Page last updated: 2024-10-16

betaine and Depression

betaine has been researched along with Depression in 7 studies

glycine betaine : The amino acid betaine derived from glycine.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations."7.85Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017)
"Betaine is a natural product with an anti-inflammatory and antioxidant activities."7.11Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior. ( Meng, LQ; Peng, XD; Quan, HF; Shi, H; Wang, XL; Yan, L; Yang, HF; Zhang, M, 2022)
"21]) were associated with higher odds of antepartum depression and 4 metabolites (betaine [OR = =0."3.96Metabolomic markers of antepartum depression and suicidal ideation. ( Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA, 2020)
"This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations."3.85Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017)
"Ketamine is emerging as a new hope against depression, but ketamine-associated psychotomimetic effects limit its clinical use."3.83Betaine enhances antidepressant-like, but blocks psychotomimetic effects of ketamine in mice. ( Chan, MH; Chen, HH; Chen, YC; Lee, MY; Lin, JC, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Haramipour, P1
Asghari, A1
Hassanpour, S1
Jahandideh, A1
Zhang, M1
Wang, XL1
Shi, H1
Meng, LQ1
Quan, HF1
Yan, L1
Yang, HF1
Peng, XD1
Mitro, SD1
Larrabure-Torrealva, GT1
Sanchez, SE1
Molsberry, SA1
Williams, MA1
Clish, C1
Gelaye, B1
van Lee, L1
Quah, PL1
Saw, SM1
Yap, FKP1
Godfrey, KM1
Chong, YS1
Meaney, MJ1
Chen, H1
Chong, MF1
Perrin, G1
Berdot, S1
Thomas, F1
Pannier, B1
Danchin, N1
Durieux, P1
Sabatier, B1
Lin, JC1
Lee, MY1
Chan, MH1
Chen, YC1
Chen, HH1
Setoyama, D1
Kato, TA1
Hashimoto, R1
Kunugi, H1
Hattori, K1
Hayakawa, K1
Sato-Kasai, M1
Shimokawa, N1
Kaneko, S1
Yoshida, S1
Goto, YI1
Yasuda, Y1
Yamamori, H1
Ohgidani, M1
Sagata, N1
Miura, D1
Kang, D1
Kanba, S1

Trials

1 trial available for betaine and Depression

ArticleYear
Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Animals; Anti-Inflammatory Agents; Betaine; Cyclooxygenase 2; Cytokines; Depression; Inflammasomes;

2022

Other Studies

6 other studies available for betaine and Depression

ArticleYear
Anti-depressant Effect of Betaine Mediates via Nitrergic and Serotoninergic Systems in Ovariectomized Mice.
    Archives of Razi Institute, 2021, Volume: 76, Issue:5

    Topics: Animals; Antidepressive Agents; Betaine; Depression; Female; Mice; NG-Nitroarginine Methyl Ester; Ni

2021
Metabolomic markers of antepartum depression and suicidal ideation.
    Journal of affective disorders, 2020, 02-01, Volume: 262

    Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Dep

2020
Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort.
    Depression and anxiety, 2017, Volume: 34, Issue:10

    Topics: Adult; Anxiety; Betaine; Choline; Cohort Studies; Depression; Female; Humans; Personal Satisfaction;

2017
Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study.
    BMJ open, 2018, 07-30, Volume: 8, Issue:7

    Topics: Acetaminophen; Adult; Antipyretics; Aspirin; Betaine; Body Mass Index; Cross-Sectional Studies; Depr

2018
Betaine enhances antidepressant-like, but blocks psychotomimetic effects of ketamine in mice.
    Psychopharmacology, 2016, Volume: 233, Issue:17

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Betaine; Depression; Excitatory Amino Acid Antagon

2016
Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: 3-Hydroxybutyric Acid; Betaine; Biomarkers; Chromatography, Liquid; Citric Acid; Creatinine; Depress

2016