAOIs and their safety.
Topics: Adult; Amoxapine; Depression; Dibenzoxazepines; Female; Humans; Monoamine Oxidase Inhibitors | 1981 |
A double-blind comparison between amoxapine and amitriptyline in depressed in-patients.
Topics: Amitriptyline; Amoxapine; Depression; Dibenzoxazepines; Double-Blind Method; Drug Evaluation; Female | 1980 |
Clinical response and blood levels in the treatment of depression with a new antidepressant drug, amoxapine.
Topics: Adult; Amoxapine; Depression; Dibenzoxazepines; Double-Blind Method; Drug Evaluation; Female; Humans | 1980 |
Acute generalized exanthematous pustulosis induced by amoxapine.
Topics: Acute Disease; Amoxapine; Antidepressive Agents, Tricyclic; Depression; Drug Eruptions; Exanthema; F | 1998 |
[A case of allergic cross reaction between tricyclic antidepressants and maprotiline].
Topics: Aged; Amoxapine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cross R | 1998 |
Repeated propofol anesthesia for a patient with a history of neuroleptic malignant syndrome.
Topics: Amoxapine; Anesthesia, Intravenous; Anesthetics, Intravenous; Antidepressive Agents, Second-Generati | 1999 |
[Successful treatment using high-dose amoxapine for a depressive patient].
Topics: Amoxapine; Antidepressive Agents, Second-Generation; Depression; Follow-Up Studies; Humans; Male; Mi | 1999 |
Abnormal monoamine metabolism in cerebrospinal fluid in a case of serotonin syndrome.
Topics: Adult; Amoxapine; Biogenic Monoamines; Clomipramine; Depression; Humans; Male; Selective Serotonin R | 2000 |
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Model | 2001 |
[Effects of antidepressants (amoxapine and imipramine) on serum anterior pituitary hormone levels in patients with depressive states (author's transl)].
Topics: Adolescent; Adult; Amoxapine; Child; Depression; Dibenzoxazepines; Female; Humans; Imipramine; Male; | 1979 |
Galactorrhea in a patient treated with amoxapine.
Topics: Adult; Amoxapine; Depression; Dibenzoxazepines; Female; Galactorrhea; Humans; Lactation Disorders; P | 1978 |
Galactorrhea and hyperprolactinemia associated with amoxapine therapy. Report of a case.
Topics: Adult; Amoxapine; Depression; Dibenzoxazepines; Female; Galactorrhea; Humans; Lactation Disorders; M | 1979 |
Single case study. Amoxapine, a new antidepressant, appears in human milk.
Topics: Adult; Amoxapine; Biotransformation; Depression; Dibenzoxazepines; Female; Galactorrhea; Humans; Mil | 1979 |
Cardiovascular effects of polycyclic antidepressants.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depression; | 1986 |