6-hydroxynorketamine has been researched along with Depression in 6 studies
*Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 5 (83.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gould, TD; Hagen, NR; Highland, JN; Konrath, KM; Moaddel, R; Morris, PJ; Powels, CF; Riggs, LM; Thomas, CJ; Wang, AQ; Zanos, P | 1 |
| Ju, L; Liu, P; Yang, J; Zhu, T | 1 |
| Chou, D | 1 |
| Aleksandrova, LR; Phillips, AG; Wang, YT | 1 |
| Brannigan, G; Bu, W; Eckenhoff, RG; Joseph, TT; Lin, W; Liu, R; Yeliseev, A; Zoubak, L | 1 |
| Chang, L; Chen, J; Fujita, Y; Hashimoto, K; Ma, M; Pu, Y; Xiong, Z; Zhang, K | 1 |
6 other study(ies) available for 6-hydroxynorketamine and Depression
| Article | Year |
|---|---|
Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (2
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Female; Ketamine; Male; Mice | 2022 |
BDNF-TrkB signaling-mediated upregulation of Narp is involved in the antidepressant-like effects of (2R,6R)-hydroxynorketamine in a chronic restraint stress mouse model.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Depression; Disease Models, Animal; Female; Ketamine; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Receptor, trkB; Up-Regulation | 2022 |
Brain-derived neurotrophic factor in the ventrolateral periaqueductal gray contributes to (2R,6R)-hydroxynorketamine-mediated actions.
Topics: Aggression; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Female; Ketamine; Male; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 2020 |
Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression.
Topics: Animals; Depression; Disease Models, Animal; Hippocampus; Immobilization; Ketamine; Long-Term Potentiation; Male; Motor Activity; Open Field Test; Rats, Inbred WKY; Spatial Memory; Stress, Psychological; Swimming; Synaptic Transmission | 2020 |
Ketamine Metabolite (2
Topics: Antidepressive Agents; Depression; Ketamine; Receptors, Opioid, kappa | 2021 |
Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model.
Topics: Animals; Antidepressive Agents; Biomarkers; Bone Density; Depression; Depressive Disorder; Disease Models, Animal; Inflammation; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Osteopontin; Osteoprotegerin; RANK Ligand; Stress, Psychological | 2019 |