Assay ID | Title | Year | Journal | Article |
AID672470 | Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric analysis | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15
| Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B. |
AID780312 | Displacement of [3H]5-HT from human recombinant 5HT1E receptor stably expressed in HEK cells | 2013 | Bioorganic & medicinal chemistry, Nov-15, Volume: 21, Issue:22
| In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. |
AID338916 | Antimalarial activity against Plasmodium falciparum D6 | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4
| New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. |
AID336710 | Cytotoxicity against mouse L1210 cells | 1994 | Journal of natural products, Jul, Volume: 57, Issue:7
| Two new tryptophan-derived alkaloids from the Okinawan marine sponge Aplysina sp. |
AID780310 | Displacement of [3H]LSD from human recombinant 5HT2B receptor stably expressed in HEK cells | 2013 | Bioorganic & medicinal chemistry, Nov-15, Volume: 21, Issue:22
| In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. |
AID672472 | Selectivity ratio of IC50 for human recombinant MAO-B to IC50 for human recombinant MAO-A | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15
| Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B. |
AID780311 | Displacement of [3H]ketanserin from rat 5HT2A receptor stably expressed in 3T3 cells | 2013 | Bioorganic & medicinal chemistry, Nov-15, Volume: 21, Issue:22
| In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. |
AID338917 | Cytotoxicity against african green monkey Vero cells at 4.76 ug/mL | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4
| New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. |
AID338926 | Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells at 30 uM by scintillation spectroscopy | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4
| New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. |
AID780309 | Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in Flp-IN HEK cells | 2013 | Bioorganic & medicinal chemistry, Nov-15, Volume: 21, Issue:22
| In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. |
AID780308 | Displacement of [3H]GR65630 from human recombinant 5HT3 receptor expressed in HEKT cells | 2013 | Bioorganic & medicinal chemistry, Nov-15, Volume: 21, Issue:22
| In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. |
AID780305 | Displacement of [3H]LSD from human recombinant 5HT6 receptor stably expressed in HEK cells | 2013 | Bioorganic & medicinal chemistry, Nov-15, Volume: 21, Issue:22
| In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. |
AID338925 | Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells at 30 uM by scintillation spectroscopy | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4
| New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. |
AID338927 | Displacement of [3H]methylspiperone form human cloned dopamine 4.2 receptor | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4
| New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. |
AID672471 | Inhibition of human recombinant MAO-B using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric analysis | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15
| Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B. |
AID336712 | Cytotoxicity against human KB cells | 1994 | Journal of natural products, Jul, Volume: 57, Issue:7
| Two new tryptophan-derived alkaloids from the Okinawan marine sponge Aplysina sp. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |