| Assay ID | Title | Year | Journal | Article |
|---|
| AID1419260 | Antiproliferative activity against human M14 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1333919 | Chemical stability of the compound in pH 1 HCl buffer at 10'-4 M incubated for 75 mins by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID718488 | Upregulation of Cyclin B gene expression in human HT-29 cells at 125 to 500 uM after 24 hrs by Western blotting | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1333918 | Chemical stability of the compound in pH 7.4 phosphate buffered saline at 10'-4 M incubated for overnight by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1269940 | Cytotoxicity against human Raji cells expressing EBV-EA assessed as inhibition of TPA-induced EBV-EA activation after 48 hrs by trypan blue staining based immunofluorescence method relative to TPA | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1419289 | Cell cycle arrest in human PC3 cells assessed as accumulation at G2/M phase at 10 uM after 72 hrs by RNase/propidium iodide staining-based flow cytometric analysis (Rvb = 20 +/- 3%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419263 | Antiproliferative activity against human HCT15 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419292 | Cell cycle arrest in human PC3 cells assessed as accumulation at G2/M phase at 70 uM after 72 hrs by RNase/propidium iodide staining-based flow cytometric analysis (Rvb = 20 +/- 3%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419259 | Antiproliferative activity against human SNB19 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1569228 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as increase in trabecular thickness in femur bone at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| AID718487 | Upregulation of p21 gene expression in human HT-29 cells at > 250 uM after 24 hrs by Western blotting | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1416553 | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | | | |
| AID1333885 | Chemical stability of the compound in pH 6.7 potassium phosphate buffer at 10'-4 M incubated for overnight by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1419251 | Induction of apoptosis in human PC3 cells assessed as late apoptotic cells at 50 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 8%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718496 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of alpha-tocopherol | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1569211 | Inhibition of RANKL-induced osteoclastogenesis in C57BL/6 mouse bone marrow macrophages assessed as reduction in NFATc1 expression at 10 uM measured over 5 days by Western blot analysis | | | |
| AID718491 | Cytotoxicity against human HT-29 cells assessed as dead cells at GI70 concentration after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1333889 | Inhibition of P-gp in drug resistant human H460 cells assessed as reduction in cell viability measured after 48 hrs by sulforhodamine B assay | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID718477 | Cell cycle arrest in human HCT116 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of L-ascorbic acid | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID597177 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum Dd2 by FACS-based assay | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. |
| AID1569212 | Effect on NFkappaB expression in M-CSF induced C57BL/6 mouse bone marrow macrophages at 10 uM measured over 5 days by Western blot analysis | | | |
| AID718482 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated increase in p21 at 250 to 500 uM after 24 hrs by Western blotting in presence of N-acetyl-L-cysteine | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID718480 | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1269946 | Antioxidant activity assessed as DPPH radical scavenging activity incubated for 20 mins by spectrophotometry analysis | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1269965 | Antifungal activity against Aspergillus oryzae MTCC 262 assessed as growth inhibition after 5 to 7 days by broth dilution method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID718495 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of L-ascorbic acid | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID300497 | Cytotoxicity against human A549 cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1333891 | Inhibition of P-gp in doxorubicin resistant human K562 cells assessed as reduction in cell viability measured after 48 hrs by Presto blue assay | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1419281 | Antiproliferative activity in human PC3 cells up to 50 uM measured during 120 hrs each 15 mins by RTCA DP based cellular impedance analysis | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1269966 | Antifungal activity against Aspergillus flavus MTCC 277 assessed as growth inhibition after 5 to 7 days by broth dilution method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1333890 | Antiproliferative activity against human K562 cells measured after 48 hrs by Presto blue assay | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1419304 | Induction of apoptosis in human PC3 cells assessed as early apoptotic cells at 50 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 2%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718493 | Cytotoxicity against human HT-29 cells assessed as dead cells at 500 uM after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1569185 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage assessed as reduction in multinucleated TRAP+ cells incubated for 6 days with fresh media replacement on day 3 and measured on day 6 by TRAP staining-base | | | |
| AID379150 | Cytotoxicity against human KB cells after 2 days by sulforhodamine B assay | 2006 | Journal of natural products, Oct, Volume: 69, Issue:10
| Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents. |
| AID718483 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase at 62.5 to 250 uM after 72 hrs by propidium iodide based FACS flow cytometry | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1419254 | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718472 | Cell cycle arrest in human WI38 cells assessed as ROS-stimulated accumulation at G2/M phase at 250 uM after 24 hrs by propidium iodide based FACS flow cytometry in presence of N-acetyl-L-cysteine | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID597186 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 infected in erythrocytes assessed as inhibition of sorbitol-induced hemolysis after 15 mins | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. |
| AID1419294 | Antioxidant activity assessed as ferric ion reducing activity at 20 to 320 umol after 20 mins by FRAP assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID300494 | Cytotoxicity against human KB-VIN cells by sulforhodamine B assay | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1419303 | Induction of apoptosis in human PC3 cells assessed as necrotic cells at 50 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 14%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1416564 | Inhibition of AKT phosphorylation in human PC3 cells at 2.5 to 3.5 uM after 24 hrs by Western blot method | | | |
| AID1416551 | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay | | | |
| AID1419317 | Induction of apoptosis in human PC3 cells assessed as intracellular ROS levels by measuring fluoresence intensity at 50 uM after 24 hrs by DCFH-DA staining-based flow cytometric analysis (Rvb = 3176 +/- 398 No_unit) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1333917 | Chemical stability of the compound in pH 5 sodium acetate buffer at 10'-4 M incubated for overnight by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1569229 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as reduction in trabecular separation in femur bone at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| AID1569236 | Cytotoxicity against mouse RAW264.7 cells after 24 hrs by MTT assay | | | |
| AID249543 | Inhibitory concentration against peroxidation of rabbits red blood cell (RBC) membrane ghost induced by gamma-ray irradiation | 2005 | Bioorganic & medicinal chemistry letters, Jun-02, Volume: 15, Issue:11
| Quantitative structure-activity relationship studies for antioxidant hydroxybenzalacetones by quantum chemical- and 3-D-QSAR(CoMFA) analyses. |
| AID1419305 | Induction of apoptosis in human PC3 cells assessed as viable cells at 50 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 70%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419258 | Antiproliferative activity against human A498 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1269941 | Antifungal activity against Rhizoctonia solani Kuhn assessed as growth inhibition after 2 to 3 days by poisoned food method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1419264 | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1269959 | Fungicidal activity against Aspergillus oryzae MTCC 262 after 5 to 7 days by agar well diffusion method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1269964 | Fungicidal activity against Penicillium chrysogenum MTCC 616 after 5 to 7 days by agar well diffusion method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1269962 | Fungicidal activity against Aspergillus ochraceus MTCC 4643 after 5 to 7 days by agar well diffusion method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1419312 | Induction of mitochondrial membrane potential loss in human PC3 cells assessed as fluorescence intensity at 50 uM after 24 hrs by TMRE dye-based flow cytometric analysis (Rvb = 10101 +/- 853 No_unit) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419287 | Cell cycle arrest in human PC3 cells assessed as accumulation at G0/G1 phase at 10 uM after 72 hrs by RNase/propidium iodide staining-based flow cytometric analysis (Rvb = 61 +/- 3%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718479 | Cytotoxicity against human HCT15 cells assessed as growth inhibition after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1419282 | Antimigratory activity in human PC3 cells up to 50 uM measured during 120 hrs each 15 mins by RTCA DP based cellular impedance analysis | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1169237 | Neuroprotective activity against glutamate-induced neuronal cell death in mouse HT22 cells assessed as increase in cell viability at 1 to 25 uM after 24 hrs by MTT assay relative to control | 2014 | Journal of natural products, Oct-24, Volume: 77, Issue:10
| Synthesis of natural and non-natural curcuminoids and their neuroprotective activity against glutamate-induced oxidative stress in HT-22 cells. |
| AID1269960 | Fungicidal activity against Aspergillus flavus MTCC 277 after 5 to 7 days by agar well diffusion method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID379151 | Cytotoxicity against multidrug-resistant human KB-VCR cells after 2 days by sulforhodamine B assay | 2006 | Journal of natural products, Oct, Volume: 69, Issue:10
| Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents. |
| AID1348958 | Effect on firefly luciferase activity expressed in human HepG2 cells at low concentration after 5 hrs by luminescence assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Activation of anti-oxidant Nrf2 signaling by enone analogues of curcumin. |
| AID379152 | Cytotoxicity against human A549 cells after 2 days by sulforhodamine B assay | 2006 | Journal of natural products, Oct, Volume: 69, Issue:10
| Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents. |
| AID718475 | Cell cycle arrest in human HCT15 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of N-acetyl-L-cysteine | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID300498 | Cytotoxicity against human 1A9 cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1569250 | Toxicity in ddY mouse model of OVX-induced osteoporosis assessed as increase in body weight at 10 mg/kg, po administered once daily via gavage for 4 weeks measured 5 weeks post OVX-challenge | | | |
| AID272869 | Displacement of [125I]IMSB from beta amyloid protein 40 | 2006 | Journal of medicinal chemistry, Oct-05, Volume: 49, Issue:20
| Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging. |
| AID1419257 | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718497 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of MnTBAP | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID718490 | Cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at > 250 uM after 24 hrs by propidium iodide based FACS flow cytometry relative to control | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID597176 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 by FACS-based assay | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. |
