Page last updated: 2024-09-03

pramipexole and Depression

pramipexole has been researched along with Depression in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (32.43)29.6817
2010's16 (43.24)24.3611
2020's9 (24.32)2.80

Authors

AuthorsStudies
Dong, AQ; Li, D; Liu, CF; Mao, CJ; Ren, C; Wang, CT; Wang, F; Wei, SZ; Yao, XY; Zhang, JB; Zhang, YT1
Attenburrow, MJ; Au-Yeung, SK; Bogacz, R; Browning, M; Chan, F; Cipriani, A; Cleare, A; Cowen, P; Edwards, C; Evans, J; Geddes, J; Griffiths, J; Harmer, CJ; Harrison, PJ; Kessler, D; Lewis, G; Rendell, J; Roberts, S; Shanyinde, M; Simon, J; Singh, I; Watson, S; Yu, LM1
Chen, J; Liu, W; Liu, Z; Ning, H; Ren, J; Shen, L; Tian, Z; Wang, H; Wang, Z; Yang, N; Yuan, C; Zhao, Y; Zheng, H; Zhou, G; Zhou, H1
Asp, M; Björkstrand, J; Deierborg, T; Eklund, M; Jensen, J; Lindahl, J; Lindqvist, D; Månsson, K; Ståhl, D; Svensson, M; Tjernberg, J; Tornberg, Å; van Westen, D; Ventorp, F1
Abi-Dargham, A; Ang, YS; Iosifescu, DV; McGrath, PJ; Pizzagalli, DA; Reinen, JM; Schneier, FR; Slifstein, M; Whitton, AE1
Escalona, R; Fawcett, J; Rush, AJ1
Abbasi, MH; Esmaeili, S; Habibi, SA; Shahidi, GA1
Jiang, DQ; Jiang, LL; Li, MX; Wang, Y1
Dutra, RC; Felipetti, FA; Gonçalves, ECD; Horewicz, VV; Lieberknecht, V; Martins, DF; Rabelo, BD; Rodrigues, ALS1
Chen, T; Chen, Y; Jia, Y; Li, G; Wang, B; Wang, J; Zhou, T; Zhu, L1
Batista, LM; Havnaer, A; Kalinaga, B1
Dong, J; Liu, J; Su, Y; Sun, S; Wang, L; Yan, P1
Asanuma, M; Kitamura, Y; Kuwatsuka, K; Miyazaki, I; Onoue, Y; Sendo, T1
Berghauzen-Maciejewska, K; Dziubina, A; Głowacka, U; Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J1
Chiu, WH; Depboylu, C; Hermanns, G; Höglinger, GU; Maurer, L; Oertel, WH; Ries, V; Windolph, A1
Cho, YW; Choi, JW; Jung, KY; Kim, KH; Kim, SM; Koo, YS; Lee, BU; Lee, C; Lee, SK; Song, JY1
Boulet, S; Carcenac, C; Carnicella, S; David, O; Krack, P; Magnard, R; Savasta, M; Vachez, Y1
Coelho, ID; Cunha, MP; Dafre, AL; de Souza, LF; Dos Santos, AR; Dutra, RC; Junqueira, SC; Lieberknecht, V; Rodrigues, AL1
Henry, C; Masson, M1
Iakhno, NN; Nodel', MR1
Antonini, A1
Asanuma, M; Gomita, Y; Kawasaki, H; Kitagawa, K; Kitamura, Y; Miyaoka, J; Miyazaki, T; Sendo, T1
Breuer, ME; Buerger, E; Ferger, B; Groenink, L; Korte, M; Olivier, B; Oosting, RS1
Barone, P1
Allen, RP; Earley, CJ; Edwards, RR; Greenbaum, S; Quartana, PJ; Smith, MT1
Hamaguchi, H; Kanda, F; Sekiguchi, K; Yasui, N1
Gass, P; Hellweg, R; Hörtnagl, H; Schulte-Herbrüggen, O; Vogt, MA1
Harada, T; Horie, N; Ishizaki, F; Katsuoka, H; Nagakane, T; Nitta, K; Nitta, Y; Sasaki, T; Yamada, T; Yasumatsu, Y1
Hori, H; Kunugi, H1
Bares, M; Dostál, V; Ehler, E; Fanfrdlová, Z; Fiedler, J; Klajblová, H; Kulist'ák, P; Rektor, I; Rektorová, I; Ressner, P; Svátová, J; Urbánek, K; Velísková, J1
Köster, J; Möller, JC; Oertel, WH; Pezzoli, G; Provinciali, L1
Brecht, HM; Koester, J; Kraus, PH; Lemke, MR; Reichmann, H1
Möller, JC; Oertel, WH1
Brecht, HM; Koester, J; Lemke, MR; Reichmann, H1
Chigir', IP; Fedorova, NV2
Ball, J1

Reviews

5 review(s) available for pramipexole and Depression

ArticleYear
The role of pramipexole in the treatment of patients with depression and Parkinson's disease: A meta-analysis of randomized controlled trials.
    Asian journal of psychiatry, 2021, Volume: 61

    Topics: Depression; Humans; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Treatment Outcome

2021
Comparative efficacy and acceptability of antidepressants in Parkinson's disease: a network meta-analysis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Antidepressive Agents, Tricyclic; Benzothiazoles; Depression; Humans; Odds Ratio; Parkinson Disease; Pergolide; Pramipexole; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2013
What can rodent models tell us about apathy and associated neuropsychiatric symptoms in Parkinson's disease?
    Translational psychiatry, 2016, Mar-08, Volume: 6

    Topics: Anhedonia; Animals; Anxiety; Apathy; Behavior, Animal; Benzothiazoles; Depression; Disease Models, Animal; Dopamine Agonists; Mice; Neostriatum; Parkinson Disease; Pramipexole; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Substantia Nigra

2016
Treatment of depressive symptoms in Parkinson's disease.
    European journal of neurology, 2011, Volume: 18 Suppl 1

    Topics: Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Depression; Desipramine; Dopamine Agonists; Humans; Levodopa; Nortriptyline; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline

2011
Pramipexole in the treatment of Parkinson's disease: new developments.
    Expert review of neurotherapeutics, 2005, Volume: 5, Issue:5

    Topics: Antiparkinson Agents; Benzothiazoles; Depression; Expert Testimony; Humans; Parkinson Disease; Pramipexole; Product Surveillance, Postmarketing; Thiazoles; Tremor

2005

Trials

9 trial(s) available for pramipexole and Depression

ArticleYear
PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression.
    Evidence-based mental health, 2022, Volume: 25, Issue:2

    Topics: Antidepressive Agents; Depression; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Humans; Pramipexole; Quality of Life; Randomized Controlled Trials as Topic

2022
Zishen pingchan granules combined with pramipexole in the improvement of depressive symptoms in Parkinson's disease: a prospective, multicenter, randomized, double-blind, controlled clinical study.
    Journal of translational medicine, 2022, 08-12, Volume: 20, Issue:1

    Topics: Aged; Benzothiazoles; Depression; Double-Blind Method; Humans; Parkinson Disease; Pramipexole; Prospective Studies; Quality of Life; Severity of Illness Index; Treatment Outcome

2022
Add-on pramipexole for anhedonic depression: study protocol for a randomised controlled trial and open-label follow-up in Lund, Sweden.
    BMJ open, 2023, Nov-30, Volume: 13, Issue:11

    Topics: Anhedonia; Depression; Follow-Up Studies; Humans; Pramipexole; Randomized Controlled Trials as Topic; Sweden

2023
The efficacy of pramipexole, a dopamine receptor agonist, as an adjunctive treatment in treatment-resistant depression: an open-label trial.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Adult; Benzothiazoles; Depression; Dopamine Agonists; Female; Humans; Male; Middle Aged; Pramipexole

2012
Pramipexole and pergolide in the treatment of depression in Parkinson's disease: a national multicentre prospective randomized study.
    European journal of neurology, 2003, Volume: 10, Issue:4

    Topics: Activities of Daily Living; Aged; Analysis of Variance; Antiparkinson Agents; Benzothiazoles; Cross-Over Studies; Depression; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Motor Activity; Parkinson Disease; Pergolide; Placebos; Pramipexole; Prospective Studies; Psychiatric Status Rating Scales; Severity of Illness Index; Single-Blind Method; Thiazoles; Treatment Outcome

2003
Long-term efficacy and safety of pramipexole in advanced Parkinson's disease: results from a European multicenter trial.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Demography; Depression; Disorders of Excessive Somnolence; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Parkinson Disease; Pramipexole; Severity of Illness Index; Thiazoles; Tremor

2005
Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole.
    The Journal of neuropsychiatry and clinical neurosciences, 2005,Spring, Volume: 17, Issue:2

    Topics: Activities of Daily Living; Aged; Aging; Antiparkinson Agents; Benzothiazoles; Depression; Dose-Response Relationship, Drug; Female; Humans; Male; Parkinson Disease; Pramipexole; Prospective Studies; Psychiatric Status Rating Scales; Psychomotor Performance; Thiazoles

2005
Effects of the dopamine agonist pramipexole on depression, anhedonia and motor functioning in Parkinson's disease.
    Journal of the neurological sciences, 2006, Oct-25, Volume: 248, Issue:1-2

    Topics: Aged; Benzothiazoles; Chi-Square Distribution; Depression; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Mood Disorders; Movement Disorders; Parkinson Disease; Pramipexole; Prospective Studies; Psychiatric Status Rating Scales; Severity of Illness Index

2006
Use of the dopamine receptor agonist Mirapex in the treatment of Parkinson's disease.
    Neuroscience and behavioral physiology, 2007, Volume: 37, Issue:6

    Topics: Activities of Daily Living; Aged; Anxiety; Benzothiazoles; Depression; Dopamine Agonists; Female; Humans; Male; Middle Aged; Parkinson Disease; Pramipexole; Review Literature as Topic; Time Factors

2007

Other Studies

23 other study(ies) available for pramipexole and Depression

ArticleYear
Pramipexole regulates depression-like behavior via dopamine D3 receptor in a mouse model of Parkinson's disease.
    Brain research bulletin, 2021, Volume: 177

    Topics: Animals; Benzothiazoles; Depression; Dopamine Agonists; Humans; Mice; Mice, Knockout; Parkinson Disease; Pramipexole; Quality of Life; Receptors, Dopamine D3

2021
Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression.
    Brain : a journal of neurology, 2020, 02-01, Volume: 143, Issue:2

    Topics: Adult; Depression; Depressive Disorder, Major; Dopamine; Dopamine Agonists; Dopamine Antagonists; Female; Humans; Learning; Male; Middle Aged; Pramipexole; Reward

2020
Pramipexole Augmentation of Buprenorphine Improves Pain and Depression in Opioid Use Disorder: A Case Report.
    The primary care companion for CNS disorders, 2020, Oct-15, Volume: 22, Issue:5

    Topics: Analgesics, Opioid; Buprenorphine; Depression; Humans; Opioid-Related Disorders; Pain; Pramipexole

2020
Dilemma in Parkinson's Treatment; Levodopa Monotherapy May be the Best Choice.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 79

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Depression; Drug Combinations; Female; Hallucinations; Humans; Levodopa; Middle Aged; Movement; Parkinson Disease; Pramipexole; Psychotic Disorders; Quality of Life

2020
Dopaminergic Receptors as Neuroimmune Mediators in Experimental Autoimmune Encephalomyelitis.
    Molecular neurobiology, 2021, Volume: 58, Issue:11

    Topics: Anhedonia; Animals; Axons; Brain-Derived Neurotrophic Factor; Corpus Striatum; Depression; Disease Progression; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Female; Interleukin-1beta; Lymph Nodes; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Oxidative Stress; Peptide Fragments; Pramipexole; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Single-Blind Method; Spinal Cord

2021
The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.
    The international journal of neuropsychopharmacology, 2018, 05-01, Volume: 21, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Depression; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Fluorenes; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Piperazines; Pramipexole; Prefrontal Cortex; Receptors, Dopamine D3; Signal Transduction; Ventral Tegmental Area

2018
Pathological Gambling in a Patient on a Dopamine Agonist.
    Rhode Island medical journal (2013), 2019, 06-04, Volume: 102, Issue:5

    Topics: Depression; Dopamine Agonists; Female; Gambling; Humans; Middle Aged; Pramipexole; Restless Legs Syndrome; Suicidal Ideation

2019
Effects of bupropion and pramipexole on cell proliferation in the hippocampus of adrenocorticotropic hormone-treated rats.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzothiazoles; Bupropion; Cell Proliferation; Depression; Dopamine; Dopamine Agents; Dopamine Agonists; Hippocampus; Male; Neurogenesis; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2

2014
Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease.
    Behavioural brain research, 2014, Sep-01, Volume: 271

    Topics: Animals; Antidepressive Agents; Benzothiazoles; Depression; Disease Models, Animal; Dopamine Agonists; Fluoxetine; Imipramine; Male; Motor Activity; Oxidopamine; Parkinson Disease; Pramipexole; Rats; Rats, Wistar; Swimming; Treatment Outcome

2014
Long-term treatment with L-DOPA or pramipexole affects adult neurogenesis and corresponding non-motor behavior in a mouse model of Parkinson's disease.
    Neuropharmacology, 2015, Volume: 95

    Topics: Animals; Antiparkinson Agents; Anxiety; Benzothiazoles; Depression; Hippocampus; Levodopa; Male; Mice, Inbred C57BL; Neurogenesis; Neurons; Olfactory Bulb; Oxidopamine; Parkinsonian Disorders; Pramipexole; Random Allocation

2015
Sternberg working memory performance following treatment with pramipexole in patients with moderate-to-severe restless legs syndrome.
    Sleep medicine, 2015, Volume: 16, Issue:6

    Topics: Adult; Benzothiazoles; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Event-Related Potentials, P300; Female; Follow-Up Studies; Humans; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Pramipexole; Reaction Time; Restless Legs Syndrome

2015
Antidepressant-like effect of pramipexole in an inflammatory model of depression.
    Behavioural brain research, 2017, 03-01, Volume: 320

    Topics: Animals; Benzothiazoles; Brain; Depression; Disease Models, Animal; Dopamine Agonists; Female; Glial Fibrillary Acidic Protein; Illness Behavior; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Locomotion; Malondialdehyde; Mice; Pramipexole; Swimming; Time Factors; Tyrosine

2017
[Depression following mania: A specific entity in bipolar disorder?]
    L'Encephale, 2017, Volume: 43, Issue:1

    Topics: Benzothiazoles; Bipolar Disorder; Depression; Disease Progression; Dopaminergic Neurons; Humans; Pramipexole; Suicidal Ideation

2017
[Mirapex (pramipexole) in the treatment of non-motor disturbances in Parkinson's disease].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:5

    Topics: Antiparkinson Agents; Anxiety; Benzothiazoles; Depression; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Middle Aged; Parkinson Disease; Pramipexole; Receptors, Dopamine D1; Sleep Wake Disorders; Treatment Outcome

2008
Unraveling depression in Parkinson's disease.
    European journal of neurology, 2008, Volume: 15, Issue:9

    Topics: Antidepressive Agents; Benzothiazoles; Clinical Trials as Topic; Cohort Studies; Depression; Depressive Disorder; Dopamine; Dopamine Agonists; Drug Interactions; Humans; Multicenter Studies as Topic; Parkinson Disease; Pramipexole; Quality of Life; Serotonin; Sertraline

2008
Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 380, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzothiazoles; Depression; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Microinjections; Motor Activity; Nucleus Accumbens; Pramipexole; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Swimming

2009
Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Animals; Antidepressive Agents; Benzothiazoles; Brain; Depression; Hyperkinesis; Male; Neuronal Plasticity; Olfactory Bulb; Pramipexole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes; Time Factors

2009
Alterations in pain responses in treated and untreated patients with restless legs syndrome: associations with sleep disruption.
    Sleep medicine, 2011, Volume: 12, Issue:6

    Topics: Aged; Benzothiazoles; Cold Temperature; Cross-Sectional Studies; Depression; Dopamine Agonists; Female; Hot Temperature; Humans; Male; Middle Aged; Pain Threshold; Pramipexole; Pressure; Psychophysics; Restless Legs Syndrome; Sleep Wake Disorders; Surveys and Questionnaires

2011
The effect of pramipexole on depressive symptoms in Parkinson's disease.
    The Kobe journal of medical sciences, 2011, Feb-02, Volume: 56, Issue:5

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Depression; Female; Humans; Male; Middle Aged; Parkinson Disease; Pramipexole

2011
Pramipexole is active in depression tests and modulates monoaminergic transmission, but not brain levels of BDNF in mice.
    European journal of pharmacology, 2012, Feb-29, Volume: 677, Issue:1-3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzothiazoles; Biogenic Monoamines; Brain; Brain-Derived Neurotrophic Factor; Depression; Dopamine Agonists; Emotions; Hindlimb Suspension; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Pramipexole; Synaptic Transmission; Time Factors

2012
New dopamine agonist pramipexole improves parkinsonism and depression in Parkinson's disease.
    Hiroshima journal of medical sciences, 2011, Volume: 60, Issue:4

    Topics: Aged; Aged, 80 and over; Benzothiazoles; Depression; Dopamine Agonists; Female; Humans; Male; Middle Aged; Parkinson Disease; Pramipexole

2011
[Dopamine receptors agonists (mirapex) in the treatment of Parkinson's disease].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2006, Volume: 106, Issue:6

    Topics: Anxiety; Benzothiazoles; Carbidopa; Delayed-Action Preparations; Depression; Dopamine Agonists; Drug Combinations; Drug Therapy, Combination; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pramipexole; Receptors, Dopamine D1; Thiazoles; Treatment Outcome

2006
Current advances in Parkinson's disease.
    Trends in neurosciences, 2001, Volume: 24, Issue:7

    Topics: Antidepressive Agents; Antiparkinson Agents; Benzothiazoles; Brain Stem; Catechols; Depression; Dopamine Agonists; Humans; Levodopa; Nitriles; Parkinson Disease; Pramipexole; Selegiline; Thiazoles

2001