| AID249545 | Inhibitory concentration against peroxidation of rabbits red blood cell (RBC) membrane ghost induced by BuOOH (tert-butyl hydroperoxide) | 2005 | Bioorganic & medicinal chemistry letters, Jun-02, Volume: 15, Issue:11
| Quantitative structure-activity relationship studies for antioxidant hydroxybenzalacetones by quantum chemical- and 3-D-QSAR(CoMFA) analyses. |
| AID1569195 | Osteo-blastogenic activity in mouse MC3T3-E1 cells assessed as stimulation of ALP activity at 50 uM supplemented with fresh medium every 3 to 4 days and measured after 14 days relative to control | | | |
| AID718470 | Induction of ROS generation in human HT-29 cells at 250 uM after 24 hrs by FACS flow cytometry | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1269970 | Antifungal activity against Penicillium chrysogenum MTCC 616 assessed as growth inhibition after 5 to 7 days by broth dilution method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1569220 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as increase in femur bone mineral density at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| AID1419308 | Induction of apoptosis in human PC3 cells assessed as viable cells at 150 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 70%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1569194 | Osteo-blastogenic activity in mouse MC3T3-E1 cells assessed as stimulation of ALP activity at 10 uM supplemented with fresh medium every 3 to 4 days and measured after 14 days relative to control | | | |
| AID718485 | Cell cycle arrest in human HT-29 cells transfected with p21 siRNA assessed as accumulation at G2/M phase at 500 uM after 24 hrs by propidium iodide based FACS flow cytometry | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1419293 | Induction of apoptosis in human PC3 cells assessed as late apoptotic cells at 150 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 8%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718474 | Cell cycle arrest in human HCT15 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of L-ascorbic acid | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID597185 | Inhibition of Plasmodium falciparum falcipain 2 assessed as benzyloxycarbonyl-Phe-Leu-7-amino-4-methylcoumarin substrate hydrolysis after 30 mins by spectrofluorometry analysis | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. |
| AID718484 | Induction of ROS generation in human HT-29 cells at > 250 uM after 24 hrs by FACS flow cytometry | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1333921 | Stability of the compound at -20 degreeC at 10'-4 M incubated for 6 to 12 days under dark condition by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID300503 | Cytotoxicity against human LN-Cap cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1419256 | Antiproliferative activity against HSF cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718498 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of PEG-penetreated catalase | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1419313 | Induction of mitochondrial membrane potential loss in human PC3 cells assessed as fluorescence intensity at 150 uM after 24 hrs by TMRE dye-based flow cytometric analysis (Rvb = 10101 +/- 853 No_unit) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419255 | Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID300500 | Cytotoxicity against human ZR751 cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1333922 | Stability of the compound at 4 degreeC at 10'-4 M incubated for 6 to 12 days under dark condition by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1419306 | Induction of apoptosis in human PC3 cells assessed as necrotic cells at 150 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 14%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419307 | Induction of apoptosis in human PC3 cells assessed as early apoptotic cells at 150 uM after 24 hrs by Annexin V-PE/7-AAD staining-based flow cytometric analysis (Rvb = 2%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419265 | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419288 | Cell cycle arrest in human PC3 cells assessed as accumulation at S phase at 10 uM after 72 hrs by RNase/propidium iodide staining-based flow cytometric analysis (Rvb = 17 +/- 1%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718478 | Cell cycle arrest in human HCT116 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of N-acetyl-L-cysteine | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID718476 | Cell cycle arrest in human HCT116 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of alpha-tocopherol | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1333925 | Stability of the compound in HEPES medium at 1.5 10'-3 M incubated for 5 to 30 mins under dark condition by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1569208 | Inhibition of RANKL-induced osteoclastogenesis in C57BL/6 mouse bone marrow macrophages assessed as increase in NFkappaB expression at 10 uM measured over 5 days by Western blot analysis | | | |
| AID1269967 | Antifungal activity against Aspergillus niger MTCC 218 assessed as growth inhibition after 5 to 7 days by broth dilution method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1269963 | Fungicidal activity against Fusarium oxysporum MTCC 1755 after 5 to 7 days by agar well diffusion method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID300493 | Cytotoxicity against human KB cells by sulforhodamine B assay | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID272868 | Displacement of [125I]IMPY from beta amyloid protein 40 | 2006 | Journal of medicinal chemistry, Oct-05, Volume: 49, Issue:20
| Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging. |
| AID718469 | Cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at 250 uM after 24 hrs by propidium iodide based FACS flow cytometry | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1569214 | Suppression of NFATc1 expression in M-CSF induced C57BL/6 mouse bone marrow macrophages at 10 uM measured over 5 days by Western blot analysis | | | |
| AID1269969 | Antifungal activity against Fusarium oxysporum MTCC 1755 assessed as growth inhibition after 5 to 7 days by broth dilution method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID1333923 | Stability of the compound at room temperature at 10'-4 M incubated for 6 to 12 days under dark condition by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID597184 | Ratio of compound IC50 to hematin IC50 for inhibition of beta-hematin formation | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. |
| AID1416552 | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay | | | |
| AID300496 | Cytotoxicity against human KB-VIN cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1333916 | Chemical stability of the compound in pH 9.1 sodium boric acid buffer at 10'-4 M incubated for overnight by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1269971 | Antioxidant activity assessed as ABTS free radical scavenging activity | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID300499 | Cytotoxicity against human HCT8 cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1269961 | Fungicidal activity against Aspergillus niger MTCC 218 after 5 to 7 days by agar well diffusion method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID718489 | Upregulation of CDK1 gene expression in human HT-29 cells at 125 to 500 uM after 24 hrs by Western blotting | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1169233 | Cytotoxicity against mouse HT22 cells assessed as cell viability at 1 to 25 uM after 24 hrs by MTT assay relative to control | 2014 | Journal of natural products, Oct-24, Volume: 77, Issue:10
| Synthesis of natural and non-natural curcuminoids and their neuroprotective activity against glutamate-induced oxidative stress in HT-22 cells. |
| AID1269968 | Antifungal activity against Aspergillus ochraceus MTCC 4643 assessed as growth inhibition after 5 to 7 days by broth dilution method | 2016 | Bioorganic & medicinal chemistry, Feb-15, Volume: 24, Issue:4
| An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG). |
| AID718473 | Cell cycle arrest in human HCT15 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of alpha-tocopherol | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID718471 | Cytotoxicity against human WI38 cells assessed as growth inhibition after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID597178 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 by FACS-based assay | 2011 | Journal of medicinal chemistry, May-26, Volume: 54, Issue:10
| Enone- and chalcone-chloroquinoline hybrid analogues: in silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies. |
| AID718481 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase at 125 to 500 uM after 24 hrs by propidium iodide based FACS flow cytometry in presence of N-acetyl-L-cysteine | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1569241 | Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay | | | |
| AID718467 | Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID718486 | Upregulation of p21 gene expression in human HT-29 cells assessed as decrease in phosphorylated CDK1 at Thr161 at 500 uM after 24 hrs by Western blotting | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID300502 | Cytotoxicity against human DU145 cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID300495 | Cytotoxicity against human KB cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1419318 | Induction of apoptosis in human PC3 cells assessed as intracellular ROS levels by measuring fluoresence intensity at 150 uM after 24 hrs by DCFH-DA staining-based flow cytometric analysis (Rvb = 3176 +/- 398 No_unit) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419283 | Antiproliferative activity in human PC3 cells at 2 to 10 uM measured during 120 hrs each 15 mins by RTCA DP based cellular impedance analysis | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID718468 | Upregulation of p21 gene expression in human HT-29 cells at 250 uM after 24 hrs by Western blotting | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID718499 | Cell cycle arrest in human HT-29 cells assessed as ROS-stimulated accumulation at G2/M phase after 24 hrs by propidium iodide based FACS flow cytometry in presence of SOD | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1569227 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as increase in trabecular number in femur bone at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| AID1419261 | Antiproliferative activity against human OVCAR4 cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419290 | Cell cycle arrest in human PC3 cells assessed as accumulation at G0/G1 phase at 70 uM after 72 hrs by RNase/propidium iodide staining-based flow cytometric analysis (Rvb = 61 +/- 3%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1419262 | Antiproliferative activity against human NCI-H322M cells after 72 hrs by MTT assay | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID300501 | Cytotoxicity against human PC3 cells | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18
| Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents. |
| AID1333888 | Antiproliferative activity against human NCI-H460 cells measured after 48 hrs by sulforhodamine B assay | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID718492 | Cytotoxicity against human HT-29 cells assessed as dead cells at 1000 uM after 72 hrs by WST-8 assay | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12
| Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells. |
| AID1569224 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as increase in cross-sectional thickness in femur bone at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| AID1419291 | Cell cycle arrest in human PC3 cells assessed as accumulation at S phase at 70 uM after 72 hrs by RNase/propidium iodide staining-based flow cytometric analysis (Rvb = 17 +/- 1%) | 2018 | Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
| Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane. |
| AID1569232 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as increase in new bone volume in femur bone at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| AID1333920 | Stability of the compound in RPMI medium at 1.5 10'-3 M incubated for 5 to 30 mins under dark condition by HPLC method | 2017 | Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
| A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells. |
| AID1569222 | Antiosteoporotic activity in ddY mouse model of OVX-induced osteoporosis assessed as increase in ratio of bone volume/trabecular volume in femur bone at 10 mg/kg, po administered once daily via gavage for 4 weeks by microcomputed tomographic analysis | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |